CN103719496B

CN103719496B - A kind of leaves of Hawthorn lowering blood-fat and reducing weight health protection tea and preparation method thereof

Info

Publication number: CN103719496B
Application number: CN201310752943.5A
Authority: CN
Inventors: 逄海东; 逄海玲
Original assignee: Qingdao Hengbo Instrument Co Ltd
Current assignee: SHAANXI CENTURY HEALTH PHARMACY CO., LTD.
Priority date: 2013-12-31
Filing date: 2013-12-31
Publication date: 2015-09-30
Anticipated expiration: 2033-12-31
Also published as: CN103719496A

Abstract

The invention provides a kind of leaves of Hawthorn lowering blood-fat and reducing weight health protection tea, in described leaves of Hawthorn lowering blood-fat and reducing weight health protection tea, the parts by weight of various raw material are: leaves of Hawthorn 10 ~ 50 parts, the red sage root 10 ~ 20 parts, 10 ~ 20 parts, the dried rhizome of rehmannia, reticulate millettia 10 ~ 20 parts, rhizoma alismatis 10 ~ 20 parts, gynostemma pentaphylla 10 ~ 20 parts, motherwort 10 ~ 20 parts, elscholtiza 10 ~ 20 parts, the root bark of white mulberry 10 ~ 20 parts, peppermint 10 ~ 20 parts, Ligusticum wallichii 10 ~ 20 parts, root of Chinese trichosanthes 10 ~ 20 parts, the root of large-flowered skullcap 10 ~ 20 parts, Commeline communis 10 ~ 20 parts.Mountain plant leaf flavonoids have hypotensive, reduce peripheral vascular resistance, platelet aggregation-against, improve hemorheological property, eliminate oxygen radical, strengthen the pharmacological action such as hypoxia-bearing capability and diuresis.Leaf is planted on mountain, and in China various places, particularly Resources of The West Area In China is very abundant, add some promoting blood circulation and removing blood stasis, fat and serum triglyceride are all had to the Chinese medicine of obvious reducing effect, and can microcirculation be improved, people is made to be easy to accept, reach the function of daily health caring, more can reach effect of Weight-reducing and lipid-lowering preferably.

Description

A kind of leaves of Hawthorn lowering blood-fat and reducing weight health protection tea and preparation method thereof

Technical field

The present invention relates to the health products containing deriving from plant composition, particularly a kind of leaves of Hawthorn lowering blood-fat and reducing weight health protection tea and preparation method thereof.

Background technology

The high speed development of Modern Urban Living, also brings a series of rich man's disease.Wherein " three is high " and obesity are the primary enemies of puzzlement people." three high diseases " refers to hypertension, hyperglycaemia (diabetes) and hyperlipemia.Usually along with obesity.They be modern society derive from " rich man's disease ", possible individualism, also may be interrelated.As: diabetes patient is easy to suffer from hypertension or hyperlipemia simultaneously, and high fat of blood is the principal element of artery sclerosis formation and development, and arteriosclerotic's blood vessel elasticity difference aggravation blood pressure raises, so the later stage all defines " three high diseases ".Be what has statistics about three height, in the Chinese ten large causes of death, the death rate relevant to metabolic disease is just up to 35.7%, and the death toll relevant to " three is high " also accounts for 27% of total death toll.High fat of blood can cause blood vessel embolism; Hypertension can cause cerebral hemorrhage and rupture of blood vessel in brain; Hyperglycaemia can cause diabetes.The World Health Organization once clearly proposed, and prevented the first line of defence of cardiovascular disease from reducing " three is high " exactly and controlling " three is high ".A lot of diabetes patient is with hyperlipidemia, and therefore diabetes and hyperlipidemia, people call that sister is sick usually, and think that high fat of blood is the secondary disease of diabetes.The diabetic of about 40% has disorders of lipid metabolism according to statistics.Be characterized in that triglycerides increases to reduce with HDL.

Mountain is planted mountain contained by leaf and is planted leaf flavonoids and have pharmacological action widely, is particularly useful for cardiovascular system.Experimental study shows, mountain plant leaf flavonoids have hypotensive, reduce peripheral vascular resistance, coronary artery dilator, increase coronary flow, reduce MCO, cardiac stimulant, increase cardiac output, resist myocardial ischemia, platelet aggregation-against, improve hemorheological property, eliminate oxygen radical, fall the pharmacological actions such as excellent and constitution, enhancing hypoxia-bearing capability and diuresis.Clinical is all safe and effective for preventing and treating coronary disease and angina pectoris, hypertension, arrhythmia cordis and hyperlipidemia, atherosclerotic etc., is worthy of popularization.Leaf is planted on mountain, and in China various places, particularly Resources of The West Area In China is very abundant, has very high Development volue.

Leaves of Hawthorn has uniqueness, comprehensive, abundant nutrition, and medicinal characteristic is good, has the necessary multiple nutrients composition of human body, so be described as " the natural gold partner " of the mankind by worldwide nutrition scholar.We are except the few oily low sodium of eating attention, lighter, take relatively good after medicine still arrives regular examination in hospital according to the guidance of doctor.If conditions permit, take some health products or functional food is also good selection.Not greasy, lighter, have some green vegetables and fruit (preferably non-harmful, a lot of disease is all caused by agricultural chemicals, chemical fertilizer, hormone now), if domestic conditions pretty good can select some health foods or functional food more.The function of health products mainly improves brain blood circulation, adheres to physical training and suitably applies psychotropic agent.

The various health products sold on the market now, dragons and fishes jumbled together for medicine, great majority are the amusement of false propaganda, what have does not only have health-care components, also cause the huge injury of the person, therefore, search of health effective softening blood vessel method has very real significance, and softening blood vessel active material is the key that people expect to deal with problems always safely and effectively.Traditional Chinese medicine capable of reducing weight lipopenicillinase, having advantage that is nontoxic, that can be absorbed completely by organism, is the Main way that we study.There are reducing blood lipid, antibacterial, hypoglycemic, antioxidation in present market in the urgent need to developing one, and energy interference body is to the absorption of fat, promotes the product that the fat taken in excretes, and has advantage that is nontoxic, that can be absorbed completely by organism.

