KR20010091416A - A marking method of health-help food, medical composite and special-nutritious food for improve the corpulence and the food - Google Patents

Abstract

PURPOSE: A method for producing health food supplements, pharmaceuticals and special nutritional foods for improving obesity is provided, to improve obesity constitution by decreasing the blood fat and body fat of a human without skipping meals or harmful effects. CONSTITUTION: The method for producing health food supplements, pharmaceuticals and special nutritional foods comprises the steps of: mixing the washed medicinal herbs; drying the mixed medicinal herbs; inserting the dried medicinal herbs into an extracting tank and adding 30% alcohol into the tank and extracting them; storing the extract for a certain period of time to precipitate solid materials; centrifuging the extract to obtain the supernatant; concentrating the supernatant under reduced pressure; spray-drying the concentrate to produce the dried powder having 8% or less humidity; collecting the dried powder having similar size; and drying the dried powder to 5 or less of humidity.

Description

A marking method of health-help food, medical composite and special-nutritious food for improve the corpulence and the food}

The present invention relates to a method for manufacturing health supplements, pharmaceutical compositions, and special nutritional products for improving obesity, and more particularly, to reducing obesity by reducing blood fat and body fat without starving food or harming the human body. The present invention relates to a method for preparing health supplements, pharmaceutical compositions, and special nutritional products for improving obesity that can prevent adult diseases caused by obesity by improving body line and foods thereof.

In general, as the economy develops, the income level rises, the westernization of diet is rapidly increasing, and the adult disease caused by obesity is rapidly increasing. Recently, many diet foods have been developed and sold to prevent and overcome such obesity.

However, the conventional diet foods and diet starving methods such as the rapid cut off of the supply of various nutrients necessary for the human body is not only difficult to maintain a balanced nutritional state, but also causes fatal nutritional deficiency, etc. There was a problem of harm to health.

The present invention has been made in view of the conventional problems as described above, the purpose is to reduce the fat and body fat in the blood without starving or harming the human body to improve the obesity gland can prevent adult diseases caused by obesity The present invention provides a method for preparing health supplements, pharmaceutical compositions and special nutritional products for improving obesity, and foods thereof.

The object of the present invention comprises the steps of mixing a predetermined ratio of a plurality of herbal medicines washed with purified water and foreign substances removed; Drying the mixed raw materials under a predetermined temperature for a predetermined time; Adding the dried raw material to an extraction tank, adding a predetermined amount of 30% alcohol, and then stirring the mixture for a predetermined time at a predetermined temperature to extract the extract; Precipitating the extract at a predetermined temperature for a predetermined time to precipitate the polymer material contained in the extract; Centrifuging the supernatant by centrifuging the extract from which the polymer material has been removed; A concentrated step of concentrating the centrifuged supernatant under a reduced pressure concentrator for a predetermined time to obtain a concentrated liquid having a solid content of 30%; A spray drying step of spray drying the concentrate with a spray dryer to obtain a dry powder having a moisture content of 5% or less; It can be achieved by the method of manufacturing the health supplement food, pharmaceutical composition and special nutrition for improving obesity, characterized in that it comprises the step of forming the tablet into a predetermined size by an automatic tableting machine.

1 is a block diagram illustrating a manufacturing process of the manufacturing method of the health supplement food, pharmaceutical composition and special nutrition for improving obesity according to the present invention.

♣ Explanation of symbols for main part of drawing ♣

100: mixing step 110: raw material drying step

120: extract extraction step 130: precipitation step

140: centrifugation step 150: decompression concentration step

160: spray drying step 170: tablet molding step

Hereinafter, with reference to the accompanying drawings it will be described a method for producing a health supplement food, a pharmaceutical composition and a special nutrition for improving obesity according to a preferred embodiment of the present invention and the food.

1 is a block diagram illustrating a manufacturing process of the manufacturing method of health supplement food, pharmaceutical composition and special nutrition for improving obesity according to the present invention.

Referring to Figure 1, the manufacturing method of the health supplement food, medicinal composition and special nutrition for improving obesity according to the present invention is a herbal medicine raw material mixing step (100), raw material drying step (110), extract extraction step (120) ), A precipitation step 130, a centrifugation step 140, a reduced pressure concentration step 150, a spray drying step 160, and a tablet molding step (170).

The medicinal herb raw material mixing step 100 is to mix a plurality of medicinal herb raw materials washed with purified water and foreign substances removed in a predetermined ratio, the medicinal herb raw materials and their mixing ratio may be mixed, but preferably the following six It is good to carry out by mixing method. In other words, 1) Huang Lotus 9.87%, Raw Sulfur 9.87%, Chunhwa 9.87%, Angelica 9.87%, Schisandra chinensis 9.87%, Baekbokyeong 9.87%, Macmun-dong 9.87%, Licorice 9.87%, Ginseng 9.87%, Dried dry greens 1.87% and Bamboo leaf 1.30% ; 2) mix 5.87% rhubarb, 10.37% raw sulfur, 10.37%, natural part 10.37%, Angelica 10.37%, Schisandra chinensis 10.37%, Baekbokryeong 10.37%, Macmundong 10.37%, licorice 10.37%, ginseng 10.37%, dried brown 10.37%, and bamboo leaf 0.80%; 3) mix 10.50% rhubarb, 9.80% raw barley, 9.80% cheonhwa, 9.80%, Schisandra chinensis 9.80%, Baekbokyeong 9.80%, Macmun-dong 9.80%, licorice 9.80%, ginseng 9.80%, dried dry brown 80% and 1.30%; 4) mix ginseng 20.00%, fresh turmeric 10.00%, cheonhwa flour 10.00%, Angelica 10.00%, Schisandra chinensis 10.00%, Baekbokyeong 10.00%, Macmundong 10.00%, licorice 10.00%, dried dried fish 10.00% and gardenia 0.10%; 5) mix ginseng 11.10%, fresh green sulfur 11.10%, cheonhwa flour 11.10%, Angelica 11.10%, Schisandra chinensis 11.10%, Baekbokryeong 11.10%, Macmundong 11.10%, licorice 11.10%, dried brownfish 11.10% and gardenia 0.10%; 6) mix ginseng 11.90%, fresh green sulfur 11.00%, cheonhwa flour 11.00%, Angelica 11.00%, Schisandra chinensis 11.00%, Baekbokyeong 11.00%, Macmun-dong 11.00%, licorice 11.00%, dried dried 11.00% and gardenia 0.10%; 7) Cha bark 12.00%, rhubarb 9.00%, Saenghwanghwang 8.17%, Cheonhwa flour 8.17%, Angelica 8.16%, Schisandra chinensis 9.00%, Baekbokyeong 9.00%, Macmundong 9.00%, Licorice 9.00%, Ginseng 8.50%, Dried dry green 8.50%, and bamboo leaf 1.50% To mix; 8) Charcoal Blood 17.00%, Rhubarb 8.00%, Saengjihwang 8.17%, Chunhwa 8.16%, Angelica 8.17%, Schisandra 8.00%, Baekbokyeong 7.00%, Macmun-dong 9.00%, Licorice 8.00%, Ginseng 9.00%, Dried 8.00% and Bamboo Leaf 1.50% To mix; 9) Cha Cha Blood 20.00%, Rhubarb 8.00%, Saenghwanghwang 7.17%, Chunhwa 7.16%, Angelica 7.17%, Schisandra 8.00%, Baekbokyeong 7.00%, Macmundong 8.00%, Licorice 8.00%, Ginseng 9.00%, Dried dry 7.00% and Bamboo leaf 1.50% To mix; 10) mix chaff 25.00%, raw green grass 8.17%, cheonhwa flour 8.17%, Angelica 8.16%, Schisandra chinensis 8.00%, Baekbokyeong 8.00%, Macmun-dong 8.00%, licorice 8.00%, ginseng 8.50%, dried dry green 50%, and bamboo shoot 1.50%; 11) Cha Cha blood 30.00%, raw green sulfur 8.17%, Cheonhwa flour 5.16%, Angelica 8.17%, Schisandra chinensis 8.00%, Baekbokyeong 7.00%, Macmundong 9.00%, Licorice 7.50%, Ginseng 8.00%, dried dry green 50% and 1.50%; 12) Cha Cha blood 28.00%, raw green sulfur 8.17%, Cheonhwa flour 6.16%, Angelica 8.17%, Schisandra chinensis 8.50%, Baekbokyeong 7.50%, Macmun-dong 9.00%, Licorice 7.50%, Ginseng 8.00%, dried dry greens 7.50% and bamboo shoots 1.50%; 13) Hwanghyun extract powder 9.00%, Ginseng extract powder 9.00%, Schisandra chinensis extract powder 8.00%, Baekbokryeong extract powder 8.00%, Raw liquor extract powder 8.00%, Magmundong extract powder 8.00%, Angelica extract powder 8.00%, Brown root extract powder 8.00%, Licorice extract Extract Powder 8.00%, Chunhwa Extract Powder 8.00%, Licorice Extract Powder 8.00%, Confectionery Extract Powder 6.00%, Herbal Extract Powder 3.00%, Astragalus Extract Powder 3.00%, Chaga Extract Powder 2.00%, Cucumber Extract Powder 2.00%, Bamboo Leaf Extract Mix 2.00% of powder; 14) Cha Cha Blood 12.00%, Macmundong Extract Powder 12.58%, Raw Sulfur Extract Powder 10.19%, Angelica Extract Extract Powder 10.19%, Schisandra chinensis Extract Powder 9.29%, Baekbokyeong Extract Powder 9.29%, Brown Root Extract Powder 9.29%, Licorice Extract Powder 9.29%, Copper Powder 3.61%, sewage extract powder 2.71%, samsam extract powder 2.71%, bamboo leaf extract powder 2.71%, anti-terminal extract powder 2.71%, deficiency extract powder 2.70%, powder of dew extract powder 0.72%, tooth extract 0.01%.

When the mixing step 100 as described above is completed, the raw material drying step 110 is carried out.

The raw material drying step 110 is to dry the herbal medicine ingredients mixed in the mixing step 100 for a predetermined time under a predetermined temperature, the temperature is 18 ℃ to 21 ℃, the drying time is preferably carried out to 2 to 4 hours. .

When the medicinal herb ingredients mixed by the raw material drying step 110 are dried, the extract extraction step 120 is performed.

The extract extraction step 120 is to put the dried raw material into the extraction tank, add a predetermined amount of 30% alcohol and then stirred for a predetermined time under a predetermined temperature to extract the extract, the amount of 30% alcohol added It is preferable to carry out 4 to 6 times the amount of the herbal medicine input to the extraction tank, the temperature is 25 to 27 ℃, the time is 6 to 8 hours.

When the extract is extracted from the herbal medicine mixture through the extract extraction step 120, the precipitation step 130 is carried out.

The precipitation step 130 is to remove the polymer material by precipitating the polymer material contained in the extract by leaving the extract extracted through the extract extraction step 120 for a predetermined time under a predetermined temperature, 8 to 10 ℃ Preference is given to performing for 20 to 26 hours under temperature.

The extract, in which the polymer material is removed by the precipitation step 130, removes the smaller polymer material contained in the extract through the centrifugation step 140.

The centrifugation step 140 is to remove the smaller polymer material contained in the extract by centrifuging the supernatant by centrifuging the extract, in which the first large polymer material is removed through the precipitation step 130, and the first step. It consists of a centrifugation step 140a and a one-dimensional deep separation step 104b.

The first centrifugation step (140a) is obtained by centrifuging the extract liquid from the polymer material removed through the precipitation step 130 for 20 minutes at a rotational speed of 1500rpm by a centrifuge to obtain a supernatant, the first centrifugation step ( 140b) is obtained by allowing the supernatant obtained in the first centrifugation step 140a to stand for 24 hours at a temperature of 4 to 6 ° C. and then centrifuging for 15 minutes at a rotational speed of 2000 rpm using a centrifuge.

When the centrifugation step 140 is completed as described above, the decompression concentration step 150 is performed.

The reduced pressure concentration step 150 is to obtain a concentrated liquid of 30% solids by concentrating the centrifuged supernatant under a predetermined temperature under a reduced pressure concentrator for a predetermined time, preferably carried out at a temperature of 58 ℃ to 60 ℃.

When the concentrated liquid of 30% solids is obtained through the reduced pressure concentration step 150, the spray drying step 160 is performed.

The spray drying step 160 is to obtain a dry powder of less than 5% moisture by spray drying the concentrate of the solid content 30% by spray dryer, the inlet temperature of the spray dryer to maintain 150 ℃, the outlet temperature It is preferable to carry out on condition of keeping 80 degreeC.

When a dry powder having a moisture of 5% or less is obtained through the spray drying step 160, the tablet molding step 170 is performed.

The tablet molding step 170 may be completed as a health supplement food for improving obesity according to the present invention by molding the dry powder of the moisture 5% or less by a predetermined size by an automatic tableting machine to form a pill of a predetermined size. It is.

