CN103549072B - Vital energy-benefiting brain-boosting tea and preparation method thereof - Google Patents
Vital energy-benefiting brain-boosting tea and preparation method thereof Download PDFInfo
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Abstract
The invention discloses vital energy-benefiting brain-boosting tea and a preparation method thereof. The vital energy-benefiting brain-boosting tea comprises the following raw materials: 8g-13g of medlar, 9g-13g of astragalus membranaceus, 14g-18g of angelica, 9g-14g of roots of common peony, 9g-12g of cassia twigs, 12g-15g of safflower carthamus, 9g-14g of peach kernels, 3g-5g of fresh ginger, 6g-9g of chrysanthemum, 6g-8g of ligusticum wallichii, 18g-20g of earthworms, 10g-12g of white medicinal powder and 15g-20g of jujubes. The raw materials supplement with one another and can be used for eliminating evils to strengthen healthy energy and matching vital energy tonifying with blood activating to keep sufficient vital energy and blood, activating the blood without damaging the healthy energy so as to achieve the effects of tonifying vital energy and activating the blood to dredge collaterals; the vital energy-benefiting brain-boosting tea has the advantages of being convenient to prepare, low in price, free from side effects and good in mouth feel.
Description
Technical field
The present invention relates to field of health-care tea, especially a kind of beneficial gas protects brain tea and preparation method thereof.
Background technology
Modern health, want healthy, essence must be ensured, gas, god, especially be gas, in good time supplementary vigour, it is the basic guarantee maintaining normal vital movement, and Traditional Chinese health tea-drinking has stronger nourishing effects to human body, especially be applicable to having a delicate constitution, immunocompromised person, secondly, the multiple antifatigue material (caffeine contained in tealeaves, theabrownin, tea polysaccharide and tea albumen), these substances reduce the decomposition of body internal protein and oxygenatedchemicals effectively, reduce the formation of serum urea nitrogen, improve the reserve capacity of hepatic glycogen and muscle glycogen, get rid of the excessive lactic acid in urine, thus improve endurance and the speed of body, and can kidney be stimulated, urine is impelled to get rid of rapidly external, that improves kidney leaches rate, reduce the time that harmful substance stops in kidney, thus contribute to human body is dispelled fatigue quickly.Conventional tea, jasmine tea, medicinal herb tea, can send a kind of quiet and beautiful fragrance after infusion, this fragrance acts on cerebral cortex by sense of smell, alleviates the various symptoms that mental fatigue causes, banishes the feeling of languor.In addition also containing various polyphenoils, body immunity and providing brain with oxygen amount can be improved, thus dizziness caused by fatigue-relieving, headache, the lazy phenomenon such as dynamic, be especially applicable to modern youth and stay up late and overtax one's nerves, operating pressure is large, the symptom that qi and blood is obstructed.
The traditional Chinese medical science is thought, gas is the rate of blood, blood being the material foundation of QI, so enrich blood and should emphasize tonifying Qi, namely so-called qi promoting blood production of mending refers to this.Gas is the power of all physiological functions of human body, is to be merged by the nature air of the vital essence of water paddy and suction.Huangdi's Internal Classics thinks that human righteousness fills Sheng, and perverse trend would not be attacked and people is caused a disease.How could tonifying Qi? tonic is a kind of important health care's method.But during tonifying Qi, should vary with each individual, the people of different physique should eat different tonifying Qi food.
Existing market has much beneficial gas protect the product of brain, but effect not obvious, and specific aim being not high, therefore, for meeting fashion and demand and the needs fast and easily of Modern human populations, needing to make further improvements existing product.
Summary of the invention
The object of the invention is to overcome the deficiency that existing market benefit gas protects brain product, provide a kind of beneficial gas to protect brain tea, have beneficial gas and mend brain, promoting blood circulation and removing blood stasis, tonifying Qi is up, effect of nourishing qi and blood.
Another object of the present invention is to provide the preparation method that above-mentioned beneficial gas protects brain tea.
For solving the problem, the present invention is achieved by the following technical solutions: a kind of beneficial gas protects brain tea, it is characterized in that: calculate by weight, formula comprises: fruit of Chinese wolfberry 8-13g, Radix Astragali 9-13g, Radix Angelicae Sinensis 14-18g, radix paeoniae rubrathe 9-14g, cassia twig 9-12g, safflower 12-15g, peach kernel 9-14g, ginger 3-5g, chrysanthemum 6-9g, Ligusticum wallichii 6-8g, earthworm 18-20g, baiyao 10-12g, date 15-20g.
Preferably, calculate by weight, formula comprises: fruit of Chinese wolfberry 12g, Radix Astragali 11g, Radix Angelicae Sinensis 15g, radix paeoniae rubrathe 12g, cassia twig 11g, safflower 14g, peach kernel 12g, ginger 4g, chrysanthemum 8g, Ligusticum wallichii 7g, earthworm 18g, baiyao 12g, date 18g.
Above-mentioned beneficial gas protects the preparation method of brain tea, it is characterized by;
(1) extract: by fruit of Chinese wolfberry 12g, Radix Astragali 11g, Radix Angelicae Sinensis 15g, radix paeoniae rubrathe 12g, cassia twig 11g, safflower 14g, peach kernel 12g, ginger 4g, chrysanthemum 8g, Ligusticum wallichii 7g, earthworm 18g, baiyao 12g, date 18g.Put into frying pan and soak 30min, decoct twice, first time decocts as 60min, retain filtrate, add 3 times of water and again decoct 40min, merging filtrate after filtering, is condensed into 1: 1, add the ethanol of 90%, limit edged stirs, and makes alcohol content reach 65%, leaves standstill and makes it precipitate, get its supernatant, heating simmer down to medicinal extract is for subsequent use.
(2) prepare softwood: add sucrose, dextrin, mixing, then add appropriate 90% ethanol, limit edged stirs, and softwood processed is for subsequent use after the oven drying 20min of 50 DEG C.
(3) whole grain: cross 20 mesh sieves, sterilization packing and get final product.
