AU2010281313B2 - Porphyromonas gingivalis polypeptides - Google Patents

Porphyromonas gingivalis polypeptides Download PDF

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Publication number
AU2010281313B2
AU2010281313B2 AU2010281313A AU2010281313A AU2010281313B2 AU 2010281313 B2 AU2010281313 B2 AU 2010281313B2 AU 2010281313 A AU2010281313 A AU 2010281313A AU 2010281313 A AU2010281313 A AU 2010281313A AU 2010281313 B2 AU2010281313 B2 AU 2010281313B2
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AU
Australia
Prior art keywords
gingivalis
polypeptide
seq
subject
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2010281313A
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English (en)
Other versions
AU2010281313A1 (en
Inventor
Robert Charlebois
Michael Leach
Jacqueline Mccluskey
Laurence Quemenuer
Jeremy Yethon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur Ltd
Original Assignee
Sanofi Pasteur Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of AU2010281313A1 publication Critical patent/AU2010281313A1/en
Application granted granted Critical
Publication of AU2010281313B2 publication Critical patent/AU2010281313B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56955Bacteria involved in periodontal diseases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0216Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Gram-negative bacteria
    • C07K16/1257Gram-negative bacteria from Bacteridaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/21Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AU2010281313A 2009-08-02 2010-07-30 Porphyromonas gingivalis polypeptides Ceased AU2010281313B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23071709P 2009-08-02 2009-08-02
US61/230,717 2009-08-02
PCT/CA2010/001177 WO2011014947A1 (en) 2009-08-02 2010-07-30 Porphyromonas gingivalis polypeptides

Publications (2)

Publication Number Publication Date
AU2010281313A1 AU2010281313A1 (en) 2012-03-08
AU2010281313B2 true AU2010281313B2 (en) 2015-09-03

Family

ID=43543841

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010281313A Ceased AU2010281313B2 (en) 2009-08-02 2010-07-30 Porphyromonas gingivalis polypeptides

Country Status (14)

Country Link
US (1) US9366673B2 (enExample)
EP (1) EP2462160A4 (enExample)
JP (2) JP5876411B2 (enExample)
KR (1) KR20120050469A (enExample)
CN (1) CN102712693A (enExample)
AR (1) AR085167A1 (enExample)
AU (1) AU2010281313B2 (enExample)
BR (1) BR112012002429A2 (enExample)
CA (1) CA2769231A1 (enExample)
IL (1) IL217861A0 (enExample)
MX (1) MX2012001495A (enExample)
RU (1) RU2012107993A (enExample)
WO (1) WO2011014947A1 (enExample)
ZA (1) ZA201200799B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107266582B (zh) * 2008-08-29 2021-09-10 口腔健康澳洲私人有限公司 牙龈卟啉单胞菌感染的预防、治疗和诊断
MY162557A (en) 2010-02-26 2017-06-15 Oral Health Australia Pty Ltd Treatment or prevention of infection
CA2894903A1 (en) * 2012-12-14 2014-06-19 Sanofi Pasteur, Ltd. Methods for assessing immunogenicity
EP3303385A2 (en) * 2015-05-27 2018-04-11 Merial, Inc. Compositions containing antimicrobial igy antibodies, for treatment and prevention of disorders and diseases caused by oral health compromising (ohc) microorganisms
SG11202003147XA (en) 2017-10-12 2020-05-28 Vaxcyte Inc Periodontitis vaccine and related compositions and method of use
CN118696130A (zh) * 2021-11-17 2024-09-24 纳尔德生物有限责任公司 用于实时细胞药物-靶标接合的系统和方法
CN114469863B (zh) * 2021-11-26 2023-09-26 南方医科大学南方医院 甾醇脂质体作为牙髓和牙本质药物传递系统的应用
CN116474096A (zh) * 2022-01-14 2023-07-25 中山大学附属口腔医院 靶向牙龈卟啉单胞菌RgpB在结直肠癌的治疗及预防中的应用
EP4514843A1 (en) * 2022-04-26 2025-03-05 K-Bio Investment, LLC Formulation for antigen-binding molecules that bind to porphyromonas gingivalis
AU2022477921A1 (en) * 2022-09-16 2025-04-24 Qjm Bioinformation Ltd Antibodies and method of use for p. gingivalis
WO2025017202A2 (en) 2023-07-19 2025-01-23 Sanofi Porphyromonas gingivalis antigenic constructs
CN116751292B (zh) * 2023-07-31 2024-05-14 河南大学 牙龈卟啉单胞菌Mfa1单克隆抗体及其应用
CN119424610A (zh) * 2024-12-05 2025-02-14 重庆师范大学 具备抗衰老活性的重组蛋白制剂及其制备方法、应用

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003192616A (ja) * 2001-12-27 2003-07-09 Univ Nihon 歯周病用dnaワクチン
JP2003286191A (ja) * 2002-03-27 2003-10-07 Univ Nihon 歯周病用粘膜免疫ワクチン
JP2005179301A (ja) * 2003-12-22 2005-07-07 Univ Nihon 歯周病用経皮免疫ワクチン
US20070036734A1 (en) * 2003-03-17 2007-02-15 Kirin Beer Kabushiki Kaisha Therapeutic agent for periodontal disease
WO2008000028A1 (en) * 2006-06-27 2008-01-03 Oral Health Australia Pty Ltd Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000507245A (ja) * 1996-03-22 2000-06-13 ユニバーシティー オブ ジョージア リサーチ ファウンデーション,インコーポレイテッド Porphyromonas gingivalisペプチドを含む免疫原性組成物および方法
AUPN901296A0 (en) * 1996-03-29 1996-04-26 University Of Melbourne, The Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis
ATE534742T1 (de) * 1997-12-10 2011-12-15 Csl Ltd Polypeptide und nukleinsäuren von phorphorymonas gingivalis
CN101842486A (zh) * 2007-07-12 2010-09-22 口腔健康澳洲私人有限公司 生物膜的免疫治疗

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003192616A (ja) * 2001-12-27 2003-07-09 Univ Nihon 歯周病用dnaワクチン
JP2003286191A (ja) * 2002-03-27 2003-10-07 Univ Nihon 歯周病用粘膜免疫ワクチン
US20070036734A1 (en) * 2003-03-17 2007-02-15 Kirin Beer Kabushiki Kaisha Therapeutic agent for periodontal disease
JP2005179301A (ja) * 2003-12-22 2005-07-07 Univ Nihon 歯周病用経皮免疫ワクチン
WO2008000028A1 (en) * 2006-06-27 2008-01-03 Oral Health Australia Pty Ltd Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease

Also Published As

Publication number Publication date
JP2013501007A (ja) 2013-01-10
WO2011014947A1 (en) 2011-02-10
JP2015178533A (ja) 2015-10-08
JP5876411B2 (ja) 2016-03-02
KR20120050469A (ko) 2012-05-18
US9366673B2 (en) 2016-06-14
US20120156211A1 (en) 2012-06-21
CN102712693A (zh) 2012-10-03
AU2010281313A1 (en) 2012-03-08
IL217861A0 (en) 2012-03-29
EP2462160A1 (en) 2012-06-13
AR085167A1 (es) 2013-09-18
RU2012107993A (ru) 2013-09-10
BR112012002429A2 (pt) 2016-11-08
EP2462160A4 (en) 2013-04-24
ZA201200799B (en) 2013-06-26
MX2012001495A (es) 2012-08-03
CA2769231A1 (en) 2011-02-10

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