ATE234918T1 - Monoklonale antikörper gegen lösliche tnf-alpha rezeptoren p55 und p75 als auch gegen tnf-alpha und dessen analogen - Google Patents
Monoklonale antikörper gegen lösliche tnf-alpha rezeptoren p55 und p75 als auch gegen tnf-alpha und dessen analogenInfo
- Publication number
- ATE234918T1 ATE234918T1 AT96926042T AT96926042T ATE234918T1 AT E234918 T1 ATE234918 T1 AT E234918T1 AT 96926042 T AT96926042 T AT 96926042T AT 96926042 T AT96926042 T AT 96926042T AT E234918 T1 ATE234918 T1 AT E234918T1
- Authority
- AT
- Austria
- Prior art keywords
- alpha
- tnf
- monoclonal antibodies
- receptors
- analogues
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SI9500249A SI9500249B (sl) | 1995-08-04 | 1995-08-04 | Monoklonska protitelesa proti topnima TNF-alfa receptorjema p55 in p75 ter TNF-alfa in njegovim analogom |
SI9600206A SI9600206B (sl) | 1996-06-28 | 1996-06-28 | Monoklonska protitelesa proti topnima TNF-alfa receptorjema p55 in p75 ter TNF-alfa in njegovim analogom |
PCT/SI1996/000018 WO1997006251A1 (en) | 1995-08-04 | 1996-07-31 | MONOCLONAL ANTIBODIES AGAINST SOLUBLE TNF-α RECEPTORS p55 and p75 AS WELL AS AGAINST TNF-α AND ITS ANALOGUES |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE234918T1 true ATE234918T1 (de) | 2003-04-15 |
Family
ID=26665256
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96926042T ATE234918T1 (de) | 1995-08-04 | 1996-07-31 | Monoklonale antikörper gegen lösliche tnf-alpha rezeptoren p55 und p75 als auch gegen tnf-alpha und dessen analogen |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0846169B1 (de) |
AT (1) | ATE234918T1 (de) |
AU (1) | AU703091B2 (de) |
DE (1) | DE69626829T2 (de) |
WO (1) | WO1997006251A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7427492B1 (en) | 1995-06-05 | 2008-09-23 | Human Genome Sciences, Inc. | Polynucleotides encoding human tumor necrosis factor receptor-like2 |
WO2000020578A1 (en) | 1998-10-06 | 2000-04-13 | The Walter And Eliza Hall Institute Of Medical Research | A method of modulating cell survival and reagents useful for same |
US7112409B2 (en) | 1999-01-29 | 2006-09-26 | Center For Molecular Medicine And Immunology | Method of determining cytokine dosage for myelosuppressive state |
US6649352B1 (en) | 1999-01-29 | 2003-11-18 | Center For Molecular Medicine And Immunology | Method of evaluating myelosuppressive state |
WO2000056405A2 (en) * | 1999-03-22 | 2000-09-28 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor-like 2 |
US9028822B2 (en) | 2002-06-28 | 2015-05-12 | Domantis Limited | Antagonists against TNFR1 and methods of use therefor |
US20040033228A1 (en) | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
SI21373A (sl) * | 2002-11-22 | 2004-06-30 | LEK farmacevtska družba d.d. | Metoda za moduliranje biološke aktivnosti proteinov |
RU2401842C2 (ru) * | 2004-10-08 | 2010-10-20 | Домантис Лимитед | Антагонисты и способы их применения |
WO2007060411A1 (en) * | 2005-11-24 | 2007-05-31 | Ucb Pharma S.A. | Anti-tnf alpha antibodies which selectively inhibit tnf alpha signalling through the p55r |
WO2014008480A2 (en) † | 2012-07-06 | 2014-01-09 | Biogen Idec Ma Inc. | Cell line expressing single chain factor viii polypeptides and uses thereof |
US10988543B2 (en) | 2015-11-11 | 2021-04-27 | Opi Vi—Ip Holdco Llc | Humanized anti-tumor necrosis factor alpha receptor 2 (anti-TNFR2) antibodies and methods of use thereof to elicit an immune response against a tumor |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4870163A (en) * | 1985-08-29 | 1989-09-26 | New York Blood Center, Inc. | Preparation of pure human tumor necrosis factor and hybridomas producing monoclonal antibodies to human tumor necrosis factor |
DE3888224T2 (de) * | 1987-04-24 | 1994-07-21 | Teijin Ltd | Bestimmung vom Tumornekrosefaktor; monoklonaler Antikörper und Zusammensetzung. |
DE3823804A1 (de) * | 1988-07-14 | 1990-01-18 | Basf Ag | Neutralisation der in vitro und in vivo toxischen eigenschaften von tnf-(alpha) durch monoklonale antikoerper und den davon abgeleiteten fragmenten |
GB9028123D0 (en) * | 1990-12-28 | 1991-02-13 | Erba Carlo Spa | Monoclonal antibodies against human tumor necrosis factor alpha |
DE59209888D1 (de) * | 1991-06-19 | 2001-02-22 | Boehringer Ingelheim Int | Monoklonale antikörper gegen das humane tnf-bindende protein i (tnf-bp i) |
-
1996
- 1996-07-31 AT AT96926042T patent/ATE234918T1/de not_active IP Right Cessation
- 1996-07-31 EP EP96926042A patent/EP0846169B1/de not_active Expired - Lifetime
- 1996-07-31 WO PCT/SI1996/000018 patent/WO1997006251A1/en active IP Right Grant
- 1996-07-31 DE DE69626829T patent/DE69626829T2/de not_active Expired - Lifetime
- 1996-07-31 AU AU66345/96A patent/AU703091B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
EP0846169A1 (de) | 1998-06-10 |
DE69626829T2 (de) | 2004-03-18 |
EP0846169B1 (de) | 2003-03-19 |
DE69626829D1 (de) | 2003-04-24 |
AU6634596A (en) | 1997-03-05 |
AU703091B2 (en) | 1999-03-18 |
WO1997006251A1 (en) | 1997-02-20 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |