AU2002352877B2 - Methods and systems for preparing blood products - Google Patents
Methods and systems for preparing blood products Download PDFInfo
- Publication number
- AU2002352877B2 AU2002352877B2 AU2002352877A AU2002352877A AU2002352877B2 AU 2002352877 B2 AU2002352877 B2 AU 2002352877B2 AU 2002352877 A AU2002352877 A AU 2002352877A AU 2002352877 A AU2002352877 A AU 2002352877A AU 2002352877 B2 AU2002352877 B2 AU 2002352877B2
- Authority
- AU
- Australia
- Prior art keywords
- container
- platelets
- plasma
- approximately
- interim
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title claims description 63
- 239000010836 blood and blood product Substances 0.000 title claims description 21
- 229940125691 blood product Drugs 0.000 title claims description 21
- 238000003860 storage Methods 0.000 claims description 57
- 244000052769 pathogen Species 0.000 claims description 54
- 230000001717 pathogenic effect Effects 0.000 claims description 49
- 230000002779 inactivation Effects 0.000 claims description 46
- 239000012503 blood component Substances 0.000 claims description 35
- 238000002617 apheresis Methods 0.000 claims description 28
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 20
- 239000012530 fluid Substances 0.000 claims description 18
- 238000011282 treatment Methods 0.000 claims description 17
- 239000000306 component Substances 0.000 claims description 13
- 238000012545 processing Methods 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 11
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 11
- 239000011780 sodium chloride Substances 0.000 claims description 10
- 239000001509 sodium citrate Substances 0.000 claims description 10
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims description 10
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 claims description 9
- 235000017281 sodium acetate Nutrition 0.000 claims description 9
- 239000001632 sodium acetate Substances 0.000 claims description 9
- 229910000162 sodium phosphate Inorganic materials 0.000 claims description 9
- 239000001488 sodium phosphate Substances 0.000 claims description 9
- 238000012546 transfer Methods 0.000 claims description 9
- 238000004891 communication Methods 0.000 claims description 7
- 239000006228 supernatant Substances 0.000 claims 6
- 210000001772 blood platelet Anatomy 0.000 description 118
- 210000002381 plasma Anatomy 0.000 description 77
- 210000003743 erythrocyte Anatomy 0.000 description 18
- 150000001875 compounds Chemical class 0.000 description 16
- 210000004369 blood Anatomy 0.000 description 13
- 239000008280 blood Substances 0.000 description 13
- 238000000926 separation method Methods 0.000 description 12
- 238000011287 therapeutic dose Methods 0.000 description 10
- 239000000463 material Substances 0.000 description 9
- -1 photoactivated psoralen compound Chemical class 0.000 description 9
- ZCCUUQDIBDJBTK-UHFFFAOYSA-N furocoumarin Natural products C1=C2OC(=O)C=CC2=CC2=C1OC=C2 ZCCUUQDIBDJBTK-UHFFFAOYSA-N 0.000 description 8
- 238000005119 centrifugation Methods 0.000 description 6
- 239000000203 mixture Substances 0.000 description 6
- 235000011008 sodium phosphates Nutrition 0.000 description 6
- 239000003634 thrombocyte concentrate Substances 0.000 description 6
- VXGRJERITKFWPL-UHFFFAOYSA-N 4',5'-Dihydropsoralen Natural products C1=C2OC(=O)C=CC2=CC2=C1OCC2 VXGRJERITKFWPL-UHFFFAOYSA-N 0.000 description 5
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 5
- 230000000415 inactivating effect Effects 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 4
- 238000009472 formulation Methods 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 239000012815 thermoplastic material Substances 0.000 description 4
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 description 3
- 229930024421 Adenine Natural products 0.000 description 3
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 229930195725 Mannitol Natural products 0.000 description 3
- 229920012485 Plasticized Polyvinyl chloride Polymers 0.000 description 3
- 229960000643 adenine Drugs 0.000 description 3
- QKSKPIVNLNLAAV-UHFFFAOYSA-N bis(2-chloroethyl) sulfide Chemical group ClCCSCCCl QKSKPIVNLNLAAV-UHFFFAOYSA-N 0.000 description 3
- 239000008121 dextrose Substances 0.000 description 3
- 229910000397 disodium phosphate Inorganic materials 0.000 description 3
- 235000019800 disodium phosphate Nutrition 0.000 description 3
- 238000005304 joining Methods 0.000 description 3
- 239000000594 mannitol Substances 0.000 description 3
- 235000010355 mannitol Nutrition 0.000 description 3
- 239000004800 polyvinyl chloride Substances 0.000 description 3
- 238000005070 sampling Methods 0.000 description 3
- 235000002639 sodium chloride Nutrition 0.000 description 3
- 235000011083 sodium citrates Nutrition 0.000 description 3
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 239000004743 Polypropylene Substances 0.000 description 2
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 2
- 229920001400 block copolymer Polymers 0.000 description 2
- DQXBYHZEEUGOBF-UHFFFAOYSA-N but-3-enoic acid;ethene Chemical compound C=C.OC(=O)CC=C DQXBYHZEEUGOBF-UHFFFAOYSA-N 0.000 description 2
- 230000003750 conditioning effect Effects 0.000 description 2
- 238000010894 electron beam technology Methods 0.000 description 2
- 239000005038 ethylene vinyl acetate Substances 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 239000012533 medium component Substances 0.000 description 2
- 229960000907 methylthioninium chloride Drugs 0.000 description 2
- 229940021317 other blood product in atc Drugs 0.000 description 2
- 230000002186 photoactivation Effects 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 239000008279 sol Substances 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 229920001862 ultra low molecular weight polyethylene Polymers 0.000 description 2
- 230000035899 viability Effects 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- RBTBFTRPCNLSDE-UHFFFAOYSA-N 3,7-bis(dimethylamino)phenothiazin-5-ium Chemical compound C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 RBTBFTRPCNLSDE-UHFFFAOYSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 102000015081 Blood Coagulation Factors Human genes 0.000 description 1
- 108010039209 Blood Coagulation Factors Proteins 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- 239000004803 Di-2ethylhexylphthalate Substances 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 229920002633 Kraton (polymer) Polymers 0.000 description 1
- VAYOSLLFUXYJDT-RDTXWAMCSA-N Lysergic acid diethylamide Chemical compound C1=CC(C=2[C@H](N(C)C[C@@H](C=2)C(=O)N(CC)CC)C2)=C3C2=CNC3=C1 VAYOSLLFUXYJDT-RDTXWAMCSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- BJQHLKABXJIVAM-UHFFFAOYSA-N bis(2-ethylhexyl) phthalate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC BJQHLKABXJIVAM-UHFFFAOYSA-N 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 239000003114 blood coagulation factor Substances 0.000 description 1
- 230000003139 buffering effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 230000001010 compromised effect Effects 0.000 description 1
- 239000012611 container material Substances 0.000 description 1
- 238000010924 continuous production Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229940061607 dibasic sodium phosphate Drugs 0.000 description 1
- IPZJQDSFZGZEOY-UHFFFAOYSA-N dimethylmethylene Chemical group C[C]C IPZJQDSFZGZEOY-UHFFFAOYSA-N 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 230000012953 feeding on blood of other organism Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 229940045641 monobasic sodium phosphate Drugs 0.000 description 1
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- 150000002790 naphthalenes Chemical class 0.000 description 1
- 150000004780 naphthols Chemical class 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 125000001484 phenothiazinyl group Chemical class C1(=CC=CC=2SC3=CC=CC=C3NC12)* 0.000 description 1
- 239000003504 photosensitizing agent Substances 0.000 description 1
- IEQIEDJGQAUEQZ-UHFFFAOYSA-N phthalocyanine Chemical class N1C(N=C2C3=CC=CC=C3C(N=C3C4=CC=CC=C4C(=N4)N3)=N2)=C(C=CC=C2)C2=C1N=C1C2=CC=CC=C2C4=N1 IEQIEDJGQAUEQZ-UHFFFAOYSA-N 0.000 description 1