Summary of the invention

Technical problem to be solved by this invention is, the various health products sold on the market now, dragons and fishes jumbled together for medicine, great majority are the amusement of false propaganda, and what have does not only have health-care components, also causes the huge injury of the person, dragons and fishes jumbled together for most of diet products in present market, most just simple cathartic, allows people dewater in a large number, can cause huge injury to the person, therefore, the effective method of weight-reducing of search of health has very real significance.Experimental study shows, mountain plant leaf flavonoids have hypotensive, reduce peripheral vascular resistance, coronary artery dilator, increase coronary flow, reduce MCO, cardiac stimulant, increase cardiac output, resist myocardial ischemia, platelet aggregation-against, improve hemorheological property, eliminate oxygen radical, fall the pharmacological actions such as excellent and constitution, enhancing hypoxia-bearing capability and diuresis.Leaf is planted on mountain, and in China various places, particularly Resources of The West Area In China is very abundant, has very high Development volue; Add some promoting blood circulation and removing blood stasis, fat and serum triglyceride are all had to the Chinese medicine of obvious reducing effect, and can microcirculation be improved, make people be easy to accept, reach the function of daily health caring, more can reach effect of Weight-reducing and lipid-lowering preferably.

For solving above-mentioned technical barrier, the invention provides a kind of leaves of Hawthorn lowering blood-fat and reducing weight health protection tea, in described leaves of Hawthorn lowering blood-fat and reducing weight health protection tea, the parts by weight of various raw material are: leaves of Hawthorn 10 ~ 50 parts, the red sage root 10 ~ 20 parts, 10 ~ 20 parts, the dried rhizome of rehmannia, reticulate millettia 10 ~ 20 parts, rhizoma alismatis 10 ~ 20 parts, gynostemma pentaphylla 10 ~ 20 parts, motherwort 10 ~ 20 parts, elscholtiza 10 ~ 20 parts, the root bark of white mulberry 10 ~ 20 parts, peppermint 10 ~ 20 parts, Ligusticum wallichii 10 ~ 20 parts, root of Chinese trichosanthes 10 ~ 20 parts, the root of large-flowered skullcap 10 ~ 20 parts, Commeline communis 10 ~ 20 parts.

Described leaves of Hawthorn lowering blood-fat and reducing weight health protection tea, in leaves of Hawthorn lowering blood-fat and reducing weight health protection tea described in it, the parts by weight of various raw material can be: leaves of Hawthorn 10 ~ 30 parts, the red sage root 10 ~ 15 parts, 10 ~ 15 parts, the dried rhizome of rehmannia, reticulate millettia 10 ~ 15 parts, rhizoma alismatis 10 ~ 15 parts, gynostemma pentaphylla 10 ~ 15 parts, motherwort 10 ~ 15 parts, elscholtiza 10 ~ 15 parts, the root bark of white mulberry 10 ~ 20 parts, peppermint 10 ~ 20 parts, Ligusticum wallichii 10 ~ 20 parts, root of Chinese trichosanthes 10 ~ 20 parts, the root of large-flowered skullcap 10 ~ 20 parts, Commeline communis 10 ~ 20 parts.

Described leaves of Hawthorn lowering blood-fat and reducing weight health protection tea, in leaves of Hawthorn lowering blood-fat and reducing weight health protection tea described in it, the parts by weight of various raw material can also be: leaves of Hawthorn 10 ~ 40 parts, the red sage root 10 ~ 20 parts, 10 ~ 20 parts, the dried rhizome of rehmannia, reticulate millettia 10 ~ 20 parts, rhizoma alismatis 10 ~ 20 parts, gynostemma pentaphylla 10 ~ 20 parts, motherwort 10 ~ 20 parts, elscholtiza 10 ~ 20 parts, the root bark of white mulberry 10 ~ 15 parts, peppermint 10 ~ 15 parts, Ligusticum wallichii 10 ~ 15 parts, root of Chinese trichosanthes 10 ~ 15 parts, the root of large-flowered skullcap 10 ~ 15 parts, Commeline communis 10 ~ 15 parts.

For solving the problems of the technologies described above, the present invention also provides the preparation method of a kind of described leaves of Hawthorn lowering blood-fat and reducing weight health protection tea, and the preparation process of described leaves of Hawthorn lowering blood-fat and reducing weight health protection tea comprises following aspect:

A. the preparation of leaves of Hawthorn;

B. the leaves of Hawthorn Titian fried;

C. described other raw material soaking ethanol heating is extracted;

D. again the concentration of liquid medicine that surplus stock extracts is become granule, pulvis or paste;

E. concentrated granule, pulvis or paste are mixed with the leaves of Hawthorn prepared, sterilizing is prepared into health care medicinal tea.

In described step a, the leaves of Hawthorn of results can be cleaned the filament being cut into 1-2cm, airing, parch; The leaves of Hawthorn that airing is good is put into the pot that completes and goes green grass or young crops, complete 30-45 minute at 70-100 DEG C, then puts into large iron pan and stir-fry, and on first backward downwards, firmly wants evenly, when leaves of Hawthorn color starts jaundice, start little fire stir-fry 20-30 minute shaping;

In described step b, the leaves of Hawthorn of having fried can be put into fragrance extracting machine Titian 30-45 minute, naturally dry after taking out.

In described step c, other raw materials can be got add in the ethanol of 5-10 times amount and soak 1-2 hour, heating extraction 2 times, each 1-2 hour, removes supernatant, merge extract, 100-120 order filters, then is the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams, when ultrafiltrate reduced pressure concentration relative density is 80 DEG C 1.36 medicinal extract, heating is concentrated into paste, stand for standby use.

In described steps d, concentrated medicinal extract can be inserted in economic benefits and social benefits vacuum concentrator, when being concentrated into 90 DEG C, relative density is the concentrate of 1.05, sets to 0 ~ 5 DEG C of deepfreezes 24 hours; Refrigeration liquid is added the filter aid diatomite of 0.3%, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 1g crude drug amount; Paste after concentrated adds dextrin mediation and makes granule; Or convection drying makes pulvis.

In described step e, the leaves of Hawthorn made can be mixed with other raw materials of refinement, pack after ultraviolet ray sterilization bactericidal.

The technique effect that the present invention is useful is, dragons and fishes jumbled together for the various health products sold on the market now, great majority are the amusement of false propaganda, what have does not only have health-care components, also causes the huge injury of the person, most just simple cathartic, people is allowed to dewater in a large number, can cause huge injury to the person, therefore, the effective method of weight-reducing of search of health has very real significance.Experimental study shows, mountain plant leaf flavonoids have hypotensive, reduce peripheral vascular resistance, coronary artery dilator, increase coronary flow, reduce MCO, cardiac stimulant, increase cardiac output, resist myocardial ischemia, platelet aggregation-against, improve hemorheological property, eliminate oxygen radical, fall the pharmacological actions such as excellent and constitution, enhancing hypoxia-bearing capability and diuresis.Clinical is all safe and effective for preventing and treating coronary disease and angina pectoris, hypertension, arrhythmia cordis and hyperlipidemia, atherosclerotic etc., is worthy of popularization.Leaf is planted on mountain, and in China various places, particularly Resources of The West Area In China is very abundant, has very high Development volue; Add some promoting blood circulation and removing blood stasis, fat and serum triglyceride are all had to the Chinese medicine of obvious reducing effect, and can microcirculation be improved, make people be easy to accept, reach the function of daily health caring, more can reach effect of Weight-reducing and lipid-lowering preferably.

Detailed description of the invention

Along with industrialized development, the change of dietary structure, the improvement of living condition, the quantity of Overweight and obesity crowd worldwide increases rapidly, and in the trend of becoming younger, become global and have a strong impact on healthy epidemic disease, therefore, the effective method of weight-reducing of search of health has very real significance, and anti-obesity activity material is the key that people expect to solve problem of obesity always safely and effectively.Hypoglycemic method is a lot, has dietetic treatment, kinesiatrics, medicinal treatment and clinical treatment etc. and these methods more or less have weak point, and what have also easily causes side effect, as diarrhoea, apocleisis etc.And health treatment fat-reducing has easy to use, have no side effect, the features such as effect is remarkable, and extremely consumers.

Day by day flourishing due to economy, the continuous lifting of modern's living standard, cause people too much have deep love for enjoy, do not notice that the life style of oneself, behavioural habits, diet are had a liking for, thus the disease caused.Society with fast rhythm lives, the operating pressure of keen competition, serious threat is caused to the physical and mental health of modern, people more than half is made to be in sub-health state, show as: dizzy, nervous, weak, poor appetite, failure of memory, insomnia, indifferent to etc. to thing, in addition, long-term diet is unreasonable, that is: smart grain replaces coarse food grain completely, a large amount of three height (high heat, high protein, higher fatty acid), more than three, (anticorrisive agent is many, flavoring agent is many, hormone is many) agricultural chemicals residual in the absorption of food and food, chemical fertilizer stockpiling in vivo, add air, pollution of waterhead and amount of exercise less than normal, go down to make three high disease (hypertension for a long time like this, hyperglycaemia, high fat of blood), cardiovascular and cerebrovascular disease, cancers etc. so-called " modern civilization diseases " rise rapidly, and constantly rejuvenation, the serious health and lives jeopardizing the mankind.

Leaves of Hawthorn is rich in bioflavonoid, linoleic acid, chromium element.Crataegutt not only can effectively promoting blood circulation and removing blood stasis, embolism resistance, reducing blood lipid, hypotensive, reduce cholesterol, reduce blood sugar, the composition of blood is purified, but also the fragility of microcirculation, reduction capillary can be improved, reduce its permeability, impaired vascular wall can be repaired.

The red sage root is bitter, is slightly cold.The thoughts of returning home, Liver Channel.Stasis-dispelling and pain-killing, activating blood to promote menstruation, clear away heart-fire relieving restlessness.For irregular menstruation, through closing dysmenorrhoea, a lump in the abdomen causing distension and pain, and chest ventral spine pain, hot numbness pain, sore swells and ache, dysphoria and insomnia.For sternal rib hypochondriac pain, arthralgia due to wind-dampness, abdominal mass lumps, and sore swells and ache, fall fall forward grieved, irregular menstruation, through closing dysmenorrhoea, postpartum stasis of blood pain etc.Treatment sternal rib pain, abdominal mass caking, and irregular menstruation, through amenorrhoea pain, there is good effect." detailed outline " carries: the red sage root, and by " the sensible opinion of married woman " cloud, gynecopathy controlled by Siwu Tang, pays no attention to antenatal postpartum, how many through water, all can be general, and the only taste red sage root falls apart, and cures mainly identical with it.The lid red sage root can break place blood, mends new blood, peaceful tire, and fall stillborn foetus, only metrorrhagia stagnant under, menstruation regulating arteries and veins.Main Compositions of Radix Salviae Miltiorrhizae tanshinone has hemangiectasis, improves circulation, removes the effects such as intravascular coagulation, has effect of invigorating blood circulation trace, and can promote that liver blood circulates, be beneficial to liver cell regeneration.

The dried rhizome of rehmannia: the dried rhizome of rehmannia is also radix rehmanniae recen, the fresh or dry block root of Scrophulariaceae herbaceos perennial glutinous rehmannia Rehmannia glutinosaLibosch..Heat-clearing, promote the production of body fluid, moisturize, laxation, the broken stasis of blood, raw new, pain relieving, menstruation regulating, the metal-inflicted wound stasis of blood, cool blood, hemostasis; The effect of fresh rehmannia root and radix rehmanniae recen is different.Fresh rehmannia root clearing heat and promoting fluid, can stop blooding and cool blood, be often for consumption of YIN caused by febrile disease, the illnesss such as haematemesis, abscess of throat, the deep red polydipsia of tongue, a spot dermexanthesis and nosebleed heat.Relative to fresh rehmannia root, radix rehmanniae recen is heat clearing and blood cooling, also can promote the production of body fluid, all right yin-nourishing, is used for treatment yin asthenia generating intrinsic heat, hectic fever due to yin labor heat, the deep red polydipsia of tongue, sends out the problems such as spot dermexanthesis.The dried rhizome of rehmannia is cold in nature, and function is enriching yin and nourishing kidney.Not only promote the production of body fluid to quench thirst and heat clearing and blood cooling, also have effect to metrorrhagia, irregular menstruation, fetal irritability, constipation etc., every blood system has the people of thermal burn the moon, can often take.If want to treat warm heat disease, qingying decoction can be done with the dried rhizome of rehmannia; If the later stage for the treatment of warm disease, because waste heat does not also disappear to the greatest extent, the dried rhizome of rehmannia should be used for boiling Qinghao Biejia Tang; In addition, contain for blood-head poison, macula purple is black, and the serious heat of warm heat disease enters the symptom of ying blood, can take the Sisheng Wan that the dried rhizome of rehmannia is made; General want nourishing Yin and promoting production of body fluid to treat interior heat quenches one's thirst with constipation, the once liquid soup that the dried rhizome of rehmannia boils should be eaten.

