BR112017019290A2 - métodos de modificação enzimática dos glicosídeos de esteviol, glicosídeos de esteviol modificados obtidos deste modo e a sua utilização como edulcorantes - Google Patents
métodos de modificação enzimática dos glicosídeos de esteviol, glicosídeos de esteviol modificados obtidos deste modo e a sua utilização como edulcorantesInfo
- Publication number
- BR112017019290A2 BR112017019290A2 BR112017019290A BR112017019290A BR112017019290A2 BR 112017019290 A2 BR112017019290 A2 BR 112017019290A2 BR 112017019290 A BR112017019290 A BR 112017019290A BR 112017019290 A BR112017019290 A BR 112017019290A BR 112017019290 A2 BR112017019290 A2 BR 112017019290A2
- Authority
- BR
- Brazil
- Prior art keywords
- steviol glycosides
- modified
- sweeteners
- methods
- enzymatic modification
- Prior art date
Links
- 239000004383 Steviol glycoside Substances 0.000 title abstract 6
- 235000019411 steviol glycoside Nutrition 0.000 title abstract 6
- 229930182488 steviol glycoside Natural products 0.000 title abstract 6
- 150000008144 steviol glycosides Chemical class 0.000 title abstract 6
- 235000019202 steviosides Nutrition 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 3
- 235000003599 food sweetener Nutrition 0.000 title abstract 2
- 239000003765 sweetening agent Substances 0.000 title abstract 2
- 230000009144 enzymatic modification Effects 0.000 title 1
- 241000186604 Lactobacillus reuteri Species 0.000 abstract 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
- 229930006000 Sucrose Natural products 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002641 glycemic effect Effects 0.000 abstract 1
- 229940001882 lactobacillus reuteri Drugs 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 239000005720 sucrose Substances 0.000 abstract 1
- 230000006098 transglycosylation Effects 0.000 abstract 1
- 238000005918 transglycosylation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/33—Artificial sweetening agents containing sugars or derivatives
- A23L27/36—Terpene glycosides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/86—Addition of bitterness inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/173—Reuteri
Abstract
a presente invenção se refere, de uma forma geral, à produção de glicosídeos de esteviol. um método para fornecer enzimaticamente um glicosídeo de esteviol modificado é fornecido, o qual compreende a incubação de um substrato de glicosídeo de esteviol na presença de sacarose e glucanucrase gtf180 da cepa de lactobacillus reuteri 180 ou um seu mutante com a atividade de transglicosilação desejada. também são proporcionados glicosídeos de esteviol modificados obtidos por um método da invenção e a sua utilização como edulcorante com baixo teor de glicêmico.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15158421 | 2015-03-10 | ||
PCT/NL2016/050172 WO2016144175A1 (en) | 2015-03-10 | 2016-03-10 | Methods for the enzymatic modification of steviol glycosides, modified steviol glycosides obtainable thereby, and the use thereof as sweeteners |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112017019290A2 true BR112017019290A2 (pt) | 2018-05-02 |
Family
ID=52784894
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017019290A BR112017019290A2 (pt) | 2015-03-10 | 2016-03-10 | métodos de modificação enzimática dos glicosídeos de esteviol, glicosídeos de esteviol modificados obtidos deste modo e a sua utilização como edulcorantes |
Country Status (6)
Country | Link |
---|---|
US (2) | US10731195B2 (pt) |
EP (1) | EP3268487A1 (pt) |
JP (1) | JP6976173B2 (pt) |
CN (1) | CN107532189B (pt) |
BR (1) | BR112017019290A2 (pt) |
WO (1) | WO2016144175A1 (pt) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10517321B2 (en) | 2015-07-10 | 2019-12-31 | Sweet Green Fields USA LLC | Compositions of steviol multiglycosylated derivatives and stevia components |
US11542536B2 (en) | 2016-12-14 | 2023-01-03 | The Coca-Cola Company | Preparing novel steviol glycosides by bioconversion |
CN117752032A (zh) * | 2017-04-25 | 2024-03-26 | 可口可乐公司 | 二氢查耳酮对甜菊醇糖苷和罗汉果苷甜味剂的甜度和味道改善 |
JP6967153B2 (ja) * | 2017-12-15 | 2021-11-17 | シージェイ チェイルジェダン コーポレイション | ラクトバチルス−マリを用いてグルコース転移ステビオール配糖体を製造する方法 |
GB201805576D0 (en) * | 2018-04-04 | 2018-05-16 | Optibiotix Ltd | Sweeteners and methods of production thereof |