Wherein, in formula, the effect of each component is as follows:
The fruit of Chinese wolfberry: property is sweet, flat, returns liver, kidney channel.Have nourishing liver and kidney, effect of benefiting shrewd head, lose for consumptive disease essence, soreness of waist and knee joint, dizzy tinnitus, interior heat is quenched one's thirst, and the deficiency of blood is sallow, and blurred vision is not clear." Chinese Pharmacopoeia 2005 editions ", its pharmacological action has: 1, Blood pressure regulation, and fruit water-soluble extractive 20mg/kg intravenous injection can make anesthetized rabbit blood pressure reduce, respiratory stimulant; Injecting atropine cuts off both sides vagus nerve can eliminate its hypotensive effect; Be inhibitory action to extrasomatic rabbit heart, and make rabbit ear vessel retraction, methyl alcohol, acetone and other organic solvent extract also have slight hypotensive effect.2, antifatigue effect, fruit of Chinese wolfberry decoction is on the impact of mouse hydroxyproline content and resist oxygen lack and antifatigue effect: hydroxyproline (Hydroxyproline) is the seed amino acid in collagenous fibres and protein, is proline hydroxylation.Human body, in aging course, because oxygen is under-supply, affects the dihydroxylation process of proline, and thus cause hydroxyproline content in the collagen of the elderly low, main organs reduces distortion, weight saving.Because PFT is influenced, lung capacity declines, and reserve capabillity reduces, and resistance goes down, and muscular strength declines, and resist oxygen lack, anti-fatigue ability decline.Therefore hydroxyproline content is relevant with aging.Fruit of Chinese wolfberry decoction (13.23% concentration) gives mouse stomach 0.3ml/20g, every day 1 time, after 30 days Hydroxyproline concentration with compare increment rate and reach 15.49%.Fruit of Chinese wolfberry decoction gives its hypoxia-bearing capability of mouse peritoneal injection 0.3ml/20g compared with control group life span 27.9 ± 1.3 minutes, and matrimony vine is 37.5 ± 2.5 minutes (P < 0.01).Antifatigue experimental and control more also has the difference (P < 0.01) of highly significant.3, on the impact of immunologic function, have and strengthen nospecific immunity effect, mouse gavaging fruit of Chinese wolfberry water extract or intramuscular injection alcohol extract and LBP-X, be improved the phagocytic function of macrophage, strengthen the effect of serum lysozyme, improve tiring of anti-sheep red blood cell (SRBC) antibody in serum, the quantity of the antibody forming cell of anti-sheep red blood cell (SRBC) in mouse spleen can also be increased.4, delaying senility function, fructus lycii extracted solution 0.5mg/kg mouse stomach, can obviously suppress liver LPo to generate totally on the 20th, and blood two-story valley peptide peroxidase (GSH-Px) vigor and erythrocyte superoxide dismutase (SOD) vigor are improved; Human trial display can obviously suppress serum LPo to generate, and GSH-Px vigor in blood is increased, but erythrocyte sod vigor has no rising, and prompting fructus lycii extracted solution has delaying senility function, takes lycium barbarum in the present invention.
The Radix Astragali: property is sweet, warm, returns lung, the spleen channel, has invigorating qi for strengthening superficies, diuresis holder poison, apocenosis, effect of expelling pus and promoting granulation, weak for the deficiency of vital energy, anorexia and loose stool, the sinking of qi of middle-jiao, rushes down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer difficulty is burst, and burst for a long time and do not hold back, flaccidity of limbs due to deficiency of blood is yellow, and interior heat is quenched one's thirst; Chronic rephrilis protinuria, diabetes etc. " Chinese Pharmacopoeia 2005 editions ", it is the formula commonly used simply.Its main pharmacological is " invigorating qi for consolidating superficies ", can " Li Shui ", also can " promoting pus discharge and tissue regeneration " its pharmacological action have: 1, can strengthen normal heart and shrink, have cardiotonic to the heart of exhaustion.2, bacteriostatic test: this product all has inhibitory action to Shigella shigae, bacillus anthracis, α-hemolytic streptococcus, beta hemolytic streptococcus, corynebacterium diphtheriae, bacillus pseudodiphthericus, Diplococcus pneumopniae, staphylococcus aureus, Staphylococcus citreus, hay bacillus etc. in vitro, takes astragalus mongolicus in the present invention.
Radix Angelicae Sinensis: property is sweet, pungent, warm, returns liver, the heart, the spleen channel, and having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, and the effect relaxed bowel is sallow for the deficiency of blood, dizzy palpitaition, irregular menstruation, through closing dysmenorrhoea, and asthenia cold abdominalgia, the dry constipation of intestines, arthralgia due to wind-dampness, injury from falling down, ulcer sores.Prepared RADIX ANGELICAE SINENSIS with yellow rice wine activating blood to promote menstruation, through closing dysmenorrhoea, arthralgia due to wind-dampness, injury from falling down etc. " Chinese Pharmacopoeia 2005 editions ", its pharmacological action has: 1, antiasthmatic effect, and the traditional Chinese medical science is thought, Radix Angelicae Sinensis cures mainly cough with dyspnea.Now prove, Radix Angelicae Sinensis components-n-butenes husband's lactone and Ligustilide have relexation to tracheal smooth muscle; And the bronchial astehma that can cause antihistamine-acetylcholine.2, to the effect of metabolism, prove by advanced technologies such as countercurrent immunoelectrophoresis, tagging and Electronic Speculum, Radix Angelicae Sinensis can make the liver cell of in vitro culture, and protein synthesis increases, and has facilitation to the synthesis of DNA, RNA.Clinical confirmation, Radix Angelicae Sinensis can make patient's thymol turbidity reduce.Radix Angelicae Sinensis diet mouse, hepatic tissue endogenous is breathed and is strengthened, and the ability of oxidation glutamic acid significantly improves.There is protective effect to hepatic lesion caused by carbon tetrachloride, and can prevent liver glycogen from reducing.Experiment and clinically all to prove, Radix Angelicae Sinensis has effect for reducing blood fat to hyperlipidemia, and its effect is similar with medicines such as clofibrates.2.3-diphosphonic acid in animal and human's isolated cells is generated and has facilitation, reduce the affinity of hemoglobin and oxygen, promote that band oxygen hemoglobin discharges oxygen in the tissue, thus add the function of erythrocyte transport oxygen.3, the effect of anti-oxidant and scavenging free radicals, Radix Angelicae Sinensis to cerebral anoxia, postischemic reperfusion cerebrum lipid peroxide increases obvious inhibitory action.Contained forulic acid has directly minimizing H2O2 content, and is combined with membrane phospholipid acyl monoethanolamine, by directly eliminating free radical, suppressing the infringement of the antagonism such as oxidation reaction and radical reaction radical pair tissue, taking Radix Angelicae Sinensis top in the present invention.
