KR20050044689A - 혈액 산물을 제조하기 위한 방법 및 시스템 - Google Patents
혈액 산물을 제조하기 위한 방법 및 시스템 Download PDFInfo
- Publication number
- KR20050044689A KR20050044689A KR1020047008577A KR20047008577A KR20050044689A KR 20050044689 A KR20050044689 A KR 20050044689A KR 1020047008577 A KR1020047008577 A KR 1020047008577A KR 20047008577 A KR20047008577 A KR 20047008577A KR 20050044689 A KR20050044689 A KR 20050044689A
- Authority
- KR
- South Korea
- Prior art keywords
- container
- plasma
- platelets
- storage medium
- synthetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 238000000034 method Methods 0.000 title claims abstract description 64
- 239000010836 blood and blood product Substances 0.000 title claims abstract description 21
- 229940125691 blood product Drugs 0.000 title claims abstract description 21
- 244000052769 pathogen Species 0.000 claims abstract description 54
- 230000001717 pathogenic effect Effects 0.000 claims abstract description 48
- 230000002779 inactivation Effects 0.000 claims abstract description 44
- 239000012503 blood component Substances 0.000 claims abstract description 40
- 210000001772 blood platelet Anatomy 0.000 claims description 138
- 238000003860 storage Methods 0.000 claims description 67
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 26
- 239000012530 fluid Substances 0.000 claims description 24
- 238000011282 treatment Methods 0.000 claims description 24
- 210000003743 erythrocyte Anatomy 0.000 claims description 23
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims description 18
- 239000001488 sodium phosphate Substances 0.000 claims description 17
- 229910000162 sodium phosphate Inorganic materials 0.000 claims description 17
- 210000004369 blood Anatomy 0.000 claims description 16
- 239000008280 blood Substances 0.000 claims description 16
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 15
- 239000001509 sodium citrate Substances 0.000 claims description 14
- 239000011780 sodium chloride Substances 0.000 claims description 13
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 claims description 12
- 238000004891 communication Methods 0.000 claims description 12
- 239000001632 sodium acetate Substances 0.000 claims description 12
- 235000017281 sodium acetate Nutrition 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 11
- 238000011287 therapeutic dose Methods 0.000 claims description 10
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 239000007864 aqueous solution Substances 0.000 claims 2
- 239000000243 solution Substances 0.000 claims 1
- 238000012545 processing Methods 0.000 abstract description 11
- 210000002381 plasma Anatomy 0.000 description 77
- 239000000543 intermediate Substances 0.000 description 50
- 150000001875 compounds Chemical class 0.000 description 18
- 239000000306 component Substances 0.000 description 17
- 238000000926 separation method Methods 0.000 description 11
- 230000036541 health Effects 0.000 description 8
- 239000000463 material Substances 0.000 description 8
- 239000000203 mixture Substances 0.000 description 7
- 238000005119 centrifugation Methods 0.000 description 6
- 239000004615 ingredient Substances 0.000 description 6
- 230000000415 inactivating effect Effects 0.000 description 5
- 238000005070 sampling Methods 0.000 description 5
- 239000012815 thermoplastic material Substances 0.000 description 5
- 239000003634 thrombocyte concentrate Substances 0.000 description 5
- 229920012485 Plasticized Polyvinyl chloride Polymers 0.000 description 4
- 230000007774 longterm Effects 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- -1 styrene ethylene butylene styrene Chemical class 0.000 description 4
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 description 3
- 229930024421 Adenine Natural products 0.000 description 3
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 3
- 229930195725 Mannitol Natural products 0.000 description 3
- 229960000643 adenine Drugs 0.000 description 3
- QKSKPIVNLNLAAV-UHFFFAOYSA-N bis(2-chloroethyl) sulfide Chemical compound ClCCSCCCl QKSKPIVNLNLAAV-UHFFFAOYSA-N 0.000 description 3
- 239000000594 mannitol Substances 0.000 description 3
- 235000010355 mannitol Nutrition 0.000 description 3
