CN102949618A - Multifunctional diet tea - Google Patents
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- CN102949618A CN102949618A CN2012100869234A CN201210086923A CN102949618A CN 102949618 A CN102949618 A CN 102949618A CN 2012100869234 A CN2012100869234 A CN 2012100869234A CN 201210086923 A CN201210086923 A CN 201210086923A CN 102949618 A CN102949618 A CN 102949618A
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Abstract
The invention relates to a multifunctional diet tea, consisting of thirty-seven traditional Chinese medicines as follows: astragalus, burdock, cassia seed, glossy privet fruit, apocynum venetum, elephant foot, lotus leaf, rhizoma polygonati, five-leaf gynostemma herb, Chinese hawthorn leaf, alfalfa, coix seed, spatholobus suberctu, summer purslane, rhizoma alismatis, caulis akebiae, divaricate saposhnikovia root, eucommia ulmoides, cortex cinnamomi, polygonum multiflorum, rosemary, beautiful sweetgum fruit, rose, centella, esliptae herba, radix bupleuri, radix scutellariae, Chinese magnoliavine fruit, hawthorn, cacumen biotae, pine needle, grape seed, oriental wormwood, acanthopanax root, parasitic loranthus, white atractylodes rhizome and felwort. The multifunctional diet tea related by the invention has obvious effects of reducing fat and losing weight, improving the metabolism of the body and curing gout and hyperlipidemia.
Description
Technical field
The present invention relates to a kind of health tea, particularly relate to a kind of multifunctional weight losing tea that can reduce metabolic arthritis value in cholesterol level, blood circulation promoting, the reduction gout take Chinese herbal medicine as raw material.
Technical background
Obesity is one of important risk factor of non-spreading venereal diseases morbidity, has become the first killer who threatens human health.At present along with the improving constantly of people's living standard, increasing people are because busy, and ignore motion; Next is that people depend on electric network and link up with the colleague owing to being electronic age now, and the discussion public affair of being disinclined to go on foot; Moreover be often to eat out too much food.For many years, the topic of relevant fat-reducing never interrupted, on January 9th, 2008 was the patent of 200510042926 " a kind of contain reducing fat lose weight the tea of fat Chinese herbal medicine " in a kind of patent No. of the Chinese patent communique of State Intellectual Property Office bulletin, it adopts Fructus Crataegi, Semen Cassiae, Folium Nelumbinis, Poria, Semen Raphani, Semen Pruni, Radix Polygoni Multiflori Preparata, Rhizoma Alismatis, Folium Ilicis, Herb Gynostemmae Pentaphylli formulated, although certain curative effect is arranged, function is not strong.
Summary of the invention
In order to overcome the deficiencies in the prior art, the present invention relates to a kind of health tea, particularly relate to a kind of multifunctional weight losing tea that can reduce metabolic arthritis value in cholesterol level, blood circulation promoting, the reduction gout take Chinese herbal medicine as raw material.
The object of the present invention is achieved like this: a kind of multifunctional weight losing tea is to be made by the crude drug of following weight proportion:
The Radix Astragali 6～7 weight portions, Fructus Arctii 3～6.4 weight portions, Semen Cassiae 3～6.4 weight portions, Fructus Ligustri Lucidi 3～6.4 weight portions, Herba Apocyni veneti 3～6.4 weight portion Rhizoma amorphophalli 3～6.4 weight portions, Folium Nelumbinis 3～6.4 weight portions, Rhizoma Polygonati 2.8～3.4 weight portions, Herb Gynostemmae Pentaphylli 2.8～3.4 weight portions, Folium Crataegi 2.8～3.4 weight portions, alfalfa 2.8～3.4 weight portions, Semen Coicis 2.8～3.4 weight portions, Caulis Spatholobi 2.8～3.4 weight portions, Herba portulacae 2.8～3.4 weight portions, Rhizoma Alismatis 2.8～3.4 weight portions, Caulis Akebiae 2.8～3.4 weight portions, Radix Saposhnikoviae 2.8～3.4 weight portions, the Cortex Eucommiae 2～2.8 weight portions, Cortex Cinnamomi 2～2.8 weight portions, Radix Polygoni Multiflori 2～2.8 weight portions, repeatedly fragrant 2～2.8 weight portions, Fructus Liquidambaris 1～2.2 weight portion, Flos Rosae Rugosae 1～2.2 weight portion, Herba Centellae 1～2.2 weight portion, Herba Ecliptae 1～2.2 weight portion, Radix Bupleuri 1～2.2 weight portion, Radix Scutellariae 1～2.2 weight portion, Fructus Schisandrae Chinensis 1～2.2 weight portion, Fructus Crataegi 1～2 weight portion, Cacumen Platycladi 1～2 weight portion, Folium Pini 1～2 weight portion, Semen Vitis viniferae 1～2 weight portion, Herba Artemisiae Scopariae 1～2 weight portion, Radix Et Caulis Acanthopanacis Senticosi 1～2 weight portion, Herba Taxilli 1～2 weight portion, the Rhizoma Atractylodis Macrocephalae 1～2 weight portion, Radix Gentianae 1～2 weight portion.
Chinese medicine composition preferred feedstock medicine weight portion of the present invention is:
The Radix Astragali 6.5 weight portions, Fructus Arctii 4.7 weight portions, Semen Cassiae 4.7 weight portions, Fructus Ligustri Lucidi 4.7 weight portions, Herba Apocyni veneti 4.7 weight portion Rhizoma amorphophalli 4.7 weight portions, Folium Nelumbinis 4.7 weight portions, Rhizoma Polygonati 3.1 weight portions, Herb Gynostemmae Pentaphylli 3.1 weight portions, Folium Crataegi 3.1 weight portions, alfalfa 3.1 weight portions, Semen Coicis 3.1 weight portions, Caulis Spatholobi 3.1 weight portions, Herba portulacae 3.1 weight portions, Rhizoma Alismatis 3.1 weight portions, Caulis Akebiae 3.1 weight portions, Radix Saposhnikoviae 3.1 weight portions, the Cortex Eucommiae 2.4 weight portions, Cortex Cinnamomi 2.4 weight portions, Radix Polygoni Multiflori 2.4 weight portions, fragrant 2.4 weight portions change, Fructus Liquidambaris 1.6 weight portions, Flos Rosae Rugosae 1.6 weight portions, Herba Centellae 1.6 weight portions, Herba Ecliptae 1.6 weight portions, Radix Bupleuri 1.6 weight portions, Radix Scutellariae 1.6 weight portions, Fructus Schisandrae Chinensis 1.6 weight portions, Fructus Crataegi 1.5 weight portions, Cacumen Platycladi 1.5 weight portions, Folium Pini 1.5 weight portions, Semen Vitis viniferae 1.5 weight portions, Herba Artemisiae Scopariae 1.5 weight portions, Radix Et Caulis Acanthopanacis Senticosi 1.5 weight portions, Herba Taxilli 1.5 weight portions, the Rhizoma Atractylodis Macrocephalae 1.5 weight portions, Radix Gentianae 1.5 weight portions.
The preparation method of pharmaceutical composition of the present invention:
With the above-mentioned raw materials medicine according to weight ratio weigh, clean, dry, pulverized sterilization behind 10～20 mesh sieves, pack, 3-8 g/bag of dress.
Usage and dosage: boiled water is taken after mixing it with water, and 1 bag/time, 3 times/days.
