KR20050008757A - 세포 분화를 조절하고 골수증식성 질환 및 골수형성이상증후군을 치료하기 위하여 ｊｎｋ 또는 ｍｋｋ 저해제를사용하는 방법 - Google Patents

세포 분화를 조절하고 골수증식성 질환 및 골수형성이상증후군을 치료하기 위하여 ｊｎｋ 또는 ｍｋｋ 저해제를사용하는 방법 Download PDF

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KR20050008757A
KR20050008757A KR10-2004-7019520A KR20047019520A KR20050008757A KR 20050008757 A KR20050008757 A KR 20050008757A KR 20047019520 A KR20047019520 A KR 20047019520A KR 20050008757 A KR20050008757 A KR 20050008757A
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cells
group
stem cells
jnk
compound
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Korean (ko)
Inventor
로버트제이. 하리리
스트링데이비드아이
젤디스제롬비
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셀진 코포레이션
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • C12N5/0602—Vertebrate cells
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    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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KR10-2004-7019520A 2002-05-30 2003-05-30 세포 분화를 조절하고 골수증식성 질환 및 골수형성이상증후군을 치료하기 위하여 ｊｎｋ 또는 ｍｋｋ 저해제를사용하는 방법 Withdrawn KR20050008757A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US38425002P 2002-05-30 2002-05-30
US60/384,250 2002-05-30
US43483302P 2002-12-19 2002-12-19
US60/434,833 2002-12-19
PCT/US2003/017319 WO2003102151A2 (en) 2002-05-30 2003-05-30 Modulating cell differentiation and treating myeloprolifertive disorders with jnk/mkk inhibitors

Publications (1)

Publication Number Publication Date
KR20050008757A true KR20050008757A (ko) 2005-01-21

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KR10-2004-7019520A Withdrawn KR20050008757A (ko) 2002-05-30 2003-05-30 세포 분화를 조절하고 골수증식성 질환 및 골수형성이상증후군을 치료하기 위하여 ｊｎｋ 또는 ｍｋｋ 저해제를사용하는 방법

Country Status (9)

Country Link
US (1) US20040028660A1 (https=)
EP (1) EP1525308A4 (https=)
JP (1) JP2005528105A (https=)
KR (1) KR20050008757A (https=)
CN (1) CN1668733A (https=)
AU (1) AU2003231950A1 (https=)
CA (1) CA2488013A1 (https=)
MX (1) MXPA04011851A (https=)
WO (1) WO2003102151A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014042432A1 (ko) * 2012-09-12 2014-03-20 한양대학교 산학협력단 조혈세포 분화 유도 방법

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