KR20020076834A - Hair-restorer and it's making method - Google Patents

Abstract

PURPOSE: A hair growth promoting agent made by mixing Acanthopanacis Cortex Radicis extracts, Panax ginseng extracts, apple juice, purified glucose, citric acid, olive juice and purified water and fermenting is provided which enhances the cellular activity and dose not break the stability of skin. CONSTITUTION: This hair growth promoting agent comprises an Acanthopanacis Cortex Radicis extract and a Panax ginseng extract as a main ingredient, a mixture of apple juice, purified glucose, citric acid, olive juice and purified water in a weight ratio of 3 to 8:0.5 to 5:30 to 50:5 to 15, wherein the Acanthopanacis Cortex Radicis extract or Panax ginseng extract is prepared by extracting in water in a weight ratio of 1: 10 to 12 respectively for 2 to 3.5hr.

Description

Hair growth promoter and its manufacturing method {Hair-restorer and it's making method}

The present invention relates to a hair growth promoting agent based on the organza, ginseng and apple juice, in particular, the fermented product and the agap and ginseng fermented for a predetermined time at normal room temperature by mixing apple juice and refined glucose, etc., respectively, and low heat Ogapi liquid and ginseng solution was heated by mixing with a separate purified water.

Although genetic factors are typical, alopecia, which is caused by environmental factors, excessive stress, and pollution, has been rapidly increasing in recent twenty-thirds in the past. This alopecia is a disease that must be treated because it has a great effect on mental health, such as losing confidence in those with alopecia.

There are two methods for overcoming alopecia: using artificial hair, drinking, and applying a hair regrowth. The method of using artificial hair is cumbersome, and the method of drinking hair is generally ineffective. It is mainly used to infiltrate by applying hair repellent to the affected area.

Conventionally, the method of applying a female hormone, blood circulation accelerator, vitamin E, carotene dissolving agent, fungicide and a method of drinking minoxidil and finasteride as a hair regrowth for hair loss treatment have been used. This is being reported.

Therefore, some countries are developing hair repellents based on herbal medicines with few side effects, but they are not effective.

Considering these problems, the proposed prior art is known as 'hair growth agent and manufacturing method of ginseng-themed Korean patent application No. 1998-0047340' and 'hair loss prevention and hair growth agent' of the domestic patent application No. 2000-0058989.

Korean Patent Application No. 1998-0047340, 'Ginseng-themed hair regrowth and its manufacturing method,' is cold-pressed ginseng, Chinese herbal medicine Cheonggung, Hannyeoncho, Bogolji, Angelica, Saengyeop, safflower, red sewage, green rust with 50 ~ 70% ethanol. Alternatively, the extract is heated at 50 to 80 ° C., and the extract is centrifuged at 8,000 rpm, the supernatant is taken to dissolve the sugar extract and filtered to prepare a herbal extract, and then dl-α-tocopheral acetate, calcium pantothenate, pyridoxine-hydrochloric acid. It is a hair regrowth agent which mixes and dissolves in 50% ethanol by mixing subsidiary materials such as propylene glycol, glycerine and fruit flavor.

However, unlike conventional hair regrowth chemicals, there are no direct harms to the human body. However, as shown in the experiment, only 45% of nine people had a slight effect. Eleven (55%) of the test subjects were not responding or worsening, so there was a problem that hair growth and hair revival were not very effective.

In addition, the 'hair loss prevention and hair growth agent' of the Korean patent application No. 2000-0058989 is added to the water of Ogapi, buckwheat, and three hundred seconds, and heated to a high temperature of 120 ℃ for several hours, so that the ingredients of each material is destroyed Is significantly reduced, and this is just a tonic dose used as dandruff, constipation, hangover, etc.

The present invention is to provide an improved hair growth promoter and a method for manufacturing the same to solve the above problems.

The present invention is made by mixing the fermented mixed fermentation with a separate ratio with a separate purified water and fermented after mixing Ogapi Darin water and ginseng Darin water, and apple juice, refined glucose, citric acid, olive sugar, purified water It is to provide a hair growth promoting agent and a method of manufacturing the same.