The health supplement food, pharmaceutical composition and special nutrition for the improvement of obesity according to the present invention prepared by the manufacturing method as described above was tested by the following method, the experimental results are as follows.

In the test subjects, Sprague Dawley rats (white rats) weighing about 220 g were supplied with sufficient water and solid feed (Samyang Oil Feed Co., Ltd.) for 2 weeks or longer, and then used in the experiment. Twelve patients were weighed and serum lipids were measured.

Body weight was measured by an anthropo meter (Model AHW-2A, Shimadzu, Tyokyo, Japan), and the body weight was reconfirmed by using a casing weight (Model 150A, Kas, Korea).

In the experimental method, the weight fluctuation experiment of the white paper was conducted in the same manner as the experimental method such as milk, the experiment for humans was to take the product according to the invention three times a day made of tablets, and the weight and Serum lipid concentrations were measured. Abdominal fat was measured before and after 12 weeks with BMD (Hologic QDR 2000, Hologic Inc., Waltham. Massachusetts, U.S.A.).

As for the weight change among the experimental results of the subjects, the weight loss was recognized from 6 weeks after the administration in the white paper. The body mass index of the participants in the experiment was 27.18 ± 0.54% on average. At 3 months, 26.30 ± 0.69% was significantly decreased (p <0.0005), and the average body weight was 77.48 ± 3.5 kg in humans.

The serum triglyceride concentration was 409.0 ± 60.80 ㎎ / ㎗ before administration in 4 persons whose serum triglycerides exceeded the normal range and 200.25 ± 31.00 ㎎ / ㎗ at 4 weeks after administration. p <0.025) was observed. In 8 patients with total cholesterol greater than 200 mg / dL, there was a significant decrease (p <0.001) from 223.5 + 6.19 mg / dL to 189.38 + 6.60 mg / dL before administration and serum HDL concentration was 47.63. There was no significant change from +3.64 mg / dL to 45.88 + 3.40.

In terms of body fat change, abdominal body fat decreased from 42.54 + 2.12% before treatment to 36.41 + 2.59% after treatment, 6.13 + 1.51% (p <0.005), and total body fat except for tofu decreased from 40.39 + 2.53% to 35.49 + 2.65%. 4.9 + 1.23% significantly decreased (p <0.005).

According to the present invention described above, it is possible to prevent the adult disease caused by obesity by improving the obesity gland by reducing blood fat and body fat without starving food or harming the human body.

Claims (22)