- 210000004180 plasmocyte Anatomy 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 235000019192 riboflavin Nutrition 0.000 description 1
- 239000002151 riboflavin Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- AYRVGWHSXIMRAB-UHFFFAOYSA-M sodium acetate trihydrate Chemical compound O.O.O.[Na+].CC([O-])=O AYRVGWHSXIMRAB-UHFFFAOYSA-M 0.000 description 1
- 229960000999 sodium citrate dihydrate Drugs 0.000 description 1
- BBMHARZCALWXSL-UHFFFAOYSA-M sodium dihydrogenphosphate monohydrate Chemical compound O.[Na+].OP(O)([O-])=O BBMHARZCALWXSL-UHFFFAOYSA-M 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 229940066767 systemic antihistamines phenothiazine derivative Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- DCTZJRUXIXPDJP-UHFFFAOYSA-N trihexyl 2-hydroxy-4-oxoheptane-1,2,3-tricarboxylate Chemical compound CCCCCCOC(=O)CC(O)(C(=O)OCCCCCC)C(C(=O)CCC)C(=O)OCCCCCC DCTZJRUXIXPDJP-UHFFFAOYSA-N 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
- A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- External Artificial Organs (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2008202709A AU2008202709B2 (en) | 2001-12-05 | 2008-06-19 | Methods and systems for preparing blood products |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/004,696 | 2001-12-05 | ||
| US10/004,696 US6936413B1 (en) | 2001-12-05 | 2001-12-05 | Methods and systems for preparing blood products |
| PCT/US2002/037554 WO2003049634A1 (en) | 2001-12-05 | 2002-11-22 | Methods and systems for preparing blood products |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2008202709A Division AU2008202709B2 (en) | 2001-12-05 | 2008-06-19 | Methods and systems for preparing blood products |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2002352877A1 AU2002352877A1 (en) | 2003-06-23 |
| AU2002352877B2 true AU2002352877B2 (en) | 2008-03-20 |
Family
ID=21712067
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002352877A Expired AU2002352877B2 (en) | 2001-12-05 | 2002-11-22 | Methods and systems for preparing blood products |
| AU2008202709A Expired AU2008202709B2 (en) | 2001-12-05 | 2008-06-19 | Methods and systems for preparing blood products |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2008202709A Expired AU2008202709B2 (en) | 2001-12-05 | 2008-06-19 | Methods and systems for preparing blood products |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6936413B1 (enExample) |
| EP (1) | EP1450716B1 (enExample) |
| JP (1) | JP2005511197A (enExample) |
| KR (1) | KR20050044689A (enExample) |
| CN (1) | CN100500231C (enExample) |
| AU (2) | AU2002352877B2 (enExample) |
| CA (1) | CA2469364C (enExample) |
| MX (1) | MXPA04005457A (enExample) |
| WO (1) | WO2003049634A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6936413B1 (en) * | 2001-12-05 | 2005-08-30 | Baxter International Inc. | Methods and systems for preparing blood products |
| US7052606B2 (en) * | 2001-12-10 | 2006-05-30 | Gambro, Inc. | Methods and apparatus for leukoreduction of red blood cells |
| US7183045B2 (en) * | 2002-04-24 | 2007-02-27 | Gambro Inc. | Removal of adenine during a pathogen reduction process in whole blood or red blood cell by dilution |
| KR100765249B1 (ko) * | 2006-03-23 | 2007-10-09 | 송영완 | 농축혈소판 겔 형성 트레이 |
| US20070243608A1 (en) * | 2006-04-14 | 2007-10-18 | Board Of Regents, The University Of Texas System | Platelet bioreactor |
| US8835104B2 (en) * | 2007-12-20 | 2014-09-16 | Fenwal, Inc. | Medium and methods for the storage of platelets |
| US8968992B2 (en) * | 2008-03-21 | 2015-03-03 | Fenwal, Inc. | Red blood cell storage medium for extended storage |
| US8871434B2 (en) * | 2008-03-21 | 2014-10-28 | Fenwal, Inc. | Red blood cell storage medium for extended storage |
| US11864553B2 (en) | 2009-10-23 | 2024-01-09 | Fenwal, Inc. | Methods and systems for providing red blood cell products with reduced plasma |
| US9164079B2 (en) * | 2011-03-17 | 2015-10-20 | Greyledge Technologies Llc | Systems for autologous biological therapeutics |
| AU2012240016B2 (en) | 2011-04-07 | 2016-11-10 | Fenwal, Inc. | Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates |
| WO2012151243A2 (en) * | 2011-05-03 | 2012-11-08 | Fenwal, Inc. | Platelet resuspension method and apparatus |