The radix paeoniae rubrathe: property is bitter, be slightly cold, return Liver Channel, have clearing heat and cooling blood, effect of blood stasis removing analgesic, for febrile virulent maculae.Hematemesis and epistaxis, hot eyes tumour, liver-depressed hypochondrium pain, through closing dysmenorrhoea ， Disorder lump in the abdomen stomachache, injury from falling down.Carbuncle swells " Chinese Pharmacopoeias 2005 editions " such as sores, its pharmacological action has: 1, reducing blood lipid and anti arteriosclerosis effect radix paeoniae rubrathe medicinal extract sheet 5g (crude drug)/kg, take 1 every day, be used in conjunction 10-15 week, make the total plasma cholesterol (Tch) of hyperlipemia rabbit, triacylglycerol (TG), LDL-C (LDL-Ch), C-VLDL (VLDL-Ch) significantly reduce; HDL-C (HDL-Ch) and HDL2-Ch are significantly higher than control group; Tch/HDL-Ch, Tch/HDL2-Ch, LDL-Ch/HDL-Ch and LDL-Ch/HDL2-Ch ratio significantly reduces, and makes thromboxane A2/prostacyclin (TXA2/PGI2) ratio caused by hyperlipidemia be tending towards normal simultaneously.In addition also plasma lipid peroxide (LPO) can be reduced, arterial wall lipid, calcium and phosphatide and Aortic Plaque area.The mechanism of radix paeoniae rubrathe anti arteriosclerosis with improve lipoprotein component ratio, reduce plasma lipid peroxide, reduce doped calcium in arterial wall, Antiaggregating activity on platelet, regulates TXA2/PGI2 balance and activated adenyl cyclase and to increase in arterial wall cAMP concentration etc. relevant.2, the derivative n-propyl gallate of other effect radix paeoniae rubrathe composition gallic acids has the ability of scavenging activated oxygen; the mitochondrial swelling that can obviously suppress ferrous sulfate and vitamin C etc. to be induced and peroxidatic reaction of lipid, can protective wire mitochondrial structure and function normal.The radix paeoniae rubrathe without obvious effect, but can remove enterospasm caused by acetylcholine to normal isolated guinea pig ileum.Radix paeoniae rubrathe n-butanol extract 3g/kg hypodermic injection can promote the phagocytic function of reticuloendothelial system, increases liver weight, has no significant effect Hemolysin formation and delayed allergy.River red paeonia extract has remarkable inhibitory action to beta-hydroxy-Beta-methyl glutaric acid coacetylase and calcium ion channel blocker acceptor.The radix paeoniae rubrathe has comparatively high inhibition effect to shigella dysenteriae, typhoid bacillus and hemolytic streptococcus in vitro.Grass Chinese herbaceous peony decoction gavage, Rabbits ' Blood Sugar can be made temporarily to raise, and Paeonia anomala water-ol extract has significantly calm and certain analgesic activity, can also improve the acidity of gastric juice, improve a poor appetite and digestive function.Chinese herbaceous peony top is taken in the present invention.
Cassia twig: property is pungent, sweet, temperature, the thoughts of returning home, lung, urinary bladder channel, there is sweating expelling pathogenic factors from muscles and skin, warming meridian, help yang transforming qi, effect of the flat gas that spins, for anemofrigid cold, coldness and pain in the epigastrium, blood is cold through closing, joint pain, phlegm and retained fluid, oedema, palpitaition, to " Chinese Pharmacopoeias 2005 editions " such as globefish, its pharmacological action has: 1, to the effect of central nervous system, a, sedation: cinnaldehydrum 250 ~ 500mg/kg gavage has obvious sedation to mouse, show as spontaneous activity to reduce, what antagonism methyl propylamine produced crosses multi-activity, the anesthesia duration etc. of the ataxia that rotating stick test produces and prolongation ciclobarbital soluble, b, analgesic activity: experiment shows: cassia twig analgesic activity is more weak, mouse mouse tail pressurization stimulus method shows: cinnaldehydrum is without obvious analgesic activity, but to writhing response caused by lumbar injection acetic acid, then there is slight inhibitory action, the alcohol extract of cassia twig and water extract have inhibitory action, to little mousetrap tail and the pain caused unrestraint effect of boiling hot tail to the reaction of mouse acetic acid twisting, c, refrigeration function: cassia twig decoction, cinnamic acid or sodium cinnamate, to mouse normal body temperature and with the rabbit that generates heat caused by typhoid fever, paratyphoid vaccine, all there are cooling, refrigeration function, Chinese ephedra joins cassia twig has excitation to rat paw portion sweat gland secretion, therefore, numb osmanthus decoction perspiration is relevant with maincenter, d, anticonvulsant action: cinnaldehydrum 500mg/kg injects to mouse peritoneal, can delay tetanic convulsion that strychnine causes and death time, and can reduce the incidence of tetanic convulsion that nicotine causes and death, the convulsions that pentetrazole causes is then invalid.2, antivirus action: with the primary adhesion tissue cultures of human embryo kidney (HEK), cassia twig decoction (1: 20) has inhibitory action to the section 68-1 strain of A type capital, influenza Asia and orphan virus (ECHO11).On chicken embryo, infected by influenza has inhibitory action, better with 70% alcohol preserved material effect.Cassia twig spray is taken in the present invention.
Safflower: property is pungent, warm, the thoughts of returning home, Liver Channel, have activating blood to promote menstruation, effect of blood stasis removing analgesic, for through closing, dysmenorrhoea, lochia ， Disorder lump in the abdomen lump in the abdomen, injury from falling down, sore to swell and ache etc. " Chinese Pharmacopoeia 2005 editions ", comes from " Bencao Tujing ": " red indigo plant flower, namely safflower also.The present has it everywhere.Other planted by ground threshing, and winter and cloth are in cultivated land, and to spring raw seedling, Xia Naiyou flower, the lower Qiu that does converges, thorniness, and pistil goes out in strain, and people from garden holds dew and adopt it, adopts to appear again, to stopping to the greatest extent.Solid in Qiu, white, as red bean is large.It spends suddenly and violently dry very red with dye, and makes swallow fat.After main product, blood disease is victory, in fact also same, and leaf quite like blue, therefore has blue name." " hook unit stated by book on Chinese herbal medicine ": " red indigo plant flower, nourish blood decocting, and broken blood wine boils."; its pharmacological action has: 1, safflower is on the impact of the encephaledema that animal used as test cerebral arterial thrombosis causes: application Sofflower injection (1ml includes crude drug 1g); carry out preoperative 30 minutes ip to 63 mongolian gerbils and award 10g/kg Sofflower injection; and set up operative control group and sham-operation group; and observe safflower to the impact of ischemic brain edema, and have studied the change of the Monoamine in same brain district.Result prompting safflower alleviates the mechanism of ischemic brain edema, and to affect the metabolic disorder of monoaminergic transmitters in tissue relevant with it.And confirm that safflower can reduce incidence of stroke and the death rate really further, to the brain tissue of experimental chest infraction animal, there is protective effect.2, antifatigue effect: carthamin yellow 1100mg/kg mouse is compared with control group (with normal saline), and swimming time obviously extends, and rate elongation reaches 117.0%, P < 0.01.3, immunocompetence: safflower polysaccharide is different from the polysaccharide that in higher plant, a-key connects, and is similar to the polysaccharide of bacterial origin.Turn experiment from external pouring to show, safflower polysaccharide and the former ConA of T cell mitogenesis have synergy, have no significant effect the former Dex-TCMLIBansulfate of B cell mitogenesis.But PFC test in body, safflower polysaccharide is consistent with it is generally acknowledged the astragalus polyose effect trend acting on B cell.Different to the time of injected in mice safflower polysaccharide, the change of mouse PFC value is also different: after sensitization, the PFC of administration group is promoted, and before sensitization, the PFC of administration group is anti-suppressed.Show that safflower polysaccharide shows the amphicheirality of immune drug equally.Safflower polysaccharide obviously can resist the immunosuppressive action of prednisolone, and it suppresses the immunological enhancement of mouse comparatively more obvious to the effect of normal mouse to prednisolone.Therefore, safflower polysaccharide can promote to drench cell transformation, increases splenocyte to the cell number of sheep red blood cell plaque test, the immunosuppressive action etc. of antagonism prednisolone, show it be a kind of newly, be worth the immunomodulator of further research.Another Safflor yellow (SY) reduces serum lysozyme content, peritoneal macrophage and whole blood phagocytic activity of leukocytes; PFC, SRFC and antibody are produced reduce; Suppress the Ts cell activation of DH reaction and SOI induction, external, the generation of the T that SY0.03-3.0,0.1-2.0 and 0.1-2.5mg/ml suppress TdR to mix, bone-marrow-derived lymphocyte conversion, MLC reaction, IL2 and activity thereof.4. pair neural effect: ip in mice carthamin yellow 0.55g/kg, 1.1g/kg, to the mouse of injection yellow Jackets sub-threshold dose 0.3g/kg or chloraldurate sub-threshold dose 0.25g/kg, all can improve sleep rate (P < 0.01, P < 0.001), explanation obviously can strengthen the central inhibitory action of yellow Jackets and chloraldurate, and its action intensity becomes parallel relation with consumption.1.1g/kg carthamin yellow, to ip in mice, obviously can reduce mice convulsion reactivity and the death rate (P < 0.05) that nikethamidum causes, but can not resist pentylenetetrazol, caffeine and nitric acid one convulsions that causes of leaf alkali and death.Sofflower injection 10g/kg, to Mongolian sarsaparilla mouse ip, can reduce the incidence of stroke of side left neck artery ligation, obviously alleviate the encephaledema caused by cerebral apoplexy, safflower reduction stroke incidence is described and alleviates encephaledema have certain relation.Because safflower can make a cyclic extention, increase the CBF of Cerebral Region, thus alleviate encephaledema.Safflower can alleviate again the metabolic disorder of monoaminergic transmitters in brain tissue, makes the neurotransmitter of decline recover normal or close normal.This is also one of safflower mechanism alleviating encephaledema, takes extra dry red wine flower in the present invention.
Peach kernel: property is bitter, sweet, flat, the thoughts of returning home, liver, large intestine channel, have promoting blood circulation, the effect relaxed bowel, for through closing, dysmenorrhoea.Disorder lump in the abdomen lump in the abdomen, injury from falling down, the dry constipation of intestines etc. " Chinese Pharmacopoeia 2005 editions ", its pharmacological action has: peach kernel extract obviously can increase cerebral blood flow (CBF), increases the CBF of dog femoral artery, reduces vascular resistence, improves hemodynamic situation.Extract can improve the liver surface microcirculation of animal, and promotes choleresis.Peach kernel can make the hemorrhage of mouse and clotting time obviously extend, and decoction has inhibitory action to external thrombus, and decocting liquid has fiber facilitation.Containing the fat oil Castor Oil enteron aisle of 45% in peach kernel, be beneficial to defecation.Stir-baked SEMEN PERSICAE is taken in the present invention.
