KR20070084069A - Tnfr1에 대한 단일 도메인 항체 및 이의 사용 방법 - Google Patents
Tnfr1에 대한 단일 도메인 항체 및 이의 사용 방법 Download PDFInfo
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- KR20070084069A KR20070084069A KR1020077010453A KR20077010453A KR20070084069A KR 20070084069 A KR20070084069 A KR 20070084069A KR 1020077010453 A KR1020077010453 A KR 1020077010453A KR 20077010453 A KR20077010453 A KR 20077010453A KR 20070084069 A KR20070084069 A KR 20070084069A
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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| GBPCT/GB04/04253 | 2004-10-08 | ||
| US10/985,847 US20060002935A1 (en) | 2002-06-28 | 2004-11-10 | Tumor Necrosis Factor Receptor 1 antagonists and methods of use therefor |
| US10/985,847 | 2004-11-10 |
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| US9321832B2 (en) | 2002-06-28 | 2016-04-26 | Domantis Limited | Ligand |
| AU2005250216B2 (en) | 2004-06-01 | 2009-12-10 | Domantis Limited | Bispecific fusion antibodies with enhanced serum half-life |
| EP1802333A2 (en) * | 2004-09-13 | 2007-07-04 | Arrowsmith Technologies LLP | Antibody buffering of a ligand in vivo |
| BRPI0518762A2 (pt) * | 2004-12-02 | 2008-12-09 | Domantis Ltd | fusço de droga, conjugado de droga, Ácido nucleico recombinante ou isolado, construÇço de Ácido nucleico, cÉlula hospedeira, mÉtodo para produzir a fusço de droga, composiÇço farmacÊutica, mÉtodo para tratamento de um indivÍduo tendo uma doenÇa inflamatària, uso de um conjugado de droga ou fusço de droga, e, composiÇço de droga |
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| US9249407B2 (en) | 2006-02-03 | 2016-02-02 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| US20150038413A1 (en) | 2006-02-03 | 2015-02-05 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US10351615B2 (en) | 2006-02-03 | 2019-07-16 | Opko Biologics Ltd. | Methods of treatment with long-acting growth hormone |
| US8946155B2 (en) | 2006-02-03 | 2015-02-03 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
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| US12203113B2 (en) | 2009-07-09 | 2025-01-21 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| US9663778B2 (en) | 2009-07-09 | 2017-05-30 | OPKO Biologies Ltd. | Long-acting coagulation factors and methods of producing same |
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| RU2664473C2 (ru) * | 2012-03-16 | 2018-08-17 | Регенерон Фармасьютикалз, Инк. | ОТЛИЧНЫЕ ОТ ЧЕЛОВЕКА ЖИВОТНЫЕ, ЭКСПРЕССИРУЮЩИЕ ЧУВСТВИТЕЛЬНЫЕ К pН ПОСЛЕДОВАТЕЛЬНОСТИ ИММУНОГЛОБУЛИНОВ |
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| CN112661863A (zh) | 2012-11-20 | 2021-04-16 | 奥普科生物制品有限公司 | 通过连接至促性腺激素羧基端肽来增加多肽的流体动力学体积的方法 |
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| EP2938740B1 (en) | 2012-12-27 | 2022-04-20 | NGM Biopharmaceuticals, Inc. | Chimeric fgf19 peptides for use in treating bile acid disorders |
| RU2560699C2 (ru) * | 2013-08-02 | 2015-08-20 | федеральное государственное автономное образовательное учреждение высшего профессионального образования "Национальный исследовательский ядерный университет МИФИ" (НИЯУ МИФИ) | Способ создания наноразмерной диагностической метки на основе конъюгатов наночастиц и однодоменных антител |
| US20150158926A1 (en) | 2013-10-21 | 2015-06-11 | Opko Biologics, Ltd. | Long-acting polypeptides and methods of producing and administering same |
| SG10201802098UA (en) | 2014-07-30 | 2018-04-27 | Ngm Biopharmaceuticals Inc | Compositions and methods of use for treating metabolic disorders |
| IL251834B2 (en) | 2014-10-23 | 2023-09-01 | Ngm Biopharmaceuticals Inc | Pharmaceutical compositions containing peptide variants and methods of using them |
| CN115043945A (zh) | 2014-10-31 | 2022-09-13 | Ngm生物制药有限公司 | 用于治疗代谢病症的组合物和方法 |
| TWI746427B (zh) | 2014-12-10 | 2021-11-21 | 以色列商歐科生物製品有限公司 | 製造長效ctp修飾的多肽之方法 |
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- 2005-11-10 EP EP05801585A patent/EP1814584A2/en not_active Ceased
- 2005-11-10 AU AU2005303584A patent/AU2005303584A1/en not_active Abandoned
- 2005-11-10 KR KR1020077012946A patent/KR20070089930A/ko not_active Withdrawn
- 2005-11-10 CA CA002587206A patent/CA2587206A1/en not_active Abandoned
- 2005-11-10 BR BRPI0517569-0A patent/BRPI0517569A/pt not_active IP Right Cessation
- 2005-11-10 CN CNA2005800461844A patent/CN101098712A/zh active Pending
- 2005-11-10 WO PCT/GB2005/004319 patent/WO2006051288A2/en not_active Ceased
- 2005-11-10 JP JP2007540709A patent/JP2008519813A/ja active Pending
- 2005-11-10 EP EP11161978A patent/EP2420251A3/en not_active Withdrawn
-
2007
- 2007-04-03 NO NO20071788A patent/NO20071788L/no not_active Application Discontinuation
- 2007-05-07 MA MA29876A patent/MA29427B1/fr unknown
- 2007-05-16 NO NO20072475A patent/NO20072475L/no not_active Application Discontinuation
- 2007-06-06 MA MA29969A patent/MA29221B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2420251A3 (en) | 2013-03-13 |
| MA29221B1 (fr) | 2008-02-01 |
| CA2587206A1 (en) | 2006-05-18 |
| NO20071788L (no) | 2007-07-06 |
| EP2420251A2 (en) | 2012-02-22 |
| CN101098712A (zh) | 2008-01-02 |
| CN101724071A (zh) | 2010-06-09 |
| JP2008519813A (ja) | 2008-06-12 |
| RU2007112509A (ru) | 2008-11-27 |
| WO2006051288A3 (en) | 2006-08-17 |
| RU2401842C2 (ru) | 2010-10-20 |
| MA29427B1 (fr) | 2008-05-02 |
| AU2005303584A1 (en) | 2006-05-18 |
| WO2006051288A2 (en) | 2006-05-18 |
| BRPI0517569A (pt) | 2008-10-14 |
| NO20072475L (no) | 2007-08-06 |
| EP1814584A2 (en) | 2007-08-08 |
| KR20070089930A (ko) | 2007-09-04 |
| RU2007117196A (ru) | 2008-12-20 |
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