The present invention is according to Chinese medical theory, in line with regulate body's immunity, the enhancing cellular metabolism is purpose, take the Radix Astragali, Fructus Arctii, Semen Cassiae, Fructus Ligustri Lucidi, Radix Polygoni Multiflori as monarch drug, carry out QI invigorating, wind dispelling, reduce phlegm, dehumidify, promote gastrointestinal peristalsis, remove stool, blood fat reducing blood pressure in the body, improve blood flow; Utilize Folium Crataegi, Folium Nelumbinis, alfalfa, Rhizoma Alismatis, Fructus Crataegi, Rhizoma Polygonati, Herb Gynostemmae Pentaphylli, Semen Coicis, Caulis Spatholobi, Herba portulacae, Semen Vitis viniferae, Flos Rosae Rugosae, Herba Centellae, Herba Ecliptae, Radix Bupleuri, Radix Scutellariae, Fructus Schisandrae Chinensis, Herba Artemisiae Scopariae, Herba Taxilli, the Rhizoma Atractylodis Macrocephalae, Radix Gentianae to be ministerial drug, come anticoagulant, vessel softening, cholesterol reducing suppresses fat; Utilize Herba Artemisiae Scopariae, Cortex Cinnamomi, the Cortex Eucommiae, Radix Saposhnikoviae, Radix Et Caulis Acanthopanacis Senticosi, Cacumen Platycladi, Folium Pini to be adjuvant drug, remove interior free yl, and utilize alkalescent medicine Herba Apocyni veneti, Rhizoma amorphophalli variant liquid to be alkalescence, jointly reach eliminating damp-heat, get rid of uric acid, antibacterial, hypertension and hyperlipemia, the effect for the treatment of gout.The medicine enhancing efficacy of a drug is walked to alter, blood circulation promoting in order to make for Caulis Akebiae, the perfume that changes, Fructus Liquidambaris.
The crude drug that the present invention adopts is:
The Radix Astragali:
Have another name called Radix Astragali, have the body's immunity of adjusting, strengthen cellular metabolism, heart tonifying blood pressure lowering, improve blood flow and the anti-ageing effect of waiting for a long time.
Fructus Arctii:
Another name Fructus Arctii, Fructus Arctii, evil reality, FRUCTUS ARCTII etc. have dispelling wind and heat pathogens, removing summer-heat pyretic toxicity, subduing swelling and detoxicating effect.
Semen Cassiae:
Have loosening bowel to relieve constipation, blood fat reducing makes eye bright, the energy liver heat removing and eyesight improving, and the diuretic relieving constipation has laxative action, reducing blood pressure and blood fat.
Fructus Ligustri Lucidi:
Have another name called Fructus Ligustri Lucidi reality, Fructus Ilicis Purpureae etc., have nourishing the liver and kidney, the effect of the black hair that makes eye bright.
Herba Apocyni veneti:
Have another name called ambary, wild flax, bluish dogbane etc., can relieve inflammation or internal heat, the effect of blood pressure lowering, heart tonifying, diuresis.
Rhizoma amorphophalli:
Be Rhizoma amorphophalli, another name water dog son, Tacca chantrieri Andre, Radix et Rhizoma Rhei Franzenbachii, large Rhizoma Schizocapsae Plantagineae, cattle gallbladder etc., energy heat-clearing and toxic substances removing; Regulating QI to relieve pain.
Folium Nelumbinis:
Another name is given birth to Folium Nelumbinis, dry Folium Nelumbinis etc., has clearing away summer-heat, sending up the lucid YANG, cooling blood for hemostasis
Rhizoma Polygonati:
Another name polygonatum sibiricum Redoute, Caput Gallus domesticus root, yellow chicken dish, spleen reinforcing can the lung moistening and production of body fluid promoting.Quench one's thirst for weakness of the spleen and stomach, deficiency of the lung cough caused by dryness, interior-heat.
Herb Gynostemmae Pentaphylli:
The another name Herba Gynostemmatis, eliminating inflammation and expelling toxin, eliminating phlegm and stopping cough.
Folium Crataegi:
Be the leaf of rosaceous plant Fructus Pyri Pashiae or Crataegi cuneatae etc., the effect of blood fat reducing prevention of cardiac recurrence.
Alfalfa:
Have another name called alfalfa, Herba Medicaginis, contain the chemical compositions such as flavone, saponin, coumarin, sterol, monoterpene and organic acid, wherein flavone compound is the main composition monoid, have cholesterol reducing, prevent and treat the functions such as coronary heart disease.
Semen Coicis:
The energy promoting diuresis to eliminate damp pathogen helps clearing away heat and discharging pus and treatment rheumatism of muscles.
Caulis Spatholobi:
The another name Radix seu Caulis Verntilaginis Leiocarpae, the promoting the circulation of blood of enriching blood, soothing the channels and quicking the network vessels.
Herba portulacae:
Another name Dens Equi dish, peaceful and comfortable grass, five elements' grass, beans lobe bean grass etc.Heat-clearing and toxic substances removing, hemostasis.
Rhizoma Alismatis:
Another name watery diarrhea, Rhizoma Alismatis, swan rush down, Semen Nelumbinis and rushing down, and diuresis, effect for reducing blood fat, lipotropy, cardiac muscle are had slight inhibitory action, suppress the tulase growth, blood coagulation resisting function.
Caulis Akebiae:
The another name Fructus Akebiae, energy pathogenic fire purging row water, promoting blood circulation.
Radix Saposhnikoviae:
Another name copper rues, Hui Yun, return grass, Rhizoma Cibotii, hundred kinds, screen, wind meat etc., has expelling pathogenic wind from the body surface, removing dampness to relieve pain, and relieving convulsion is jerked surely.
The Cortex Eucommiae:
Another name wood is continuous, think of is secondary, it is celestial to think, the silk gross weight, and for lumbago due to renal deficiency, muscles and bones is unable, blood leaking in gestation, frequent fetal movement; Hypertension.
Cortex Cinnamomi:
Have another name called Cortex Cinnamomi, cylinder osmanthus, Gui Ertong, osmanthus logical, have calmness, cooling, blood pressure lowering, digestion promoting function.
Radix Polygoni Multiflori:
The another name Radix Polygoni Multiflori, Herba Stellariae Saxatilis, redly hold back, Chen Zhibai, the effect of nervus centralis is had aobvious antagonism, blood fat reducing and arteriosclerosis, can make that blood rbc number and content of hemoglobin increase, immunologic function strengthens.
Repeatedly fragrant:
Can strengthen corticocerebral process of inhibition, hypnosis, anticonvulsant action are arranged.
Fructus Liquidambaris:
Ball on another name maple reality, the maple has dispelling wind and removing obstruction in the collateral, the diuretic dehumidifying.
Flos Rosae Rugosae:
Another name Flos Rosae Multiflorae, hybrid roses, foreign Flos Rosae Rugosae, Flos Rosae Davuricae, the flower of pacing up and down, promoting QI circulation for relieving depression, promoting blood circulation and stopping pain.
Herba Centellae:
There is calm stable effect another name Herba Glechomae, marchantia grass, Herba Calthae Membranaceae, Gotu Kola, certain herbaceous plants with big flowers Penglai to nervus centralis, can treat skin ulcer.
Herba Ecliptae:
Cry again " Herba Ecliptae ", different name is again Nanjing grass, Alternanthera sessilis (L.) DC., has liver and kidney tonifying, tonifying YIN black hair, health care, cooling blood for hemostasis.
Radix Bupleuri:
Another name ground is smoked, eggplant grass, HERBA BUPLEURI, RADIX BUPLEURI SCORZONERIFOLII, deceive Radix Bupleuri, energy reconciling superficies and interior, soothing the liver, yang invigorating.
Radix Scutellariae:
Another name bar a kind of reed mentioned in ancient books, gold bar, scarf grass, Boehmeria longispica Steud. are sub, mountain dish root, gold bar root, perfume pasture and water.Heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.
Fructus Schisandrae Chinensis:
Has convergence astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.
Fructus Crataegi:
Help digestion long-pending dissipating blood stasis blood, expelling tenia.Control that meat is long-pending, promoting digestion and invigorating the stomach, the circulation of qi promoting dissipating blood stasis.Be used for meat stagnation, stomach alkane distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain, hyperlipidemia.
Cacumen Platycladi:
Another name Cacumen Platycladi (Cacumen Biotae), Cong Baiye have cooling blood for hemostasis, antitussive action.
Folium Pini:
Another name bristles Folium Pini, Folium Pini, illawarra mountain pine palpus, Folium Pini have calmness, analgesia, effect for reducing blood fat, hypercholesterolemia reducing for the central nervous system.
Semen Vitis viniferae:
In to contain grasp seed procyanidins be the high-efficiency antioxidant agent, be the most effective free radical scavenger, can strengthen the resistance of blood vessel wall; Reduce the diabetes recurrence; Increase the soft property of skin and soft and smooth row
Herba Artemisiae Scopariae:
Another name capillary wormwood, Herba Artemisiae Sieversianae, floss Artemisia, Folium Pini Chinese mugwort etc., energy clearing away damp-heat, jaundice eliminating subcutaneous ulcer.