Ginger: property is pungent, tepor, return lung, spleen, stomach warp, there is loose trembling with fear of inducing sweat, warming middle energizer to arrest vomiting, effect of preventing phlegm from forming and stopping coughing, for anemofrigid cold, gastrofrigid vomiting, cold productive cough to cough etc. " Chinese Pharmacopoeia 2005 editions ", its pharmacological action has: 1, to the effect of the circulatory system and respiratory system, shogaol extract has excitation to anesthetized cat vasomotor center and respiratory center, also direct excitation is had to heart, normal person's chewing ginger 1g (not swallowing), systolic pressure can be made on average to raise 1.489kPa (11.2mmHg), diastolic pressure rising 1.862kPa (14mmHg), pulse frequency is then had no significant effect.2, to the effect of central nervous system, ginger has inhibitory action to central nervous system, and oil of ginger obviously can suppress spontaneous activity in mice, extends yellow Jackets lengths of one's sleep, and antagonism pentylenetetrazol is fainted from fear, analgesia, and can reduce yeast pyrogenicity rat temperature.Be the above level of spinal cord to the site of action of nervous centralis, its mechanism may have certain to contact with suppressing the easyization process of excitatory synaptic.Oil of ginger 0.4ml/kg is to rat oral gavage, and have remarkable inhibitory action to egg white foot is swollen, effect maintenance 5 hours, intensity is similar to aspirin 300mg/kg; 0.25ml/kg, to rat oral gavage, significantly can suppress granuloma induced by implantation of cotton pellets, and make atrophy of thymus gland, and adrenal gland weight increases, and points out its antiinflammatory action may be relevant with excited Pituitary Adrenalcortical system.Oil of ginger 0.25 ~ 0.4ml/kg gavage, capillary permeability caused by the swelling of paraxylene induced mice auricle, histamine or acetic acid strengthens remarkable inhibitory action.Mouse peritoneal injection fresh ginger parenteral solution 5g/kg or 10g/kg, has obvious analgesic activity.3, antioxidation, research shows: ginger Wheat Protein.In lard, add 5% ~ 10% ginger splices boil 1 ~ 4 hour, pork can be prevented corrupt; Boil the fat meat of 4 hours by this method, its peroxide number (POV) is similar to fresh lard with thiobarbital acid number (TBA); Add the lard that 20% or 50% ginger boils 4 hours, place 90 at the temperature of 30 DEG C, itself POV and TBA has almost no change.The water of ginger, ethanol and
etherextract also has remarkable inhibitory action to the oxidation of linoleic acid potassium ester.Still there is report to point out, add active oxygen scavenger or ginger extract, the DNA damage that energy anti-lipid peroxidation causes; Ginger extract also can the generation of inhibit activities oxygen and linoleic oxidation.Ginger rhizome is taken in the present invention.
Chrysanthemum: property is sweet, bitter, be slightly cold, return lung, Liver Channel, have loose wind heat-clearing, effect of flat liver improving eyesight, for anemopyretic cold, have a headache dizzy, red eye, swell pain, the dim-sighted grade of eyes " Chinese Pharmacopoeia 2005 editions ", its pharmacological action has: 1, the phenol position of cardiovascular aspect pharmacological action chrysanthemum can increase guinea pig isolated heart coronary flow, improve mouse to the tolerance of hypobaric hypoxia, and to the heart of rabbit, Liver and kidney function without overt toxicity effect.The total extract of chrysanthemum all shows isolated heart, cardiac muscle cell and has positive inotropic action, and FLOS CHRYSANTHEMI ALBA from Haizhou of China has the rat ventricular of anti-Aconitine Induced, and the mouse Arrhythmia that chloroform brings out.2, anti-aging effects chrysanthemum can strengthen glutathione peroxidating reduction, obviously extends the silkworm life-span; Mouse heart and brain resisting oxygen lack can also be improved; extend the ability of its life span and scavenging free radicals; someone studies, and finds; chrysanthemum extract has obvious protective effect to the damage of biomembranous ultra-oxygen anion free radical, mainly shields by after the glyceride that directly enters cell membrane.This new discovery makes chrysanthemum be expected to develop and become new functional food, in antisenility cistanche food, especially play its effect.Hang Ju is taken in the present invention.
Ligusticum wallichii: property is pungent, warm, returns liver, courage, pericardium channel, has blood-activating and qi-promoting, effect of wind-expelling pain-stopping, for irregular menstruation, through closing dysmenorrhoea ， Disorder lump in the abdomen stomachache, and the shouting pain of the chest side of body, tumbling and swelling, headache.Arthralgia due to wind-dampness etc. " Chinese Pharmacopoeia 2005 editions ", its pharmacological action has: 1, to the effect of central nervous system, and Ligusticum wallichii has obvious sedation.Inhibited to the activity of animal brain when rhizoma chuanxiong volatile oil is a small amount of, and to medulla oblongata respiratory center, vasomotor center and spinal reflex maincenter, there is excitation.Ligusticum wallichii decoction all can suppress its spontaneous activity to respectively large and small mouse ig, and the mouse sleep time that yellow Jackets are caused extends, and can resist the excitation of caffeine (20mg/kg).But the rat can not resisted caused by pentylenetetrazol is fainted from fear.By Ligusticum wallichii decoction 25-50g/kg gavage, can suppress the spontaneous activity of rat, to the calmness of mouse, comparatively rat is more obvious; It can also extend the length of one's sleep of amobarbital, but can not the excitement of antagonism caffeine, can not prevent convulsions or the lethal effect of leptazol, cocaine.It is inhibited that Japan produces the activity of volatile oil part to animal brain of Ligusticum wallichii, and have excitation to the vasomotor center respiratory center of medulla oblongata and spinal reflex, and dosage strengthens, then all transfer suppression to.2, anti-radiation function, Ligusticum wallichii decoction has certain curative effect to animal radiation sickness experimental therapy.The water-soluble crude preparation of Ligusticum wallichii damages the radiation exposure of rat, mouse and dog and mustargen all has protective effect.Anti-the penetrate effect of Ligusticum wallichii to rat is better than mouse, and ip is better than im administering effect, and im administration is effective compared with ig.Rhizome of Ligusticum Sinense Oliv. Cv. Chuanxiong is taken in the present invention.
Earthworm: property is salty, cold, returns liver, spleen, urinary bladder channel, have heat-clearing arresting convulsion, dredging collateral, relievings asthma, effect of diuresis, for unconsciousness due to high fever, frightened sick tic, joint pain, extremity numbness, hemiplegia.Dyspnea and cough due to lung-heat, oliguria oedema; Hypertension etc. " Chinese Pharmacopoeia 2005 editions ", its pharmacological action has; 1, to neural effect, treatment cerebral arterial thrombosis (apoplexy): lumbar injection earthworm injection 10g/kg in advance, the pre-always cerebral arterial thrombosis that artery ligation causes is surveyed to mongolian gerbils one there is certain prevention effect, the symptom of cerebral arterial thrombosis can be alleviated, incidence as piloerection, turn-take behavior and outbreak etc. of rolling about declines, and obviously reduce the death rate of animal, make monoamine transmitters 5 one hydroxytryptamine that reduces in cerebral arterial thrombosis animal brain and dopamine be tending towards recovering, Noradrenaline Contents is then had no significant effect.Anticonvulsion and sedation: the extract of mouse peritoneal injection earthworm lead acetate process, obviously can resist the convulsions that pentylenetetrazol and caffeine cause, but the convulsions rather caused of soil can not be resisted, point out its anticonvulsant action position to be nervous centralis position more than spinal cord.Mouse peritoneal injection earthworm alcohol leaching liquid 20g/kg, also have antagonism to electrofit, ED is 22.18g/kg.The immersion liquid of earthworm alcohol has sedation to mouse, rabbit.Refrigeration function: earthworm water logging agent all has good refrigeration function to the heating rabbit that escherichia coli endotoxin and warm stimulation cause, but weak compared with the effect of aminopyrine.Oral LUMBRICUS falls apart 12g, to Healthy People body temperature without reducing effect, aspirin (oral 0.3g) is better than to fever caused by infection patient cooling effect also effective to noninfectious fever, but effect occurs more late, generally effective in the about rear 0.5-3h of clothes, 2-5h body temperature is down to normally.Dry earthworm is taken in the present invention.
Baiyao; There is wines used as antirheumatic; Effect of pain relieving, for arthralgia due to wind-dampness; Injuries from falls as well heat-clearing dissolving phlegm, removing pattogenic heat from the blood and toxic material from the body, pain relieving.Cure mainly and control pharyngalgia larynx numbness, cough, haematemesis, bleeding from five sense organs or subcutaneous tissue, gold creates blood, and hot malicious carbuncle swells, scrofula, and its drug action has: " Illustrated Book on Plants ": " suffer from dentalgia person, Qie Qigen pastes on gum, energy tonifying kidney and nourishing yin of holding concurrently "." Chinese herbal medicine handbook is commonly used in Hunan Rural Areas ": " removing toxic substances of dispeling the wind, clearing and activating the channels and collaterals "." property of medicine opinion ": " control plug heat in larynx, numbness of choking is obstructed, in the heart mountain pass plug, normal pain in pharynx, swelling ".Baiyao root is taken in the present invention.
Date: property is sweet, warm, return spleen, stomach warp, there is tonifying middle-Jiao and Qi, effect of nourishing blood and tranquilization, few for board void food, weak loose stool, hysteria of womam etc. " Chinese Pharmacopoeia 2005 editions ", red date has the effects such as qi-restoratives benefit gas, nourishing blood and tranquilization, strengthening the spleen and stomach, and red date has good therapeutic effect to illnesss such as chronic hepatitis, cirrhosis, anaemia, anaphylactoid purpuras; Red date contains triterpene compound and CAMP, has stronger anticancer, anti-allergic effects.Date can moisten cardiopulmonary, cough-relieving, tonifying five zang organs, it is deficient to control, except stomach addiction gas, support spleen, flat stomach Qi, logical nine orifices in can also pacifying, help 12 through etc., its pharmacological action has: 1, immunosuppressive action, the alcohol extract of date with every day 100mg to rat oral gavage, display date has same immunosuppressive action with imuran, can suppress the generation of antibody to atopic diseases.Date alcohol extract may have inhibitory action to rat reactive antibody, and does not produce inhibitory action to non-reacted antibody.2, sleep is promoted, pharmacological research finds, containing various bioactivators in date, plurality kinds of health care is had to cure the disease effect to human body, date has effect such as qi-restoratives benefit gas, nourishing blood and tranquilization, strengthening the spleen and stomach etc., is the good health nutrient of the patients such as weakness of the spleen and the stomach, insufficiency of vital energy and blood, lassitude, insomnia and dreamful sleep.Date is taken for slight good supplemental treatment of can yet be regarded as of having a sleepless night from clinical practice.As ineffective, stable control suitably can be used, but can not long-term taking.Long-term taking is stable has comparatively major injury to health, and as patient produces drug dependence, and employing is filled a prescription, treatment, as formula etc., has curative effect comparatively significantly in stable use of should as far as possible cutting down according to the circumstance.In addition, insomniac should cultivate good habits and customs, and take a walk as after supper more, usually do more physical exercises etc., these recoveries for sleep all have good help.
The beneficial gas of one of the present invention protects brain tea, and it fills a prescription with the Radix Astragali for main side, the vigour of large tonifying spleen and stomach, and make the prosperous blood of gas, the stasis of blood removes ruton; Radix Angelicae Sinensis, red date is invigorated blood circulation to be longer than, and doublely can nourish blood, stagnation resolvation and non-blood trouble wonderful, is aided with the radix paeoniae rubrathe, Ligusticum wallichii, peach kernel, safflower, cassia twig, baiyao, ginger, helps Radix Angelicae Sinensis promoting blood circulation, warming meridian, help yang transforming qi, wines used as antirheumatic; Help with earthworm, chrysanthemum, the fruit of Chinese wolfberry, dredging collateral, heat-clearing, flat liver kidney-nourishing, coordinate with the Radix Astragali, strengthens the power of invigorating qi and dredging collateral, all row whole bodies, each prescription complements each other, eliminating pathogen to support vital qi, and tonifying Qi matches with invigorating blood circulation, the prosperous then blood of gas, invigorate blood circulation and don't just hinder, playing the merit of collaterals altogether, prescription have preparation convenient, cheap, have no side effect, advantage that mouthfeel is good.
The beneficial gas of one of the present invention protects brain tea and preparation method thereof, and its excellent feature is also:
One, all side's proportioning science, have the merit of qi and activate blood circulation dredging collateral, and its preparation is simple, easy to use, have no side effect:
Two, the tonifying Qi in formula can strengthen cellular immunity and increase antibody and be formed;
Three, promoting blood circulation and removing blood stasisly blood flow viscosity can be changed in formula;
Four, can capillary of kidney be dredged, suppress ephritis development, and can albuminuria be controlled;
Five, energy dissipating phlegm for resuscitation dredging collateral, improves local circulation, recovers blood flow and vessel wall elasticity, the limbs attached undue importance to one thing to the neglect of the other comparatively fast are recovered; ,
Six, to mend, mend slip-knot and close, have the merit of strengthening vital QI to eliminate pathogenic factors;
Seven, a large amount of tonifying Qi matches with invigorating blood circulation on a small quantity, and the prosperous then blood of gas, invigorates blood circulation and don't just hinder, and has tool with the merit of playing collaterals;
Eight, be in sticky, dense, solidifying, poly-tendency for blood samples of patients, after a procedure, the content of Cyclic Adenosine monophosphate in blood platelet can be increased, Antiaggregating activity on platelet and release reaction, suppress and thrombus, to improve microcirculation, promote offshoot circulation.
Detailed description of the invention
The present invention is achieved by the following technical solutions: a kind of beneficial gas protects brain tea, and it is characterized in that: calculate by weight, formula comprises: fruit of Chinese wolfberry 8-13g, Radix Astragali 9-13g, Radix Angelicae Sinensis 14-18g, radix paeoniae rubrathe 9-14g, cassia twig 9-12g, safflower 12-15g, peach kernel 9-14g, ginger 3-5g, chrysanthemum 6-9g, Ligusticum wallichii 6-8g, earthworm 18-20g, baiyao 10-12g, date 15-20g.
Preferably, calculate by weight, formula comprises: fruit of Chinese wolfberry 12g, Radix Astragali 11g, Radix Angelicae Sinensis 15g, radix paeoniae rubrathe 12g, cassia twig 11g, safflower 14g, peach kernel 12g, ginger 4g, chrysanthemum 8g, Ligusticum wallichii 7g.Earthworm 18g, baiyao 12g, date 18g.
The beneficial gas of one of the present invention protects brain tea, and its preparation method is:
(1) extract: by fruit of Chinese wolfberry 12g, Radix Astragali 11g, Radix Angelicae Sinensis 15g, radix paeoniae rubrathe 12g, cassia twig 11g, safflower 14g, peach kernel 12g, ginger 4g, chrysanthemum 8g, Ligusticum wallichii 7g, earthworm 18g, baiyao 12g, date 18g.Put into frying pan and soak 30min, decoct twice, first time decocts as 60min, retain filtrate, add 3 times of water and again decoct 40min, merging filtrate after filtering, is condensed into 1: 1, add the ethanol of 90%, limit edged stirs, and makes alcohol content reach 65%, leaves standstill and makes it precipitate, get its supernatant, heating simmer down to medicinal extract is for subsequent use.
(2) prepare softwood: add sucrose, dextrin, mixing, then add appropriate 90% ethanol, limit edged stirs, and softwood processed is for subsequent use after the oven drying 20min of 50 DEG C.
(3) whole grain: cross 20 mesh sieves, sterilization packing and get final product.
Embodiment 1
By fruit of Chinese wolfberry 12g, Radix Astragali 11g, Radix Angelicae Sinensis 15g, radix paeoniae rubrathe 12g, cassia twig 11g, safflower 14g, peach kernel 12g, ginger 4g, chrysanthemum 8g, Ligusticum wallichii 7g, earthworm 18g, baiyao 12g, date 18g.Put into frying pan and soak 30min, decoct twice, first time decocts as 60min, retains filtrate, add 3 times of water and again decoct 40min, merging filtrate after filtering, is condensed into 1: 1, adds the ethanol of 90%, limit edged stirs, and makes alcohol content reach 65%, leaves standstill and makes it precipitate, get its supernatant, heating simmer down to medicinal extract is for subsequent use, adds sucrose, dextrin, mixing, add appropriate 90% ethanol again, limit edged stirs, softwood processed, for subsequent use after the oven drying 20min of 50 DEG C, cross 20 mesh sieves, sterilization packing and get final product.
Embodiment 2
By fruit of Chinese wolfberry 11g, Radix Astragali 12g, Radix Angelicae Sinensis 16g, radix paeoniae rubrathe 13g, cassia twig 10g, safflower 13g, peach kernel 11g, ginger 5g, chrysanthemum 9g, Ligusticum wallichii 8g, earthworm 18g, baiyao 11g, date 19g.Put into frying pan and soak 30min, decoct twice, first time decocts as 60min, retains filtrate, add 3 times of water and again decoct 40min, merging filtrate after filtering, is condensed into 1: 1, adds the ethanol of 90%, limit edged stirs, and makes alcohol content reach 65%, leaves standstill and makes it precipitate, get its supernatant, heating simmer down to medicinal extract is for subsequent use, adds sucrose, dextrin, mixing, add appropriate 90% ethanol again, limit edged stirs, softwood processed, for subsequent use after the oven drying 20min of 50 DEG C, cross 20 mesh sieves, sterilization packing and get final product.
The beneficial gas of one of the present invention protects brain tea to blood-enrich, and metabolic promotion has obvious curative effects.It is below partial clinical example.
Clinical example 1
Ancient certain, man, 35 years old, patient was because of after cerebral thrombus is in hospital and rescues, and right side quadriplegia need not.Dysphasia, discomfort uncomfortable in chest, sound of the sputum in the throat, companion's painful swelling of joints, there is purple plague purpura on thin and greasy fur limit, wiry and rolling pulse.This is that the deficiency of vital energy can not run blood, and phlegm stasis blocking, in train of thought, belongs to apoplexy sequela, then adopts embodiment 2 product, closes reducing phlegm by resuscitation.Every day 2 times, brew 300 milliliters, after taking 1 month continuously, complexion is clearly better at every turn, dizzy transference cure, and lower limb are restore funcitons, in person can walk to treat-and-release.Though upper limbs can be movable, hold thing and still owe freely, speech is also normal.
