CN102712693A - 牙龈卟啉单胞菌多肽 - Google Patents

牙龈卟啉单胞菌多肽 Download PDF

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Publication number
CN102712693A
CN102712693A CN2010800451190A CN201080045119A CN102712693A CN 102712693 A CN102712693 A CN 102712693A CN 2010800451190 A CN2010800451190 A CN 2010800451190A CN 201080045119 A CN201080045119 A CN 201080045119A CN 102712693 A CN102712693 A CN 102712693A
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CN
China
Prior art keywords
polypeptide
seq
porphyromonas gingivalis
identity
albumen
Prior art date
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Pending
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CN2010800451190A
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English (en)
Chinese (zh)
Inventor
J·麦克卢斯基
R·沙尔博瓦
L·克梅诺伊尔
J·耶松
M·利奇
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Sanofi Pasteur Ltd
Original Assignee
Aventis Pasteur Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pasteur Ltd filed Critical Aventis Pasteur Ltd
Publication of CN102712693A publication Critical patent/CN102712693A/zh
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56955Bacteria involved in periodontal diseases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0216Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1257Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Bacteridaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/21Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN2010800451190A 2009-08-02 2010-07-30 牙龈卟啉单胞菌多肽 Pending CN102712693A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23071709P 2009-08-02 2009-08-02
US61/230717 2009-08-02
PCT/CA2010/001177 WO2011014947A1 (en) 2009-08-02 2010-07-30 Porphyromonas gingivalis polypeptides

Publications (1)

Publication Number Publication Date
CN102712693A true CN102712693A (zh) 2012-10-03

Family

ID=43543841

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800451190A Pending CN102712693A (zh) 2009-08-02 2010-07-30 牙龈卟啉单胞菌多肽

Country Status (14)

Country Link
US (1) US9366673B2 (enExample)
EP (1) EP2462160A4 (enExample)
JP (2) JP5876411B2 (enExample)
KR (1) KR20120050469A (enExample)
CN (1) CN102712693A (enExample)
AR (1) AR085167A1 (enExample)
AU (1) AU2010281313B2 (enExample)
BR (1) BR112012002429A2 (enExample)
CA (1) CA2769231A1 (enExample)
IL (1) IL217861A0 (enExample)
MX (1) MX2012001495A (enExample)
RU (1) RU2012107993A (enExample)
WO (1) WO2011014947A1 (enExample)
ZA (1) ZA201200799B (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114469863A (zh) * 2021-11-26 2022-05-13 南方医科大学南方医院 甾醇脂质体作为牙髓和牙本质药物传递系统的应用
CN116751292A (zh) * 2023-07-31 2023-09-15 河南大学 牙龈卟啉单胞菌Mfa1单克隆抗体及其应用
CN119424610A (zh) * 2024-12-05 2025-02-14 重庆师范大学 具备抗衰老活性的重组蛋白制剂及其制备方法、应用
EP4433610A4 (en) * 2021-11-17 2025-12-03 Nerd Bio Llc SYSTEMS AND METHODS FOR REAL-TIME CELLULAR ENGAGEMENT BETWEEN TARGET AND DRUG

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8871213B2 (en) 2008-08-29 2014-10-28 Oral Health Australia Pty Ltd Prevention, treatment and diagnosis of P. gingivalis infection
MY162557A (en) * 2010-02-26 2017-06-15 Oral Health Australia Pty Ltd Treatment or prevention of infection
CA2894903A1 (en) * 2012-12-14 2014-06-19 Sanofi Pasteur, Ltd. Methods for assessing immunogenicity
EP3303385A2 (en) * 2015-05-27 2018-04-11 Merial, Inc. Compositions containing antimicrobial igy antibodies, for treatment and prevention of disorders and diseases caused by oral health compromising (ohc) microorganisms
US10835590B2 (en) 2017-10-12 2020-11-17 Vaxcyte, Inc. Periodontitis vaccine and related compositions and methods of use
CN116474096A (zh) * 2022-01-14 2023-07-25 中山大学附属口腔医院 靶向牙龈卟啉单胞菌RgpB在结直肠癌的治疗及预防中的应用
CA3250494A1 (en) * 2022-04-26 2023-11-02 Keystone Bio Inc FORMULATION FOR ANTIGEN-BINDING MOLECULES THAT BIND TO PORPHYROMONAS GINGIVALIS
AU2022477921A1 (en) * 2022-09-16 2025-04-24 Qjm Bioinformation Ltd Antibodies and method of use for p. gingivalis
AR133317A1 (es) 2023-07-19 2025-09-17 Sanofi Sa Constructos antigénicos de porphyromonas gingivalis