- 239000004800 polyvinyl chloride Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 229920001400 block copolymer Polymers 0.000 description 2
- DQXBYHZEEUGOBF-UHFFFAOYSA-N but-3-enoic acid;ethene Chemical compound C=C.OC(=O)CC=C DQXBYHZEEUGOBF-UHFFFAOYSA-N 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000003750 conditioning effect Effects 0.000 description 2
- 239000008121 dextrose Substances 0.000 description 2
- 238000010894 electron beam technology Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000005038 ethylene vinyl acetate Substances 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 239000012533 medium component Substances 0.000 description 2
- 229960000907 methylthioninium chloride Drugs 0.000 description 2
- 229940021317 other blood product in atc Drugs 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 239000008279 sol Substances 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 229920001862 ultra low molecular weight polyethylene Polymers 0.000 description 2
- 230000035899 viability Effects 0.000 description 2
- KJCVRFUGPWSIIH-UHFFFAOYSA-N 1-naphthol Chemical compound C1=CC=C2C(O)=CC=CC2=C1 KJCVRFUGPWSIIH-UHFFFAOYSA-N 0.000 description 1
- RBTBFTRPCNLSDE-UHFFFAOYSA-N 3,7-bis(dimethylamino)phenothiazin-5-ium Chemical compound C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 RBTBFTRPCNLSDE-UHFFFAOYSA-N 0.000 description 1
- BVPWJMCABCPUQY-UHFFFAOYSA-N 4-amino-5-chloro-2-methoxy-N-[1-(phenylmethyl)-4-piperidinyl]benzamide Chemical compound COC1=CC(N)=C(Cl)C=C1C(=O)NC1CCN(CC=2C=CC=CC=2)CC1 BVPWJMCABCPUQY-UHFFFAOYSA-N 0.000 description 1
- 241000219198 Brassica Species 0.000 description 1
- 235000003351 Brassica cretica Nutrition 0.000 description 1
- 235000003343 Brassica rupestris Nutrition 0.000 description 1
- 206010067787 Coagulation factor deficiency Diseases 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- 239000004803 Di-2ethylhexylphthalate Substances 0.000 description 1
- 229920002633 Kraton (polymer) Polymers 0.000 description 1
- VAYOSLLFUXYJDT-RDTXWAMCSA-N Lysergic acid diethylamide Chemical compound C1=CC(C=2[C@H](N(C)C[C@@H](C=2)C(=O)N(CC)CC)C2)=C3C2=CNC3=C1 VAYOSLLFUXYJDT-RDTXWAMCSA-N 0.000 description 1
- 229930192627 Naphthoquinone Natural products 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 241000220317 Rosa Species 0.000 description 1
- 229930003448 Vitamin K Natural products 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 125000004559 acridin-9-yl group Chemical group C1=CC=CC2=NC3=CC=CC=C3C(=C12)* 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 150000008064 anhydrides Chemical class 0.000 description 1
- 238000002617 apheresis Methods 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- BJQHLKABXJIVAM-UHFFFAOYSA-N bis(2-ethylhexyl) phthalate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC BJQHLKABXJIVAM-UHFFFAOYSA-N 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 150000001860 citric acid derivatives Chemical class 0.000 description 1
- 208000014763 coagulation protein disease Diseases 0.000 description 1
- 239000012611 container material Substances 0.000 description 1
- 238000010924 continuous production Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- IPZJQDSFZGZEOY-UHFFFAOYSA-N dimethylmethylene Chemical group C[C]C IPZJQDSFZGZEOY-UHFFFAOYSA-N 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000012953 feeding on blood of other organism Effects 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 235000010460 mustard Nutrition 0.000 description 1
- 150000002791 naphthoquinones Chemical class 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 125000001484 phenothiazinyl group Chemical class C1(=CC=CC=2SC3=CC=CC=C3NC12)* 0.000 description 1
- 239000003504 photosensitizing agent Substances 0.000 description 1
- IEQIEDJGQAUEQZ-UHFFFAOYSA-N phthalocyanine Chemical class N1C(N=C2C3=CC=CC=C3C(N=C3C4=CC=CC=C4C(=N4)N3)=N2)=C(C=CC=C2)C2=C1N=C1C2=CC=CC=C2C4=N1 IEQIEDJGQAUEQZ-UHFFFAOYSA-N 0.000 description 1
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 1
- 230000004962 physiological condition Effects 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 235000019192 riboflavin Nutrition 0.000 description 1
- 239000002151 riboflavin Substances 0.000 description 1
- AYRVGWHSXIMRAB-UHFFFAOYSA-M sodium acetate trihydrate Chemical compound O.O.O.[Na+].CC([O-])=O AYRVGWHSXIMRAB-UHFFFAOYSA-M 0.000 description 1
- 229960000999 sodium citrate dihydrate Drugs 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 229940066767 systemic antihistamines phenothiazine derivative Drugs 0.000 description 1
- DCTZJRUXIXPDJP-UHFFFAOYSA-N trihexyl 2-hydroxy-4-oxoheptane-1,2,3-tricarboxylate Chemical compound CCCCCCOC(=O)CC(O)(C(=O)OCCCCCC)C(C(=O)CCC)C(=O)OCCCCCC DCTZJRUXIXPDJP-UHFFFAOYSA-N 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- YNIRKEZIDLCCMC-UHFFFAOYSA-K trisodium;phosphate;hydrate Chemical compound [OH-].[Na+].[Na+].[Na+].OP([O-])([O-])=O YNIRKEZIDLCCMC-UHFFFAOYSA-K 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
- 229940046010 vitamin k Drugs 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
- A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- External Artificial Organs (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/004,696 US6936413B1 (en) | 2001-12-05 | 2001-12-05 | Methods and systems for preparing blood products |
| US10/004,696 | 2001-12-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20050044689A true KR20050044689A (ko) | 2005-05-12 |
Family
ID=21712067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020047008577A Ceased KR20050044689A (ko) | 2001-12-05 | 2002-11-22 | 혈액 산물을 제조하기 위한 방법 및 시스템 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6936413B1 (enExample) |
| EP (1) | EP1450716B1 (enExample) |
| JP (1) | JP2005511197A (enExample) |
| KR (1) | KR20050044689A (enExample) |
| CN (1) | CN100500231C (enExample) |
| AU (2) | AU2002352877B2 (enExample) |
| CA (1) | CA2469364C (enExample) |
| MX (1) | MXPA04005457A (enExample) |
| WO (1) | WO2003049634A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100765249B1 (ko) * | 2006-03-23 | 2007-10-09 | 송영완 | 농축혈소판 겔 형성 트레이 |
| KR20160028401A (ko) * | 2014-09-03 | 2016-03-11 | 썬 파마슈티컬 인더스트리스 리미티드 | 관류 투여 형태 |
| US12138419B2 (en) | 2016-02-09 | 2024-11-12 | Sun Pharmaceutical Industries Ltd. | Perfusion system |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6936413B1 (en) * | 2001-12-05 | 2005-08-30 | Baxter International Inc. | Methods and systems for preparing blood products |
| EP2208502B1 (en) * | 2001-12-10 | 2019-05-08 | Terumo BCT, Inc. | Disposable assembly for an apheresis system |
| JP2005523337A (ja) * | 2002-04-24 | 2005-08-04 | ガンブロ インコーポレーテッド | 病原体が減少する血液および血液構成成分のプロセスの間でのアデニンの除去 |
| US20070243608A1 (en) * | 2006-04-14 | 2007-10-18 | Board Of Regents, The University Of Texas System | Platelet bioreactor |
| US8835104B2 (en) * | 2007-12-20 | 2014-09-16 | Fenwal, Inc. | Medium and methods for the storage of platelets |
| US8968992B2 (en) * | 2008-03-21 | 2015-03-03 | Fenwal, Inc. | Red blood cell storage medium for extended storage |
| US8871434B2 (en) * | 2008-03-21 | 2014-10-28 | Fenwal, Inc. | Red blood cell storage medium for extended storage |
| WO2011049709A1 (en) | 2009-10-23 | 2011-04-28 | Fenwal, Inc. | Methods and systems for providing red blood cell products with reduced plasma |
| US9164079B2 (en) * | 2011-03-17 | 2015-10-20 | Greyledge Technologies Llc | Systems for autologous biological therapeutics |
| WO2012139017A1 (en) | 2011-04-07 | 2012-10-11 | Fenwal, Inc. | Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates |
| EP2704760B1 (en) * | 2011-05-03 | 2017-09-20 | Fenwal, Inc. | Platelet resuspension method and apparatus |
| US20140086892A1 (en) * | 2011-09-19 | 2014-03-27 | FENWAL, INC. a Delaware Corporation | Red blood cell products and the storage of red blood cells in non-pvc containers |
| CN103028154B (zh) * | 2011-12-14 | 2015-10-07 | 南京双威生物医学科技有限公司 | 一种血小板分离袋及手工分离血小板的方法 |
| WO2014051537A1 (en) * | 2012-09-25 | 2014-04-03 | Biovec Transfusion, Llc | Device and method for removing additives in the blood products |
| AU2016283389B2 (en) | 2015-06-26 | 2022-09-15 | Cerus Corporation | Cryoprecipitate compositions and methods of preparation thereof |
| CA3003097A1 (en) | 2015-10-23 | 2017-04-27 | Cerus Corporation | Plasma compositions and methods of use thereof |