Mixing a plurality of herbal medicine raw materials washed with purified water and foreign substances removed at a predetermined ratio (100); Drying the mixed raw materials for a predetermined time under a predetermined temperature (110); Injecting the dried raw material into an extraction tank, adding a predetermined amount of 30% alcohol and stirring the mixture for a predetermined time at a predetermined temperature (120); A step (130) of precipitating the extract liquid under a predetermined temperature for a predetermined time to precipitate the polymer material contained in the extract; A centrifugation step (140) for taking the supernatant by centrifuging the extract from which the polymer material has been removed; A concentrated concentration step 150 for concentrating the centrifuged supernatant under a predetermined temperature under a reduced pressure concentrator to obtain a concentrated liquid having a solid content of 30%; Spray drying step of spray drying the concentrated solution to obtain a dry powder of less than 8% moisture by spray drying; Tableting the dry powder to a predetermined size by an automatic tableting machine (170); Method of producing a dietary supplement, pharmaceutical composition and special nutrition for improving obesity, characterized in that the step of drying the tableting molding to 180% or less moisture. According to claim 1, wherein the herbal ingredients of the mixing step 100 is raw sulfur rye 9.87%, raw sulfur sulfur 9.87%, cheonhwa flour 9.87%, Angelica 9.87%, Schisandra chinensis 9.87%, Baekbokyeong 9.87%, Macmundong 9.87%, licorice 9.87%, ginseng 9.87 Method for producing health supplements, medicinal compositions and special nutrition for the improvement of obesity, characterized in that%, dried dry grass 9.87% and bamboo leaf 1.30%. According to claim 1, wherein the raw material of the medicinal herbs of the mixing step (100) is 5.87%, raw green sulfur 10.37%, cheonhwa 10.37%, Angelica 10.37%, Schisandra chinensis 10.37%, Baekbokyeong 10.37%, Mcmundong 10.37%, licorice 10.37%, ginseng 10.37 A method for producing health supplements, pharmaceutical compositions and special nutritional products for the improvement of obesity, characterized in that%, dried 10.37% and bamboo leaf 0.80%. According to claim 1, The raw material of the herbal medicine of the mixing step 100 is sulfuric acid 10.50%, raw sulfur sulfur 9.80%, cheonhwa flour 9.80%, Angelica 9.80%, Schisandra chinensis 9.80%, Baekbokyeong 9.80%, Mcmundong 9.80%, licorice 9.80%, ginseng 9.80 Method for producing health supplements, pharmaceutical compositions and special nutritional products for the improvement of obesity, characterized in that the percentage, 9.80% dried dried and 1.30%. According to claim 1, wherein the herbal ingredients of the mixing step 100 is ginseng 20.00%, raw green sulfur 10.00%, cheonhwa flour 10.00%, Angelica 10.00%, Schisandra chinensis 10.00%, Baekbokyeong 10.00%, Macmundong 10.00%, licorice 10.00%, dried brown 10.00 % And Gardenia 0.10%, the method for producing health supplements, pharmaceutical compositions and special nutrition for the improvement of obesity. According to claim 1, wherein the herbal ingredients of the mixing step 100 is ginseng 11.10%, raw green sulfur 11.10%, cheonhwa flour 11.10%, Angelica 11.10%, Schisandra chinensis 11.10%, Baekbokyeong 11.10%, Mcmundong 11.10%, licorice 11.10%, dry brown 11.10 % And Gardenia 0.10%, the method for producing health supplements, pharmaceutical compositions and special nutrition for the improvement of obesity. According to claim 1, The raw material of the herbal medicine of the mixing step 100 ginseng 11.90%, fresh green sulfur 11.00%, cheonhwa flour 11.00%, Angelica 11.00%, Schisandra chinensis 11.00%, Baekbokyeong 11.00%, Macmundong 11.00%, licorice 11.00%, dried brown 11.00 % And Gardenia 0.10%, the method for producing health supplements, pharmaceutical compositions and special nutrition for the improvement of obesity. According to claim 1, wherein the herbal medicine raw material of the mixing step 100 is 12.00% tea bark, sulfur 9.00%, raw green sulfur 8.17%, cheonhwa flour 8.17%, Angelica 8.16%, Schisandra chinensis 9.00%, Baekbokyeong 9.00%, Macmundong 9.00%, licorice 9.00 %, Ginseng 8.50%, dried dried 8.50% and bamboo shoots 1.50% of the health supplements, pharmaceutical compositions and special nutrition for the improvement of obesity. According to claim 1, wherein the medicinal herbs in the mixing step 100 is cha bar blood 17.00%, rhubarb 8.00%, raw green sulfur 8.17%, Cheonhwa flour 8.16%, Angelica 8.17%, Schizandra 8.00%, Baekbokyeong 7.00%, Macmundong 9.00%, Licorice 8.00 %, Ginseng 9.00%, dried 8.00% and bamboo leaf 1.50% of the dietary supplement, pharmaceutical composition and special nutrition for the improvement of obesity. According to claim 1, wherein the medicinal herbs in the mixing step 100 is tea 20.00%, rhubarb 8.00%, raw green sulfur 7.17%, cheonhwa flour 7.16%, Angelica 7.17%, Schisandra 8.00%, Baekbokyeong 7.00%, Mcmundong 8.00%, licorice 8.00 %, Ginseng 9.00%, dried dried 7.00% and bamboo leaf 1.50% of the health