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003192616A (ja) * 2001-12-27 2003-07-09 Univ Nihon 歯周病用dnaワクチン
JP2003286191A (ja) * 2002-03-27 2003-10-07 Univ Nihon 歯周病用粘膜免疫ワクチン
JP2005179301A (ja) * 2003-12-22 2005-07-07 Univ Nihon 歯周病用経皮免疫ワクチン
WO2008000028A1 (en) * 2006-06-27 2008-01-03 Oral Health Australia Pty Ltd Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU742668B2 (en) * 1996-03-22 2002-01-10 Morehouse School Of Medicine Immunogenic compositions comprising porphyromonas gingivalis peptides and methods
AUPN901296A0 (en) * 1996-03-29 1996-04-26 University Of Melbourne, The Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis
EP2264176A1 (en) * 1997-12-10 2010-12-22 CSL Limited Porphorymonas gingivalis polypeptides and polynucleotides
WO2004083425A1 (ja) * 2003-03-17 2004-09-30 Kirin Beer Kabushiki Kaisha 歯周病治療剤
EP2604692A1 (en) * 2007-07-12 2013-06-19 Oral Health Australia Pty Ltd Immunology treatment for biofilms

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003192616A (ja) * 2001-12-27 2003-07-09 Univ Nihon 歯周病用dnaワクチン
JP2003286191A (ja) * 2002-03-27 2003-10-07 Univ Nihon 歯周病用粘膜免疫ワクチン
JP2005179301A (ja) * 2003-12-22 2005-07-07 Univ Nihon 歯周病用経皮免疫ワクチン
WO2008000028A1 (en) * 2006-06-27 2008-01-03 Oral Health Australia Pty Ltd Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4433610A4 (en) * 2021-11-17 2025-12-03 Nerd Bio Llc SYSTEMS AND METHODS FOR REAL-TIME CELLULAR ENGAGEMENT BETWEEN TARGET AND DRUG
CN114469863A (zh) * 2021-11-26 2022-05-13 南方医科大学南方医院 甾醇脂质体作为牙髓和牙本质药物传递系统的应用
CN114469863B (zh) * 2021-11-26 2023-09-26 南方医科大学南方医院 甾醇脂质体作为牙髓和牙本质药物传递系统的应用
CN116751292A (zh) * 2023-07-31 2023-09-15 河南大学 牙龈卟啉单胞菌Mfa1单克隆抗体及其应用
CN116751292B (zh) * 2023-07-31 2024-05-14 河南大学 牙龈卟啉单胞菌Mfa1单克隆抗体及其应用
CN119424610A (zh) * 2024-12-05 2025-02-14 重庆师范大学 具备抗衰老活性的重组蛋白制剂及其制备方法、应用

Also Published As

Publication number Publication date
AU2010281313A1 (en) 2012-03-08
KR20120050469A (ko) 2012-05-18
AR085167A1 (es) 2013-09-18
AU2010281313B2 (en) 2015-09-03
JP5876411B2 (ja) 2016-03-02
EP2462160A4 (en) 2013-04-24
CA2769231A1 (en) 2011-02-10
EP2462160A1 (en) 2012-06-13
JP2013501007A (ja) 2013-01-10
ZA201200799B (en) 2013-06-26
MX2012001495A (es) 2012-08-03
JP2015178533A (ja) 2015-10-08
US9366673B2 (en) 2016-06-14
IL217861A0 (en) 2012-03-29
WO2011014947A1 (en) 2011-02-10
BR112012002429A2 (pt) 2016-11-08
RU2012107993A (ru) 2013-09-10
US20120156211A1 (en) 2012-06-21

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