Reticulate millettia property is bitter, sweet, temperature.Return liver, kidney channel, enrich blood, invigorate blood circulation, dredging collateral.For irregular menstruation, the deficiency of blood is sallow, paralysis and numbness, and arthralgia due to wind-dampness is activated blood and relaxed tendons; Nourishing blood for regulating menstruation, supplementary Amplifications of the Compendium of Materia Medica carries it can cure numb in every limb; Quadriplegia; Arthralgia due to wind-dampness; Women has through uncomfortable; Dysmenorrhoea.External application is the gynaecology's good medicine activated blood circulation and dispersed blood clots.

Ligusticum wallichii is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, Main Cultivation in Sichuan, Yunnan, Guizhou, Guangxi, the ground such as Hubei.The pungent temperature of Ligusticum wallichii is fragrant dry, walks and does not keep, can go loose, and the up mountain peak that reaches is pushed up; Enter blood system again, descendingly reach the sea of blood.Promoting blood circulation effect is extensive, the suitable various illness of stagnation of blood stasis; Wind-expelling pain-stopping, effectiveness is excellent, can control a disease such as wind headache, arthralgia due to wind-dampness.It is gas medicine in blood that former times people calls Ligusticum wallichii, the functions such as pungent loose, the Xie Yu of its residence of dangerous speech, sensible, pain relieving.To effect 2.1 pairs of action of the heart Ligusticum wallichii decoctions of cardiovascular system to Isolated Toad and frog heart, concentration at 10-5-10-4 time make that contractive amplitude increases, heart rate is slightly slow.By the test of EnglmannShi method, Ligusticum wallichii 20 or 30g/kgig, also make frog heart amplitude in place increase, decreased heart rate; With 40g/kgig, then the frog heart can be made to stop fighting.Ligustrazine iv also has cardiotonic to anesthetized dog, with increased heart rate.Remove vagal heart, significant reaction is still had to ligustrazine.Vertebral artery injects larger dose ligustrazine, and its Cardiovascular is not obvious.Award inderal or reserpinization in advance, can eliminate ligustrazine completely to action of the heart, therefore ligustrazine is to action of the heart, may be by caused by sympathetic nerve indirect excitation heart B acceptor." detailed outline ": eliminating dampness, antidiarrheal dysentery, activating QI to alleviate the depression.Rhizome of chuanxiong Qiong, in blood, gas medicine also, liver bitter anxious with pungent benefit it, therefore deficiency of blood person should it; Pungent to fall apart it, therefore obstruction of the circulation of vital energy person should it.

Rhizoma alismatis (rhizome) is one of traditional Chinese medicine.Theory of traditional Chinese medical science thinks that it is cold in nature, has effect of clearing damp and promoting diuresis.Modern medicine study, rhizoma alismatis can reduce serum total cholesterol and triacylglycerol content, slows down atherogenesis; Rhizoma alismatis and preparation modern times thereof are also used for the treatment of auditory vertigo, dyslipidemia, seminal emission, fatty liver and diabetes etc.The fat-soluble part of rhizoma alismatis has obvious norcholesterol effect and study of anti-atherogenic effect to experimental hypercholesterolemicrabbits rabbit, by the acetic acid esters of the alisol A be wherein separated, B and alisol A, B, C, except alisol B, there is the norcholesterol effect shown.Content with 0.1% adds in the feed of experimental atherosclerosis rats, and cholesterolemia can be made to decline more than 50%, wherein the strongest with the effect of alisol A-24-acetic acid esters.The ethanol extract of rhizoma alismatis, the ethyl acetate extract etc. of ethanol extract, have effect for reducing blood fat to experimental hypercholesterolemicrabbits rabbit and rat.Ethyl acetate extract is the strongest with its residual fraction effect be insoluble in acetic acid one water.Ethyl acetate extract oral 1g/kg every day, also has obvious norcholesterol effect to raising with the normal rat of normal diet.Prove by coordination list notation method, alisol A has the ability suppressing mouse small intestine esterified cholesterol, and the absorptivity of cholesterol in rat small intestine can be made to reduce by 34%, but do not affect linoleic absorption gynostemma pentaphylla to find through modern medicine study, gynostemma pentaphylla principle active component is polysaccharide, flavonoids, saponins and microelement kind, its effect mainly promotes body fat class metabolism, nutrition human body cell, there is good detoxicating, relieving inflammation effect simultaneously, be widely used in high fat of blood, fatty liver, fat, constipation, insomnia, hepatitis B, chronic airway inflammation (sphagitis, enterogastritis etc.) treatment and health care.

The root bark of white mulberry is the root skin of moraceae plants mulberry Moms alba L..Main product in Anhui, Henan, Zhejiang, Jiangsu, the ground such as Hunan.Effect: removing heat from lung and relieving asthma, inducing diuresis for removing edema.Cough for lung heat and breathe heavily, the edema of the face, the diseases such as difficult urination." property of medicine opinion ": make, flat.Can control lung qi breathes heavily full, aqueous vapor edema, and main wound is exhausted, dredging water passages, and disappear aqueous vapor, the headache of consumptive disease visitor heat, interior tonifying for the deficiency." Japan hanako materia medica ": temperature, in tune, lower gas.Dissolving phlegm is quenched the thirst, sharp intestine and small intestine, appetizing, lower food, and kill abdomen and hide worm, only cholera is vomited and diarrhoea.

Root of Chinese trichosanthes is the root of cucurbitaceous plant Chinese juniper beach wormwood, is a kind of Chinese medicine, and be clearing heat-fire class medicine, its concrete effect is clearing heat-fire, promotes the production of body fluid to quench thirst, and apocenosis is subsided a swelling.Cure mainly: control pyreticosis thirsty, quench one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle are swollen, hemorrhoid impotence.For treatment diabetes, conventional it and drugs for nourishing yin with the use of, to reach the effect for the treatment of both principal and secondary aspect of disease." book on Chinese herbal medicine converge with speech ": root of Chinese trichosanthes, it is hot and suffocating to move back the five internal organs, and as internal heat is contained and dry tongue and mouth, lung-fire is contained and the swollen larynx numbness of pharynx, and spleen fire is contained and dispute tooth swells, and convulsive seizure due to phlegm-fire is contained and cough is not peaceful.Walk note if the side of body of irascibility is swollen, the hectic fever due to yin dysphoria with smothery sensation of kidney fire, or ulcer is not burst, and hot poison does not fall apart, or five subcutaneous ulcer yellow skin and eyes, and if if the pouring of little water is puckery, be all intimately caused by pent-up, convulsive seizure due to phlegm-fire, falls in only this agent energy relieving stagnation, and can control it.Its property is sweet cold again, kindly can control thirsty, and control empty thirsty from tonic, control fire from the medicine of a cold nature thirsty, control yearningly strongly fragrant from gas medicine, controlling polydipsia from blood medicine, is control thirsty key medicine also.