| WO2013043658A1 (en) * | 2011-09-19 | 2013-03-28 | Fenwal, Inc. | Red blood cells products and the storage of red blood cells in non-pvc bags |
| CN103028154B (zh) * | 2011-12-14 | 2015-10-07 | 南京双威生物医学科技有限公司 | 一种血小板分离袋及手工分离血小板的方法 |
| WO2014051537A1 (en) * | 2012-09-25 | 2014-04-03 | Biovec Transfusion, Llc | Device and method for removing additives in the blood products |
| US10098813B2 (en) | 2014-09-03 | 2018-10-16 | Sun Pharmaceutical Industries Limited | Perfusion dosage form |
| EA201890149A1 (ru) | 2015-06-26 | 2018-07-31 | Сирус Корпорейшн | Композиции криопреципитатов и способы их получения |
| EP3364986B1 (en) | 2015-10-23 | 2023-12-13 | Cerus Corporation | Pathogen-inactivated cryo-poor plasma and methods of use thereof |
| CN108697738A (zh) * | 2016-01-07 | 2018-10-23 | 塞鲁斯公司 | 用于制备血小板的系统和方法 |
| BR112018016287A2 (en) | 2016-02-09 | 2018-12-18 | Sun Pharmaceutical Industries Ltd. | Infusion system, method for administering directly to a patient in need thereof a dose of an antineoplastic drug and infusion container |
| US20180078694A1 (en) * | 2016-09-21 | 2018-03-22 | Fenwal, Inc. | Disposable Fluid Circuits for Extracorporeal Photopheresis with Integrated Source of Photoactive Agent |
| WO2018161020A1 (en) | 2017-03-03 | 2018-09-07 | Cerus Corporation | Kits and methods for preparing pathogen-inactivated platelet compositions |
| JP7495360B2 (ja) | 2019-02-15 | 2024-06-04 | テルモ株式会社 | バッグセット |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4322298A (en) * | 1981-06-01 | 1982-03-30 | Advanced Blood Component Technology, Inc. | Centrifugal cell separator, and method of use thereof |
| US4670013A (en) | 1982-12-27 | 1987-06-02 | Miles Laboratories, Inc. | Container for blood and blood components |
| IT1217938B (it) * | 1988-06-28 | 1990-03-30 | Girolamo Sirchia | Procedimento per la preparazione e la conservazione di concentrati eritrocitari e piastrinici |
| US5089146A (en) | 1990-02-12 | 1992-02-18 | Miles Inc. | Pre-storage filtration of platelets |
| SE9001271D0 (sv) | 1990-04-06 | 1990-04-06 | Eric Westberg | Blodpaase foer anvaendning vid separation av blod i komponenter |
| JP3182145B2 (ja) * | 1990-04-16 | 2001-07-03 | 日本赤十字社 | 血小板保存液 |
| JP2838725B2 (ja) | 1990-05-02 | 1998-12-16 | テルモ株式会社 | 血液採取器具 |
| JP2980663B2 (ja) | 1990-10-05 | 1999-11-22 | テルモ株式会社 | バッグ連結体 |
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-
2001
- 2001-12-05 US US10/004,696 patent/US6936413B1/en not_active Expired - Lifetime
-
2002
- 2002-11-22 CN CNB028242882A patent/CN100500231C/zh not_active Expired - Lifetime
- 2002-11-22 MX MXPA04005457A patent/MXPA04005457A/es active IP Right Grant
- 2002-11-22 EP EP02789836.0A patent/EP1450716B1/en not_active Expired - Lifetime
- 2002-11-22 CA CA2469364A patent/CA2469364C/en not_active Expired - Lifetime
- 2002-11-22 JP JP2003550685A patent/JP2005511197A/ja active Pending
- 2002-11-22 KR KR1020047008577A patent/KR20050044689A/ko not_active Ceased
- 2002-11-22 WO PCT/US2002/037554 patent/WO2003049634A1/en not_active Ceased
- 2002-11-22 AU AU2002352877A patent/AU2002352877B2/en not_active Expired
-
2005
- 2005-07-01 US US11/173,214 patent/US20050256443A1/en not_active Abandoned
-
2008
- 2008-06-19 AU AU2008202709A patent/AU2008202709B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US20050256443A1 (en) | 2005-11-17 |
| AU2008202709A1 (en) | 2008-07-17 |
| EP1450716B1 (en) | 2016-04-06 |
| CA2469364A1 (en) | 2003-06-19 |
| EP1450716A4 (en) | 2010-11-10 |
| CA2469364C (en) | 2013-04-09 |
| CN1599581A (zh) | 2005-03-23 |
| KR20050044689A (ko) | 2005-05-12 |
| WO2003049634A1 (en) | 2003-06-19 |
| CN100500231C (zh) | 2009-06-17 |
| EP1450716A1 (en) | 2004-09-01 |
| AU2002352877A1 (en) | 2003-06-23 |
| AU2008202709B2 (en) | 2010-06-17 |
| JP2005511197A (ja) | 2005-04-28 |
| MXPA04005457A (es) | 2004-10-11 |
| US6936413B1 (en) | 2005-08-30 |
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Owner name: FENWAL, INC. Free format text: FORMER APPLICANT(S): BAXTER INTERNATIONAL INC. |
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| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |