KR20120050469A - 포르피로모나스 긴기발리스 폴리펩티드 - Google Patents

포르피로모나스 긴기발리스 폴리펩티드 Download PDF

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Publication number
KR20120050469A
KR20120050469A KR1020127005748A KR20127005748A KR20120050469A KR 20120050469 A KR20120050469 A KR 20120050469A KR 1020127005748 A KR1020127005748 A KR 1020127005748A KR 20127005748 A KR20127005748 A KR 20127005748A KR 20120050469 A KR20120050469 A KR 20120050469A
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KR
South Korea
Prior art keywords
seq
polypeptide
gingivalis
identity
protein
Prior art date
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Ceased
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KR1020127005748A
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English (en)
Korean (ko)
Inventor
재클린 맥클러스키
로베르 샤를르보아
로랑스 크메뉘에
제레미 예톤
마이클 리치
Original Assignee
사노피 파스퇴르 리미티드
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Publication of KR20120050469A publication Critical patent/KR20120050469A/ko
Ceased legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56955—Bacteria involved in periodontal diseases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0216—Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1257—Gram-negative bacteria from Bacteridaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/21—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
KR1020127005748A 2009-08-02 2010-07-30 포르피로모나스 긴기발리스 폴리펩티드 Ceased KR20120050469A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23071709P 2009-08-02 2009-08-02
US61/230,717 2009-08-02

Publications (1)

Publication Number Publication Date
KR20120050469A true KR20120050469A (ko) 2012-05-18

Family

ID=43543841

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020127005748A Ceased KR20120050469A (ko) 2009-08-02 2010-07-30 포르피로모나스 긴기발리스 폴리펩티드

Country Status (14)

Country Link
US (1) US9366673B2 (enExample)
EP (1) EP2462160A4 (enExample)
JP (2) JP5876411B2 (enExample)
KR (1) KR20120050469A (enExample)
CN (1) CN102712693A (enExample)
AR (1) AR085167A1 (enExample)
AU (1) AU2010281313B2 (enExample)
BR (1) BR112012002429A2 (enExample)
CA (1) CA2769231A1 (enExample)
IL (1) IL217861A0 (enExample)
MX (1) MX2012001495A (enExample)
RU (1) RU2012107993A (enExample)
WO (1) WO2011014947A1 (enExample)
ZA (1) ZA201200799B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107266582B (zh) * 2008-08-29 2021-09-10 口腔健康澳洲私人有限公司 牙龈卟啉单胞菌感染的预防、治疗和诊断
MY162557A (en) 2010-02-26 2017-06-15 Oral Health Australia Pty Ltd Treatment or prevention of infection
CA2894903A1 (en) * 2012-12-14 2014-06-19 Sanofi Pasteur, Ltd. Methods for assessing immunogenicity
EP3303385A2 (en) * 2015-05-27 2018-04-11 Merial, Inc. Compositions containing antimicrobial igy antibodies, for treatment and prevention of disorders and diseases caused by oral health compromising (ohc) microorganisms
SG11202003147XA (en) 2017-10-12 2020-05-28 Vaxcyte Inc Periodontitis vaccine and related compositions and method of use
CN118696130A (zh) * 2021-11-17 2024-09-24 纳尔德生物有限责任公司 用于实时细胞药物-靶标接合的系统和方法
CN114469863B (zh) * 2021-11-26 2023-09-26 南方医科大学南方医院 甾醇脂质体作为牙髓和牙本质药物传递系统的应用
CN116474096A (zh) * 2022-01-14 2023-07-25 中山大学附属口腔医院 靶向牙龈卟啉单胞菌RgpB在结直肠癌的治疗及预防中的应用
EP4514843A1 (en) * 2022-04-26 2025-03-05 K-Bio Investment, LLC Formulation for antigen-binding molecules that bind to porphyromonas gingivalis
AU2022477921A1 (en) * 2022-09-16 2025-04-24 Qjm Bioinformation Ltd Antibodies and method of use for p. gingivalis
WO2025017202A2 (en) 2023-07-19 2025-01-23 Sanofi Porphyromonas gingivalis antigenic constructs
CN116751292B (zh) * 2023-07-31 2024-05-14 河南大学 牙龈卟啉单胞菌Mfa1单克隆抗体及其应用
CN119424610A (zh) * 2024-12-05 2025-02-14 重庆师范大学 具备抗衰老活性的重组蛋白制剂及其制备方法、应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000507245A (ja) * 1996-03-22 2000-06-13 ユニバーシティー オブ ジョージア リサーチ ファウンデーション，インコーポレイテッド Ｐｏｒｐｈｙｒｏｍｏｎａｓ ｇｉｎｇｉｖａｌｉｓペプチドを含む免疫原性組成物および方法
AUPN901296A0 (en) * 1996-03-29 1996-04-26 University Of Melbourne, The Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis
ATE534742T1 (de) * 1997-12-10 2011-12-15 Csl Ltd Polypeptide und nukleinsäuren von phorphorymonas gingivalis
JP2003192616A (ja) * 2001-12-27 2003-07-09 Univ Nihon 歯周病用ｄｎａワクチン
JP2003286191A (ja) * 2002-03-27 2003-10-07 Univ Nihon 歯周病用粘膜免疫ワクチン
JPWO2004083425A1 (ja) * 2003-03-17 2006-06-22 麒麟麦酒株式会社 歯周病治療剤
JP2005179301A (ja) * 2003-12-22 2005-07-07 Univ Nihon 歯周病用経皮免疫ワクチン
US20100092471A1 (en) 2006-06-27 2010-04-15 Oral Health Australia Pty Ltd Porphyromonas Gingivalis Polypeptides Useful in the Prevention of Periodontal Disease
CN101842486A (zh) * 2007-07-12 2010-09-22 口腔健康澳洲私人有限公司 生物膜的免疫治疗

Also Published As

Publication number Publication date
JP2013501007A (ja) 2013-01-10
AU2010281313B2 (en) 2015-09-03
WO2011014947A1 (en) 2011-02-10
JP2015178533A (ja) 2015-10-08
JP5876411B2 (ja) 2016-03-02
US9366673B2 (en) 2016-06-14
US20120156211A1 (en) 2012-06-21
CN102712693A (zh) 2012-10-03
AU2010281313A1 (en) 2012-03-08
IL217861A0 (en) 2012-03-29
EP2462160A1 (en) 2012-06-13
AR085167A1 (es) 2013-09-18
RU2012107993A (ru) 2013-09-10
BR112012002429A2 (pt) 2016-11-08
EP2462160A4 (en) 2013-04-24
ZA201200799B (en) 2013-06-26
MX2012001495A (es) 2012-08-03
CA2769231A1 (en) 2011-02-10

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