The root of large-flowered skullcap: the root of large-flowered skullcap has heat-clearing and damp-drying drug, cool blood is antiabortive, detoxicating functions.Cure mainly warm heat disease, the infection of the upper respiratory tract, cough with lung heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, hot eyes, fetal irritability, hypertension, carbuncle swell the diseases such as furuncle sore.The clinical practice of the root of large-flowered skullcap is antibacterial not worse than the coptis, and does not develop immunity to drugs.We are by the strong feature of broad-spectrum antibacterial action, are used in fungal culture miscellaneous bacteria and infect special severe, fine by root of large-flowered skullcap extract effect." Bencao Jingshu ": the root of large-flowered skullcap, its property is respectful clearly, so evil removing: bitter is so eliminating dampness; Cold sensation of the genitalia is so victory warm, therefore main all heat.All hot persons, heat symptoms caused by an exopathgen with all over heat also, jaundice, intestines are out-of-the-way, let out dysentery, and the disease of all damp and hot victory also, analyses it, then all diseases are from recover.Bitter cold can except damp and hot, thus small intestine profit and water from by, source is clearly then flowed also clean.The blood person of closing, real heat is at blood system, and instant heating human blood room, make us obstructed through closing, damp and hot solution, then Ying Qi clearly and voluntarily also.Dislike sore subcutaneous ulcer erosion person, blood-head then stays knot, and is that the carbuncle stain that swells is also rotten: fiery ulcer person, also, cool blood heat extraction, then self-healing also for internal heat blood trouble.The root of large-flowered skullcap has antiallergic action and antiinflammatory action: the anaphylaxis contractile response that baicalin contained by the root of large-flowered skullcap and baicalein can obviously suppress sensitized guinea pig rat small intestine in vitro and isolated tracheal to produce antigen, to passive general allergy and the cavy passivity skin allergic reaction of cavy and mouse, baicalin and baicalein also have inhibitory action.The root of large-flowered skullcap has refrigeration function, and most test proves, the effective ingredient baicalein of the root of large-flowered skullcap has refrigeration function.The root of large-flowered skullcap has detoxication, and baicalin has obvious detoxication, and this may be that baicalin decomposites glucuronic acid due under the effect of glucuronidase, and caused by being combined with multiple poisonous substance.The LD50 that baicalin 10 milligrams can improve strychnine reaches 2.5 times, and the hepatic glycogen content of carbon tetrachloride poisoning mouse is increased.

Commeline communis: binomial nomenclature: Commelina communis.For swelling diuretic, clearing heat and detoxicating good medicine, there is good efficacy to sty, pharyngitis, tonsillitis, cervical erosion, abdomen snake bite in addition.Herb is used for flu, oedema, urinary infection, pharyngitis, acute tonsillitis, chordapsus, dysentery, sore furuncle poison " Nujiang medicine ".[Dai Nationality's medicine] handkerchief is breathed out difficult: row water, removing pattogenic heat from the blood and toxic material from the body " Dai medicine ".[anaesthetic] herb cures mainly oedema, beriberi, difficult urination, nosebleed epistaxis, hematuria, metrorrhagia, flu, abscess of throat, erysipelas, mumps, icterohepatitis, hot dysentery, and carbuncle swells sore furuncle, venomous snake bite " illiteracy plants medicine will ".

Peppermint is one of Chinese conventional Chinese medicine.It is pungent cool property sweating antipyretic medicine, controls influenza, the disease such as headache, hot eyes, body heat, throat, gum swell and ache.External application can control neuralgia, pruitus, fash and eczema etc.The peppermint of light friend Greenhouse Fruit Picking is again the fresh vegetable on dining table in the Spring Festival.Clearly good to eat.Usually with peppermint for tea, clear away heart-fire improving eyesight.

Elscholtiza another name perfume (or spice) is eaten, vanilla, Latin literary fame HERBA MOSLAE. Chinese medicine name, and energy sweating relieving summer-heat, row water is loose wet, during warm stomach is adjusted.Cure mainly: the cold drink of Xia Yue sense is cold, and have a headache and fever, aversion to cold is lossless, and the feeling of stuffiness in chest is suffered from abdominal pain, vomiting and diarrhoea, oedema, beriberi." Mingyi Bielu ": taste is pungent, tepor.Cure mainly cholera, suffer from abdominal pain, tell down, aproll swells." Japan hanako materia medica ": nontoxic, lower gas, except dysphoria with smothery sensation, treats inverse cold air of vomitting." Kaibao Bencao ": taste is pungent, tepor.Main abdominal pain due to acute vomiting and diarrhea is told down, and aproll swells.

Motherwort: be the herb of labiate motherwort.1 year or biennial herb, summer-flowering.Be born in hill wasteland, ridge, meadow etc.Whole nation most area all has distribution.Pluck when the non-standard-sized sheet of riotous growth flower in summer.Edible effect: taste is arduous, cool.Invigorate blood circulation, silt of dispelling, menstruation regulating, disappear water.Treatment menoxenia, threatened abortion is had difficult labour, placenta retension, postpartum anemic fainting, abdominal pain due to blood stasis, and metrorrhagia and metrostaxis, rushes down blood at hematuria, and carbuncle swells sore.

Specific embodiment 1:

First by leaves of Hawthorn frying, Titian.

Again by all the other raw material reds sage root, the dried rhizome of rehmannia, reticulate millettia, rhizoma alismatis, gynostemma pentaphylla, motherwort, elscholtiza, the root bark of white mulberry, peppermint, Ligusticum wallichii, root of Chinese trichosanthes, the root of large-flowered skullcap, Commeline communis is extracted, and makes paste, granule or pulvis.

Two kinds of extract mixing, ultraviolet radiation for sterilizing and disinfecting packs.