| EP3399986B1 (en) * | 2016-01-07 | 2023-02-22 | Cerus Corporation | Systems and methods for preparation of platelets |
| EP3300748B1 (en) * | 2016-09-21 | 2021-11-03 | Fenwal, Inc. | Disposable fluid circuits for extracorporeal photopheresis with integrated source of photoactive agent |
| US11235090B2 (en) | 2017-03-03 | 2022-02-01 | Cerus Corporation | Kits and methods for preparing pathogen-inactivated platelet compositions |
| JP7495360B2 (ja) * | 2019-02-15 | 2024-06-04 | テルモ株式会社 | バッグセット |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4322298A (en) * | 1981-06-01 | 1982-03-30 | Advanced Blood Component Technology, Inc. | Centrifugal cell separator, and method of use thereof |
| US4670013A (en) | 1982-12-27 | 1987-06-02 | Miles Laboratories, Inc. | Container for blood and blood components |
| IT1217938B (it) * | 1988-06-28 | 1990-03-30 | Girolamo Sirchia | Procedimento per la preparazione e la conservazione di concentrati eritrocitari e piastrinici |
| US5089146A (en) | 1990-02-12 | 1992-02-18 | Miles Inc. | Pre-storage filtration of platelets |
| SE9001271D0 (sv) | 1990-04-06 | 1990-04-06 | Eric Westberg | Blodpaase foer anvaendning vid separation av blod i komponenter |
| JP3182145B2 (ja) * | 1990-04-16 | 2001-07-03 | 日本赤十字社 | 血小板保存液 |
| JP2838725B2 (ja) | 1990-05-02 | 1998-12-16 | テルモ株式会社 | 血液採取器具 |
| JP2980663B2 (ja) | 1990-10-05 | 1999-11-22 | テルモ株式会社 | バッグ連結体 |
| DE9102709U1 (de) | 1991-03-07 | 1991-05-23 | Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Oldenburg und Bremen Gemeinnützige GmbH, 3257 Springe | Blutbeutelanordnung |
| JPH06500042A (ja) | 1991-05-08 | 1994-01-06 | バクスター、インターナショナル、インコーポレイテッド | 微生物不含長期間貯蔵のため赤血球製品を処理する方法 |
| US5269946A (en) * | 1991-05-22 | 1993-12-14 | Baxter Healthcare Corporation | Systems and methods for removing undesired matter from blood cells |
| US5459030A (en) * | 1992-03-02 | 1995-10-17 | Steritech, Inc. | Synthetic media compositions for inactivating bacteria and viruses in blood preparations with 8-methoxypsoralen |
| US5618662A (en) | 1992-03-02 | 1997-04-08 | Cerus Corporation | Intravenous administration of psoralen |
| WO1996014740A1 (en) | 1992-03-02 | 1996-05-23 | Cerus Corporation | Synthetic media for blood components |
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- 2002-11-22 CN CNB028242882A patent/CN100500231C/zh not_active Expired - Lifetime
- 2002-11-22 MX MXPA04005457A patent/MXPA04005457A/es active IP Right Grant
- 2002-11-22 KR KR1020047008577A patent/KR20050044689A/ko not_active Ceased
- 2002-11-22 CA CA2469364A patent/CA2469364C/en not_active Expired - Lifetime
- 2002-11-22 AU AU2002352877A patent/AU2002352877B2/en not_active Expired
- 2002-11-22 JP JP2003550685A patent/JP2005511197A/ja active Pending
- 2002-11-22 WO PCT/US2002/037554 patent/WO2003049634A1/en not_active Ceased
- 2002-11-22 EP EP02789836.0A patent/EP1450716B1/en not_active Expired - Lifetime
-
2005
- 2005-07-01 US US11/173,214 patent/US20050256443A1/en not_active Abandoned
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2008
- 2008-06-19 AU AU2008202709A patent/AU2008202709B2/en not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100765249B1 (ko) * | 2006-03-23 | 2007-10-09 | 송영완 | 농축혈소판 겔 형성 트레이 |
| KR20160028401A (ko) * | 2014-09-03 | 2016-03-11 | 썬 파마슈티컬 인더스트리스 리미티드 | 관류 투여 형태 |
| US11793719B2 (en) | 2014-09-03 | 2023-10-24 | Sun Pharmaceutical Industries Limited | Perfusion dosage form |
| US12138419B2 (en) | 2016-02-09 | 2024-11-12 | Sun Pharmaceutical Industries Ltd. | Perfusion system |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005511197A (ja) | 2005-04-28 |
| MXPA04005457A (es) | 2004-10-11 |
| CN1599581A (zh) | 2005-03-23 |
| AU2002352877A1 (en) | 2003-06-23 |
| AU2008202709B2 (en) | 2010-06-17 |
| US20050256443A1 (en) | 2005-11-17 |
| EP1450716B1 (en) | 2016-04-06 |
| EP1450716A4 (en) | 2010-11-10 |
| CA2469364C (en) | 2013-04-09 |
| CN100500231C (zh) | 2009-06-17 |
| US6936413B1 (en) | 2005-08-30 |
| AU2008202709A1 (en) | 2008-07-17 |
| WO2003049634A1 (en) | 2003-06-19 |
| AU2002352877B2 (en) | 2008-03-20 |
| EP1450716A1 (en) | 2004-09-01 |
| CA2469364A1 (en) | 2003-06-19 |
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