JP5876411B2 - ポルフィロモナス・ジンジバリス(Porphyromonasgingivalis)ポリペプチド - Google Patents

ポルフィロモナス・ジンジバリス(Porphyromonasgingivalis)ポリペプチド Download PDF

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Publication number
JP5876411B2
JP5876411B2 JP2012523169A JP2012523169A JP5876411B2 JP 5876411 B2 JP5876411 B2 JP 5876411B2 JP 2012523169 A JP2012523169 A JP 2012523169A JP 2012523169 A JP2012523169 A JP 2012523169A JP 5876411 B2 JP5876411 B2 JP 5876411B2
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Prior art keywords
gingivalis
polypeptide
seq
protein
composition
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JP2012523169A
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Japanese (ja)
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JP2013501007A5 (enExample
JP2013501007A (ja
Inventor
マクラスキー,ジャクリーン
チャールボイス,ロバート
ケムヌール,ロランス
イェトホン,ジェレミー
リーチ,マイケル
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Sanofi Pasteur Ltd
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Sanofi Pasteur Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56955Bacteria involved in periodontal diseases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0216Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1257Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Bacteridaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/21Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
JP2012523169A 2009-08-02 2010-07-30 ポルフィロモナス・ジンジバリス(Porphyromonasgingivalis)ポリペプチド Expired - Fee Related JP5876411B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23071709P 2009-08-02 2009-08-02
US61/230,717 2009-08-02
PCT/CA2010/001177 WO2011014947A1 (en) 2009-08-02 2010-07-30 Porphyromonas gingivalis polypeptides

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015133497A Division JP2015178533A (ja) 2009-08-02 2015-07-02 ポルフィロモナス・ジンジバリス(Porphyromonasgingivalis)ポリペプチド

Publications (3)

Publication Number Publication Date
JP2013501007A JP2013501007A (ja) 2013-01-10
JP2013501007A5 JP2013501007A5 (enExample) 2013-09-12
JP5876411B2 true JP5876411B2 (ja) 2016-03-02

Family

ID=43543841

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012523169A Expired - Fee Related JP5876411B2 (ja) 2009-08-02 2010-07-30 ポルフィロモナス・ジンジバリス(Porphyromonasgingivalis)ポリペプチド
JP2015133497A Pending JP2015178533A (ja) 2009-08-02 2015-07-02 ポルフィロモナス・ジンジバリス(Porphyromonasgingivalis)ポリペプチド

Family Applications After (1)

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JP2015133497A Pending JP2015178533A (ja) 2009-08-02 2015-07-02 ポルフィロモナス・ジンジバリス(Porphyromonasgingivalis)ポリペプチド

Country Status (14)

Country Link
US (1) US9366673B2 (enExample)
EP (1) EP2462160A4 (enExample)
JP (2) JP5876411B2 (enExample)
KR (1) KR20120050469A (enExample)
CN (1) CN102712693A (enExample)
AR (1) AR085167A1 (enExample)
AU (1) AU2010281313B2 (enExample)
BR (1) BR112012002429A2 (enExample)
CA (1) CA2769231A1 (enExample)
IL (1) IL217861A0 (enExample)
MX (1) MX2012001495A (enExample)
RU (1) RU2012107993A (enExample)
WO (1) WO2011014947A1 (enExample)
ZA (1) ZA201200799B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0917321A2 (pt) 2008-08-29 2015-11-17 Oral Health Australia Pty Ltd prevenção, tratamento e diagnóstico de infecção por p. gingivalis
MY162557A (en) * 2010-02-26 2017-06-15 Oral Health Australia Pty Ltd Treatment or prevention of infection
CA2894903A1 (en) * 2012-12-14 2014-06-19 Sanofi Pasteur, Ltd. Methods for assessing immunogenicity
AU2016267047A1 (en) * 2015-05-27 2017-12-21 Merial, Inc. Compositions containing antimicrobial IgY antibodies, for treatment and prevention of disorders and diseases caused by oral health compromising (OHC) microorganisms
EA202090908A1 (ru) 2017-10-12 2020-10-29 Ваксайт, Инк. Вакцина и связанные композиции для лечения пародонтита и способ применения
JP2024540454A (ja) * 2021-11-17 2024-10-31 ナード バイオ エルエルシー リアルタイムの細胞薬剤ターゲットエンゲージメントのためのシステムおよび方法
CN114469863B (zh) * 2021-11-26 2023-09-26 南方医科大学南方医院 甾醇脂质体作为牙髓和牙本质药物传递系统的应用
CN116474096A (zh) * 2022-01-14 2023-07-25 中山大学附属口腔医院 靶向牙龈卟啉单胞菌RgpB在结直肠癌的治疗及预防中的应用
CA3250494A1 (en) * 2022-04-26 2023-11-02 Keystone Bio Inc FORMULATION FOR ANTIGEN-BINDING MOLECULES THAT BIND TO PORPHYROMONAS GINGIVALIS
EP4587050A1 (en) * 2022-09-16 2025-07-23 Xiaoju Shi Antibodies and method of use for p. gingivalis
TW202517779A (zh) 2023-07-19 2025-05-01 法商賽諾菲公司 牙齦卟啉單胞菌抗原性構築體
CN116751292B (zh) * 2023-07-31 2024-05-14 河南大学 牙龈卟啉单胞菌Mfa1单克隆抗体及其应用
CN119424610A (zh) * 2024-12-05 2025-02-14 重庆师范大学 具备抗衰老活性的重组蛋白制剂及其制备方法、应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6129917A (en) * 1996-03-22 2000-10-10 The University Of Georgia Research Foundation, Inc. Immunogenic compositions comprising porphyromonas gingivalis proteins and/or peptides and methods
AUPN901296A0 (en) * 1996-03-29 1996-04-26 University Of Melbourne, The Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis
EP1681350A3 (en) * 1997-12-10 2007-07-18 Csl Limited Porphorymonas gingivalis polypeptides and polynucleotides
JP2003192616A (ja) * 2001-12-27 2003-07-09 Univ Nihon 歯周病用dnaワクチン
JP2003286191A (ja) * 2002-03-27 2003-10-07 Univ Nihon 歯周病用粘膜免疫ワクチン
US20070036734A1 (en) * 2003-03-17 2007-02-15 Kirin Beer Kabushiki Kaisha Therapeutic agent for periodontal disease
JP2005179301A (ja) * 2003-12-22 2005-07-07 Univ Nihon 歯周病用経皮免疫ワクチン
AU2007264402B2 (en) 2006-06-27 2012-09-20 Oral Health Australia Pty Ltd Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease
US20100297179A1 (en) * 2007-07-12 2010-11-25 Stuart Geoffrey Dashper Immunology Treatment for Biofilms

Also Published As

Publication number Publication date
JP2015178533A (ja) 2015-10-08
CN102712693A (zh) 2012-10-03
WO2011014947A1 (en) 2011-02-10
CA2769231A1 (en) 2011-02-10
JP2013501007A (ja) 2013-01-10
ZA201200799B (en) 2013-06-26
AR085167A1 (es) 2013-09-18
RU2012107993A (ru) 2013-09-10
AU2010281313A1 (en) 2012-03-08
EP2462160A4 (en) 2013-04-24
KR20120050469A (ko) 2012-05-18
AU2010281313B2 (en) 2015-09-03
EP2462160A1 (en) 2012-06-13
US20120156211A1 (en) 2012-06-21
BR112012002429A2 (pt) 2016-11-08
IL217861A0 (en) 2012-03-29
MX2012001495A (es) 2012-08-03
US9366673B2 (en) 2016-06-14

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