Specific embodiment 2:

Get leaves of Hawthorn 5000g to clean, the leaves of Hawthorn of results is cleaned the filament being cut into 1-2cm, airing, parch; The leaves of Hawthorn that airing is good is put into the pot that completes and goes green grass or young crops, complete 30-45 minute at 70-100 DEG C, then puts into large iron pan and stir-fry, and on first backward downwards, firmly wants evenly, when leaves of Hawthorn color starts jaundice, start little fire stir-fry 20-30 minute shaping; The leaves of Hawthorn of having fried is put into fragrance extracting machine Titian 30-45 minute, naturally dry after taking out.

Get other raw material reds sage root 1500g, dried rhizome of rehmannia 1500g, reticulate millettia 1500g, rhizoma alismatis 1500g, gynostemma pentaphylla 1500g, motherwort 1500g, elscholtiza 1500g, root bark of white mulberry 1500g, peppermint 1500g, Ligusticum wallichii 1500g, root of Chinese trichosanthes 1500g, root of large-flowered skullcap 1500g, Commeline communis 1500g, add in the ethanol of 5-10 times amount and soak 1-2 hour, heating extraction 2 times, each 1-2 hour, remove supernatant, merge extract, 100-120 order filters, be the ultrafiltration post ultrafiltration of 5000-10000 again through the molecular weight that dams, when ultrafiltrate reduced pressure concentration relative density is 80 DEG C 1.36 medicinal extract, heating is concentrated into paste, stand for standby use, become component 2.Component 1 and component 2 mixing are inserted in economic benefits and social benefits vacuum concentrator, when being concentrated into 90 DEG C, relative density is the concentrate of 1.05, sets to 0 ~ 5 DEG C of deepfreezes 24 hours; Refrigeration liquid is added the filter aid diatomite of 0.3%, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 1g crude drug amount, then adds dextrin and is in harmonious proportion, make granule, and the leaves of Hawthorn of mixing Titian, ultraviolet disinfection, packs and get final product.

Specific embodiment 3:

Get leaves of Hawthorn 3500g to clean, be cut into the filament of 1-2cm, airing, parch; The leaves of Hawthorn that airing is good is put into the pot that completes and goes green grass or young crops, complete 30-45 minute at 70-100 DEG C, then puts into large iron pan and stir-fry, and on first backward downwards, firmly wants evenly, when leaves of Hawthorn color starts jaundice, start little fire stir-fry 20-30 minute shaping; The leaves of Hawthorn of having fried is put into fragrance extracting machine Titian 30-45 minute, naturally dry after taking out; Get other raw material reds sage root 1300g, dried rhizome of rehmannia 1300g, reticulate millettia 1300g, rhizoma alismatis 1200g, gynostemma pentaphylla 1300g, motherwort 1200g, elscholtiza 1200g, root bark of white mulberry 1300g, peppermint 1200g, Ligusticum wallichii 1200g, root of Chinese trichosanthes 1200g, root of large-flowered skullcap 1200g, Commeline communis 1200g, other raw materials are put into 10 times of water gagings, heating and refluxing extraction 2 times, each extraction time is 1 ~ 2 hour, 100-120 order filters, be the ultrafiltration post ultrafiltration of 5000-10000 again through the molecular weight that dams, when ultrafiltrate reduced pressure concentration relative density is 80 DEG C 1.36 medicinal extract, heating be concentrated into paste; Become component 2; Get component 1 and component 2 mixes, filter; The filtrate of filtration inserted in economic benefits and social benefits vacuum concentrator, when being concentrated into 90 DEG C, relative density is the concentrate of 1.05, sets to 0 ~ 5 DEG C of deepfreezes 24 hours; Refrigeration liquid is added the filter aid diatomite of 0.3%, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 1g crude drug amount, makes pulvis, and the leaves of Hawthorn of mixing Titian, ultraviolet disinfection, packs and get final product.

Pharmacological toxicity is tested

One, skin irritation test

1, experimental technique

Hair remover is evenly coated by guinea pig back backbone both sides, makes unhairing scope about 20 square centimeters.Clean hair remover returns cage to observe 24 hours, often organizes cavy and is coated with the present invention 4,8 and 12g respectively, and respectively containing crude drug 92mg, 184mg and 368mg, another group is coated with the every twice-daily of solvent 0.8ml, continuous one week, after experiment terminates, cavy is put to death, the heart, liver, kidney and depilation skin do pathological examination.

2, result

Above-mentioned three groups of medication cavy trunks depilation district, having no local skin has oedema, hyperemia, erythema, blutpunkte and ulcer.Medication group cavy chroma of hair, ingest, the control group no significant difference such as four limbs are movable, histopathologic examination, the administration group heart, liver, kidney and depilation skin with contrast word more also no significant difference.

Result is pointed out, and the present invention, without local irritant effect, also has no general toxicity performance.Show invention formulation use safety.

Two, animal acute toxicity test research:

The present invention, through trial test, can not measure LD50, therefore measures maximum dosage-feeding.Adopt rectal delivery, the maximum dosage-feeding on the one recording mouse is 62.7g/kg (in medicinal powder), be about 1567.5 times (people is in 60kg) intending clinical people's consumption, the maximum dosage-feeding 62.7g/kg (in medicinal powder) on the one of rat, is about 1567.5 times that intend clinical people's consumption.The equal Continuous Observation of animal used as test one week, its outward appearance sign, the state of mind, diet, drinking-water, ight soil etc. are showed no obvious abnormalities.At the end of experiment, all healthy survival of animal, body weight increases.

Three, long-term toxicity test for animals research:

This test establishes medicine of the present invention high, in, low dose group and Matrix controls group, blank group, rectal delivery is adopted to give rat, dosage is respectively 3.2, 2.4 and 1.6g/kg (in medicinal powder), be equivalent to intend 80 of clinical patient consumption [0.04g (medicinal powder)/kg], 60 and 40 times, successive administration 2 months, in administration process, the body weight of each administration group and matrix group rat, dietary amount, outward appearance sign, behavioral activity, the state of mind, hair color, ight soil proterties compares with blank group, no significant difference (P>0.05), the weight of animals increasing value and Main Organ Coefficients and blank group comparing difference are not significantly (P>0.05), hematology and the indivedual index of blood parameters check result administration group and blank group comparing difference are significantly (P<0.05), but convalescence terminates rear discrepant hematology and blood parameters has recovered normal all, other indexs and blank comparing difference are not significantly (P>0.05), administration phase and convalescence histological examination high dose group animal main organs compare with blank group and have no notable difference, have no slowness toxicity to occur.

