KR20020077581A - Processing Methods of Health Food for the Control of Body Weight - Google Patents

Processing Methods of Health Food for the Control of Body Weight Download PDF

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KR20020077581A
KR20020077581A KR1020010017335A KR20010017335A KR20020077581A KR 20020077581 A KR20020077581 A KR 20020077581A KR 1020010017335 A KR1020010017335 A KR 1020010017335A KR 20010017335 A KR20010017335 A KR 20010017335A KR 20020077581 A KR20020077581 A KR 20020077581A
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weight
herbal
kelp
raw materials
extract
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KR1020010017335A
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Korean (ko)
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KR100448260B1 (en
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장상문
이주백
안홍
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(학)배영학숙
(주)명세당
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30Dietetic or nutritional methods, e.g. for losing weight
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/332Promoters of weight control and weight loss

Abstract

PURPOSE: A process of preparing special nutritious food in a tablet or spill by mixing powder and extracts of kelp and crude drug material followed by vitamin, inorganic matter, etc. is provided. Whereby, the nutritious food is effective for an overweight person to improve his health by reducing body fat, neutral lipid in serum and total cholesterol. CONSTITUTION: A main material containing kelp, adlay, aloe, Rhynchosia Nolubilis, Angelicae gigantis Radix, pine needle, Puerariae radix, Akebia quinata Decaisne, Polyporus umbellatus and Hordei fructus Germinatus, and an auxiliary material containing Plantago asiatica L., Poria cocos and Garcinia cambogia are ground. A main material containing Eucommia ulmoides, Acanthopanax Senticosus, Japanese apricot, Schizandra Fruit and folium Phyllostachys, and an auxiliary material containing Cervi parvum cornu and Liriope platyphylla Wang et Tang are extracted 5 times with water, mixed with a red ginseng extract followed by the above natural drug powder and a small amount of chito oligosaccharides, vitamins and inorganic matters.

Description

체중조절용 특수영양식품의 제조방법{Processing Methods of Health Food for the Control of Body Weight}Processing Methods of Health Food for the Control of Body Weight

본 발명은 다시마 및 한방 생약재를 이용한 체중조절용 특수영양식품의 제조방법에 관한 것으로 보다 상세하게는 다시마 및 한방 생약재의 일부를 분말로 하고 두충 및 생녹용 등은 물로 추출한 후 농축하여 홍삼 농축액을 소량 첨가하고 분말 생약재와 상호 혼합하여 체중 조절용 특수영양식품의 제조방법에 관한 것이다.The present invention relates to a method for preparing a special nutritional product for weight control using kelp and herbal herbal medicines. More specifically, a part of the kelp and herbal herbal medicines are powdered, and tofu and green antler are extracted with water and concentrated to add a small amount of red ginseng concentrate. The present invention relates to a method for preparing a special nutritional product for weight control by mixing with powdered herbal medicines.

인체는 체수분, 단백질, 체지방, 무기질의 4가지 주요성분으로 구성되어 있다. 그러나 정상인의 경우에는 평균 수분 60%, 단백질 22%, 지방 18%의 비율로 되어 있지만, 체중에서 지방이 차지하는 비율이 남자의 경우 약 15%전후, 여자의 경우에는 25%전후가 정상이라고 한다. 이보다 많은 양의 지방이 체내에 축적되는 경우를 비만이라고 한다.The human body consists of four main components: body water, protein, body fat and minerals. However, the average person is 60% moisture, 22% protein, and 18% fat, but the percentage of fat in the body is about 15% in men, 25% in women is normal. If more fat is accumulated in the body is called obesity.

일반적으로 비만은 체중이 과다한 상태를 말하지만 정확하게는 에너지를 사용하는 근육 성분과 에너지를 방출하는 체지방의 두 성분 사이에 균형이 깨져 체지방량이 상대적으로 많은 상태를 의미한다. 비만은 흔히 체지방량의 체중에 대한 비율, 즉 체지방의 비율로 진단하는데 체지방을 제외하면 체중은 근육량에 의해 대부분 결정되므로 체지방율은 근육량과 체지방량의 비율로 결정된다. 체지방량이 표준치 보다 높거나 근육량이 표준치 보다 부족한 경우, 체지방율은 높아진다. 그래서 비만은 체중만으로 판단되는 것이 아니며 날씬한 젊은 여성은 저체중에도 불구하고 근육량이 부족하면 비만으로 판정된다. 그러므로 이러한 신체를 구성하고 있는 성분을 정량적으로 측정하고 이들의 상호비율을 검사하여 비만치료의 선택에 사용하게 되며, 반복 측정하여 치료효과를 파악하는 수단으로도 쓰게 된다In general, obesity refers to a state of overweight, but precisely, a state in which a relatively large amount of fat is broken due to a balance between two components of energy-using muscle and energy-releasing body fat. Obesity is often diagnosed as the ratio of body fat mass to body weight, that is, the ratio of body fat. Except for body fat, body weight is largely determined by muscle mass, so body fat percentage is determined by the ratio of muscle mass and body fat mass. If the body fat amount is higher than the standard value or the muscle mass is lower than the standard value, the body fat rate is high. Therefore, obesity is not judged only by weight, and slender young women are judged to be obese when they lack muscle mass despite being underweight. Therefore, the components of the body are quantitatively measured and their mutual ratio is used to select obesity treatment, and it is also used as a means of determining the treatment effect by repeating the measurement.

한방의 사상체질학적으로 볼 때 비만인 대부분은 태음인이며 일부 소양인도 포함된다. 소화, 흡수 및 저장의 역할을 하는 간계 및 비계의 기능이 강하거나, 호흡, 혈액순환, 에너지 소모 및 배설을 관장하는 심계, 폐계 및 신계의 기능이 저하되면 비만이 생긴다고 한다.In the sasang constitution of the oriental medicine, most of the obese are Taeumin and some of the Soyangin are included. Obesity occurs when the function of the tricks and scaffolds, which play the role of digestion, absorption and storage, or when the functions of the heart, lungs and nervous system, which are responsible for breathing, blood circulation, energy consumption and excretion, are reduced.

사상체질별로 성격 및 특성과 추천할만한 다이어트방법을 살펴보기로 한다.Let's take a look at the characteristics, characteristics, and recommended diet methods by Sasang Constitution.

우선 태양인은 백명 중 한두명으로 성격은 강직하고, 과단성과 패기가 있는 반면 독선적이다. 행동은 창조적이나 의욕과잉으로 인해 영웅심에 빠지기 쉽다. 하체와 허리가 약해 장시간 앉아 있기가 힘들며 음식을 자주 토하거나 식도 협착이 잘되고 쉽게 흥분하며 귀울림, 두통 등이 잘 나타난다. 태양인의 체형은 주로 살이 고루 붙어있는 균형잡힌 체격이 많은데, 체중이 조금만 불어도 뚱뚱해 보이며 살도 쉽게 빠지는 편이다. 태양인의 다이어트에 좋은 약재로는 근육과 뼈를 강화시키는 오가피를 차로 마시는 방법이 있고 기관지가 약한 체질은 오전에 커피나 우유 대신 모과차 한잔과 함께 식사는 자몽 1/2쪽을 하는 방법, 또 토마토 2개 정도와 기름을 제거시킨 베이컨 2쪽으로 오전식사를 대신하는 방법도 좋은 것으로 알려져 있다.점심 식단으로는 국수를 좋아하면 메밀국수를 먹고, 오이나 양상추 같은 야채를 먹는 것도 도움이 되며, 야채를 싫어하는 태양인은 삶은 감자 1개와 오렌지 1개, 그리고 콩요리 100g정도를 먹어도 좋으며, 저녁식사로는 태양인은 모든 생선류나 조개류가 맞는 체질로서 생선 100g, 감자 100g, 옥수수 50g, 바나나 1개 혹은 감을 1개정도 대용하면 도움이 된다.First of all, the Sun is one or two out of a hundred, and the character is rigid, selfish and selfish. Action is prone to heroism due to creativity or overindulgence. Lower limbs and lower back is difficult to sit for a long time, frequent vomiting or narrowing of the esophagus, easy excitement, earrings, headaches and so on. Sunin's body shape is a balanced body with a lot of weight, but even a little weight seems to be fat and easy to lose weight. A good medicine for the sun person's diet is to drink muscles and bones, which can strengthen muscles and bones. Tea is weak for bronchial body. In the morning, instead of coffee or milk, a cup of quince tea is eaten. It's also a good idea to replace breakfast with a couple of bacon and two degreased bacons.If you like to eat noodles, eat soba noodles or vegetables like cucumbers or lettuce. You can eat one boiled potato, one orange, and 100g beans. For dinner, the sunin eats 100g fish, 100g potatoes, 50g corn, 1 banana or 1 persimmon. Substituting can also help.

다음으로 태음인은 한국인의 약 40%로서 너그러운 반면 속마음을 잘 드러내지 않으며 게으른 편이다. 또한 온몸에 살이 붙어 있어 땀이 나고 허리, 엉덩이, 허벅지가 거의 일자인 형이다. 흔히 직사각형 몸매라고도 불리는데 이런 체형을 가진 사람은 체중을 줄이는데 힘쓰기보다는 운동을 열심히 하는 것이 바람직하다. 태음인은 기관지가 약한 체질로서 녹용이나 칡, 오미자차, 도라지, 맥문동의 약재가 건강에 도움이 되며 이러한 약재의 처방으로 비만치료제가 형성되고 이뇨작용과 저항력이 커지는 율무차를 자주 먹으면 매우 좋다. 단지 변비가 있는 사람은 율무를 피하는 것이 좋다. 예를 들어 태음인의 다이어트 식단은 오전에는 율무차 1잔이나 칡차 1잔과 함께 시리얼 25g를 대신하는 것이 좋고, 점심으로는 콩수프와 빵 1개 정도를 먹거나 볶은 버섯 50g와 과일 2쪽을 식사대용으로 먹어도 좋으며, 과일은 수박이나 살구, 자두와 배를 즐기는 것이 건강에 매우 도움이 되고, 저녁으로는 부족한 단백질의 섭취가 필요한데 생선은 조기, 명태, 민어, 오징어와 같이 담백한 것으로 약 200g 정도와 사과나 배 등을 곁들인 요구르트 따위도 좋다. 생선을 싫어할 경우 스테이크 150g, 또는 닭고기 요리와 함께 오렌지 1개나 감자 100g 정도를 섭취해도 무관하다.Next, Taeumin is generous as about 40% of Koreans, while he is lazy and does not reveal his heart. In addition, the body is attached to the body sweating, waist, hips and thighs are almost straight. It is often referred to as a rectangular body, and it is desirable for a person of this type to exercise hard rather than trying to lose weight. Taeumin is a weak bronchial constitution as medicinal antler, 미, Schisandra tea, bellflower, McMoon-dong's medicine to help health, and the prescription of these medicines to form obesity treatment and diuretic action and resistance to ulmucha often eat very good. Only people with constipation should avoid the law. For example, in the morning, Taumin's diet should replace 25g of cereal with 1 cup of Yulmu or 1 cup of tea, and for lunch, eat bean soup and 1 bread, or 50g of fried mushrooms and 2 fruits. It is good to eat fruits, and watermelon, apricots, plums and pears are very good for your health, and you need to eat enough protein in the evening. Fish is light, such as premature, pollack, freshfish, squid, and about 200g. You can also eat yogurt with pears. If you don't like fish, you can eat 150g of steak, or one orange or 100g of potatoes with chicken.

소음인은 내성적이고 여성적인 성격으로 몸은 찬 편이고 엉덩이가 크고 어깨가 좁은 형이다. 다른 말로 서양체형이라고 부르기도 하는데 허벅지와 엉덩이에 살이 몰려 있는 것이 특징이다. 당연히 식이요법과 운동을 함께 하여 몸매의 균형을 잡도록 해야 한다.The noise person is introverted and feminine in nature, with a cold body, big hips and narrow shoulders. In other words, it is called a Western figure, and it is characterized by thighs and hips. Of course, diet and exercise together to balance the body.

소음인은 과민하여 신경성 질환이 많고 작은 일에도 세심하며, 몸이찬 체질이므로 한방요법으로는 인삼이나 부자, 계피, 백출 등의 따뜻한 약재를 이용하여 비만 치료를 하고 있으며, 옥수수나 찹쌀, 쇠고기, 닭고기, 가자미, 민어, 미역, 김 등의 음식이 잘 맞는 체질이다. 소음인의 다이어트 식단으로는 아침에 쑥차나 당근즙과 함께 토마토(또는 복숭아)를 먹는 것이 이롭다. 점심에는 빵 1개와 치즈 100g, 건포도 1찻술 정도의 식단이나, 감자 1개와 옥수수 1개의 식단도 좋고, 시금치나 야채수프와 함께 토마토 1개나 샐러드로 대치해도 좋은 식단이 된다. 저녁에는 감자와 당근 100g과 닭고기 150g 이나 생선(가자미, 민어, 굴비)150g정도로 식단을 짜면 소음인의 건강을 유지하는 다이어트 식단이 될 수 있다.Noisin is sensitive and has a lot of neurological disorders and attentive to small things, and because the body is full of constitution, herbal treatments are used to treat obesity with warm medicines such as ginseng, rich man, cinnamon, and baekchul, corn, glutinous rice, beef, chicken, Flounder, minfish, seaweed, seaweed, etc. is a good constitution. For Soumin's diet, it is beneficial to eat tomatoes (or peaches) with wormwood or carrot juice in the morning. For lunch, a meal of bread, 100g of cheese, and a teaspoon of raisins, or a meal of potatoes and corn, can be replaced by a tomato or salad with spinach or vegetable soup. In the evening, a diet of 100g potatoes and carrots and 150g chicken or 150g of fish (flounder, mink, oyster) can be a diet to maintain the health of the noise person.

그러나 최근에 이르러 바쁜 사회생활들로 인하여 이와 같은 규칙을 지키기에는 매우 어려우므로 한방다이어트식품 등을 일정기간 동안 섭취하여 비만을 해소하는 방법을 사용할 수 있다. 또한 식생활의 패턴이 지방을 많이 함유하는 서양식품과 인스탄트식품의 과잉섭취로 인하여 지방 및 각종 영양분의 소화과정에서 발생되는 활성산소(superoxide)는 피부조직의 노화 및 스트레스 등을 유발시킴과 동시에 각종 성인병을 유발하는 직접적인 원인이 되며, 비만으로 인하여 혈액 중 지질농도의 증가와 몸에 유익한 고밀도-저단백 콜레스테롤(HDL)의 감소 등으로 심혈관계 질환을 유발한다(유영상저 식이요법 p10-11(1997)참조).However, in recent years, it is very difficult to keep these rules due to busy social life, so you can use the method of relieving obesity by eating herbal diet foods for a certain period of time. In addition, the pattern of eating habits is due to the excessive intake of Western foods and instant foods that contain a lot of fat, and the free radicals generated during digestion of fat and various nutrients cause aging and stress of skin tissues and various adult diseases. And obesity cause cardiovascular diseases, such as increased lipid levels in the blood and a decrease in high-density-low protein cholesterol (HDL), which is beneficial to the body. (Image 10: p10-11 (1997) Reference).

특히 SOD는 생체 내에서 활성산소인 활성산소를 삼중항산소로 전환시켜 줌으로써 생체방어역할을 하는 효소이며, SOD 유사활성물질은 효소는 아니지만 활성산소를 스캐빈징(scavenging)하는 물질로 기작은 다르나 체내에서의 역할이 SOD와 유사한 작용을 나타낸다. 특히 한방재료들은 식물체내 2차 대사산물로 생성된 플라보노이드 화합물 및 카로테노이드 화합물 등의 항산화물질들이 다량으로 함유되어 있으므로 인체 내에서 SOD유사활성을 증대시킬 수 있을 것으로 판단된다. 그래서 비만치료를 단순히 날씬하기 위한 미용을 위한 차원이 아니라, 성인병 예방을 위한 적극적인 치료수단으로 접근하여야 할 것이다.In particular, SOD is an enzyme that plays a role in bioprotection by converting active oxygen, which is active oxygen, into triplet oxygen in vivo, and SOD-like active substance is not an enzyme but a substance that scavengs active oxygen. Role in the body shows a similar effect to SOD. In particular, herbal materials contain a large amount of antioxidants such as flavonoid compounds and carotenoid compounds produced as secondary metabolites in plants, which may increase SOD-like activity in the human body. Therefore, obesity treatment should be approached as an active treatment for preventing adult diseases, not just for slimming.

어떤 연구결과에 의하면 솔잎분말을 콜레스테롤을 급여한 흰쥐에 급여한 결과 혈장 총콜레스테롤 함량은 하락하였으며, 항산화능을 나타내는 간장 내 글루타치온 페록시다제의 활성치는 처리구별 유의성이 없는 것으로 보고되어 있다(이은 외1, 솔잎분말이 고 콜레스테롤 급여 흰쥐의 체지질 구성과 TBARS량에 미치는 영향, 한국식품영양학회지, 32(5): p1186-1190(2000) 참조).According to a study, when pine needle powder was fed to cholesterol-fed rats, the plasma total cholesterol content was decreased, and the activity of glutathione peroxidase in liver, which shows antioxidant activity, was not significantly different among treatment groups. 1, Effect of pine needle powder on the lipid composition and TBARS in high cholesterol fed rats, Korean Journal of Food and Nutrition, 32 (5): p1186-1190 (2000)).

한편, 연구결과에 의하면 대두추출물을 고지방 식이 및 동물성 지방식이에 의한 혈 중 지질 감소효과가 있었으며, 식물성 지방식이와 같이 섭취할 경우 상승효과가 있다고 보고하였다(신미경 외1, 대두추출물이 지방이식을 급여한 흰쥐의 혈청지질성분에 미치는 영향, 한국식품영양학회지, 31(3): p809-814(1999) 참조). 그렇다면, 한방 다이어트의 보약 성분엔 어떤 것이 있는지를 살펴본다.According to the results of the study, soybean extracts were effective in reducing lipids in the blood by high-fat diets and animal fat diets, and synergistic effects were obtained when ingested with vegetable fat diets. Effects of Serum Lipids on Rats Fed, See Korean Journal of Food and Nutrition, 31 (3): p809-814 (1999). If so, look for what the herbal ingredients in the herbal diet.

비만해소에 효능을 가지고 있는 한방재료들을 살펴보면(전국 한의과대학 본초학 교수협의회: 본초학, 도서출판 영림사(1991)참조), 혈액 순환을 돕는 당귀·천궁·홍화·소목 등이 있으며, 의이인(薏苡仁)은 몸에 불필요한 수기(水氣)와 습기를 제거, 피를 맑게 하면서 순환을 돕는다. 숙지황(熟地黃)은 비만치료에 필수적인 입맛을 감소시키는 효능이 있으며, 적게 먹었을 때에는 변비 예방을 물론 지구력을 유지시켜 준다. 당귀(當歸)는 혈액의 기능을 돕고, 이뇨, 항균, 진정, 진통의 효과도 있고, 홍화(紅花), 소목(蘇木), 천궁 등과 함께 비만자에게는 필수적인 약재로 알려져 있다. 또한 천궁(川芎)은 체중 감량을 위해 음식 섭취량을 대폭 줄일 때 나타나기 쉬운 두중통(頭重痛:머리가 아프거나 무겁고 어지러운 증세)을 없애주는 효능이 있으며, 홍화, 소목은 혈액 속의 지방과 지질을 제거하며, 피를 맑게 해주고, 감초(甘草)는 입맛을 감소시키며, 한약재들의 독성을 완화, 강한 단맛을 함유하고 있어 식욕을 감소시킨다. 으름덩굴나무 줄기인 목통(木通)은 비만증 치료에 필수적으로 활용되는데, 음식물 섭취의 급격한 감소로 인해 지방이 다량 분해될 때 생기는 노폐물을 소변을 통해 효율적으로 배출시켜 주며, 저항력 감소로 인한 제반 질병의 발생을 막아준다. 백복령(白茯笭)은 소나무의 묵은 뿌리 주변에 기생하는 불규칙한 모양의 균체를 가리키며, 체내 소변의 배출을 원활하게 하여 지방층의 수분을 제거하고 체중을 줄이는 한편, 부종 등을 감소시키는 것으로 알려져 있다.Looking at herbal ingredients that are effective in relieving obesity (National Institute of Oriental Medicine: see Herbology, Book Publishing Younglimsa (1991)), donkey, cheongung, safflower, and sapling to help blood circulation. ) Helps circulate while removing unnecessary water and moisture from the body and clearing blood. Sukji Hwang (Maturity 地 黄) is essential for the treatment of obesity to reduce the taste, and when eaten less constipation prevents and maintains endurance. Angelica (當歸) to help the function of the blood, diuretic, antibacterial, soothing, analgesic effect, safflower (紅花), joiner (蘇木), cheongung, etc. are known as essential medicines for obese people. In addition, cheongung has the effect of eliminating the pain in the head due to heavy reduction of food intake for weight loss. Safflower and sapling remove the fat and lipids in the blood. It clears blood, licorice (甘草) reduces appetite, alleviates the toxicity of herbal medicines, and contains a strong sweet taste, which reduces appetite. The tree trunk, an ivy tree trunk, is essential for the treatment of obesity, which efficiently discharges waste products through urine due to the rapid reduction in food intake, and all diseases caused by reduced resistance. Prevents the occurrence of Baekbokyeong (白 茯 笭) refers to the irregular shape of the parasitic bacteria around the old roots of pine, it is known to smooth the discharge of urine in the body to remove the moisture of the fat layer, reduce weight, and reduce edema.

이밖에도 칡뿌리인 갈근(葛根)은 해열, 해기(解肌:근육을 풀어주는 기능), 갈증을 없애는 효능이 있으며, 보양제(補陽劑)로 많이 이용되고 있는 녹용(鹿茸)은 식이요법 때 오는 어지러움을 방지할 수 있으며, 성장기 어린이 성장촉진, 수험생의 기억력 및 집중력 향상 등에 도움이 되며, 비만여성의 경우 생리조절·불임증에 효과가 있다.In addition, the root roots of brown root (葛根) has the effect of eliminating fever, haegi (delivering muscles), thirst, and antler, which is widely used as a nourishing agent, comes from diet Dizziness can be prevented, and it helps to promote the growth of children in the growing season, improve the memory and concentration of the examinee, and the obesity women are effective in controlling physiology and infertility.

두충(杜沖), 독활(獨活), 우슬(牛膝), 속단(續斷)등의 약재들은 체중감소 시 예상되는 근육, 뼈 및 관절의 약화를 방지하고, 성장기에 키의 성장을 돕는 데 효과적이다.Herbs such as larvae, venom, dew, and fasteners prevent the weakening of muscles, bones and joints expected to lose weight, and help to grow tall during the growing season. Is effective.

일반적으로 비만의 예방과 치료는 식이요법, 행동수정요법, 운동요법을 결합하여 많이 하고 있다. 이중에서 운동요법과 부작용이 없는 한방다이어트요법을 함께 실행함으로써 신체의 활동량을 증가시킴으로써 소비되는 칼로리를 증가시키며, 지방의 연소와 혈중 지질, 혈압, 기분, 태도 등에 좋은 영향을 미치게 되므로, 결과적으로 행동수정요법을 동시에 겸하게 되는 결과를 가져오게 된다. 이는 한방다이어트요법이 소화기계의 활발한 연동운동을 유도하여 무리한 식이요법의 부작용을 막을 수 있기 때문이다. 체중을 줄이는 방법에는 첫째 고통스럽게 체중을 줄여서는 안되며, 둘째 체중을 줄이는 동안 부작용이 없어야 하고, 셋째 체중의 감량에 성공한 후에도 원상 복귀되는 일이 없어야 한다. 한방재료를 섭취하여 체지방 및 체중을 감소시키는 한방다이어트의 장점은 고통과 부작용이 없으며, 요요 현상이 없이 건강하고 아름답게 살을 빼는 데 있다.In general, the prevention and treatment of obesity is a combination of diet, behavior modification, exercise therapy. In addition, exercise therapy and herbal diet therapy without side effects can increase the amount of calories consumed by increasing the amount of activity of the body, and thus have a good effect on the burning of fat and blood lipids, blood pressure, mood, and attitudes. This results in a combination of fertilization therapy. This is because herbal diet therapy can induce active peristalsis of the digestive system and prevent side effects of excessive diet. The first way to lose weight is not to lose weight painfully, secondly, there should be no side effects while losing weight, and the third should not return to normal after successful weight loss. The benefits of herbal diets to reduce body fat and weight by ingesting herbal ingredients are painless and no side effects, and there is no yo-yo phenomenon to lose weight healthily and beautifully.

위성언외1의 중년성인의 비만·빈혈과 식생활 태도에 대한 연구결과(학국식품영양학회지, 6(1):p25-30(1993) 참조)에 의하면 비만 및 빈혈은 식품의 섭취뿐만 아니라 식생활을 영위하는 태도에 의해서도 좌우될 수 있다고 보고하였다. 개정 식품공전에 따르면 비만증을 치료하는 다이어트식품은 특수영양식품군에서 식사대용식품 중에서, “체중조절용 식품”으로 분류되어, “체중의 감소 또는 증가가 필요한 사람을 위하여 하루에 요구되는 열량을 가감하여 섭취할 수 있도록 제조 가공된 식품”으로 정의되어 있다(식품의약품안전청: 식품공전,p287(2000) 참조).According to a study on obesity, anemia and dietary attitudes of middle-aged adults in satellite et al. (See Korean Journal of Food and Nutrition, 6 (1): p25-30 (1993)), obesity and anemia lead not only to food but also to diet. It could be influenced by their attitude. According to the revised Food Code, diet foods that treat obesity are classified as “weight control foods” among meal replacement foods in the special nutritional supplement group, and are ingested by adding or removing the required calories per day for those who need to reduce or increase their weight. Food, manufactured and processed so that it can be used (see Food and Drug Administration: Food Code, p. 287 (2000)).

종래 한방제품은 율무를 주재료로 하여 저령, 두충 등 8∼10종의 생약재를 환제로 복용하는 방법이었고, 다시마 단일 추출제품의 환제품이 배설기능강화와 비만해소제품으로 제조 판매되고 있으며, 또 차전자피와 HCA, 키토산 등을 주재료로 하는 섬유소제품과 체지방 축적방지제품 등이 수입판매 되고있다.Traditionally, herbal medicines were made by taking Yulmu as a main ingredient and taking 8 to 10 kinds of herbal medicines such as ghost, tofu, etc. as pill, and pill products of single extract of kelp are manufactured and sold as products to enhance excretion and obesity. In addition, fiberglass products and body fat accumulation prevention products, which are mainly made of HCA and chitosan, are imported and sold.

이상과 같이 한방 생약재, 다시마, 율무, 차전자피, HCA 등을 주재료로한 식품은 제조 판매되고 있지만, 현재까지는 다시마와 한방생약을 이용한 체지방율 및 총콜레스테롤 함량 감소를 위한 체중조절용 특수영양식품의 조성물은 공지된 바 없었다.As described above, foods based on herbal medicines, kelp, yulmu, chameul, HCA, etc. are manufactured and sold, but until now, the composition of weight loss special nutrition products for reducing body fat percentage and total cholesterol content using kelp and herbal medicines is known. It never happened.

본 발명은 다시마 및 한방 생약재를 주재료로 하여 한방재료를 함유하는 체중조절용 특수영양식품의 제조방법을 제공함에 있다.The present invention is to provide a method for producing a special nutritional product for weight control containing herbal ingredients as a main material kelp and herbal medicine.

본 발명의 다른 목적은 체지방율, 혈청 중성지질 및 총콜레스테롤 함량의 감소를 위한 비만자의 건강증진에 효과가 있는 체중조절용 특수영양식품의 제조방법을 제공함에 있다.It is another object of the present invention to provide a method for preparing a special nutritional product for weight control, which is effective for the health promotion of obese for the reduction of body fat percentage, serum triglyceride and total cholesterol content.

이를 위해 본 발명은 다시마, 율무, 알로애, 흑두, 당귀, 솔잎, 갈근, 으름, 저령, 맥아를 포함하는 주원료와, 차전차피, 백복령 및 가르시니아 캄보지아를 포함하는 부원료인 한방 생약재를 분말상태로 하고; 두충, 가시오가피, 매실, 오미자및 죽엽을 포함하는 주원료와 생녹용과 맥문동을 포함하는 부원료에 5배의 물을 가하여 90∼130℃의 온도에서 1∼4시간 동안 고압 가열, 추출하며; 상기 추출액에 홍삼농축액 0.1중량%를 첨가하여 액상의 추출액을 제조하고; 소정의 비율로 배합된 상기 분말 한방 생약재와 수용성 키토올리고당, 비타민류 및 무기성분류등을 소량 첨가하여 상기 추출액과 혼합하여 반죽하고; 상기 반죽물을 환으로 형성하여 타정 및 열풍 건조시킴을 기술적인 특징으로 한다.To this end, the present invention is a powdered herbal herbal medicine containing the main raw materials including kelp, yulmu, aloe, black bean, donkey, pine needles, carp roots, ulzzang, herb, malt, and secondary ingredients including chajeonchapi, baekbokyeong and garcinia cambogia ; 5 times of water was added to the main raw materials including tofu, barley, plum, Schizandra chinensis and bamboo leaf, and the subsidiary raw materials including fresh antler and pulmonary dong to heat and extract for 1 to 4 hours at the temperature of 90-130 ° C; Adding 0.1% by weight of red ginseng concentrate to the extract to prepare a liquid extract; Adding a small amount of the powdered herbal herbal medicines, water-soluble chitooligosaccharides, vitamins, and inorganic components, blended in a predetermined ratio, and kneading the mixture with the extract; Forming the dough into a ring is characterized by drying the tableting and hot air.

본 발명에 있어서 분말상 한방 생약재 및 액상추출물은 다시마15중량%, 율무10중량%, 알로애6중량%, 흑두5중량%, 당귀5중량%, 솔잎5중량%, 갈근5중량%, 으름3중량%, 저령3중량%, 맥아3중량%, 차전자피12중량%, 백복령5중량%, 가르시니아, 수용성 키토올리고당, 비타민류 및 무기성분(Fe, Ca, Zn)1중량%, 홍삼농축액0.1중량%, 두충6중량%, 가시오가피3중량%, 매실3중량%, 오미자3중량%, 죽엽2.9중량%, 생녹용2중량%, 맥문동2중량%의 배합비율이 바람직하다.In the present invention, powdered herbal herbal medicines and liquid extracts are 15% by weight of kelp, 10% by weight, lychee radish, 6% by weight, black bean 5% by weight, Angelica 5% by weight, pine needles 5% by weight, 5% by weight of brown root, 3% by weight , 3% by weight of malt, 3% by weight of malt, 12% by weight of chaff, 5% by weight of baekbokyeong, garcinia, water-soluble chitooligosaccharides, vitamins and inorganic components (Fe, Ca, Zn) 1% by weight, red ginseng concentrate 0.1% by weight, tofu A blending ratio of 6% by weight, 3% by weight of thorny vinegar, 3% by weight of plum, 3% by weight of Schizandra chinensis, 2.9% by weight of bamboo leaves, 2% by weight of green antler, and 2% by weight of wormwood are preferred.

이하 본 발명을 좀더 구체적으로 설명하면 다음과 같다.Hereinafter, the present invention will be described in more detail.

예로부터 민간요법으로 변비해소 및 비만해소에 많이 사용되고 있는바, 본 발명자들은 다시마를 주원료로 하여 SOD유사활성이 높은 한방재료들을 배합하여, 체지방율, 혈장 중성지질 및 총 콜레스테롤의 함량을 감소시켜 비만을 해소하기 위한 체중조절용 특수영양식품을 개발할 목적으로 비만도가 높은 성인 38명을 대상으로 임상실험을 수행하였다.Since ancient times, it has been widely used for relieving constipation and obesity by folk remedies, and the present inventors combine herbal ingredients with high SOD-like activity using kelp as a main ingredient to reduce body fat percentage, plasma triglyceride, and total cholesterol to obesity A clinical trial was conducted on 38 adults with high obesity to develop a special dietary supplement for weight control.

1. 임상실험 대상자 선정1. Selection of subjects for clinical trial

체중조절용 식품을 개발하여 임상실험대상자를 모집한후자동체성분검사기(In Body)를 이용하여 측정한 분석결과를 기초로 하여 비만진단을 실시하여 비만도가 높은 순으로 38명을 선정하였다. 그리고 비만도가 높은 순으로 선정된 임상실험 대상자들을 다음과 같은 항목으로 설문 조사하여 체질의 특성을 파악하여 한방의학에 기초를 두고 있는 사상체질에 따라 분류하였다. 그 결과는 표1과 같다.After developing foods for weight control and recruiting clinical test subjects, 38 subjects were selected in order of obesity based on the results of the obesity diagnosis based on the analysis results measured using an automatic body composition analyzer (In Body). The subjects who were selected in the order of high obesity were surveyed with the following items to identify the characteristics of the constitution and classified according to Sasang constitution based on Oriental medicine. The results are shown in Table 1.

임상실험 대상자의 체질조사 항목Constitutional Items of Clinical Subjects 항목Item 항목수Number of items 세부조사 항목Detailed item 체형form 44 체격특징Physique 외모와 골격의 특징Features of the appearance and skeleton 외관상 발달된 부분An apparently developed part 가슴의 모양Shape of chest 외모look 66 얼굴 전체의 특징Features of the whole face 얼굴의 색깔Color of face 얼굴의 모양Shape of face 눈빛의 특징Eye characteristics 피부의 특징Skin features 손, 발의 특징Hand and foot features 성격Personality 22 기질 및 성격의 장점Temperament and personality advantages 기질 및 성격의 단점Disadvantages of Temperament and Personality 습성habit 44 걸음걸이의 특징Characteristic of gait 음성의 특징Voice features 말할 때의 습관Customs when speaking 오감 중 가장 발달한 감각기관The most developed sensory organs of the five senses 식습관Eating habits 66 가장 좋아하는 음식물Favorite Food 가장 좋아하는 과일Favorite fruit 가장 좋아하지 않거나, 알레르기를 일으킨 음식Least favorite or allergic food 음식물에 대한 기호Symbol for food 물 마시는 모양Water drinking shape 커피를 먹고 난 후의 수면상태Sleep after eating coffee 증상Symptom 44 땀을 흘리는 특징Sweating features 대변상태Stool status 평소 자주 느끼는 신체의 증상Symptoms of your body that you usually feel 평소 잘 나타나는 병증의 증상Symptoms of the usual well-known symptoms

2. 실험재료2. Experimental materials

1) 원재료의 배합비율1) Mixing ratio of raw materials

임상실험에 사용되는 한방다이어트식품의 원재료 배합비율은 표2와 같다.The blending ratio of raw materials of herbal diet foods used in clinical trials is shown in Table 2.

한방다이어트식품의 원재료 배합비율Raw Material Blending Ratio of Herbal Diet Food 분류Classification 원재료명Raw material name 배합비율(%)Compounding ratio (%) 비고Remarks 주원료Main raw material 1. 다시마(昆布)Kelp 1515 분말powder 2. 율 무(薏苡仁)2. Yulmu 1010 3. 알로애3. Aloe 66 4. 흑 두(黑豆)4. Black bean 55 5. 당 귀(當歸)5. Party Ears 55 6. 솔 잎(松葉)6. Brush leaves 55 7. 갈 근(葛根)7. Brown root 55 8. 으 름(木通)8. 木 通 33 9. 저 령(猪笭)9. Heraldry 33 10. 맥 아(麥芽)10. Malt 33 부원료Raw materials 11. 차전자皮(車前子皮)11. Tea Electronics 1212 12. 백복령(白茯笭)12. Baekbokyeong (白 茯 笭) 55 13. 가르시니아캄보지아13. Garcinia Cambogia 소량handful 1One 14. 수용성 키토올리고당14. Water Soluble Chitooligosaccharide 소량handful 15. 비타민류15. Vitamins 소량handful 16. 무기성분(Fe, Ca, Zn)16. Inorganic Components (Fe, Ca, Zn) 소량handful 주원료Main raw material 17. 홍삼추출액(홍삼사포닌70mg/g)17. Red ginseng extract (red ginseng saponin 70mg / g) 0.10.1 추출extraction 18. 두 충(杜沖)18. Two Chung 66 19. 가시오가피(五加皮)19. Gioniogapi (五加皮) 33 20. 매 실(梅實)20. Plums 33 21. 오미자(五味子)21. Schisandra 33 22. 죽 엽(竹葉)22. Bamboo Leaf 2.92.9 부원료Raw materials 23. 생녹용(生鹿茸)23. Fresh antler 22 24. 맥문동(麥門冬)24. McMoon-Dong 22

예로부터 변비해소 및 각종 식품조리 및 가공에 많이 사용되고 있는 다시마Kelp has been widely used for relieving constipation and cooking and processing various foods.

분말을 주원료로 하여 율무, 알로애, 솔잎, 검은콩 등 10종은 분말상 주원료이며 홍삼, 두충, 가시오가피, 매실, 오미자, 대나무잎 등은 추출용 주원료를 배합하였다. 부원료로는 차전자피, 백복령 및 가르시니아캄보지아(hydroxy citric acid), 생녹용 및 맥문동 등을 부원료로 배합하고, 수용성 키토올리고당, 비타민류, 무기성분류 등을 소량 첨가하였다.The main ingredients were powder, main ingredients such as yulmu, aloe, pine needles, black beans, powdered main raw materials, and red ginseng, tofu, thorny cucumber, plum, schizandra and bamboo leaves were mixed with main raw materials for extraction. As a secondary raw material, cha jeonpi, Baekbokryeong and garcinia cambogia (hydroxy citric acid), raw antler and mackmundong were added as a secondary raw material, and water-soluble chitooligosaccharides, vitamins, and inorganic components were added in small amounts.

2) 환제조방법2) Reproduction Method

(1) 원료를 깨끗하게 세척한 후 건조한다.(1) Clean the raw materials and dry them.

(2) 추출액의 제조 : 주원료 두충, 가시오가피 등의 5종과 부원료 생녹용 및 맥문동을 표2의 배합비율에 따라 배합하여 121℃에서 4시간 동안 고압, 추출하여 일정농도의 고형분이 유지되도록 한다.(2) Preparation of extracts: 5 kinds of main raw materials such as larvae, prickly pears, etc., and raw antler and gymundong were mixed according to the mixing ratios of Table 2, and extracted at high pressure at 121 ° C. for 4 hours to maintain a constant solid content.

(3) 다시마, 율무 등 분말원료들을 표2의 배합비율에 따라 정확한 함량을 배합하여 추출액과 혼합하여 반죽한다.(3) Mix the raw materials such as kelp and yulmu according to the mixing ratio of Table 2, and mix it with the extract.

(4) 제환기로 환을 성형하거나, 타정기를 통하여 타정하고 열풍 건조한다.(4) A ring is formed by a ventilation machine, or it is compressed through a tableting machine and dried by hot air.

(5) 건조 : 수분함량 10%이하까지 건조한다.(5) Drying: Dry up to 10% or less of moisture.

3. 영양성분의 분석3. Analysis of Nutritional Components

임상실험용 다이어트식품 중에 함유되어 있는 일반성분 및 미량성분의 정량은 AOAC법(Official Methods of Analysis (1984)에 준하여 측정하였다.Quantitative determination of general and trace components in clinical trial diet foods was measured according to the AOAC method (Official Methods of Analysis (1984)).

4. 원재료의 SOD 유사활성도 측정4. Measurement of SOD-like activity of raw materials

1)Superoxide radical 소거활성(Xanthine-xanthine oxidase cytochrome c 환원법)1) Superoxide radical scavenging activity (Xanthine-xanthine oxidase cytochrome c reduction method)

UV cell에 시료 0.2㎖, 50mM 인산완충용액(pH 7.8) 1.2㎖, 1mM xanthine 0.2㎖, 0.05mM cytochrome c 0.2㎖ 및 550nm에서 3분간 흡광도를 측정하여 시료 무첨가군에 대한 시료첨가군의 비를 측정하였다.Measure the absorbance at the UV cell for 3 min at 0.2 ml of sample, 1.2 ml of 50 mM phosphate buffer (pH 7.8), 0.2 ml of 1 mM xanthine, 0.2 ml of 0.05 mM cytochrome c, and 550 nm to determine the ratio of the sample-added group to the sample-free group. It was.

2) Hydroxyl radical 소거활성(2-deoxyribose oxidation법)2) Hydroxyl radical scavenging activity (2-deoxyribose oxidation method)

0.1mM FeSO4/ 0.1mM EDTA용액 0.2㎖, 10mM H2O20.2㎖을 가하여 37℃에서 4시간 반응 후, 2.8% TCA(Trichloroacetic acid) 1㎖를 가하여 반응을 중지시키고, 1.0% TBA(Thiobarbituric acid) 1㎖를 가하여 100℃에서 10분 동안 가열 후 급냉하여 532nm에서 흡광도를 측정하여 시료 무첨가군의 비를 측정하였다.0.2 ml of 0.1 mM FeSO 4 / 0.1 mM EDTA solution and 0.2 ml of 10 mM H 2 O 2 were added for 4 hours at 37 ° C. Then, 1 ml of 2.8% TCA (Trichloroacetic acid) was added to stop the reaction and 1.0% TBA (Thiobarbituric) was added. 1 ml of acid) was added thereto, heated at 100 ° C. for 10 minutes, and then rapidly cooled to measure absorbance at 532 nm.

5. 섭취기간 및 섭취방법5. Intake period and intake method

표2의 원재료 배합비율에 따라서 제조된 환(1회 복용량 3g)을 3개월(12주일) 동안 동일한 방법으로, 1일 3회 식사 20분전에 섭취하였다. 또한 임상실험 기간 동안에 섭취하는 체중관리 및 식사에 대한 다이어트일지를 작성하여 실험기간 중에 섭취하는 식생활의 칼로리를 환산하여 임상결과의 고찰에 참고하였다.The pill (one dose 3g) prepared according to the raw material compounding ratio of Table 2 was taken in the same manner for three months (12 weeks), 20 minutes before a meal three times a day. In addition, diet diary for weight management and meal ingested during the clinical trial period was prepared and the calories of dietary intake during the experimental period were converted into references for consideration of clinical results.

6. 체성분 분석 및 전위, 요위의 측정방법6. Body composition analysis and measurement method of dislocation and point

임상실험 대상자에 대하여 체중조절용식품을 섭취하기 전에 2회 측정하여 평균값으로 섭취 전의 체성분 값으로 정하였으며, 4주일(28일) 단위로 자동체성분 분석기(In Body)를 이용하여 신장, 체중, 체지방량, 체지방율, 복부지방율, 체수분 및 기타 영양성분들을 측정하였다. 그리고, 전위 및 요위의 변화는 4주일(28일)단위로 측정하였다.The subjects were measured twice before taking the weight control food and the average value was determined as the body composition value before ingestion.The body weight, body fat, body weight, and body weight were measured using an automatic body composition analyzer (In Body) every four weeks (28 days). Body fat percentage, abdominal fat percentage, body moisture and other nutrients were measured. In addition, the change of the electric potential and the point was measured in units of 4 weeks (28 days).

7. 혈액 분석방법7. Blood analysis method

체중조절용식품의 섭취기간 중 건강상태의 변화를 조사하기 위하여 4주일(28일)단위로 채혈하여 혈액 중 중성지방, 총 콜레스테롤, 간기능(GOT, GPT), 혈색소, 당질, 단백질, 알부민 및 요산의 함량을 대구보건대학 협동병원인 대구병원 임상병리실에서 분석하였다.In order to investigate the changes in health status during the intake of weight-control foods, blood samples were collected in units of 4 weeks (28 days), and triglycerides, total cholesterol, liver function (GOT, GPT), hemoglobin, sugar, protein, albumin and uric acid in the blood. Was analyzed in the clinical laboratory of Daegu Hospital, a cooperative hospital of Daegu Health University.

결과 및 고찰Results and Discussion

1. 임상실험 대상자 현황1. Current Status of Subjects

비만도가 높은 임상대상자들의 체질에 관한 설문조사, 실험기간 중 다이어트식품의 결식율 및 섭취열량을 조사한 결과는 표3과 같다.The results of the survey on the constitution of the clinical subjects with high obesity, the dietary intake and calorie intake of diet foods during the experiment are shown in Table 3.

임상실험 대상자 현황Clinical trial subjects 성명name 연령age 체질감별설문조사 판정Constitutional Discrimination Survey Judgment 다이어트식품결식율(%)Diet Food Fasting Rate (%) 평균섭취열량(㎉/1일)Average intake calories (㎉ / 1 day) F01F01 2020 소음인(소양인)Noisemaker (Soyangin) 3.73.7 1,2921,292 F02F02 2020 소음인(소양인)Noisemaker (Soyangin) 3.33.3 677677 F03F03 2020 태음인(소양인)Taeumin (Soyang) 7.47.4 1,0201,020 F04F04 2020 소음인Noisemaker 7.47.4 1,2431,243 F05F05 2020 태음인(소양인)Taeumin (Soyang) 14.714.7 1,3631,363 M01M01 2020 태음인Lunar 7.47.4 1,0971,097 F06F06 2121 태음인Lunar 11.111.1 916916 F07F07 2121 소음인Noisemaker 13.013.0 1,2291,229 F08F08 2323 태음인(소음인)Taeumin (Noise) 7.47.4 1,0381,038 F09F09 2525 태음인Lunar 00 741741 F10F10 2626 태음인Lunar 10.010.0 1,3501,350 F11F11 2727 소양인Soyangin 3.73.7 1,1901,190 F12F12 2727 태음인(소양인)Taeumin (Soyang) 00 1,0951,095 F13F13 2929 태음인Lunar 7.47.4 1,1781,178 M02M02 2929 태음인Lunar 9.39.3 1,0991,099 F14F14 3131 태음인Lunar 9.39.3 1,3511,351 F15F15 3131 태음인Lunar 3.73.7 1,3211,321 M03M03 3232 태음인(소음인)Taeumin (Noise) 8.18.1 901901 F16F16 3333 소음인(소양인)Noisemaker (Soyangin) 00 939939 F17F17 3333 소음인(태음인)Noisemaker (Taeumin) 00 685685 F18F18 3333 소음인(태음인)Noisemaker (Taeumin) 5.65.6 1,0211,021 F19F19 3333 태음인Lunar 00 1,1771,177 F20F20 3333 태음인Lunar 9.69.6 1,0131,013 F21F21 3333 태음인Lunar 8.98.9 956956 F22F22 3434 태음인Lunar 00 1,3131,313 F23F23 3535 태음인Lunar 5.65.6 671671 F24F24 3636 태음인(소양인)Taeumin (Soyang) 9.39.3 861861 F25F25 3636 태음인Lunar 3.73.7 1,3761,376 F26F26 3838 소음인Noisemaker 5.65.6 1,2141,214 F27F27 3838 태음인(소양인)Taeumin (Soyang) 00 1,0211,021 F28F28 3939 태음인Lunar 8.58.5 1,0361,036 F29F29 3939 소음인(태음인)Noisemaker (Taeumin) 3.73.7 1,2141,214 F30F30 4040 소음인Noisemaker 5.65.6 1,2951,295 F31F31 4040 태음인(소양인)Taeumin (Soyang) 7.47.4 1,1331,133 F32F32 4141 태음인Lunar 5.65.6 1,4471,447 F33F33 4242 소음인(태음인)Noisemaker (Taeumin) 6.76.7 1,1861,186 F34F34 4444 태음인(소양인)Taeumin (Soyang) 8.18.1 1,5151,515 F35F35 5252 소음인Noisemaker 6.56.5 1,0641,064

상기의 표3에서 성명중 M은 남자, F는 여자를 나타내고, 임상대상자의 연령분포는 20대 15명, 30대 17명, 40대 5명 및 50대가 1명으로 전체 38명이 12주 동안 임상실험에 참여하였다.In Table 3, M represents male and F represents female, and the age distribution of the clinical subjects was 15 in 20s, 17 in 30s, 5 in 40s, and 1 in 50s. Participated in the experiment.

체형, 외모, 성격, 습성 식습관 및 증상 등의 요인들을 설문조사 방식으로 체질감별을 실시한 결과, 25명의 체질이 태음인으로 65.8%를 차지하였으며, 11명이 소음인으로 28.9%이었고, 나머지 1명은 소양인이었다. 그래서 비만도가 높은 임상실험 대상자들의 94.7%가 태음인 및 소음인의 체질에서 비만의 가능성이 높은 것으로 나타났다.According to the survey, factors such as body type, appearance, personality, habits, and eating habits were surveyed. As a result, 25 constitutions accounted for 65.8% of Taeumin people, 118.9% of Soinin people, and one other person. Therefore, 94.7% of the subjects with high obesity were found to have a high likelihood of obesity in their constitution.

임상실험기간 중 개인사정에 의하여 한방다이어트식품의 결식회수를 조사한 결과, 전체 84일의 실험기간 중 7명은 1회의 결식도 없었으며, 4명은 전체 270회의 복용회수 중 10%이상의 결식율을 보였으며, 6명은 5%미만의 결식을 하였고 나머지 대부분의 임상실험자들은 5∼10%의 범위에서 결식한 것으로 조사되었다. 임상실험기간 중 1일 평균 1,000㎉미만 섭취열량을 유지한 임상대상자는 전체 38명 중 9명이었으며, 1명을 제외하고 나머지 모두 1일 평균 섭취열량이 1200∼1500㎉의 범위를 유지하여 성인 1일 평균 권장열량의 1200㎉를 초과하였다. 이는 본 임상실험에서는 임상대상자들을 일전장소에 수용하면서 실험을 진행하지 않고 각자의 집에서 일상생활을 하면서 식사 및 한방다이어트식품의 섭취를 자율적으로 진행하였기 때문에 비교적 결식율과 섭취되는 평균 열량에서 조절이 어려웠을 것으로 판단된다.In the clinical trial period, the number of fastings of herbal diet foods was determined by personal circumstances. Seven of the 84 days of the trial had no fasting and four had more than 10% of the total 270 doses. Six patients had less than 5% of their diets, and most of the other researchers reported that they had eaten in the range of 5-10%. Nine out of 38 patients who had an average daily calorie intake of less than 1,000㎉ during the clinical trial period, except for one, had an average daily calorie intake in the range of 1200-1500㎉. It exceeds 1200 kPa of the daily average recommended calories. In this clinical trial, the control of diet and average calorie intake was relatively controlled because the subjects were autonomously ingested meals and diets while living in their own homes instead of carrying out the experiments while accommodating the clinical subjects. I think it was difficult.

2. 원재료의 SOD유사활성2. SOD-like activity of raw materials

표2의 원재료 배합비율에 따라서 제조된 한방다이어트식품의 원재료중 천연한방재료들을 중심으로 시험관내에서 SOD유사활성도를 분석하여 천연재료 중에 함유된 유효성분들로 인하여 발생될 수 있는 superoxide radical 및 hydroxyl radical의 소거활성에 대하여 조사한 결과는 표4와 같았다.Analysis of SOD-like activity in vitro based on natural herbal ingredients of herbal diet foods prepared according to the blending ratio of raw materials in Table 2 to determine the superoxide radical and hydroxyl radical that may be generated by active ingredients in natural ingredients. The results of scavenging activity were shown in Table 4.

한방다이어트식품의 원재료 SOD 유사활성도(%)SOD-like activity of raw materials of herbal diet foods (%) 분류Classification 원재료명Raw material name SOD 유사활성도SOD-like activity ·O2 - · O 2 - ·OHOH 주원료Main raw material 1. 다시마(昆布)Kelp 43.3343.33 25.1125.11 2. 율 무(薏苡仁)2. Yulmu 53.3353.33 9.229.22 3. 알로애3. Aloe 33.3333.33 4.224.22 4. 흑 두(黑豆)4. Black bean 56.6656.66 6.446.44 5. 당 귀(當歸)5. Party Ears 20.0020.00 36.1136.11 6. 솔 잎(松葉)6. Brush leaves 52.2352.23 76.6676.66 7. 갈 근(葛根)7. Brown root 93.3393.33 72.3372.33 8. 으 름(木通)8. 木 通 50.0050.00 69.8869.88 9. 저 령(猪笭)9. Heraldry 37.3137.31 23.0023.00 10. 맥 아(麥芽)10. Malt 80.0080.00 10.3310.33 17. 홍삼추출액(홍삼사포닌70mg/g)17. Red ginseng extract (red ginseng saponin 70mg / g) 44.7844.78 42.2242.22 18. 두 충(杜沖)18. Two Chung 8.958.95 23.3323.33 19. 가시오가피(五加皮)19. Gioniogapi (五加皮) 80.5980.59 75.1175.11 20. 매 실(梅實)20. Plums 53.3353.33 46.4346.43 21. 오미자(五味子)21. Schisandra 53.3353.33 19.8819.88 22. 죽 엽(竹葉)22. Bamboo Leaf 43.2843.28 78.2278.22 부원료Raw materials 11. 차전자皮(車前子皮)11. Tea Electronics 33.3333.33 66.1166.11 12. 백복령(白茯笭)12. Baekbokyeong (白 茯 笭) 10.0010.00 19.3319.33 23. 생녹용(生鹿茸)23. Fresh antler 36.6736.67 3.223.22 24. 맥문동(麥門冬)24. McMoon-Dong 43.2843.28 44.2244.22

* α-tocopherol SOD 유사활성도 : 32.83%(·O2 -), 80.67%(·OH)Α-tocopherol * SOD similar activity: 32.83% (· O 2 - ), 80.67% (· OH)

* Test concentration : O2 -(100ppm), ·OH (10ppm) * Test concentration: O 2 - ( 100ppm), · OH (10ppm)

SOD유사활성도를 조사하기 위한 측정허용범위내의 시험용액의 적정농도는 superoxide radical 소거능은 100ppm, hydroxyl radical 소거능은 10ppm에서 실험하였으며, radical 소거활성은 농도에 따라 증가하며, 시료들 사이에 차이를 구별할 수 있는 농도의 범위를 설정하여 측정하였다. Superoxide radical과 hydroxyl radical 소거활성은 솔잎, 갈근, 홍삼, 가시오가피, 매실 및 죽엽에서 대체로 높은 활성을 나타내었다. 그리고 천연항산화제로 널리 사용되고 있는 α-tocopherol을 대조물질로 사용하여 측정결과, superoxide radical의 소거활성은 당귀, 백복령 및 두충의 활성도는 상대적으로 낮았지만, 대부분의 원료들은 높았다. 특히 갈근 93.3%, 가시오가피 80.59%, 맥아 80.0%의 활성도를 나타내었으며, 흑두, 율무, 솔잎, 매실, 오미자 및 으름에서도 superoxide radical의 소거활성이 50%이상으로 높은 편이었다.The optimum concentration of the test solution within the allowable range for investigating SOD-like activity was tested at 100 ppm of superoxide radical scavenging ability and 10 ppm of hydroxyl radical scavenging activity, and the radical scavenging activity increased with concentration. It was measured by setting the range of concentration that can be. Superoxide radical and hydroxyl radical scavenging activities were generally high in pine needles, brown root, red ginseng, thorny red ginseng, plum and bamboo leaf. As a result of using α-tocopherol, which is widely used as a natural antioxidant, as a control, the scavenging activity of superoxide radical was relatively low, but most of the raw materials were high. In particular, it showed activity of 93.3% of root roots, 80.59% of thorny stems and 80.0% of malt, and the scavenging activity of superoxide radical was higher than 50% in black bean, yulmu, pine needles, plum, schisandra chinensis and erosion.

그러나 당귀, 저령, 두충, 백복령, 차전자피, 맥문동 및 생녹용은 superoxide radical 및 hydroxyl radical 모두에서 소거활성이 낮은 편이었다. 현재 천연항산화제로 널리 사용되고 있는 α-tocopherol은 superoxide radical 소거활성이 32.83%, hydroxyl radical의 소거활성이 80.67%로서 superoxide 소거활성에서 보다 hydroxyl radical 소거활성이 높은 것으로 나타났으나, 한방다이어트식품의 원재료로 사용된 한방재료들은 hydroxyl radical에 비하여 superoxide radical의 소거활성이 2∼3배정도 높은 것으로 나타나 인체 내에서도 SOD활성을 증가시킬 수 있을 것으로 판단되어, 본 한방다이어트식품의 복용으로 체중이 감소되는 과정에서 체지방이 분해되면서 생성되는 각종 유해물질들을 소거시키는데 도움을 줄 수 있을 것으로 판단된다.However, Angelica vulgaris, herb, worms, baekbok-ryeong, cha-e-p, mammun-dong, and live antler showed low scavenging activity in both superoxide radical and hydroxyl radical. Α-tocopherol, which is widely used as a natural antioxidant, has 32.83% superoxide radical scavenging activity and 80.67% hydroxy radical scavenging activity, showing higher hydroxyl radical scavenging activity than superoxide scavenging activity. The herbal materials used were 2 ~ 3 times higher in scavenging activity of superoxide radicals than hydroxyl radicals, which may increase the SOD activity even in the human body. It may be helpful to eliminate various harmful substances generated during decomposition.

3. 한방다이어트식품의 영양성분함량3. Nutritional Content of Herbal Diet Foods

상기의 제환방법에 따라 제조된 한방다이어트식품 중에 함유되어 있는 영양성분함량 및 SOD 유사활성도를 조사한 결과는 표5와 같았다.The results of examining the nutritional content and SOD-like activity contained in the herbal diet food prepared according to the above-mentioned refilling method are shown in Table 5.

한방다어어트식품의 영양성분함량과 SOD유사활성Nutrient Content and SOD-like Activity of Oriental Diet Foods 성 분 명Name 단 위unit 함 량content 기준치Reference value 일반성분류General Ingredients 수 분moisture g/100gg / 100g 9.519.51 조회분View minutes g/100gg / 100g 10.3410.34 가용성무질소물Soluble nitrogen-free g/100gg / 100g 65.9465.94 조단백질Crude protein g/100gg / 100g 7.597.59 60g60 g 조지방Crude fat g/100gg / 100g 2.972.97 50g50 g 조섬유Crude fiber g/100gg / 100g 3.653.65 비타민류Vitamins Viatmin AViatmin a IU/100gIU / 100g 2,991.502,991.50 700ugRE700ugRE Vitamin B1 Vitamin B 1 mg/100gmg / 100g 0.300.30 1.0mg1.0mg Vitamin B2 Vitamin B 2 mg/100gmg / 100g 3.303.30 1.2mg1.2mg Vitamin CVitamin c mg/100gmg / 100g 67.6067.60 55mg55 mg Vitamin EVitamin e mg/100gmg / 100g 8.208.20 10mgα-TE10mgα-TE 나이아신Niacin mg/100gmg / 100g 72.9072.90 13mg NE13mg NE 무기성분류Inorganic Components CaCa mg/100gmg / 100g 1,6701,670 700mg700 mg FeFe mg/100gmg / 100g 35.1035.10 15mg15 mg ZnZn mg/100gmg / 100g 1.501.50 12mg12mg SOD유사활성SOD-like activity ·O2 O 2 %% 43.2343.23 ·OHOH %% 44.2244.22

임상실험에 사용된 한방다이어트식품 중 가용성무질소물 65.94%로서 가장 많았으며, 이밖에 조단백질 7.59%. 조지방 2.97% 및 조섬유 3.65%를 나타내었다. 미량성분으로 vitamin C 67.60mg%, 나이아신 72.90mg%로서 비교적 함유량이 많은 편이었다. 인체 내에서 발생되는 superoxide radical 및 hydroxyl radical을 소거하는 SOD유사활성도를 조사한 결과 각각 43.23% 및 44.22%를 나타내어 천연항산화제로 많이 사용되는 α-tocopherol과 비교하여 볼 때, superoxide radical 소거능은 더 우수하였으나, hydroxyl radical의 소거능은 낮았다.Among the diets used in clinical trials, soluble nitrogen-free products were the most common (65.94%), and crude protein (7.59%). Crude fat was 2.97% and crude fiber 3.65%. As a minor component, vitamin C 67.60mg% and niacin 72.90mg% were relatively high in content. SOD-like activity of scavenging superoxide radicals and hydroxyl radicals in the human body was investigated, showing 43.23% and 44.22%, respectively. The scavenging ability of hydroxyl radical was low.

4. 체중변화4. Weight change

임상실험기간 90일 동안 체중감소현황을 조사한 결과는 표6과 같았다.Table 6 shows the results of weight loss during the 90 days of clinical trial.

한방다이어트 섭취기간별 체중의 변화(㎏)Changes in Body Weight by Intake Period of Herbal Diet (㎏) 성명name 섭취전Before Intake 30일30 days 60일60 days 90일90 days 감소량Decrease 감소율(%)% Reduction F01F01 7070 6969 6767 6767 33 4.34.3 F02F02 6262 5959 5959 5959 33 4.84.8 F03F03 105105 103103 103103 102102 33 2.92.9 F04F04 7070 7070 6868 6666 44 5.75.7 F05F05 7676 7575 7373 7272 44 5.35.3 M01M01 104104 101101 101101 100100 44 3.83.8 F06F06 7171 7070 6969 6666 55 7.07.0 F07F07 5656 5555 5454 5252 44 7.17.1 F08F08 6767 6767 6464 6464 33 4.54.5 F09F09 7777 7373 7070 6969 88 10.410.4 F10F10 110110 110110 110110 110110 00 00 F11F11 6666 6565 6363 6262 44 6.16.1 F12F12 6565 6262 6161 6060 55 7.77.7 F13F13 8080 7878 7878 7676 44 5.05.0 M02M02 106106 106106 106106 106106 00 00 F14F14 8686 8585 8484 8383 33 3.53.5 F15F15 7171 6969 6969 6868 33 4.24.2 M03M03 9292 9191 9191 9292 00 00 F16F16 6565 6565 6464 6262 33 4.64.6 F17F17 6565 6161 5959 5858 77 10.810.8 F18F18 6161 5959 5757 5454 77 11.511.5 F19F19 8080 7575 7070 6868 1212 15.015.0 F20F20 8282 8181 8080 8080 22 2.42.4 F21F21 7878 7777 7676 7474 44 5.15.1 F22F22 8787 8484 8383 8383 44 4.64.6 F23F23 8282 7878 7474 7474 88 9.89.8 F24F24 7373 7171 7070 6969 44 5.55.5 F25F25 6666 6565 6565 6565 1One 1.51.5 F26F26 5858 5656 5656 5454 44 6.96.9 F27F27 6969 6666 6565 6464 55 7.27.2 F28F28 100100 9797 9797 100100 00 00 F29F29 6464 6363 6161 5050 44 6.36.3 F30F30 6464 6363 6161 6060 44 6.36.3 F31F31 6464 6363 6363 6161 33 4.74.7 F32F32 7070 6969 6868 6666 44 5.75.7 F33F33 5959 5858 5858 5656 33 5.15.1 F34F34 6868 6767 6666 6363 55 7.47.4 F35F35 7272 7171 7070 6868 44 5.65.6

임상실험 전의 체중에 비하여 체중감소율이 10%이상인 대상자가 4명이었고,5∼10%의 범위에서 감소된 대상자가 18명이었으며, 9명은 5%미만의 감소율을 나타내었다. 전체대상자 38명 중 58%인 22명이 임상실험 전의 체중에 비하여 5%이상 감소된 결과를 나타내었다.Four patients had a weight loss rate of 10% or more compared to the weight before the clinical trial, 18 patients had a reduction in the range of 5-10%, and 9 had a decrease rate of less than 5%. Twenty-two (58%) of the 38 subjects lost more than 5% of their weight before the trial.

그러나 38명 중 3명은 임상실험기간 중 90일 동안에 체중의 변화가 없었다. 이들 중 1명은 체중이 92kg이었고, 2명은 100kg이상의 체중이었다. 임상대상자들의 신체적인 특성을 조사하기 위하여 설문조사방법으로 체질을 분류한 결과 임상실험에 참여한 대부분의 대상자들은 모두 태음인으로 분류되어 사상체질 중 태음인의 신체적 특성을 지닌 경우에 비만을 유발할 수 있는 빈도가 높은 것으로 추정되었다.However, 3 of 38 did not change body weight during the 90 days of the trial. One of them weighed 92 kg and two weighed more than 100 kg. In order to investigate the physical characteristics of the clinical subjects, the constitution was classified by a survey method. As a result, most of the subjects who participated in the clinical trials were classified as Taeumin. It was estimated to be high.

3. 체지방율의 변화3. Changes in body fat percentage

임상실험기간 90일 동안 체지방 감소율을 조사한 결과는 표7과 같았다.Table 7 shows the body fat reduction rate during the 90 days.

하기의 표7에서 알 수 있는 바와 같이 임상기간 중 감소된 체지방율의 변화를 조사한 결과, 15%이상 감소된 대상자는 9명이었고, 10∼15% 감소된 대상자는 10명이었다. 5∼10% 감소된 대상자는 16명이었으며, 5%미만은 전체 38명 중 2명에 뿐이었다. 그러므로 전체 대상자 38명 중 50%인 19명이 10%이상의 체지방율 감소를 나타내었다. 그래서 본 한방다이어트식품이 체지방감소로 인하여 체중을 줄일 수 있는 것으로 판단되었다.As can be seen in Table 7 below, the changes in the percent body fat decreased during the clinical period. As a result, 9 patients were reduced by more than 15%, and 10 patients were reduced by 10-15%. There were 16 subjects with a 5-10% reduction, and less than 5% were only 2 out of 38 patients. Therefore, 19% (38%) of the 38 patients showed a decrease in body fat percentage of more than 10%. Therefore, it was judged that the herbal diet food can reduce weight due to body fat reduction.

한방다이어트 섭취기간별 체지방율의 감소(%)Reduction in body fat percentage by intake period of herbal diet (%) 성명name 섭취전Before Intake 30일30 days 60일60 days 90일90 days 감소량Decrease 감소율(%)% Reduction F01F01 3838 3737 3636 3535 33 7.97.9 F02F02 3434 3131 2929 2929 55 14.714.7 F03F03 3838 3737 3737 3737 1One 2.62.6 F04F04 4141 4040 3939 3939 22 4.94.9 F05F05 4141 4141 4040 3737 44 9.89.8 M01M01 2727 2525 2424 2424 33 11.111.1 F06F06 4141 3939 3737 3434 77 17.117.1 F07F07 3131 2929 2929 2828 33 9.79.7 F08F08 3434 3434 3131 2929 55 14.714.7 F09F09 4343 4040 3838 3636 77 16.316.3 F10F10 4545 4444 4343 4242 33 6.76.7 F11F11 3434 3232 3030 2828 66 17.617.6 F12F12 3333 3232 3131 3131 22 6.16.1 F13F13 3333 3333 3232 3131 22 6.16.1 M02M02 3232 3232 3131 2929 33 9.49.4 F14F14 4242 4242 4242 3939 33 7.17.1 F15F15 4141 4141 3939 3737 44 9.89.8 M03M03 3535 3535 3434 3131 44 11.411.4 F16F16 4343 4242 4040 3737 66 14.014.0 F17F17 3737 3636 3232 3131 66 16.216.2 F18F18 4242 4040 3535 3434 88 19.019.0 F19F19 4040 3838 3737 3333 77 17.517.5 F20F20 3838 3737 3636 3333 55 13.213.2 F21F21 3737 3737 3737 3434 33 8.18.1 F22F22 4141 3939 3838 3535 66 14.614.6 F23F23 4343 3939 3636 3737 66 14.014.0 F24F24 3333 3232 3232 3030 33 9.19.1 F25F25 3030 3030 2626 2626 44 13.313.3 F26F26 3333 3232 3030 2929 44 12.112.1 F27F27 3939 3939 3838 3737 22 5.65.6 F28F28 4848 4747 4747 4545 33 6.36.3 F29F29 4040 3737 3434 3333 77 17.517.5 F30F30 4242 4040 3939 3838 44 9.59.5 F31F31 4242 3939 3636 3535 77 16.716.7 F32F32 3838 3737 3434 3131 77 18.418.4 F33F33 3939 3939 3838 3636 33 7.77.7 F34F34 3636 3535 3535 3333 33 8.38.3 F35F35 3636 3636 3636 3333 33 8.38.3

4. 근육량의 변화4. Changes in muscle mass

임상실험기간 90일 동안 임상대상자 근육량의 변화를 자동체지방분석기(Inbody)를 이용하여 조사한 결과는 표8과 같았다.The changes in the muscle mass of the subjects during the 90 days of clinical trials were analyzed using an automatic body fat analyzer (Inbody).

한방다이어트식품의 섭취기간별 근육량의 변화(kg)Changes in Muscle Mass by Intake Period of Herbal Diet Foods (kg) 성 명name 섭취전Before Intake 30일30 days 60일60 days 90일90 days 근육량변화Muscle mass changes 변화율(%)% Change F01F01 40.040.0 41.841.8 40.540.5 41.241.2 +1.2+1.2 +3.0+3.0 F02F02 39.439.4 38.438.4 39.839.8 40.440.4 +1.0+1.0 +2.5+2.5 F03F03 62.562.5 61.261.2 62.262.2 63.163.1 +0.6+0.6 +1.0+1.0 F04F04 40.040.0 39.839.8 38.038.0 38.038.0 -2.0-2.0 -5.0-5.0 F05F05 43.543.5 43.043.0 43.043.0 42.342.3 -1.3-1.3 -3.0-3.0 M01M01 72.572.5 72.272.2 72.472.4 70.370.3 -2.2-2.2 -3.0-3.0 F06F06 40.540.5 40.540.5 40.740.7 40.440.4 -0.1-0.1 -0.2-0.2 F07F07 36.036.0 36.736.7 36.136.1 37.037.0 +1.0+1.0 +2.8+2.8 F08F08 41.241.2 42.042.0 42.842.8 41.541.5 +0.3+0.3 +0.7+0.7 F09F09 41.941.9 41.941.9 41.641.6 41.941.9 00 00 F10F10 58.358.3 58.358.3 58.558.5 58.058.0 -0.3-0.3 -0.5-0.5 F11F11 40.640.6 40.640.6 41.741.7 41.741.7 +1.1+1.1 +2.7+2.7 F12F12 39.439.4 39.439.4 40.040.0 39.439.4 00 00 F13F13 48.648.6 49.449.4 50.050.0 50.250.2 +1.6+1.6 +3.3+3.3 M02M02 69.469.4 69.469.4 68.968.9 69.369.3 -0.1-0.1 -0.1-0.1 F14F14 46.046.0 46.046.0 46.446.4 47.447.4 +1.4+1.4 +3.0+3.0 F15F15 39.039.0 39.239.2 39.839.8 40.440.4 +1.4+1.4 +3.6+3.6 M03M03 56.056.0 57.257.2 57.057.0 57.557.5 +1.5+1.5 +2.7+2.7 F16F16 35.035.0 35.535.5 36.036.0 35.435.4 +0.4+0.4 +1.1+1.1 F17F17 37.337.3 37.337.3 37.437.4 38.138.1 +0.8+0.8 +2.1+2.1 F18F18 32.032.0 33.333.3 34.334.3 33.533.5 +1.5+1.5 +4.7+4.7 F19F19 46.046.0 44.144.1 41.941.9 41.941.9 -4.1-4.1 -8.9-8.9 F20F20 49.549.5 49.349.3 48.948.9 48.048.0 -1.5-1.5 -3.0-3.0 F21F21 47.047.0 46.246.2 45.145.1 45.045.0 -2.0-2.0 -4.3-4.3 F22F22 48.848.8 48.848.8 48.748.7 51.151.1 +2.3+2.3 +4.7+4.7 F23F23 45.745.7 44.944.9 44.144.1 43.243.2 -2.5-2.5 -5.5-5.5 F24F24 45.745.7 45.745.7 45.745.7 45.045.0 -0.7-0.7 -0.9-0.9 F25F25 44.244.2 42.942.9 45.245.2 44.844.8 +0.6+0.6 +1.4+1.4 F26F26 36.036.0 36.636.6 37.237.2 36.636.6 +0.6+0.6 +1.7+1.7 F27F27 38.638.6 38.238.2 37.437.4 36.936.9 -1.7-1.7 -4.4-4.4 F28F28 49.849.8 49.249.2 48.648.6 50.850.8 +1.0+1.0 +2.0+2.0 F29F29 37.537.5 37.737.7 37.937.9 37.837.8 +0.3+0.3 +0.8+0.8 F30F30 35.935.9 35.935.9 35.135.1 35.535.5 -0.4-0.4 -1.1-1.1 F31F31 36.736.7 36.736.7 37.637.6 36.536.5 -0.2-0.2 -0.5-0.5 F32F32 40.640.6 41.241.2 41.841.8 41.641.6 +1.0+1.0 +2.5+2.5 F33F33 35.035.0 34.534.5 34.034.0 34.034.0 -1.0-1.0 -2.9-2.9 F34F34 41.841.8 41.441.4 40.240.2 40.440.4 -1.4-1.4 -3.3-3.3 F35F35 43.843.8 43.843.8 42.342.3 42.042.0 -1.8-1.8 -4.1-4.1

표8에서와 같이 근육량의 변화율은 체중 및 체지방율의 변화율과 달리 매우적었다.As shown in Table 8, the rate of change of muscle mass was very small, unlike the rate of change of body weight and body fat percentage.

전체 38명 중 19명은 근육량이 소량이었지만 증가하였으며, 17명은 오히려 감소하는 경향이었다. 특히 체지방의 감소율이 큰 대상자일수록 근육량이 비교적 증가하는 경향을 나타내었으며, 체중 및 체지방율의 감소가 적은 대상자일수록 근육량은 오히려 소량 감소하였지만 그 비율은 적은 편이었다. 그래서 다이어트식품을 복용함과 동시에 운동을 병행함으로써 신체부위 중에서 체지방으로 차지하는 부분은 분해되어 감소되었고, 동시에 근육단백질이 체중에 차지하는 비율이 상대적으로 증가된 것으로 판단된다.Nineteen of the 38 patients had a small amount of muscle mass, but increased, and 17 tended to decrease. In particular, the greater the percentage of body fat reduction, the more muscle mass tended to increase, and the smaller the weight and body fat percentage, the smaller the muscle mass, but the percentage was less. Therefore, by taking diet foods and exercising at the same time, the portion of body parts of the body parts is decomposed and reduced, and at the same time, the ratio of muscle protein to body weight is considered to be relatively increased.

5. 전위, 요위의 변화5. Change in dislocations, pivot

임상실험기간 90일 동안 임상대상자의 한방다이어트식품의 섭취기간별 전위 및 요위의 변화를 조사한 결과는 하기의 표 9, 10과 같았다.During the 90 days of clinical trials, the results of investigating changes in dislocations and urine levels of the dietary diets of Korean dietary diet patients were shown in Tables 9 and 10 below.

표9에서 알 수 있는 바와 같이 임상실험 기간 중 전위의 변화는 전체 38명 중 4명은 5%이상의 감소율은 나타내었고, 26명은 5%미만의 감소율을 나타내었으나 7명은 전위의 변화가 없었다.As can be seen from Table 9, the change of dislocation during the clinical trial period showed a reduction rate of more than 5% in 38 of the total 38 patients, and a decrease of less than 5% in 26 patients, but no change in dislocation.

그리고 표10에서 알 수 있는 바와 같이, 요위의 변화율은 체중이 12kg 감소된 대상자에서 14cm의 허리둘레가 감소되어 14.5%의 감소율을 나타내었다. 그리고 8kg의 체중감소를 보인 대상자에서도 11.8cm의 허리둘레가 감소되어 역시 13.5%의 감소율을 나타내어 체중의 감소는 아랫배 부위의 체지방의 분해를 촉진하여 외부형태에서 허리둘레의 감소를 확인할 수 있었다. 14명은 5∼10%의 요위 감소율을 나타내어 전위의 변화에 비하여 체중감소에 따른 변화에 민감한 것으로 나타내었다.As can be seen in Table 10, the rate of change of the waist was reduced to 14.5% due to a decrease of 14cm waist circumference in the subject whose weight was reduced by 12kg. In the subject who showed weight loss of 8kg, the waist circumference of 11.8cm was also reduced, which also showed a decrease rate of 13.5%. Fourteen patients showed a 5-10% decrease in the level of gyrus, which was more sensitive to weight loss than the change in dislocation.

한방다이어트식품의 섭취기간별 전위의 변화(cm)Changes in Potential of Herbal Dietary Foods by Intake Period (cm) 성명name 섭취전Before Intake 30일30 days 60일60 days 90일90 days 감소량Decrease 변화율(%)% Change F01F01 94.094.0 95.095.0 94.394.3 92.492.4 -1.6-1.6 -1.7-1.7 F02F02 92.092.0 91.291.2 91.291.2 92.092.0 00 00 F03F03 112.0112.0 110.9110.9 112.4112.4 112.0112.0 00 00 F04F04 97.097.0 97.097.0 97.097.0 97.097.0 00 00 F05F05 99.099.0 99.099.0 99.599.5 98.098.0 -1.0-1.0 -1.0-1.0 M01M01 100.0100.0 98.898.8 98.298.2 98.598.5 -1.5-1.5 -1.5-1.5 F06F06 98.098.0 95.095.0 95.695.6 94.594.5 -3.5-3.5 -3.6-3.6 F07F07 81.081.0 81.581.5 81.481.4 81.581.5 +0.5+0.5 +0.6+0.6 F08F08 91.091.0 91.091.0 90.490.4 89.989.9 -1.1-1.1 -1.2-1.2 F09F09 98.098.0 97.297.2 95.095.0 95.795.7 -2.3-2.3 -2.3-2.3 F10F10 125.0125.0 125.0125.0 125.3125.3 125.0125.0 00 00 F11F11 86.286.2 86.086.0 85.885.8 84.584.5 -1.7-1.7 -2.0-2.0 F12F12 91.391.3 89.589.5 88.588.5 88.688.6 -2.7-2.7 -3.0-3.0 F13F13 108.0108.0 106.3106.3 106.4106.4 105.7105.7 -2.3-2.3 -2.1-2.1 M02M02 112.2112.2 109.0109.0 110.6110.6 110.6110.6 -1.6-1.6 -1.4-1.4 F14F14 104.0104.0 104.0104.0 104.0104.0 104.0104.0 00 00 F15F15 103.8103.8 104.1104.1 103.0103.0 101.9101.9 -1.9-1.9 -1.8-1.8 M03M03 108.0108.0 108.0108.0 108.0108.0 108.0108.0 00 00 F16F16 100.8100.8 100.8100.8 100.4100.4 97.497.4 -3.4-3.4 -3.4-3.4 F17F17 91.791.7 91.791.7 90.190.1 88.288.2 -3.5-3.5 -3.8-3.8 F18F18 95.595.5 95.095.0 93.093.0 92.092.0 -3.5-3.5 -3.7-3.7 F19F19 108.7108.7 103.0103.0 101.0101.0 98.798.7 -10.0-10.0 -9.2-9.2 F20F20 106.5106.5 107.5107.5 105.5105.5 105.2105.2 -1.3-1.3 -1.2-1.2 F21F21 103.0103.0 102.0102.0 102.0102.0 101.8101.8 -1.2-1.2 -1.2-1.2 F22F22 109.0109.0 108.5108.5 106.2106.2 106.0106.0 -3.0-3.0 -2.8-2.8 F23F23 112.6112.6 111.8111.8 107.8107.8 106.4106.4 -6.2-6.2 -5.5-5.5 F24F24 101.4101.4 99.099.0 99.599.5 98.298.2 -3.2-3.2 -3.2-3.2 F25F25 88.088.0 86.486.4 86.586.5 86.886.8 -1.2-1.2 -1.4-1.4 F26F26 92.092.0 91.091.0 91.391.3 90.890.8 -1.2-1.2 -1.3-1.3 F27F27 106.7106.7 101.5101.5 101.0101.0 98.098.0 -8.7-8.7 -8.2-8.2 F28F28 123.0123.0 122.0122.0 123.0123.0 123.0123.0 00 00 F29F29 97.097.0 96.096.0 95.895.8 95.395.3 -1.7-1.7 -1.8-1.8 F30F30 96.596.5 96.196.1 92.692.6 94.594.5 -2.0-2.0 -2.1-2.1 F31F31 97.097.0 96.396.3 95.595.5 94.294.2 -2.8-2.8 -2.9-2.9 F32F32 101.6101.6 101.4101.4 97.697.6 99.199.1 -2.5-2.5 -2.5-2.5 F33F33 96.096.0 96.096.0 93.893.8 93.793.7 -2.3-2.3 -2.4-2.4 F34F34 97.597.5 96.796.7 96.296.2 96.296.2 -1.3-1.3 -1.3-1.3 F35F35 107.2107.2 102.0102.0 102.4102.4 100.1100.1 -7.1-7.1 -6.6-6.6

한방다이어트식품의 섭취기간별 요위의 변화(cm)Changes in Levels of Intake by Herbal Dietary Diets (cm) 성명name 섭취전Before Intake 30일30 days 60일60 days 90일90 days 감소량Decrease 변화율(%)% Change F01F01 78.078.0 80.280.2 78.078.0 77.777.7 -1.3-1.3 -1.7-1.7 F02F02 82.082.0 79.079.0 80.080.0 80.080.0 -2.0-2.0 -2.4-2.4 F03F03 111.0111.0 111.0111.0 110.3110.3 111.0111.0 00 00 F04F04 90.090.0 88.088.0 86.886.8 86.086.0 -4.0-4.0 -4.4-4.4 F05F05 84.084.0 84.684.6 84.084.0 82.782.7 -1.3-1.3 -1.5-1.5 M01M01 99.099.0 94.794.7 94.094.0 94.794.7 -4.3-4.3 -4.3-4.3 F06F06 84.784.7 79.079.0 80.280.2 79.279.2 -5.5-5.5 -6.5-6.5 F07F07 69.669.6 69.569.5 68.468.4 67.067.0 -2.6-2.6 -3.7-3.7 F08F08 82.082.0 82.082.0 80.080.0 79.579.5 -2.5-2.5 -3.0-3.0 F09F09 87.587.5 80.580.5 77.777.7 75.775.7 -11.8-11.8 -13.5-13.5 F10F10 107.0107.0 107.0107.0 107.0107.0 105.9105.9 -1.1-1.1 -1.0-1.0 F11F11 76.076.0 75.075.0 74.274.2 72.072.0 -4.0-4.0 -5.3-5.3 F12F12 78.678.6 77.377.3 77.877.8 75.275.2 -3.4-3.4 -4.3-4.3 F13F13 95.495.4 91.791.7 91.291.2 89.489.4 -6.0-6.0 -6.3-6.3 M02M02 109.0109.0 108.7108.7 106.5106.5 106.6106.6 -2.4-2.4 -2.2-2.2 F14F14 110.0110.0 110.0110.0 110.0110.0 108.8108.8 -1.2-1.2 -1.1-1.1 F15F15 92.092.0 89.589.5 88.588.5 86.086.0 -6.0-6.0 -6.5-6.5 M03M03 100.0100.0 100.0100.0 98.598.5 98.298.2 -1.8-1.8 -1.8-1.8 F16F16 90.790.7 90.290.2 88.588.5 84.084.0 -6.7-6.7 -7.4-7.4 F17F17 77.277.2 75.075.0 72.372.3 70.370.3 -6.9-6.9 -8.9-8.9 F18F18 81.981.9 79.679.6 77.877.8 75.475.4 -6.5-6.5 -7.9-7.9 F19F19 96.396.3 92.892.8 84.184.1 82.382.3 -14.0-14.0 -14.5-14.5 F20F20 90.090.0 90.090.0 89.889.8 88.288.2 -1.8-1.8 -2.0-2.0 F21F21 90.490.4 90.090.0 89.589.5 89.289.2 -1.2-1.2 -1.3-1.3 F22F22 93.093.0 91.291.2 89.589.5 88.788.7 -4.3-4.3 -4.6-4.6 F23F23 98.398.3 94.694.6 92.092.0 89.589.5 -8.8-8.8 -9.0-9.0 F24F24 85.285.2 82.082.0 83.383.3 80.980.9 -4.3-4.3 -5.0-5.0 F25F25 81.381.3 81.381.3 79.779.7 79.079.0 -2.3-2.3 -2.8-2.8 F26F26 77.077.0 76.076.0 77.077.0 75.875.8 -1.2-1.2 -1.6-1.6 F27F27 90.490.4 91.291.2 85.085.0 82.582.5 -7.9-7.9 -8.7-8.7 F28F28 112.2112.2 111.0111.0 111.2111.2 110.8110.8 -1.4-1.4 -1.2-1.2 F29F29 81.081.0 80.080.0 79.179.1 75.875.8 -5.2-5.2 -6.4-6.4 F30F30 89.089.0 84.084.0 81.381.3 80.580.5 -8.5-8.5 -9.6-9.6 F31F31 87.087.0 86.686.6 85.885.8 85.685.6 -1.4-1.4 -1.6-1.6 F32F32 92.592.5 90.590.5 85.685.6 85.585.5 -7.0-7.0 -7.6-7.6 F33F33 85.285.2 85.785.7 84.384.3 84.084.0 -1.2-1.2 -1.4-1.4 F34F34 89.089.0 87.787.7 87.587.5 86.786.7 -2.3-2.3 -2.6-2.6 F35F35 90.590.5 84.584.5 87.287.2 83.083.0 -7.5-7.5 -8.3-8.3

6. 중성지방의 변화6. Changes in Triglycerides

임상실험기간 중 중성지방함량의 변화를 조사한 결과는 표11과 같았다.Table 11 shows the changes in triglyceride content during the clinical trials.

한방다이어트식품의 섭취기간별 혈액 중 중성지방 함량의 변화(㎎/㎗)Changes in Triglyceride Contents of Blood by Intake Period of Herbal Diet Foods (mg / ㎗) 성명name 섭취전Before Intake 30일30 days 60일60 days 90일90 days 감소량Decrease 감소율(%)% Reduction F01F01 9393 8080 8282 6565 2828 -30.1-30.1 F02F02 159159 6262 125125 6161 -98-98 -61.6-61.6 F03F03 340340 323323 356356 345345 +5+5 +1.5+1.5 F04F04 155155 114114 168168 120120 -35-35 -22.6-22.6 F05F05 209209 200200 199199 175175 -34-34 -16.7-16.7 M01M01 340340 164164 160160 147147 -193-193 -56.8-56.8 F06F06 256256 124124 179179 108108 -148-148 -57.9-57.9 F07F07 7575 6767 7373 6060 -15-15 -20.0-20.0 F08F08 8080 7979 7878 7373 -7-7 -8.8-8.8 F09F09 170170 6565 7878 8585 -85-85 -50.0-50.0 F10F10 160160 185185 116116 116116 -44-44 -27.5-27.5 F11F11 6969 5353 6363 5252 -17-17 -24.6-24.6 F12F12 168168 112112 160160 131131 -37-37 -22.0-22.0 F13F13 118118 110110 110110 106106 -12-12 -10.2-10.2 M02M02 210210 168168 233233 236236 +26+26 +12.4+12.4 F14F14 7676 7676 7474 7474 -2-2 -2.6-2.6 F15F15 171171 9191 184184 9797 -74-74 -43.3-43.3 M03M03 116116 8888 178178 117117 +1+1 +0.9+0.9 F16F16 458458 456456 469469 460460 +2+2 +0.4+0.4 F17F17 9898 4646 8484 6262 -36-36 -36.7-36.7 F18F18 103103 9090 7575 7272 -31-31 -30.1-30.1 F19F19 156156 6767 7575 8282 -74-74 -47.4-47.4 F20F20 124124 9696 8686 7575 -49-49 -39.5-39.5 F21F21 185185 7474 121121 113113 -72-72 -38.9-38.9 F22F22 174174 105105 206206 150150 -24-24 -13.8-13.8 F23F23 144144 7272 7070 6565 -79-79 -54.9-54.9 F24F24 133133 156156 132132 132132 -1-One -0.8-0.8 F25F25 157157 153153 149149 103103 -54-54 -34.4-34.4 F26F26 104104 9292 9292 8585 -19-19 -18.3-18.3 F27F27 150150 6666 9090 9999 -51-51 -34.0-34.0 F28F28 7171 7171 107107 9595 +24+24 +33.8+33.8 F29F29 146146 8383 174174 102102 -44-44 -30.1-30.1 F30F30 125125 122122 118118 110110 -15-15 -12.0-12.0 F31F31 171171 9696 114114 143143 -28-28 -16.4-16.4 F32F32 170170 195195 398398 171171 +1+1 +0.6+0.6 F33F33 9191 7474 111111 6666 -25-25 -27.5-27.5 F34F34 184184 153153 242242 157157 -27-27 -14.7-14.7 F35F35 183183 180180 161161 160160 -23-23 -12.6-12.6

*정상치 : 40∼200㎎/㎗* Normal value: 40 ~ 200mg / ㎗

임상실험기간 중 혈액 중 중성지방 함량의 변화를 조사한 결과, 중성지방함량의 감소율이 50%이상인 대상자는 5명이었으며, 10명은 30∼49%의 감소율을 나타내었고,14명은 10∼29%의 중성지방 함량의 감소율을 나타내어, 전체 38명 중 77%를 차지하는 29명이 10%이상의 혈액 중 중성지방함량의 감소율을 나타내었으나, 16%를 차지하는 6명의 경우에는 소량이었지만 오히려 증가하는 경향을 나타내었다. 그래서 체지방 함량을 증가시킬 수 있는 혈액 중 중성지방 함량의 감소에 좋은 효능이 있는 것으로 판단되었다.As a result of examining the change of triglyceride content in the blood during the clinical trials, 5 subjects showed a decrease in triglyceride content of 50% or more, 10 patients showed a reduction of 30-49%, and 14 patients 10-29% neutral. Reduction of fat content was found in 29 patients (77% of the total 38), but the percentage of triglycerides in the blood of 10% or more was decreased. Therefore, it was judged to have a good effect on the reduction of triglyceride content in the blood which can increase the body fat content.

7. 총 콜레스테롤의 변화7. Changes in Total Cholesterol

임상실험기간 혈액 중 콜레스테롤 함량의 변화를 조사한 결과는 표 12와 같았다.Table 12 shows the changes in the cholesterol content in the blood during the clinical trials.

임상대상자들의 혈액 중 총 콜레스테롤의 함량을 분석한 결과, 30%이상 감소율을 나타낸 대상자가 2명이었으며, 9명은 20∼29%의 감소율을 나타내었으며, 전체 대상자의 37%를 차지하는 14명은 10∼19%의 감소율을 나타내어 전체 38명의 임상대상자 중에서 66%를 차지하는 25명이 10%이상의 총 콜레스테롤 함량의 감소율을 나나내었으나, 단지 1명만이 소량이었지만 증가하는 경향을 나타내어, 본 한방다이어트 제품은 혈액 중 총 콜레스테롤의 함량을 감소시키는데 효과가 좋은 것으로 나타났다.As a result of analyzing the total cholesterol content in the blood of the clinical subjects, 2 patients showed a reduction rate of more than 30%, 9 patients showed a reduction rate of 20-29%, and 14 patients accounted for 37% of the total 10-19 25% of total 38 clinical subjects showed a decrease rate of 25%, resulting in a decrease in total cholesterol content of more than 10%, but only 1 showed a small but increasing trend. It has been shown to be effective in reducing the content of cholesterol.

한방다이어트식품의 섭취기간별 혈액 중 총 콜레스테롤 함량변화(㎎/㎗)Changes in Total Cholesterol Content in Blood by Intake Period of Herbal Diet Foods (mg / ㎗) 성명name 섭취전Before Intake 30일30 days 60일60 days 90일90 days 감소량Decrease 감소율(%)% Reduction F01F01 221221 204204 220220 203203 -18-18 -8.1-8.1 F02F02 209209 204204 192192 163163 -46-46 -22.0-22.0 F03F03 229229 220220 223223 227227 -2-2 -0.9-0.9 F04F04 215215 211211 208208 200200 -15-15 -7.0-7.0 F05F05 224224 230230 233233 196196 -28-28 -12.5-12.5 M01M01 226226 209209 207207 180180 -46-46 -20.4-20.4 F06F06 242242 199199 223223 200200 -42-42 -17.4-17.4 F07F07 206206 213213 166166 167167 -39-39 -18.9-18.9 F08F08 168168 189189 205205 161161 -7-7 -4.2-4.2 F09F09 224224 188188 194194 171171 -53-53 -23.7-23.7 F10F10 243243 210210 244244 215215 -28-28 -11.5-11.5 F11F11 159159 166166 178178 158158 -1-One -0.6-0.6 F12F12 199199 164164 196196 190190 -9-9 -4.5-4.5 F13F13 212212 163163 159159 150150 -62-62 -29.2-29.2 M02M02 261261 218218 225225 220220 -41-41 -15.7-15.7 F14F14 201201 235235 225225 230230 -29-29 -14.4-14.4 F15F15 214214 191191 201201 195195 -19-19 -8.9-8.9 M03M03 184184 203203 216216 177177 -7-7 -3.8-3.8 F16F16 495495 336336 316316 288288 -207-207 -41.8-41.8 F17F17 221221 160160 215215 177177 -44-44 -19.9-19.9 F18F18 206206 153153 207207 198198 -8-8 -3.9-3.9 F19F19 224224 147147 182182 172172 -52-52 -23.2-23.2 F20F20 207207 192192 188188 185185 -22-22 -10.6-10.6 F21F21 194194 168168 217217 168168 -26-26 -13.4-13.4 F22F22 186186 175175 232232 211211 -25-25 -13.4-13.4 F23F23 235235 219219 205205 185185 -50-50 -21.3-21.3 F24F24 249249 185185 201201 200200 -49-49 -19.7-19.7 F25F25 190190 158158 180180 148148 -42-42 -22.1-22.1 F26F26 234234 187187 231231 167167 -67-67 -28.6-28.6 F27F27 253253 201201 263263 222222 -31-31 -12.3-12.3 F28F28 163163 155155 167167 165165 +2+2 +1.2+1.2 F29F29 211211 172172 225225 187187 -24-24 -11.3-11.3 F30F30 284284 203203 209209 203203 -81-81 -28.5-28.5 F31F31 260260 216216 249249 256256 -4-4 -1.5-1.5 F32F32 291291 256256 297297 290290 -1-One -0.3-0.3 F33F33 221221 176176 216216 103103 -118-118 -53.4-53.4 F34F34 278278 204204 272272 258258 -20-20 -7.2-7.2 F35F35 264264 255255 324324 224224 -40-40 -15.2-15.2

* 정상치 : 230㎎/㎗ 이하* Normal value: 230mg / ㎗ or less

8. 혈압의 변화8. Change of blood pressure

임상실험기간 중에 한방다이어트식품을 섭취함에 따라 발생할 수 있는 혈압의 변화를 조사한 결과는 표13과 같았다.Table 13 shows the changes in blood pressure that may occur as a result of ingesting herbal diet foods during clinical trials.

한방다이어트식품의 섭취기간별 혈압의 변화Blood Pressure Variation by Intake Period of Herbal Diet Foods 성명name 섭취전Before Intake 30일30 days 60일60 days 90일90 days 변화change 최고Best 최저lowest 최고Best 최저lowest 최고Best 최저lowest 최고Best 최저lowest 최고Best 최저lowest F01F01 120120 7070 124124 6464 111111 6868 116116 6666 -4-4 -4-4 F02F02 137137 8888 127127 8888 134134 8181 112112 8888 -25-25 00 F03F03 161161 8686 149149 9999 137137 8989 164164 107107 +3+3 +21+21 F04F04 119119 8282 120120 7676 116116 6363 116116 7070 -3-3 -12-12 F05F05 120120 6464 116116 7676 118118 7373 118118 7070 -2-2 +6+6 M01M01 167167 9797 143143 8484 154154 8888 149149 8484 -18-18 -13-13 F06F06 130130 9292 135135 8585 137137 9090 122122 8383 -8-8 -9-9 F07F07 130130 9090 120120 8080 130130 9090 120120 8080 -10-10 -10-10 F08F08 106106 7474 101101 7474 114114 6464 111111 7070 +5+5 -4-4 F09F09 140140 8888 124124 8080 121121 7777 106106 7272 -34-34 -16-16 F10F10 144144 104104 140140 9090 144144 8484 140140 8585 -4-4 -19-19 F11F11 128128 8585 118118 8888 105105 7070 112112 7777 -16-16 -8-8 F12F12 136136 9393 126126 7676 126126 7070 124124 7373 -12-12 -20-20 F13F13 136136 9292 122122 8686 127127 8282 125125 8585 -11-11 -7-7 M02M02 145145 8585 140140 8787 149149 7979 139139 6464 -6-6 -21-21 F14F14 130130 9595 132132 9090 128128 8989 130130 9090 00 -5-5 F15F15 122122 8080 120120 8282 124124 6969 112112 7070 -10-10 -10-10 M03M03 145145 9393 143143 9090 145145 8787 140140 9797 -5-5 +4+4 F16F16 129129 9090 119119 8989 119119 8080 130130 8686 +1+1 -4-4 F17F17 130130 8585 120120 7474 108108 6363 107107 7474 -23-23 -11-11 F18F18 113113 8080 114114 8080 127127 7575 105105 6767 -8-8 -13-13 F19F19 137137 9696 135135 100100 116116 7777 116116 8080 -21-21 -16-16 F20F20 104104 8888 128128 8080 124124 7777 112112 8080 +8+8 -8-8 F21F21 128128 8282 122122 8484 120120 8080 116116 8181 -12-12 -1-One F22F22 136136 8585 134134 8484 128128 7878 138138 8484 +2+2 -1-One F23F23 152152 100100 134134 8888 114114 7979 112112 6969 -40-40 -31-31 F24F24 138138 9595 140140 9999 134134 8484 135135 8585 -3-3 -10-10 F25F25 112112 8686 121121 8787 127127 8080 126126 8888 +14+14 +2+2 F26F26 126126 9292 114114 8080 111111 7272 109109 8686 -17-17 -6-6 F27F27 132132 8989 139139 8686 111111 5858 124124 7373 -8-8 -16-16 F28F28 141141 9696 148148 8989 137137 7777 112112 7474 -29-29 -22-22 F29F29 136136 8787 140140 9191 123123 8080 120120 7272 -16-16 -15-15 F30F30 136136 8585 135135 8787 129129 8282 123123 8686 -13-13 +1+1 F31F31 136136 9696 120120 8383 143143 8888 116116 7676 -20-20 -20-20 F32F32 133133 8484 123123 7777 144144 8888 119119 6666 -14-14 -18-18 F33F33 130130 8080 132132 8888 120120 7777 130130 8585 00 +5+5 F34F34 151151 9595 147147 8282 143143 8282 123123 8383 -28-28 -12-12 F35F35 156156 9393 136136 8888 129129 8181 129129 8181 -27-27 -12-12

한방다이어트식품을 섭취하기 전에는 전체 38명의 대상자들 중에서 최고혈압이 130이상인 대상자는 26명이었으며, 최저혈압이 90이상인 대상자는 17명이었다.비만도가 높은 대상자들의 혈압은 정상치 보다 높은 경향을 보였다. 임상실험기간 중 한방다이어트식품을 복용함에 따라 최고혈압이 130인 이상인 대상자는 9명으로 감소하였으며, 최저혈압이 90이상인 대상자는 3명으로 감소되었다. 그러나 임상실험 대상자 중 2명은 오히려 소량이었지만 증가하였다. 그러나 전체적으로 임상실험을 시행하기 전에는 대체로 혈압이 정상치 보다 높았지만, 한방다이어트식품을 섭취함에 따라 체지방 분해 및 체중감소로 인하여 혈압이 정상으로 회복될 수 있음을 확인할 수 있었다.Before taking herbal diets, 26 patients had a peak blood pressure of 130 or higher, and 17 patients had a minimum blood pressure of 90 or higher. The blood pressure of patients with high obesity tended to be higher than normal. The duration of clinical trials decreased the number of subjects with a peak blood pressure of 130 or more to 9 and the number of patients with a minimum blood pressure of 90 or more. Two of the subjects, however, increased, although in small quantities. However, although the blood pressure was generally higher than the normal level before the clinical trial, the blood pressure could be restored to normal due to the body fat decomposition and weight loss.

9. 간기능의 변화9. Changes in liver function

본 임상실험에 사용된 각종 한방생약재들은 인체 내의 숙변을 제거하여 생리작용을 정상화하고, 체지방을 분해하여 체중을 감소하기 위한 한방자원들로 구성되어 있다. 그러나 임상실험기간 중 식이조절과 운동요법을 병행하여 간기능이 저하되어 건강유지에 대한 부작용을 초래할 수 있는지를 확인하기 위하여 한방다이어트식품의 섭취기간 중 1개월 간격으로 혈액을 채취하여 간기능에 대한 영향을 조사하기 위하여 GOT, GPT값의 변화를 조사한 결과는 표14와 같았다.Various herbal medicines used in this clinical trial are composed of herbal resources to remove stool in the human body to normalize physiological action and break down body fat to reduce weight. However, in order to confirm whether liver function is deteriorated due to the combination of dietary control and exercise therapy during the clinical trial period, blood is collected at intervals of one month during the period of intake of herbal diet foods for liver function. The results of investigating changes in GOT and GPT values were as shown in Table 14.

간기능을 나타내는 지표인 GOT, GPT의 성인에 대한 정상치는 각각 40U/L이하 및 35U/L이다. 임상실험대상자 38명 중 GOT, GPT의 값이 증가한 경우는 9명이었으나 이들 중에서 4명은 정상값 보다 높은 수치를 나타내었지만 이들은 임상실험 전의 간기능 값이 정상값 보다 훨씬 높은 상태를 나타내는 경우이었다.Normal values for GOT and GPT, which are indicators of liver function, are below 40 U / L and 35 U / L, respectively. Nine cases of GOT and GPT were increased in nine of the 38 subjects, but four of them showed higher values than normal values. However, these patients had significantly higher liver function values than normal values.

한방다이어트식품의 섭취기간별 간기능(GOT, GPT)의 변화 (U/L)Changes in liver function (GOT, GPT) by intake period of herbal diet foods (U / L) 성명name 섭취전Before Intake 30일30 days 60일60 days 90일90 days 변화change GOTGOT GPTGPT GOTGOT GPTGPT GOTGOT GPTGPT GOTGOT GPTGPT GOTGOT GPTGPT F01F01 2222 1111 1414 1111 2222 1212 2424 1717 +2+2 +6+6 F02F02 2929 3131 1919 1414 2222 1414 2626 1818 -3-3 -13-13 F03F03 5050 4949 2727 2626 3535 5555 5555 4343 +5+5 -6-6 F04F04 3636 2525 2121 1515 1616 1010 1717 1010 -19-19 -15-15 F05F05 1717 2020 3636 2929 1313 1313 1515 1313 -2-2 -7-7 M01M01 5050 4949 3030 3838 2525 4242 5151 5151 +1+1 +2+2 F06F06 2929 2121 1717 1818 1818 1515 1111 1414 -18-18 -7-7 F07F07 2121 1111 2020 1414 4141 2323 1212 1616 -9-9 +5+5 F08F08 2323 1212 1616 1414 2727 1515 2121 1616 -2-2 +4+4 F09F09 2626 2525 1717 1111 1919 1111 2929 1212 +3+3 -13-13 F10F10 7878 9393 4242 5353 4040 4747 4242 4848 -36-36 -45-45 F11F11 1818 1414 2323 1414 2020 1616 3434 2424 +16+16 +10+10 F12F12 3939 3636 1717 1515 1515 1313 2020 2121 -19-19 -15-15 F13F13 2525 1818 1818 1717 1616 1919 1717 1919 -8-8 +1+1 M02M02 3434 3737 2121 3333 2525 3030 2424 4141 -10-10 +4+4 F14F14 1717 1010 1414 1010 1616 1212 1616 1010 -1-One 00 F15F15 1313 1111 1111 1010 2121 1212 99 1010 -4-4 -1-One M03M03 6363 4545 5151 5858 4343 8888 4646 3737 -17-17 -8-8 F16F16 3535 3434 2020 2222 2323 2121 3030 1919 -5-5 -15-15 F17F17 2020 1010 2626 1818 3737 3232 3030 1717 +10+10 +7+7 F18F18 2020 1515 2222 1717 2424 1515 1818 1414 -2-2 -1-One F19F19 1717 1515 1414 1616 1919 1818 1818 1616 +1+1 +1+1 F20F20 1818 1212 1919 1414 2121 1212 1616 1616 -2-2 +4+4 F21F21 2525 3030 1515 1414 2020 1414 1616 1515 -9-9 -15-15 F22F22 1919 1818 1717 1616 1818 1717 2020 1616 +1+1 -2-2 F23F23 2323 1919 1717 1616 2626 1818 1818 1414 -5-5 -5-5 F24F24 1515 1111 1515 1212 1818 1212 1818 1212 +3+3 +1+1 F25F25 1919 1616 2222 2020 2020 1717 3131 1616 +12+12 00 F26F26 1919 1313 1414 1010 4747 2525 1919 1515 00 +2+2 F27F27 2525 1616 2525 1818 2828 2020 2727 1818 +2+2 +2+2 F28F28 2121 1515 2323 1717 2828 1818 3030 2020 +9+9 +5+5 F29F29 3030 1111 1515 1010 1313 1717 2121 1111 +9+9 00 F30F30 2222 2929 2121 2727 2222 3131 1818 2020 -4-4 -9-9 F31F31 2222 2121 2121 2828 2424 2323 2222 2222 00 +1+1 F32F32 2121 1717 1616 1414 2626 2020 2222 1515 +1+1 -2-2 F33F33 2727 2424 2727 2424 2929 2525 2525 2424 -2-2 00 F34F34 3636 3434 1919 2424 2626 2222 2121 2222 -15-15 -12-12 F35F35 3232 2323 2323 2020 2525 2020 2525 2121 -7-7 -2-2

* 정상치 : GOT 40U/L 이하, GPT 35U/L 이하* Normal value: GOT 40U / L or less, GPT 35U / L or less

나머지 5명의 최종 값은 실험이전보다는 조금 상승하였지만 GOT, GPT 모두 정상수치 범위 내에 속하였다. 그리고 임상대상자들 중 16명은 임상실험 시작 전보다 대상자에 따라 다소 차이는 인정되었지만 감소하는 경향을 보여 본 한방다이어트식품을 섭취함에 따라 간기능을 손상시키는 현상은 발견되지 않았다.The final values of the remaining five were slightly higher than before, but both GOT and GPT were within the normal range. In 16 of the subjects, the difference was recognized, but tended to decrease according to the subjects before the start of the clinical trial.

10. 혈색소의 변화10. Changes in hemoglobin

임상실험기간 중 식이조절과 운동요법을 병행하여 혈색소가 감소되어 건강유지에 대한 부작용을 초래할 수 있을 것으로 예상되어 한방다이어트식품의 섭취기간 중에 1개월 간격으로 혈액을 채취하여 혈색소의 함량을 조사한 결과는 표 15와 같았다.Hemoglobin decreased during dietary trials and exercise therapy in parallel, which may cause side effects on health maintenance. It was as Table 15.

하기의 표15에서 알 수 있는 바와 같이 임상실험기간 중 전체 38명 중 20명은 소량이었지만 혈색소 함량이 증가되었으며, 14명은 감소되는 경향을 보였다. 그러나 혈색소의 함량이 증가 혹은 감소된 대상자들이라도 정상치의 범위인 남자의 13∼16.5g/㎗, 여자의 12∼15.5g/㎗의 범위에 속하여 감소로 인한 건강상태의 악화를 유발하지 않을 것으로 판단되었으며, 임상대상자 중에서 3명은 한방다이어트식품의 섭취 전후의 모두에서 정상치의 범위에 미달하였으므로 한방다이어트식품의 복용으로 인하여 혈색소의 영향은 미미할 것으로 예상되었다.As can be seen in Table 15 below, 20 of the 38 patients had a small amount during the clinical trial period, but the hemoglobin content was increased, and 14 showed a tendency to decrease. However, even those subjects with increased or decreased hemoglobin content fall within the normal range of 13-16.5g / dl for men and 12-15.5g / dl for women and will not cause deterioration of health status due to reduction. Three of the subjects were below normal ranges before and after intake of herbal diet foods. Therefore, hemoglobin was expected to be insignificant due to the use of herbal diet foods.

한방다이어트식품의 섭취기간에 따른 혈색소 함량의 변화(g/㎗)Changes in Hemoglobin Content According to Intake Period of Herbal Diet Foods (g / ㎗) 성명name 섭취전Before Intake 30일30 days 60일60 days 90일90 days 변화량Change F01F01 13.313.3 13.413.4 13.213.2 12.912.9 -0.4-0.4 F02F02 15.315.3 15.215.2 14.314.3 13.913.9 -1.4-1.4 F03F03 17.217.2 16.716.7 17.617.6 16.416.4 -0.8-0.8 F04F04 13.713.7 13.213.2 13.813.8 13.813.8 +0.1+0.1 F05F05 15.615.6 15.015.0 14.114.1 14.514.5 -1.1-1.1 M01M01 17.217.2 15.815.8 15.115.1 15.415.4 -1.8-1.8 F06F06 11.911.9 11.111.1 11.011.0 11.111.1 -0.8-0.8 F07F07 14.414.4 13.913.9 14.314.3 14.014.0 -0.4-0.4 F08F08 12.512.5 12.712.7 12.312.3 12.712.7 +0.2+0.2 F09F09 13.913.9 13.913.9 13.713.7 13.813.8 -0.1-0.1 F10F10 15.515.5 14.514.5 13.613.6 14.014.0 -1.5-1.5 F11F11 13.513.5 13.313.3 12.712.7 13.013.0 -0.5-0.5 F12F12 13.213.2 13.213.2 13.513.5 13.313.3 +0.1+0.1 F13F13 13.913.9 13.913.9 13.913.9 14.014.0 +0.1+0.1 M02M02 16.516.5 16.916.9 16.216.2 16.716.7 +0.2+0.2 F14F14 12.512.5 13.313.3 13.513.5 13.113.1 +0.6+0.6 F15F15 13.013.0 13.113.1 12.712.7 14.514.5 +1.5+1.5 M03M03 15.415.4 15.215.2 15.915.9 16.316.3 +0.9+0.9 F16F16 12.112.1 13.113.1 14.114.1 14.314.3 +2.2+2.2 F17F17 12.512.5 12.612.6 14.014.0 13.413.4 +0.9+0.9 F18F18 13.013.0 13.313.3 13.313.3 13.013.0 00 F19F19 13.113.1 13.113.1 13.913.9 13.113.1 00 F20F20 13.013.0 13.113.1 14.114.1 13.713.7 +0.7+0.7 F21F21 13.013.0 13.113.1 13.313.3 12.612.6 -0.4-0.4 F22F22 12.212.2 12.212.2 13.013.0 12.312.3 +0.1+0.1 F23F23 12.512.5 12.512.5 12.812.8 12.912.9 +0.4+0.4 F24F24 13.413.4 13.413.4 12.512.5 13.013.0 -0.4-0.4 F25F25 13.413.4 13.013.0 12.812.8 13.113.1 -0.3-0.3 F26F26 12.412.4 12.412.4 13.013.0 13.713.7 +1.3+1.3 F27F27 13.613.6 13.613.6 13.313.3 13.913.9 +0.3+0.3 F28F28 11.011.0 11.011.0 10.610.6 11.011.0 00 F29F29 14.314.3 14.314.3 14.514.5 13.713.7 -0.6-0.6 F30F30 13.413.4 13.413.4 13.513.5 13.813.8 +0.4+0.4 F31F31 12.812.8 12.712.7 12.912.9 13.013.0 +0.2+0.2 F32F32 13.413.4 13.413.4 14.114.1 13.613.6 +0.2+0.2 F33F33 10.510.5 10.310.3 10.710.7 10.710.7 +0.2+0.2 F34F34 14.414.4 14.314.3 14.714.7 14.014.0 -0.4-0.4 F35F35 14.014.0 14.014.0 14.114.1 14.114.1 +0.1+0.1

* 정상치 : 남 13∼16.5g/㎗, 여 12∼15.5g/㎗* Normal value: Male 13-16.5g / ㎗, Female 12-15.5g / ㎗

11. 혈액 중 당질함량의 변화11. Changes in sugar content in the blood

한방다이어트식품의 섭취기간 중에 1개월 간격으로 혈액을 채취하여 당질의함량을 조사한 결과는 표16과 같았다.As a result of examining blood sugar content by taking blood at intervals of one month during the intake period of herbal diet foods, the results are shown in Table 16.

한방다이어트식품의 섭취기간별 혈액 중 당질함량의 변화(㎎/㎗)Changes in Glucose Content in Blood by Intake Period of Herbal Diet Foods (mg / ㎗) 성명name 섭취전Before Intake 30일30 days 60일60 days 90일90 days 변화량Change F01F01 8989 8989 9696 100100 +11+11 F02F02 7373 9292 101101 7878 +5+5 F03F03 8080 119119 9494 9090 +10+10 F04F04 7575 8585 8484 8585 +10+10 F05F05 110110 9393 8484 9090 -20-20 M01M01 8080 116116 108108 7878 -2-2 F06F06 7676 131131 109109 9494 +18+18 F07F07 9696 9696 8181 9595 -1-One F08F08 7878 7575 9393 7878 00 F09F09 104104 9090 102102 115115 +11+11 F10F10 9797 120120 9999 9595 -2-2 F11F11 8080 8585 102102 7777 -3-3 F12F12 9090 112112 102102 114114 +24+24 F13F13 108108 8585 8787 9090 -18-18 M02M02 9292 6969 101101 113113 +21+21 F14F14 116116 9595 102102 113113 -3-3 F15F15 8888 8282 8787 107107 +19+19 M03M03 173173 139139 169169 118118 -55-55 F16F16 128128 9191 9696 8484 -44-44 F17F17 8181 7474 9090 105105 +24+24 F18F18 8282 8282 109109 107107 +25+25 F19F19 8383 7373 9797 104104 +21+21 F20F20 9494 7878 8686 9191 -3-3 F21F21 8383 9898 9393 104104 +21+21 F22F22 8585 7676 8888 119119 +34+34 F23F23 8686 7878 9696 103103 +17+17 F24F24 8080 7171 109109 8585 +5+5 F25F25 9090 121121 117117 8787 -3-3 F26F26 103103 8282 9696 104104 +1+1 F27F27 8383 7070 9292 8181 -2-2 F28F28 8383 7676 8383 9898 +15+15 F29F29 9797 7979 110110 116116 +19+19 F30F30 8686 8585 8383 102102 +16+16 F31F31 9090 8282 7676 102102 +12+12 F32F32 9898 8585 101101 107107 +9+9 F33F33 163163 9292 9797 111111 -52-52 F34F34 9090 8080 9999 118118 +28+28 F35F35 106106 7777 109109 105105 -1-One

* 정상치 : 70∼110㎎/㎗* Normal value: 70 ~ 110㎎ / ㎗

전체 임상대상자 중에서 23명은 혈액 중 당질함량이 증가하였으며, 14명은감소하였다. 그러나 증가 혹은 감소된 대상자들의 대부분은 정상치인 70∼110㎎/㎗의 범위에 속하였으나, 그중 5명은 임상실험기간 중 혈액 중 당질의 함량이 증가되어 정상치 보다 높은 당질의 함량을 보였고, 2명은 실험 전에 비하여 감소되었지만 정상치의 당질함량에 비하여 높았다.Twenty-three of the total subjects had an increase in blood sugar content and 14 had a decrease. However, most of the increased or decreased subjects belonged to the normal range of 70-110mg / dL, but 5 of them showed higher sugar content than normal due to increased blood sugar content during the clinical trial period. It was reduced compared to the previous, but higher than the normal sugar content.

그래서 한방다이어트식품의 섭취가 혈액 중 당질의 함량에 미치는 영향은 매우 적을 것으로 판단되었으며, 오히려 혈액채취 당일의 식후 경과시간과 섭취된 음식의 메뉴의 종류에 따라서 크게 영향을 받은 것으로 판단되었다.Therefore, it was judged that the effect of the intake of herbal diet foods on the content of sugar in the blood was very small, but rather it was greatly influenced by the post-prandial elapsed time on the day of blood collection and the type of food intake.

12. 혈액 중 단백질함량의 변화12. Changes in Protein Content in Blood

임상실험기간 중 1개월마다 혈액을 채취하여 단백질 함량의 변화를 조사한 결과는 표17과 같았다.The blood samples were collected every month during the clinical trial and the changes in protein content were shown in Table 17.

표17에서 알 수 있는 바와 같이 임상실험기간 중 혈액 중 단백질의 함량을 조사한 결과는 임상실험 대상자 38명 중 26명은 약간 증가하였으며, 10명은 증가하였다. 그러나 임상대상자 전원이 한방다이어트식품의 섭취 전, 후에 모두 정상치의 범위인 6.0∼8.5g/㎗의 범위에 속하였다.As can be seen from Table 17, 26 of 38 clinical trials showed a slight increase in blood protein content during the clinical trial, and 10 increased. However, all the subjects were in the range of 6.0 ~ 8.5g / dl, which is the normal range, before and after intake of herbal diet food.

이와 같은 현상은 임상실험용으로 제조된 한방다이어트식품에 함유되어 있는 가용성무질소물의 함량이 65.94%인데 비하여 단백질의 함량은 7.59%만이 함유되어 본 임상실험으로 인하여 임상대상자들의 혈액 중 단백질 함량에는 영향이 미미한 것으로 판단되었다.This phenomenon has 65.94% of the soluble nitrogen content contained in the herbal diet food prepared for clinical trials, whereas only 7.59% of the protein content is included. It was considered insignificant.