Another object of the present invention is to use the herbal medicines such as ginseng and ginseng to eliminate side effects, and also the mixture of apple juice, refined glucose, citric acid, olive sugar, purified water is not given heat at ordinary room temperature The present invention provides a hair growth promoting agent and a method for producing the same, wherein the components and properties of each composition (material) are not lost by fermentation for a time.

Still another object of the present invention is to provide a hair growth promoting agent excellent in permeability of the medicine without side effects by using natural ingredients such as apple juice, tablet glucose, citric acid, olive sugar, including herbal medicines such as ginseng and ginseng.

The above object of the present invention,

In hair growth promoting agent, which is mainly composed of ginseng or ginseng,

Mixed fermentation broth mixed with darin liquid (Material A) by adding Ogapi to purified water, and ginseng Darin liquid (Material B) by adding ginseng to purified water, and apple juice, refined glucose, citric acid, olive sugar and purified water It is achieved by the hair growth promoter characterized by mixing (material C) and another purified water, and its manufacturing method.

The above and other objects and features of the present invention will be more clearly understood by the following detailed description.

The present invention is a method for producing a hair growth promoter using the raw materials of ginseng or ginseng,

Heating the ogapi with purified water to obtain a substance A which is a dried ogapi darin solution,

Heating ginseng with purified water to obtain substance B, which is darin ginseng darin liquid,

Deeply fermenting apple juice, refined glucose, citric acid, olive sugar, and purified water to obtain substance C, a mixed fermentation liquid,

The material A, the material B and the material C are mixed with an integer at a predetermined ratio to obtain a hair growth promoter.

First of all, the amount of Ogapi and Integer in the ratio of 1: 5 to 20, preferably 1: 8 to 15, for 2 to 3 hours 30 minutes, preferably for 2 to 30 minutes to 3 hours If used, make a substance A (organic tarin solution) by ironing on the same low light).

Ogapi, one of the main ingredients of the present invention, is a herbal medicine called the second ginseng, and is effective in helping to prevent anti-inflammatory, anti-fatigue, anti-stress, central nervous system excitement, metabolism promotion, muscle strengthening, detoxification, and blood vessel action. It is known as a medicine, anti-inflammatory action of the hair loss and help the action of blood vessels are known to play a role in strengthening the cell activity capacity.

In addition, the ratio of ginseng and purified water at a ratio of 1: 5 to 20 is preferably in a ratio of 1: 8 to 15, and for 2 hours to 3 hours 30 minutes, preferably 2 to 30 minutes to 3 hours, If used, get substance B (Ginseng Darin solution) by ironing on the same low heat as step 1.

Korean ginseng is known as an effective medicinal herb in the world under the name of Korean ginseng. In particular, by controlling the moisture balance of the dermis to prevent dehydration of the skin, it is known that the effect of delaying skin aging and preventing hair damage by having a great effect on preventing hair loss. Therefore, to increase the supply of oxygen and nutrients to the cells of the scalp will help hair growth.

Apple juice, refined glucose, citric acid, olive sugar, and purified water in a weight ratio of 15-50: 0.1-1: 0.1-1: 0.1-1: 400-550 are preferably 20-30: 0.3-0.7: 0.2-0.6: 450 After mixing at a weight ratio of ˜500, the material C (mixed fermentation liquid) is obtained by standing (deep fermentation) for 14 to 46 hours, preferably for 24 to 36 hours, at room temperature of about 30 ° C ..

In folk medicine, purified glucose, known as a substance used for malignant diseases, is known to suppress the activity of the virus. Olive sugar is rich in vitamins A, C, D, E, and F. It contains more than 40 kinds and is known to be effective in preventing aging. Olive sugar is also known to have the effect of preventing scalp aging. In addition, apple juice is known to prevent the absorption of toxic substances and to prevent abnormal fermentation in the intestine by forming a jelly-shaped wall in the intestine when ingested. You can also prevent the effect.

The weight ratio of the material A, the material B, the material C and the integer in the weight ratio of 3 to 8: 0.5 to 5: 30 to 50: 5 to 15 is preferably 4 to 6: 1 to 3: 39 to 41: 9 to 11 To obtain a hair growth promoter.

The present invention will be more clearly understood by the following examples, which are to be understood that the present invention is not limited by these examples.

Example

100 g of Ogapi and 1000 ml of water were ironed on a low heat for 2 hours and 40 minutes to obtain a substance A, which is an Ogari Darin liquid.