supplements, pharmaceutical composition and special nutrition for the improvement of obesity. According to claim 1, wherein the medicinal herbs in the mixing step 100 is 25.00% tea, raw green sulfur 8.17%, cheonhwa flour 8.17%, Angelica 8.16%, Schisandra chinensis 8.00%, Baekbokyeong 8.00%, Macmundong 8.00%, licorice 8.00%, ginseng 8.50 Method for producing health supplements, pharmaceutical compositions and special nutritional products for the improvement of obesity, characterized in that the%, dried 8.50% and bamboo leaf 1.50%. According to claim 1, wherein the medicinal herbs in the mixing step 100 is tea 30.00%, raw green sulfur 8.17%, cheonhwa flour 5.16%, Angelica 8.17%, Schisandra 8.00%, Baekbokyeong 7.00%, Mcmundong 9.00%, licorice 7.50%, Ginseng 8.00 Method for producing health supplements, pharmaceutical compositions and special nutrition for the improvement of obesity, characterized in that the%, dried dried 7.50% and bamboo leaf 1.50%. According to claim 1, wherein the herbal medicine raw material of the mixing step 100 is 28.00% of cha jeonpi, 8.17% of raw green sulfur, 8.16% of cheonhwa, 8.17%, Schisandra chinensis 8.50%, Baekbokyeong 7.50%, Macmundong 9.00%, licorice 7.50%, Ginseng 8.00 Method for producing health supplements, pharmaceutical compositions and special nutrition for the improvement of obesity, characterized in that the%, dried dried 7.50% and bamboo leaf 1.50%. According to claim 1, wherein the herbal ingredients of the mixing step 100 is Hwanghyeon extract powder 9.00%, ginseng extract powder 9.00%, Schisandra chinensis extract powder 8.00%, Baekbokryeong extract powder 8.00%, raw sulfur extract extract powder 8.00%, Macmundong extract powder 8.00 , Angelica Extract Powder 8.00%, Root Extract Powder 8.00%, Licorice Extract Powder 8.00%, Chunhua Extract Powder 8.00%, Licorice Extract Powder 8.00%, Confectionery Extract Powder 6.00%, Herbal Extract Powder 3.00%, Astragalus Extract Powder 3.00%, Method for producing health supplements, pharmaceutical compositions and special nutrition for the improvement of obesity, characterized in that the tea extract blood powder 2.00%, cowl extract powder 2.00%, bamboo leaf extract powder 2.00%. According to claim 1, wherein the medicinal herb raw material of the mixing step 100 is 12.00% cha Cha blood, 12.58% ganmun dong extract powder, 10.19% raw bran extract powder, 10.19% sugar extract extract powder 9.29%, Schisandra chinensis extract powder, 9.29%, Root extract powder 9.29%, Licorice extract powder 9.29%, Dongjak extract powder 3.61%, Sewage extract powder 2.71%, Sasam extract powder 2.71%, Bamboo leaf extract powder 2.71%, Anti-terminal extract powder 2.71%, Cultivated extract powder 2.70% The method of manufacturing health supplements, pharmaceutical compositions and special nutritional products for the improvement of obesity, characterized in that the powder 0.72%, tooth extract 0.01%. The method of claim 1, wherein the raw material drying step 110 is prepared for health supplements, medicinal compositions and special nutrition for the improvement of obesity, characterized in that carried out in the shade for 2 to 4 hours at a temperature of 18 to 21 ℃ Way. According to claim 1, wherein the extract extraction step 120, the amount of 30% alcohol added to the extraction tank together with the herbal medicine material is 4 to 6 times the amount of the raw material, 6 to 8 hours at a temperature of 25 to 27 ℃ Method for producing a dietary supplement, pharmaceutical composition and special nutrition for improving obesity, characterized in that carried out by stirring. The method of claim 1, wherein the precipitation step (130) is carried out for 20 to 26 hours at a temperature of 8 to 10 ℃, the method for producing health supplements, pharmaceutical compositions and special nutrition for improving obesity. According to claim 1, wherein the centrifugation step 140 is the first centrifugation step (140a) to obtain a supernatant by centrifuging the extract liquid polymer material is removed through the precipitation step 130 for 20 minutes at a speed of 1500rpm Wow; After the supernatant obtained in the first centrifugation step (140a) for 24 hours at a temperature of 4 to 6 ℃ and centrifuged for 15 minutes at a rotational speed of 2000rpm consisting of a second centrifugation step (140b) to obtain a supernatant A method of manufacturing health supplements, pharmaceutical compositions and special nutritional products for improving obesity. The method of claim 1, wherein the reduced pressure concentration step (150) is carried out at a temperature of 58 ° C to 60 ° C. The method of claim 1, wherein the spray drying step 16 is to improve the obesity, characterized in that carried out under the condition that the inlet temperature is maintained at 140 ℃ to 160 ℃, the outlet temperature is maintained at 70 ℃ to 90 ℃ Method for the preparation of dietary supplements, pharmaceutical compositions and special nutritional supplements. Health supplements, pharmaceutical compositions and special nutrition for the improvement of obesity, characterized in that the manufacturing method of claim 1.