한방다이어트식품의 섭취기간별 혈액 중 단백질함량의 변화(g/㎗)Changes in Protein Content of Blood by Intake Period of Herbal Diet Foods (g / ㎗) 성명name 섭취전Before Intake 30일30 days 60일60 days 90일90 days 변화량Change F01F01 7.17.1 7.87.8 8.28.2 7.67.6 +0.5+0.5 F02F02 8.68.6 8.48.4 8.18.1 7.27.2 -0.6-0.6 F03F03 7.77.7 8.38.3 8.18.1 6.36.3 -1.4-1.4 F04F04 7.87.8 8.18.1 8.28.2 8.28.2 +0.4+0.4 F05F05 8.38.3 8.58.5 7.37.3 8.28.2 -0.1-0.1 M01M01 7.77.7 8.28.2 7.87.8 7.47.4 -0.3-0.3 F06F06 8.48.4 8.28.2 8.58.5 7.17.1 -1.3-1.3 F07F07 8.58.5 8.68.6 7.67.6 7.77.7 -0.8-0.8 F08F08 8.28.2 8.68.6 8.58.5 7.57.5 -0.7-0.7 F09F09 8.18.1 8.08.0 8.48.4 8.38.3 +0.2+0.2 F10F10 8.08.0 8.28.2 8.68.6 8.58.5 +0.5+0.5 F11F11 8.38.3 8.48.4 8.28.2 7.47.4 -0.9-0.9 F12F12 8.78.7 8.38.3 8.28.2 8.28.2 -0.5-0.5 F13F13 8.78.7 8.18.1 8.08.0 8.28.2 -0.5-0.5 M02M02 8.58.5 8.28.2 8.38.3 7.97.9 -0.6-0.6 F14F14 7.77.7 8.08.0 8.08.0 7.97.9 +0.2+0.2 F15F15 8.08.0 8.18.1 8.38.3 7.97.9 -0.1-0.1 M03M03 7.87.8 8.48.4 8.68.6 8.38.3 +0.5+0.5 F16F16 8.48.4 8.18.1 8.28.2 8.58.5 +0.1+0.1 F17F17 8.48.4 7.77.7 8.38.3 7.77.7 -0.7-0.7 F18F18 8.38.3 8.18.1 8.58.5 8.68.6 +0.3+0.3 F19F19 8.18.1 7.87.8 8.28.2 8.38.3 +0.2+0.2 F20F20 8.48.4 7.87.8 7.07.0 7.37.3 -1.1-1.1 F21F21 7.77.7 7.97.9 8.68.6 7.77.7 00 F22F22 8.18.1 7.77.7 8.18.1 7.97.9 -0.2-0.2 F23F23 7.97.9 7.77.7 8.28.2 7.37.3 -0.6-0.6 F24F24 8.78.7 7.87.8 8.18.1 8.08.0 -0.7-0.7 F25F25 8.48.4 8.48.4 7.77.7 6.96.9 -1.5-1.5 F26F26 8.68.6 8.38.3 8.38.3 7.57.5 -1.1-1.1 F27F27 8.38.3 8.08.0 8.08.0 8.58.5 +0.2+0.2 F28F28 8.48.4 8.48.4 8.28.2 8.48.4 00 F29F29 8.28.2 7.87.8 8.38.3 7.67.6 -0.6-0.6 F30F30 8.58.5 8.08.0 8.38.3 7.87.8 -0.7-0.7 F31F31 8.78.7 7.97.9 7.77.7 8.28.2 -0.5-0.5 F32F32 8.08.0 7.67.6 8.08.0 7.37.3 -0.7-0.7 F33F33 8.28.2 8.28.2 8.48.4 8.18.1 -0.1-0.1 F34F34 8.38.3 8.08.0 8.48.4 8.18.1 -0.2-0.2 F35F35 8.28.2 8.08.0 8.08.0 8.08.0 -0.2-0.2

* 정상치 : 6.0∼8.5g/㎗* Normal value: 6.0 ~ 8.5g / ㎗

13. 혈액 중 알부민함량의 변화13. Changes in Albumin Content in Blood

임상실험기간 중 혈액 중 알부민의 함량을 조사한 결과는 표 18과 같았다.Table 18 shows the albumin content in blood during the clinical trial.

한방다이어트식품의 섭취기간별 혈액 중 알부민함량의 변화(g/㎗)Changes in Albumin Content in Blood by Intake Period of Herbal Diet Foods (g / ㎗) 성명name 섭취전Before Intake 30일30 days 60일60 days 90일90 days 변화량Change F01F01 4.34.3 4.44.4 4.84.8 4.74.7 +0.4+0.4 F02F02 5.05.0 4.94.9 4.94.9 4.54.5 -0.5-0.5 F03F03 4.84.8 4.84.8 4.74.7 4.34.3 -0.5-0.5 F04F04 4.74.7 4.74.7 4.94.9 4.74.7 00 F05F05 4.84.8 4.94.9 4.64.6 4.84.8 00 M01M01 4.84.8 4.94.9 4.84.8 4.84.8 00 F06F06 4.94.9 4.64.6 4.94.9 4.54.5 -0.4-0.4 F07F07 5.05.0 4.94.9 4.54.5 4.54.5 -0.5-0.5 F08F08 4.54.5 4.84.8 4.84.8 4.34.3 -0.2-0.2 F09F09 4.84.8 4.74.7 4.94.9 5.05.0 +0.2+0.2 F10F10 4.64.6 4.44.4 4.64.6 4.54.5 -0.1-0.1 F11F11 4.84.8 5.05.0 4.74.7 4.64.6 -0.2-0.2 F12F12 5.45.4 4.64.6 5.05.0 4.94.9 -0.5-0.5 F13F13 5.05.0 4.54.5 4.14.1 4.54.5 -0.5-0.5 M02M02 5.25.2 4.64.6 4.94.9 4.94.9 -0.3-0.3 F14F14 4.14.1 4.54.5 4.24.2 4.04.0 -0.1-0.1 F15F15 4.84.8 4.64.6 4.84.8 4.84.8 00 M03M03 4.64.6 4.74.7 4.84.8 4.74.7 +0.1+0.1 F16F16 4.64.6 4.34.3 4.34.3 4.94.9 +0.3+0.3 F17F17 4.84.8 4.34.3 4.84.8 4.74.7 -0.1-0.1 F18F18 4.74.7 4.44.4 4.94.9 4.84.8 +0.1+0.1 F19F19 4.84.8 4.44.4 5.05.0 4.84.8 00 F20F20 4.94.9 4.64.6 4.34.3 4.54.5 -0.4-0.4 F21F21 4.54.5 4.44.4 4.84.8 4.54.5 00 F22F22 4.54.5 4.34.3 4.94.9 4.74.7 +0.2+0.2 F23F23 4.64.6 4.24.2 4.84.8 4.54.5 -0.1-0.1 F24F24 4.94.9 4.34.3 4.84.8 4.54.5 -0.4-0.4 F25F25 4.54.5 5.05.0 4.84.8 4.54.5 00 F26F26 5.15.1 4.64.6 4.94.9 5.05.0 -0.1-0.1 F27F27 5.05.0 4.54.5 4.84.8 4.84.8 -0.2-0.2 F28F28 4.64.6 4.44.4 4.74.7 4.64.6 00 F29F29 4.84.8 4.44.4 4.74.7 4.64.6 -0.2-0.2 F30F30 5.05.0 4.54.5 4.14.1 4.84.8 -0.2-0.2 F31F31 5.05.0 4.34.3 4.44.4 4.64.6 -0.4-0.4 F32F32 4.74.7 4.34.3 4.84.8 4.44.4 -0.3-0.3 F33F33 4.64.6 4.34.3 4.84.8 4.74.7 +0.1+0.1 F34F34 4.94.9 4.54.5 4.94.9 4.84.8 -0.1-0.1 F35F35 4.64.6 4.34.3 4.74.7 4.54.5 -0.1-0.1

* 정상치 : 3.5∼5.0g/㎗* Normal value: 3.5 ~ 5.0g / ㎗

상기의 표18에서 알 수 있는 바와 같이 임상대상자 38명 중 23명은 소량 감소하는 경향을 보였으며, 7명은 증가하였으며, 8명은 변화가 없었다. 표16의 혈액중 단백질의 함량변화에서와 같이 38명의 모두 한방다이어트식품의 섭취 이전과 이후에 모두 정상치의 범위인 3.5∼5.0g/㎗에 속하여 본 임상실험에서는 혈액 중 알부민의 함량에 영향이 매우 적은 것으로 나타났다.As can be seen from Table 18, 23 out of 38 clinical subjects showed a small decrease, 7 increased, and 8 did not change. As shown in Table 16, the protein content in the blood belongs to the normal range of 3.5-5.0 g / ㎗ before and after intake of herbal diet foods. Less.

14. 혈액 중 요산함량의 변화14. Changes in uric acid content in the blood

임상기간에 따른 임상대상자들의 혈액 중 요산의 함량에 대한 변화를 조사한 결과는 표19와 같았다.Table 19 shows the changes in the uric acid content in the blood of the clinical subjects according to the clinical period.

표19의 결과에서와 같이 임상실험기간 중 혈액 중 요산의 함량을 1개월 단위로 조사한 결과 전체 임상대상자 38명에서 21명은 조금 감소하였고, 14명은 증가하였지만 3명은 함량의 변화가 없었다. 전체 38명의 임상대상자들의 대부분은 정상치인 3.0∼7.0㎎/㎗의 범위에 속하였으나, 1명은 정상치 보다 그 함량이 높았고, 1명은 정상치 보다 낮았다. 이와 같은 현상은 모두 임상실험 전에 정상치의 범위에서 높았거나 낮았기 때문으로 한방다이어트식품의 섭취로 영향은 아닌 것으로 확인되었다.As shown in the results of Table 19, the uric acid content in the blood during the clinical trials was measured on a monthly basis. In 38 patients, 21 were slightly decreased, 14 were increased, but 3 were unchanged. Most of the 38 clinical subjects were in the range of 3.0 ~ 7.0mg / dl, which is normal, but one was higher than normal and one was lower than normal. All of these phenomena were high or low in the normal range before the clinical trial, so it was confirmed that they were not affected by the intake of herbal diet foods.

한방다이어트식품의 섭취기간별 혈액 중 요산함량의 변화(㎎/㎗)Changes in Uric Acid Content in Blood by Intake Period of Herbal Diet Foods (mg / ㎗) 성명name 섭취전Before Intake 30일30 days 60일60 days 90일90 days 변화량Change F01F01 2.72.7 2.12.1 4.44.4 3.63.6 +0.9+0.9 F02F02 4.04.0 5.05.0 6.26.2 3.23.2 -0.8-0.8 F03F03 8.58.5 7.37.3 8.68.6 5.05.0 -3.5-3.5 F04F04 3.83.8 3.33.3 4.14.1 4.04.0 +0.2+0.2 F05F05 5.35.3 4.64.6 3.03.0 4.54.5 -0.8-0.8 M01M01 8.58.5 8.18.1 6.96.9 6.56.5 -2.0-2.0 F06F06 7.07.0 6.06.0 7.37.3 7.07.0 00 F07F07 3.83.8 4.04.0 2.82.8 4.04.0 +0.2+0.2 F08F08 5.65.6 5.25.2 4.44.4 3.53.5 -2.1-2.1 F09F09 7.27.2 6.26.2 6.36.3 6.46.4 -0.8-0.8 F10F10 6.56.5 6.16.1 6.66.6 6.56.5 00 F11F11 4.64.6 3.93.9 4.94.9 5.15.1 +0.5+0.5 F12F12 4.74.7 3.43.4 4.94.9 4.74.7 00 F13F13 5.35.3 3.33.3 3.03.0 4.04.0 -1.3-1.3 M02M02 9.09.0 5.95.9 5.75.7 7.17.1 -1.9-1.9 F14F14 4.54.5 6.16.1 5.85.8 5.25.2 +0.7+0.7 F15F15 4.34.3 4.14.1 5.25.2 4.04.0 -0.3-0.3 M03M03 7.27.2 7.17.1 7.07.0 5.45.4 -1.8-1.8 F16F16 5.75.7 4.24.2 4.14.1 3.23.2 -2.5-2.5 F17F17 3.93.9 2.62.6 3.83.8 5.05.0 +1.1+1.1 F18F18 2.02.0 2.52.5 2.42.4 2.42.4 +0.4+0.4 F19F19 5.15.1 4.04.0 5.35.3 3.93.9 -1.2-1.2 F20F20 5.95.9 6.26.2 9.79.7 5.35.3 -0.6-0.6 F21F21 4.14.1 3.73.7 4.84.8 5.25.2 +1.1+1.1 F22F22 5.05.0 5.15.1 4.54.5 4.64.6 -0.4-0.4 F23F23 4.24.2 4.14.1 4.54.5 3.93.9 -0.3-0.3 F24F24 4.74.7 3.93.9 4.14.1 4.04.0 -0.7-0.7 F25F25 6.06.0 6.46.4 7.37.3 3.73.7 -2.3-2.3 F26F26 2.02.0 1.71.7 2.62.6 3.13.1 +1.1+1.1 F27F27 5.85.8 4.34.3 5.25.2 6.96.9 +1.1+1.1 F28F28 5.15.1 3.73.7 4.84.8 4.94.9 -0.2-0.2 F29F29 3.53.5 2.52.5 4.94.9 4.94.9 +1.4+1.4 F30F30 5.25.2 4.14.1 5.05.0 4.34.3 -0.9-0.9 F31F31 5.35.3 4.04.0 3.83.8 5.55.5 +0.2+0.2 F32F32 3.83.8 3.33.3 4.24.2 4.94.9 +1.1+1.1 F33F33 5.25.2 3.13.1 4.54.5 4.54.5 -0.7-0.7 F34F34 5.45.4 4.64.6 6.16.1 6.26.2 +0.8+0.8 F35F35 6.66.6 5.25.2 7.07.0 6.56.5 -0.1-0.1

* 정상치 : 3.0∼7.0㎎/㎗* Normal value: 3.0∼7.0㎎ / ㎗

상기에서 알 수 있는 바와 같이, 본 발명의 다시마 및 한방 생약재를 이용한체중조절용 특수영양식품의 제조방법은 체지방율, 혈청 중성지질 및 총콜레스테롤 함량의 감소를 위한 비만자의 건강증진에 효과가 있는 것으로 다시마, 한방 생약재, HCA 및 무기질이 혼합되어 그 효능을 더욱 증진시킬 수 있도록 한 것이다.As can be seen from the above, the method of manufacturing a special nutrition for weight control using tangles and herbal herbal medicines of the present invention is effective in the health promotion of obese for the reduction of body fat percentage, serum triglycerides and total cholesterol content. Herbal herbal medicine, HCA and minerals will be mixed to further enhance the efficacy.

Claims (2)

다시마, 율무, 알로애, 흑두, 당귀, 솔잎, 갈근, 으름, 저령, 맥아를 포함하는 주원료와, 차전차피, 백복령 및 가르시니아 캄보지아를 포함하는 부원료인 한방 생약재를 분말상태로 하고;Powdered Chinese herbal medicines including main raw materials including kelp, yulmu, aloe, black bean, donkey, pine needles, black root, squirt, spirit, malt and by-products including chachapi, baekbokryeong and garcinia cambogia; 두충, 가시오가피, 매실, 오미자 및 죽엽을 포함하는 주원료와 생녹용과 맥문동을 포함하는 부원료에 5배의 물을 가하여 90∼130℃의 온도에서 1∼4시간 동안 고압 가열, 추출하며;5 times of water was added to the main raw materials including tofu, barley, plum, Schisandra chinensis and bamboo leaf, and the subsidiary raw materials including fresh antler and pulmonary dong to heat and extract for 1 to 4 hours at a temperature of 90 to 130 ° C; 상기 추출액에 홍삼농축액 0.1중량%를 첨가하여 액상의 추출액을 제조하고;Adding 0.1% by weight of red ginseng concentrate to the extract to prepare a liquid extract; 소정의 비율로 배합된 상기 분말 한방 생약재와 수용성 키토올리고당, 비타민류 및 무기성분류등을 소량 첨가하여 상기 추출액과 혼합하여 반죽하고;Adding a small amount of the powdered herbal herbal medicines, water-soluble chitooligosaccharides, vitamins, and inorganic components, blended in a predetermined ratio, and kneading the mixture with the extract; 상기 반죽물을 환으로 형성하여 타정 및 열풍 건조시킴을 특징으로 하는 체중 조절용 특수영양식품의 제조 방법.Forming the dough into a ring, the tableting and hot air drying method for producing a special nutritional product characterized in that the drying. 제1항에 있어서, 상기 분말상 한방 생약재 및 액상추출물은 다음과 같은 배합비율을 가짐을 특징으로 하는 체중 조절용 특수영양식품의 제조 방법.According to claim 1, wherein the herbal herbal medicine powder and liquid extract is a method for producing a special nutrition for weight control, characterized in that it has a blending ratio as follows. 다시마15중량%, 율무10중량%, 알로애6중량%, 흑두5중량%, 당귀5중량%, 솔잎5중량%, 갈근5중량%, 으름3중량%, 저령3중량%, 맥아3중량%, 차전자피12중량%, 백복령5중량%, 가르시니아, 수용성 키토올리고당, 비타민류 및 무기성분(Fe, Ca, Zn)1중량%, 홍삼농축액0.1중량%, 두충6중량%, 가시오가피3중량%, 매실3중량%, 오미자3중량%, 죽엽2.9중량%, 생녹용2중량%, 맥문동2중량%.15% by weight of kelp, 10% by weight of radish, 6% by weight, 6% by weight of black bean, 5% by weight of Angelica, 5% by weight of pine needles, 5% by weight of brown root, 3% by weight of erosion, 3% by weight of malt, 3% of malt, Tea weight 12%, Baekbokyeong 5%, Garcinia, water-soluble chitooligosaccharides, vitamins and inorganic components (Fe, Ca, Zn) 1% by weight, red ginseng concentrate 0.1% by weight, tofu 6% by weight, 3% by weight of oogapi, plum 3 Wt.%, Schisandra chinensis 3%, Bamboo leaf 2.9%, Fresh antler 2%, Macmundong 2%.
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