BR112018002371A2 - método para a produção de glicosídeo(s) de esteviol - Google Patents

método para a produção de glicosídeo(s) de esteviol

Info

Publication number
BR112018002371A2
BR112018002371A2 BR112018002371A BR112018002371A BR112018002371A2 BR 112018002371 A2 BR112018002371 A2 BR 112018002371A2 BR 112018002371 A BR112018002371 A BR 112018002371A BR 112018002371 A BR112018002371 A BR 112018002371A BR 112018002371 A2 BR112018002371 A2 BR 112018002371A2
Authority
BR
Brazil
Prior art keywords
production
steviol glycoside
yeast
rebaudioside
polysaccharides
Prior art date
Application number
BR112018002371A
Other languages
English (en)
Inventor
M Fosmer Arlene
C Anderson James
Liu Carlson Ting
Original Assignee
Cargill Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cargill Inc filed Critical Cargill Inc
Publication of BR112018002371A2 publication Critical patent/BR112018002371A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A23L27/36—Terpene glycosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

são divulgados métodos para a produção de glicosídeos de esteviol, tais como rebaudiosídeo d e rebaudiosídeo m, utilizando levedura engenheirada. os métodos incluem cultivar levedura em fontes de carbono não fermentativas. outros métodos incluem cultivar levedura em um ou mais polissacarídeos em que ocorre sacarificação e fermentação dos polissacarídeos simultaneamente.
BR112018002371A 2015-08-06 2016-08-08 método para a produção de glicosídeo(s) de esteviol BR112018002371A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562201941P 2015-08-06 2015-08-06
PCT/US2016/046072 WO2017024313A1 (en) 2015-08-06 2016-08-08 Fermentation methods for producing steviol glycosides

Publications (1)

Publication Number Publication Date
BR112018002371A2 true BR112018002371A2 (pt) 2019-09-17

Family

ID=57943772

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018002371A BR112018002371A2 (pt) 2015-08-06 2016-08-08 método para a produção de glicosídeo(s) de esteviol

Country Status (8)

Country Link
US (1) US10844414B2 (pt)
EP (1) EP3331373A4 (pt)
JP (1) JP2018521680A (pt)
CN (1) CN107920548A (pt)
AU (1) AU2016301190A1 (pt)
BR (1) BR112018002371A2 (pt)
CA (1) CA2994288A1 (pt)
WO (1) WO2017024313A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
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CA2899276C (en) * 2013-02-06 2022-11-01 Evolva Sa Methods for improved production of rebaudioside d and rebaudioside m
EP4063513A1 (en) 2015-05-29 2022-09-28 Cargill, Incorporated Heat treatment to produce glycosides
WO2016196321A1 (en) 2015-05-29 2016-12-08 Cargill, Incorporated Fermentation methods for producing steviol glycosides using high ph and compositions obtained therefrom
CN107614677A (zh) 2015-05-29 2018-01-19 嘉吉公司 用于使用多阶段进料生产甜菊醇糖苷的发酵方法
WO2018114995A1 (en) * 2016-12-22 2018-06-28 Dsm Ip Assets B.V. Fermentation process for producing steviol glycosides
CA3050310A1 (en) 2017-02-03 2018-08-09 Codexis, Inc. Engineered glycosyltransferases and steviol glycoside glucosylation methods
PE20200291A1 (es) * 2017-05-15 2020-02-05 Purecircle Usa Inc Glicosidos de esteviol de alta pureza
US11998032B2 (en) 2017-06-08 2024-06-04 Suntory Holdings Limited Food or beverage with increased sweetness
AU2018294258A1 (en) * 2017-06-30 2020-02-06 Conagen Inc. Hydrolysis of steviol glycosides by beta-glucosidase
CN108841897A (zh) * 2018-07-16 2018-11-20 安徽民祯生物工程有限公司 一种用于生产海藻糖的酵母培养方法
US11125288B2 (en) 2018-08-21 2021-09-21 Akebono Brake Industry Co., Ltd Disc brake system
SG11202105896PA (en) * 2018-12-07 2021-07-29 Suntory Holdings Ltd Effervescent beverage in which quality of taste resulting from sugars and sweeteners is improved
CN113163812A (zh) * 2018-12-07 2021-07-23 三得利控股株式会社 糖及甜味剂所呈现的味质得到改善的风味水
JP7479296B2 (ja) * 2018-12-07 2024-05-08 サントリーホールディングス株式会社 糖および甘味料の呈する味質が改善した果汁飲料
CN113163811B (zh) * 2018-12-07 2024-03-26 三得利控股株式会社 糖及甜味剂所呈现的味质得到改善的发泡性饮料
AU2019391593A1 (en) * 2018-12-07 2021-07-29 Suntory Holdings Limited Flavor water having improved taste qualities of sugar and sweetener

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AU7610200A (en) 1999-09-30 2001-05-10 Cognis Corporation Improved fermentation process
EP1178118A1 (en) 2000-08-02 2002-02-06 Dsm N.V. Isolation of microbial oils
ATE426674T1 (de) 2000-11-03 2009-04-15 Genentech Inc Stoffwechselanderungen in garungen zur produktion rekombinanter proteine
US7923552B2 (en) 2004-10-18 2011-04-12 SGF Holdings, LLC High yield method of producing pure rebaudioside A
US7923231B2 (en) 2004-12-17 2011-04-12 Cargill, Incorporated Production of glucuronic acid using myo-inositol oxygenase from cryptococcus neoformans
US8318459B2 (en) 2011-02-17 2012-11-27 Purecircle Usa Glucosyl stevia composition
WO2008037735A1 (en) 2006-09-27 2008-04-03 Novo Nordisk A/S Method for making maturated insulin polypeptides
CA2700685A1 (en) 2007-09-27 2009-04-02 Mascoma Corporation Progressive fermentation of lignocellulosic biomass
WO2009140394A1 (en) 2008-05-13 2009-11-19 Cargill, Incorporated Separation of rebaudioside a from stevia glycosides using chromatography
CN102812129B (zh) 2009-11-10 2015-08-26 麻省理工学院 用于从类异戊二烯途径生产化学和医药产品的微生物工程
WO2011112892A1 (en) 2010-03-12 2011-09-15 Purecircle Usa Inc. High-purity steviol glycosides
BR122021005283B1 (pt) 2010-06-02 2022-02-22 Evolva, Inc Hospedeiro recombinante que compreende genes recombinantes para produção deesteviol ou glicosídeo de esteviol, método para produzir esteviol, glicosídeo de esteviol ou composição de glicosídeo de esteviol e método para sintetizar esteviol ou glicosídeo de esteviol
US9284570B2 (en) 2010-11-30 2016-03-15 Massachusetts Institute Of Technology Microbial production of natural sweeteners, diterpenoid steviol glycosides
CN103348008B (zh) 2010-12-23 2016-06-01 国际壳牌研究有限公司 产生脂酰CoA衍生物的基因破坏子
EP3009508B1 (en) 2011-08-08 2020-11-25 Evolva SA Recombinant production of steviol glycosides
ES2971273T3 (es) 2011-12-19 2024-06-04 Coca Cola Co Bebida que comprende rebaudiósido X
EA201400836A8 (ru) 2012-01-23 2016-03-31 ДСМ АйПи АССЕТС Б.В. Получение дитерпена
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JP6189828B2 (ja) * 2012-03-27 2017-08-30 サントリーホールディングス株式会社 ステビオール配糖体の製造方法
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CA2899276C (en) 2013-02-06 2022-11-01 Evolva Sa Methods for improved production of rebaudioside d and rebaudioside m
US10017804B2 (en) 2013-02-11 2018-07-10 Evolva Sa Efficient production of steviol glycosides in recombinant hosts
US10189892B2 (en) 2013-03-15 2019-01-29 Alderbio Holdings Llc Fermentation process for antibody production
AU2014273055A1 (en) 2013-05-31 2015-12-17 Dsm Ip Assets B.V. Microorganisms for diterpene production
EP3004365A1 (en) 2013-05-31 2016-04-13 DSM IP Assets B.V. Extracellular diterpene production
BR112016000745B1 (pt) 2013-07-15 2021-01-05 Dsm Ip Assets B.V. processo para a preparação de rebaudiosídeo m
CN104342432A (zh) * 2013-07-23 2015-02-11 南京诺云生物科技有限公司 一种利用基因工程改造酶制备萜类化合物的方法
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US20160213039A1 (en) 2013-07-31 2016-07-28 Dsm Ip Assets B.V. Steviol glycosides
EP2902481A1 (en) 2014-01-31 2015-08-05 Danstar Ferment AG Method for obtaining low ethanol-producing yeast strains, yeast strains obtained therefrom and their use
EP4063513A1 (en) 2015-05-29 2022-09-28 Cargill, Incorporated Heat treatment to produce glycosides
CN107614677A (zh) 2015-05-29 2018-01-19 嘉吉公司 用于使用多阶段进料生产甜菊醇糖苷的发酵方法
WO2016196321A1 (en) 2015-05-29 2016-12-08 Cargill, Incorporated Fermentation methods for producing steviol glycosides using high ph and compositions obtained therefrom

Also Published As

Publication number Publication date
US10844414B2 (en) 2020-11-24
JP2018521680A (ja) 2018-08-09
CA2994288A1 (en) 2017-02-09
CN107920548A (zh) 2018-04-17
EP3331373A1 (en) 2018-06-13
WO2017024313A1 (en) 2017-02-09
EP3331373A4 (en) 2019-07-10
US20180230504A1 (en) 2018-08-16
AU2016301190A1 (en) 2018-02-15

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B350 Update of information on the portal [chapter 15.35 patent gazette]