KR20100020465A - 야누스 키나제의 티로신 키나제 활성의 억제제로서의 퀴녹살린 유도체 - Google Patents

야누스 키나제의 티로신 키나제 활성의 억제제로서의 퀴녹살린 유도체 Download PDF

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KR20100020465A
KR20100020465A KR1020097025493A KR20097025493A KR20100020465A KR 20100020465 A KR20100020465 A KR 20100020465A KR 1020097025493 A KR1020097025493 A KR 1020097025493A KR 20097025493 A KR20097025493 A KR 20097025493A KR 20100020465 A KR20100020465 A KR 20100020465A
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phenyl
methyl
bromo
preparation
tfa
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Korean (ko)
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마르크 게르스파처
파스칼 퓌레
에릭 반그레베링게
캐롤 피소 솔데르만
크리스토프 가울
필립 홀처
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노파르티스 아게
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
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    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
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  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020097025493A 2007-06-08 2008-06-06 야누스 키나제의 티로신 키나제 활성의 억제제로서의 퀴녹살린 유도체 Withdrawn KR20100020465A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP07109880 2007-06-08
EP07109880.0 2007-06-08
EP07150266 2007-12-20
EP07150266.0 2007-12-20

Publications (1)

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KR20100020465A true KR20100020465A (ko) 2010-02-22

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KR1020097025493A Withdrawn KR20100020465A (ko) 2007-06-08 2008-06-06 야누스 키나제의 티로신 키나제 활성의 억제제로서의 퀴녹살린 유도체

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US (1) US8193189B2 (https=)
EP (1) EP2155201B1 (https=)
JP (1) JP5574957B2 (https=)
KR (1) KR20100020465A (https=)
CN (1) CN101678020B (https=)
AR (1) AR066879A1 (https=)
AU (1) AU2008258486B2 (https=)
BR (1) BRPI0812893A2 (https=)
CA (1) CA2690288A1 (https=)
CL (1) CL2008001659A1 (https=)
EA (1) EA200901608A1 (https=)
ES (1) ES2392570T3 (https=)
MX (1) MX2009013218A (https=)
PA (1) PA8783501A1 (https=)
TW (1) TW200904814A (https=)
UY (1) UY31126A1 (https=)
WO (1) WO2008148867A2 (https=)

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CA2690288A1 (en) 2008-12-11
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CN101678020B (zh) 2012-08-15
PA8783501A1 (es) 2009-01-23
EP2155201B1 (en) 2012-08-01
AU2008258486A1 (en) 2008-12-11
BRPI0812893A2 (pt) 2014-12-09
WO2008148867A3 (en) 2009-04-09
TW200904814A (en) 2009-02-01
EP2155201A2 (en) 2010-02-24
JP5574957B2 (ja) 2014-08-20
EA200901608A1 (ru) 2010-06-30
AR066879A1 (es) 2009-09-16
WO2008148867A2 (en) 2008-12-11
CN101678020A (zh) 2010-03-24
ES2392570T3 (es) 2012-12-11
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CL2008001659A1 (es) 2009-02-20

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