Pharmacological experiment:

Research the present invention merges the hypoglycemic lipid-lowering effect of hyperlipidemia to diabetes B.Method: adopt high lipid food associating Streptozotocin (streptozoto cin, STZ) 30mg/kg lumbar injection, set up diabetes B and merge olive Antihyperlipidemia capsule, look into fasting blood-glucose (fasting bloo d gluco se, FBG), T-CHOL (total cho lestero l, T C), triglycerides (tr iglycer ide, TG), ALT (alanine aminotr ansfer ase, ALT).36 rats after modeling success are divided into 3 groups at random: the present invention 1 group (3ml/kg benefit fat health); The present invention 2 groups (9ml/mg benefit fat health); Western medicine group (Metformin hydrochloride 2ml/kg+ fenofibrate 3ml/kg).By design gastric infusion, 1 time/d.Successive administration checks FBG, TC, TG, ALT after February, observes

Curative effect.Normal group 10 rats give normal saline.Result shows the present invention significantly can reduce FBG, TC and TG, and less to liver function impairment.The present invention merges hyperlipidemia to diabetes B remarkable hypoglycemic curative effect.

1 materials and methods

1.1 animals used as test, rearing conditions and feed

SPF level SD male rat 55, body weight 155 ~ 235g, thered is provided by affiliated hospital of Shandong University Experimental Animal Center, raise at affiliated hospital of Shandong University experimental center SPF level Animal Lab., keep the room temperature of 24 DEG C ± 1 DEG C in animal housing, humidity 60% ± 10%, freely drink water, take food, adopt the alternately illumination of 12h light and shade, change weekly 3 water, change 2 bedding and padding.Rat chow diet, is derived from Center for Disease Control of Hubei Province.High lipid food: 62% chow diet, 4% fructose, 12% yolk powder, 22% lard, fully grinds to form strip after mixing, originates from Shandong University's biology laboratory.

1.2 reagent

Vessel used to hold grain at the imperial sacrifice urea assistant rhzomorph (str eptozotocin, ST Z) powder-injection: Sigma company produces, and is made into the application liquid of 3mg/ml, mixes 5min with oscillator during experiment with ice-cold pH4.50.1mmo l/L citrate buffer solution, after dissolving mixing completely, inject immediately.

1.3 method

SPF level SD male rat 55, body weight 155 ~ 235g, after adaptability raises 1 week, separates 10 rats at random as Normal group, feeds with full nutrition feed, does not do any process.All the other 45 rats high lipid food feeds fasting 12h after 1 month, gives disposable celiac injection STZ30mg/kg.After 72h, tail vein measures blood sugar, blood fat, liver function.The rat of random blood sugar 18mmol/L is modeling success.Finally become mould 36, be divided into 3 groups at random according to blood sugar height: the present invention 1 group, the present invention 2 groups and Western medicine group.Give the present invention 1 group (3ml/kg is prepared by detailed description of the invention 2) respectively, the present invention 2 groups (9ml/mg), Western medicine group (Metformin hydrochloride 2ml/kg+ fenofibrate 3ml/kg) gavage is treated, 1 time/d.Period gives high glucose and high fat forage feed always.Normal group gives normal saline.Fasting blood-glucose (fast ing b1ood g lucose is checked after February, FBG), T-CHOL (to tal cho lesterol, TC), triacylglycerol (t rigly ceride, TG), ALT (alanine aminot ransferase, ALT), observe the curative effect.

1.4 statistical procedures

Data mean standard deviation (-x ± s) represents, adopts SPSS13.0 statistical software, and own control adopts independent t test, and enumeration data adopts X ²inspection.P<0.05 has statistical significance.

2 results

Before and after the present invention 1 group, the present invention 2 groups, the treatment of Western medicine group, indices contrast is visible: FBG, TC, T G of 3 groups all has obvious reduction, and difference has statistical significance (t=4.891, P<0.01).All decreased by the visible 3 groups of liver function ALT of table 1, difference has statistical significance (t=3.062, P<0.01).It is more visible that the present invention 1 group, the present invention 2 groups and Western medicine group treat rear indices: FBG, T C all has reduction, but not statistically significant (P>0.05), the reduction of the present invention 1 group and the present invention 2 groups of TG is obviously better than Western medicine group, there is statistical significance (t=2.449, P<0.05), and the recovery of liver function ALT is better than Western medicine group, there is statistical significance (t=6.518, P<0.01).

After 3 groups of treatments, indices contrasts visible with control group: FBG, TG of 3 groups for the treatment of groups more all have rising with control group, but not statistically significant (P>0.05), and T C declines obviously, have statistical significance (t=2.566, P<0.01), the liver function of 3 groups for the treatment of groups all has infringement, the index of ALT more all has rising with control group, there is statistical significance (t=2.798, P<0.01), in table 1.

Table 1 respectively organizes FBG, TC, T G, ALT level (mmo l/L ,-x ± s) before and after treating

Note: compare before and after each group treatment, #P<0.05, ##P<0.01; Compare with Western medicine group, * P<0.05, * * P<0.01; Compare with control group, $ P<0.05, $ $ P<0.01

3 discuss

Namely traditional Chinese medicine was described the symptom of diabete (diabetes), prognosis and complication etc., and has abundant treatment content before more than 2000 years.The present invention is on diagnosis and treatment basis, and in conjunction with to the pathogenetic profound understanding of diabetes B hyperlipidemia, the length and the clinical experience for many years that absorb many families created.Peppermint, rhizoma alismatis, bighead atractylodes rhizome strengthening the spleen and reducing phlegm in the prescription of benefit fat health, the nourshing kidney of elscholtiza tonifying liver, rhizoma alismatis is reduced phlegm and lets out turbid, and reticulate millettia promoting blood circulation, peppermint replenishes qi to invigorate the spleen.In addition, research shows, peppermint has and reduces blood sugar, plasma viscosity, packed cell volume, fibrinogen preferably, Antiaggregating activity on platelet, improves the effect of immunity of organisms; Elscholtiza has obvious reducing blood lipid, study of anti-atherogenic effect; Rhizoma alismatis then can promote transhipment and the removing of fat, suppresses the absorption of lipid.It is remarkable that the present invention also demonstrates leaves of Hawthorn hypoglycemic lipid-lowering effect by zoopery, close with the Western medicine group curative effect of fenofibrate and Metformin hydrochloride.And the present invention has Mutiple Targets, hypoglycemic, lipopenicillinase lasting medicine, the advantages such as liver and kidney dysfunction is little, integrally-regulated function of human body.

In recent years, along with improving constantly of people's living standard, the disease incidence such as diabetes, coronary heart disease increases day by day.Chinese herbal medicine effect is stablized, few side effects, and research has the Chinese herbal medicine of softening blood vessel effect, can provide more method for clinical treatment diabetes, hyperlipidemia.Mountain is planted mountain contained by leaf and is planted leaf flavonoids and have pharmacological action widely, is particularly useful for cardiovascular system.Experimental study shows, mountain plant leaf flavonoids have hypotensive, reduce peripheral vascular resistance, coronary artery dilator, increase coronary flow, reduce MCO, cardiac stimulant, increase cardiac output, resist myocardial ischemia, platelet aggregation-against, improve hemorheological property, eliminate oxygen radical, fall the pharmacological actions such as excellent and constitution, enhancing hypoxia-bearing capability and diuresis.Clinical is all safe and effective for preventing and treating coronary disease and angina pectoris, hypertension, arrhythmia cordis and hyperlipidemia, atherosclerotic etc., is worthy of popularization.Leaf is planted on mountain, and in China various places, particularly Resources of The West Area In China is very abundant, has very high Development volue.In sum, leaves of Hawthorn has good lowering blood-fat and reducing weight health-care effect, can be used for prevention, treatment diabetes and hyperlipidemia clinically.

Claims

1. a leaves of Hawthorn lowering blood-fat and reducing weight health protection tea, is characterized in that, the Chinese medicine material of described leaves of Hawthorn lowering blood-fat and reducing weight health protection tea is made up of the bulk drug of following parts by weight: leaves of Hawthorn 10 ~ 50 parts, the red sage root 10 ~ 20 parts, 10 ~ 20 parts, the dried rhizome of rehmannia, reticulate millettia 10 ~ 20 parts, rhizoma alismatis 10 ~ 20 parts, gynostemma pentaphylla 10 ~ 20 parts, motherwort 10 ~ 20 parts, elscholtiza 10 ~ 20 parts, the root bark of white mulberry 10 ~ 20 parts, peppermint 10 ~ 20 parts, Ligusticum wallichii 10 ~ 20 parts, root of Chinese trichosanthes 10 ~ 20 parts, the root of large-flowered skullcap 10 ~ 20 parts, Commeline communis 10 ~ 20 parts.

2. leaves of Hawthorn lowering blood-fat and reducing weight health protection tea according to claim 1, it is characterized in that, the Chinese medicine material of described leaves of Hawthorn lowering blood-fat and reducing weight health protection tea is made up of the bulk drug of following parts by weight: leaves of Hawthorn 10 ~ 30 parts, the red sage root 10 ~ 15 parts, 10 ~ 15 parts, the dried rhizome of rehmannia, reticulate millettia 10 ~ 15 parts, rhizoma alismatis 10 ~ 15 parts, gynostemma pentaphylla 10 ~ 15 parts, motherwort 10 ~ 15 parts, elscholtiza 10 ~ 15 parts, the root bark of white mulberry 10 ~ 20 parts, peppermint 10 ~ 20 parts, Ligusticum wallichii 10 ~ 20 parts, root of Chinese trichosanthes 10 ~ 20 parts, the root of large-flowered skullcap 10 ~ 20 parts, Commeline communis 10 ~ 20 parts.

3. leaves of Hawthorn lowering blood-fat and reducing weight health protection tea according to claim 1, it is characterized in that, the Chinese medicine material of described leaves of Hawthorn lowering blood-fat and reducing weight health protection tea is made up of the bulk drug of following parts by weight: leaves of Hawthorn 10 ~ 40 parts, the red sage root 10 ~ 20 parts, 10 ~ 20 parts, the dried rhizome of rehmannia, reticulate millettia 10 ~ 20 parts, rhizoma alismatis 10 ~ 20 parts, gynostemma pentaphylla 10 ~ 20 parts, motherwort 10 ~ 20 parts, elscholtiza 10 ~ 20 parts, the root bark of white mulberry 10 ~ 15 parts, peppermint 10 ~ 15 parts, Ligusticum wallichii 10 ~ 15 parts, root of Chinese trichosanthes 10 ~ 15 parts, the root of large-flowered skullcap 10 ~ 15 parts, Commeline communis 10 ~ 15 parts.

4. the preparation method of leaves of Hawthorn lowering blood-fat and reducing weight health protection tea as described in any one of claims 1 to 3 item, it is characterized in that, the preparation process of described leaves of Hawthorn lowering blood-fat and reducing weight health protection tea comprises:

A. the preparation of leaves of Hawthorn: the leaves of Hawthorn of results is cleaned the filament being cut into 1-2cm, airing, parch; The leaves of Hawthorn that airing is good is put into the pot that completes and goes green grass or young crops, complete 30-45 minute at 70-100 DEG C, then puts into large iron pan and stir-fry, and on first backward downwards, firmly wants evenly, when leaves of Hawthorn color starts jaundice, start little fire stir-fry 20-30 minute shaping;

B. the leaves of Hawthorn Titian fried;

C. the heating of other raw material soaking ethanol is extracted;

D. again the concentration of liquid medicine that step c extracts is become granule, pulvis or paste;

5. the preparation method of leaves of Hawthorn lowering blood-fat and reducing weight health protection tea according to claim 4, is characterized in that, in described step b, the leaves of Hawthorn of having fried is put into fragrance extracting machine Titian 30-45 minute, naturally dries after taking out.

6. the preparation method of leaves of Hawthorn lowering blood-fat and reducing weight health protection tea according to claim 4, is characterized in that, in described step c, get other raw materials to add in the ethanol of 5-10 times amount and soak 1-2 hour, heating extraction 2 times, each 1-2 hour, removes supernatant, merge extract, 100-120 order filters, then is the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams, when ultrafiltrate reduced pressure concentration relative density is 80 DEG C 1.36 medicinal extract, heating is concentrated into paste, stand for standby use.

7. the preparation method of leaves of Hawthorn lowering blood-fat and reducing weight health protection tea according to claim 4, is characterized in that, in described step e, the leaves of Hawthorn made mixed with other raw materials of refinement, pack after ultraviolet ray sterilization bactericidal.