100 g of ginseng and 1000 ml of water were ironed on a low heat for 2 hours and 40 minutes to obtain a substance B as a ginseng darin solution.

After mixing 25 g of apple juice, 0.5 g of refined glucose, 0.4 g of citric acid, 0.4 g of olive sugar, and 473.7 g of purified water, the mixture was left at room temperature (30 ° C.) for 30 hours to obtain a mixed fermentation broth.

A hair growth promoting agent was obtained by mixing the substance A 5: substance B 2: substance C 40: constant 10 by weight.

In order to investigate the toxicity of the present invention, according to the toxicology test standard of the drug and the OECD toxicity test guideline, acute oral toxicity test and acute skin toxicity test for rats, skin irritation test and eye mucosal irritation test for rabbits, guinea pig As a result of the phototoxicity test and skin sensitization test, no death was observed, and no abnormality was observed in weight change or slaughter autopsy of all living animals.

Dose concentration (%) Animal Number A blind spot Light Number of erythema with time after administration of the present invention Highest Number of erythema with time after administration of the present invention Highest 0 hours later 24 hours later 48 hours later After 72 hours 0 hours later 24 hours later 48 hours later After 72 hours 25 One 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 0 50 One 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 0 100 One 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 0

Animal Number Erythema and crust Edema Sum Normal skin Damaged skin Normal skin Damaged skin 24 hours later After 72 hours 24 hours later After 72 hours 24 hours later After 72 hours 24 hours later After 72 hours One 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 Sum 0 0 0 0 0 0 0 0 0

Table 1 and Table 2 shows the stability of the skin when applying and administering the hair growth promoting agent according to the present invention through the animal and clinical experiments in the laboratory (Dept. of Laboratory Animal Medicine, Chungbuk National University), Table 1 The results of experiments on guinea pigs to determine edema and skin irritation after the start of application through skin sensitization test for guinea pigs, and Table 2 shows the skin irritation test on rabbits to administer the present invention to normal skin and damaged skin. As a result, as confirmed by the above results, when the present invention was applied to the hair loss site, it was confirmed that there is no change in the skin tissue.

The present invention uses not only anti-inflammatory action by using ginseng and ginseng as a main component, but also increases the supply of oxygen and nutrients to the scalp cells, and complements the action of ginseng and ginseng by using apple juice, refined glucose, citric acid, and olive sugar together. Therefore, it strengthens the scalp's cellular activity, and can provide a hair growth promoting agent that does not impair the stability of the skin.

Claims (5)

In hair growth promoting agent, which is mainly composed of ginseng or ginseng, Mixed fermentation broth mixed with darin liquid (Material A) by adding Ogapi to purified water, and ginseng Darin liquid (Material B) by adding ginseng to purified water, and apple juice, refined glucose, citric acid, olive sugar, and purified water. (Material C) and a hair growth promoter characterized by mixing a separate purified water. The method of claim 1, The substance A, the substance B, the substance C, and the integer are hair growth promoters, characterized by mixing in a weight ratio of 3 to 8: 0.5 to 5: 30 to 50: 5 to 15. In the manufacturing method of hair growth promoting agent, the main ingredient of which is cucumber or ginseng, Heating the ogapi with purified water to obtain a substance A which is a dried ogapi darin solution, Heating ginseng with purified water to obtain substance B, which is darin ginseng darin liquid, Deeply fermenting apple juice, refined glucose, citric acid, olive sugar, and purified water to obtain substance C, a mixed fermentation liquid, Method for producing a hair growth promoter, characterized in that the step of mixing the substance A, substance B and substance C with a constant ratio with an integer. The method of claim 3, wherein Substance A and substance B is a method of producing a hair growth promoting agent, characterized in that the leg in low heat for 2 to 3 hours 30 minutes at a weight ratio of purified water 10 to 12 in the ginseng or ginseng 1. The method of claim 3, wherein Substance C is mixed with apple juice, refined glucose, citric acid, olive sugar, purified water in a weight ratio of 15-50: 0.1-1: 0.1-1: 0.1-1: 400-550, and then left at room temperature for 14-46 hours. A method for producing a hair growth promoting agent, characterized in that the deep fermentation.