US11312948B2 (en) | 2018-05-25 | 2022-04-26 | Bontac Bio-Engineering (Shenzhen) Co., Ltd | Method and enzyme for preparation of enzyme-modified stevia sugar and use of enzyme-modified stevia sugar |
CN108727443A (zh) * | 2018-06-29 | 2018-11-02 | 东台市浩瑞生物科技有限公司 | 提高莱鲍迪苷a1g含量的结晶法、其产品及用途 |
WO2020001516A1 (zh) * | 2018-06-29 | 2020-01-02 | 东台市浩瑞生物科技有限公司 | 甜菊糖苷衍生物莱鲍迪苷a1g、其制备、纯化及应用 |
CN109097423B (zh) * | 2018-08-13 | 2021-05-28 | 江南大学 | 应用交替糖蔗糖酶催化合成单、二葡萄糖基莱鲍迪苷a |
JP2021533729A (ja) * | 2018-08-22 | 2021-12-09 | フイルメニツヒ ソシエテ アノニムFirmenich Sa | テルペングリコシド誘導体およびその使用 |
CN113301810B (zh) * | 2019-01-17 | 2023-08-15 | 北京绿色金可生物技术股份有限公司 | 甜菊醇糖苷的转葡糖基化方法及其甜菊醇糖苷组合物 |
KR20200109775A (ko) * | 2019-03-14 | 2020-09-23 | 씨제이제일제당 (주) | 당전이 스테비오사이드 및 당전이 리바우디오사이드 a를 포함하는 조성물 |
KR102303661B1 (ko) * | 2019-06-14 | 2021-09-23 | 씨제이제일제당 주식회사 | 포도당 전이 효소를 포함하는 포도당 전이 스테비올 배당체 생산용 조성물 및 이를 이용한 포도당 전이 스테비올 배당체 제조방법 |
KR102303415B1 (ko) * | 2019-06-14 | 2021-09-23 | 씨제이제일제당 (주) | 감미 소재 조성물 및 이의 제조 방법 |
WO2021252814A1 (en) * | 2020-06-11 | 2021-12-16 | Corn Products Development, Inc. | Production and uses of oligosaccharides and steviol glycosides |
KR102546737B1 (ko) * | 2020-11-25 | 2023-06-22 | 씨제이제일제당 주식회사 | 포도당 전이 스테비아를 포함하는 감미질이 개선된 조성물 |
GB202112610D0 (en) * | 2021-09-03 | 2021-10-20 | Optibiotix Ltd | Sweetener compositions and methods of production thereof |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US697430A (en) * | 1900-06-12 | 1902-04-15 | Fox Machine Company | Type-writing machine. |
JPS5523756A (en) | 1978-08-07 | 1980-02-20 | Tokyo Shibaura Electric Co | Controller |
US5962678A (en) | 1996-09-13 | 1999-10-05 | Alberta Research Council | Method of extracting selected sweet glycosides from the Stevia rebaudiana plant |
US7923552B2 (en) | 2004-10-18 | 2011-04-12 | SGF Holdings, LLC | High yield method of producing pure rebaudioside A |
US9386797B2 (en) | 2011-02-17 | 2016-07-12 | Purecircle Sdn Bhd | Glucosyl stevia composition |
US8257948B1 (en) * | 2011-02-17 | 2012-09-04 | Purecircle Usa | Method of preparing alpha-glucosyl Stevia composition |
US7862845B2 (en) | 2005-10-11 | 2011-01-04 | Purecircle Sdn Bhd | Process for manufacturing a sweetener and use thereof |
WO2012128775A1 (en) | 2011-03-22 | 2012-09-27 | Purecircle Usa | Glucosylated steviol glycoside composition as a taste and flavor enhancer |
US8791253B2 (en) | 2006-06-19 | 2014-07-29 | The Coca-Cola Company | Rebaudioside A composition and method for purifying rebaudioside A |
US20130071521A1 (en) | 2007-03-14 | 2013-03-21 | Pepsico, Inc. | Rebaudioside d sweeteners and food products sweetened with rebaudioside d |
KR20130014227A (ko) * | 2011-07-29 | 2013-02-07 | 한국생명공학연구원 | 신규한 α-글루코실 스테비오사이드 및 이의 제조 방법 |
EP2770843B1 (en) * | 2011-10-24 | 2017-08-09 | Givaudan SA | Sweetness enhancing composition comprising stevioside and rebaudioside a |
CN102492757B (zh) * | 2011-11-25 | 2014-04-09 | 中国农业大学 | 一种用β-环糊精葡萄糖基转移酶提高甜菊糖苷味质的方法 |
RU2599166C2 (ru) | 2011-12-19 | 2016-10-10 | Дзе Кока-Кола Компани | Способы очистки стевиоловых гликозидов и их применение |
CN102492673B (zh) * | 2011-12-28 | 2013-01-23 | 江南大学 | 一种柠檬明串珠菌发酵生产交替糖蔗糖酶的方法及应用 |
AU2013211605B2 (en) * | 2012-01-23 | 2017-04-06 | Dsm Ip Assets B.V. | Diterpene production |
CN103974628B (zh) * | 2012-05-22 | 2019-04-05 | 谱赛科有限责任公司 | 高纯度的甜菊醇糖苷 |
CN102940183A (zh) * | 2012-11-09 | 2013-02-27 | 江南大学 | 一种调控提高甜菊糖味质的生物加工方法 |
CA3171770A1 (en) | 2013-02-06 | 2014-08-14 | Evolva Sa | Methods for improved production of rebaudioside d and rebaudioside m |
-
2016
- 2016-03-10 JP JP2017547452A patent/JP6976173B2/ja active Active
- 2016-03-10 BR BR112017019290A patent/BR112017019290A2/pt active Search and Examination
- 2016-03-10 WO PCT/NL2016/050172 patent/WO2016144175A1/en active Application Filing
- 2016-03-10 US US15/556,846 patent/US10731195B2/en active Active
- 2016-03-10 CN CN201680022567.6A patent/CN107532189B/zh active Active
- 2016-03-10 EP EP16718510.7A patent/EP3268487A1/en active Pending
-
2020
- 2020-06-12 US US16/899,709 patent/US20200325515A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP6976173B2 (ja) | 2021-12-08 |
JP2018509902A (ja) | 2018-04-12 |
EP3268487A1 (en) | 2018-01-17 |
WO2016144175A1 (en) | 2016-09-15 |
US20200325515A1 (en) | 2020-10-15 |
US20180044708A1 (en) | 2018-02-15 |
US10731195B2 (en) | 2020-08-04 |
CN107532189B (zh) | 2021-12-17 |
CN107532189A (zh) | 2018-01-02 |
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] |