Clinical example 2
Lee, man, 55 years old, patient was dizzy repeatedly difficult because of cervical spondylopathy retrogression pathological changes.See dizzy as sat journey time medical, upper limbs fiber crops pain, time have insomnia, god is tired, feel sick, raw phlegm, tongue fur featheredge has the stasis of blood purple, qi deficiency to blood stasis and train of thought is obstructed, lucid yang failing to raise, adopts embodiment one product then, the all dirty gas of benefit, the blood of the whole body of living, to improve local blood circulation, promote neurological functional recovery, patient every day 2 times, brew 300 milliliters at every turn, after taking 20 days continuously, cervical vertebra moving is freely, no longer dizzy.
Clinical example 3
Week certain, female, 29 years old, patient engaged in educational work, and whenever teaching frequent and hoarseness, had no effective through multi-treatment.Heavy time light during hoarseness, dry throat, vertigo, body acid, occasionally have raw phlegm, menses is uncomfortable, the light few tongue of tongue, small and wiry pulse.Through city, examination in hospital is diagnosed as singer's node, and the traditional Chinese medical science is examined as qi deficiency to blood stasis, and train of thought is unfavorable, upper knot throat, controls suitable qi and activate blood circulation, stagnation resolvation relieve sore throat.Press: ferritic is weak, and sing heartily for a long time, secretly consume qi and blood, blood operation is unfavorable, train of thought blood stasis, then embodiment one product is adopted then to adopt embodiment two product, benefiting qi and removing blood stasis, activating collaterals and eliminating stagnation, patient every day 2 times, brew 300 milliliters, after taking 30 days continuously, sound recovers as before, satisfaction of producing effects at every turn.
Clinical example 4
Dragon certain, female, 60 years old.Patient has hypertension history.Numb limb when examining, trembles more than, though can stand, can not open step, and upper limbs shake causes and can not hold thing.Vertigo, god is tired, lazy speech of breathing hard, vexed, uneasy sleeping at night.The red few tongue limit of tongue is purple, small and wiry pulse.Card belongs to qi deficiency to blood stasis, the resistance of pneumatic network, and then adopt embodiment two product, Yiqi-Huoxue-Huayu shakes surely, patient every day 2 times, brews 300 milliliters at every turn, after taking 15 days continuously, trembles and subtract greatly, can stride, and it is also gradually normal that upper limbs holds thing.
Claims (3)
1. beneficial gas protects a brain tea, it is characterized in that: calculate by weight, and raw material is: fruit of Chinese wolfberry 8-13g, Radix Astragali 9-13g, Radix Angelicae Sinensis 14-18g, radix paeoniae rubrathe 9-14g, cassia twig 9-12g, safflower 12-15g, peach kernel 9-14g, ginger 3-5g, chrysanthemum 6-9g, Ligusticum wallichii 6-8g, earthworm 18-20g, stephanotis 10-12g, date 15-20g.
2. the beneficial gas of one according to claim 1 protects brain tea, it is characterized in that: calculate by weight, and raw material is: fruit of Chinese wolfberry 12g, Radix Astragali 11g, Radix Angelicae Sinensis 15g, radix paeoniae rubrathe 12g, cassia twig 11g, safflower 14g, peach kernel 12g, ginger 4g, chrysanthemum 8g, Ligusticum wallichii 7g, earthworm 18g, stephanotis 12g, date 18g.
3. a beneficial gas according to claim 2 protects the preparation method of brain tea, it is characterized in that: preparation method prepares each component, put into frying pan in the lump and soak 30min, decoct twice, first time decocts as 60min, retain filtrate, the dregs of a decoction add 3 times of water and again decoct 40min, merging filtrate after filtering, be condensed into 1: 1, add the ethanol of 90%, limit edged stirs, alcohol content is made to reach 65%, leaving standstill makes it precipitate, get its supernatant, heating simmer down to medicinal extract is for subsequent use, add sucrose, dextrin, mixing, add appropriate 90% ethanol again, limit edged stirs, softwood processed, for subsequent use after the oven drying 20min of 50 DEG C, cross 20 mesh sieves, sterilization packing and get final product.
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| CN1279943A (en) * | 2000-06-29 | 2001-01-17 | 赵国林 | Concentrated granule medicine of famous decoction formulation and its preparation |
| CN101658565A (en) * | 2009-08-10 | 2010-03-03 | 黄山 | Granules for benefiting qi and removing blood stasis |
| CN102430102A (en) * | 2011-12-07 | 2012-05-02 | 哈药集团中药二厂 | Preparation method for huangqi-guizhi-wuwu granule |
| CN102783688A (en) * | 2012-08-02 | 2012-11-21 | 李之国 | Beverage and preparation method thereof |
| CN103190494A (en) * | 2013-04-11 | 2013-07-10 | 渭源县莲峰镇绽坡村康荣中药材专业合作社 | Selenium-rich Astragalus root health protection tea and tea bag thereof |
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| CN1279943A (en) * | 2000-06-29 | 2001-01-17 | 赵国林 | Concentrated granule medicine of famous decoction formulation and its preparation |
| CN101658565A (en) * | 2009-08-10 | 2010-03-03 | 黄山 | Granules for benefiting qi and removing blood stasis |
| CN102430102A (en) * | 2011-12-07 | 2012-05-02 | 哈药集团中药二厂 | Preparation method for huangqi-guizhi-wuwu granule |
| CN102783688A (en) * | 2012-08-02 | 2012-11-21 | 李之国 | Beverage and preparation method thereof |
| CN103190494A (en) * | 2013-04-11 | 2013-07-10 | 渭源县莲峰镇绽坡村康荣中药材专业合作社 | Selenium-rich Astragalus root health protection tea and tea bag thereof |
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