Radix Et Caulis Acanthopanacis Senticosi:
Another name CORTEX ACANTHOPANACIS, grain rice skin, Radix Tetrastigmatis Obovati skin have sedation to the central nervous system; The extract of Radix Acanthopanacis Senticosi root and glycoside all have resisting fatigue, antitumaous effect, can increase the nonspecific resistance of body.
Herba Taxilli:
Have another name called wide parasitism, though hypotensive effect, diuresis, Herba Polygoni Avicularis glycoside have hypotensive effect, sedation, can reduce the tension force of isolated rabbit intestinal anesthetized dog.
The Rhizoma Atractylodis Macrocephalae:
Another name Rhizoma Atractylodis Macrocephalae, winter art, Zhejiang art, kind art, invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive.
Radix Gentianae:
Another name Radix Gentianae, Radix Gentianae, Radix Gentianae have heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire action.
Compared with the prior art, the present invention is simple, the taking convenience of preparation technology not only, and can improve metabolism, lowering blood-fat and reducing weight, the sedation and analgesia, remarkable to the therapeutic effect of gout and hyperuricemia and hyperlipidemia of body.
From 1998, adopt the effect test of " multifunctional weight losing tea " in order to detect product of the present invention.
One, clinical experiment:
(1) body weight test:
At random 180 examples are suffered from the obese patient and carried out clinical experiment.
Method: two bags of every days, every bag of 5g, continuously Instant Drinks are 60, normal diet, cross-reference, 3～5kg person, 176 people that lose weight, effective 97.8%, without discomfort or side effect.
(2) hypercholesterolemia:
To suffer from hypercholesterolemia patient 128 people, be divided at random matched group 56 people and test group 72 people; Test group group member each drink the present invention every day " multifunctional weight losing tea " 5 grams, 2 times/days; And the matched group group member drinks the green tea of isodose, and number of times is identical.60 days is a course for the treatment of.
Testing result is as follows:
As can be seen from the table: the present invention not only has cleaning action but also glyceric acid fat is also had cleaning action formed cholesterol in the blood vessel.
(3) to the gout curative effect:
Randomly draw and suffer from goat patient 42 examples, male 32 examples wherein, women 10 examples, 32～48 years old age, average 40 years old; The course of disease 2～15 years, average out to 8 years.By early, middle and late, minute three times (using 5 g/bags) brew with boiled water at every turn, are used as tea and drink with the present invention's's " multifunctional weight losing tea " medicated tea, and 15 days is a course for the treatment of, adds up curative effect after 3 courses for the treatment of.During the treatment, withdraw the medicine of other treatment gout, forbid high purine diet, maror and drinks etc.After 3 courses for the treatment of, 95% remission is arranged; After continuing to take 2,68% is asymptomatic again, afterwards recurrence of return visit in a year.
Two, toxicity research:
Randomly draw body weight and be divided into 4 groups at 80 healthy mices of 18～22g male and female half and half, 20 every group.Blank group: begin to feed with normal diet and tap water to end from experiment; Model control group: feed with nutrient fodder and tap water; The diet tea group: every day gavage 18.59g crude drug/kg diet tea water extraction liquid; Vertical general graceful group: the vertical general graceful diet tea of oral 100ml/kg every day.General graceful diet tea is the finished product of buying from market.
Detection method:
Except blank group and model control group mice do as usual the diet, diet tea group gavage every day 1 time is pressed the administration of 0.5ml/20g body weight; Vertical general graceful group is mixed with equal test dose with diet tea and puts into drinking bottle, the free diet of mice.After 1 week of administration, weigh first, then put to death whole mices and separate stomach fat, precision takes by weighing fat weight.All mices respectively at 1 week of experiment beginning after, (when experiment finishes) record body weight after 2 weeks and after 3 weeks.The statistical method such as the variance analysis of experimental data usefulness completely randomized design, the LSD method of multiple comparisons, paired t-test.
2.1 diet tea is on the impact of model mice body weight
After testing for 1 week, blank group body weight is the lightest, and and all the other each group between all there were significant differences (P＜0.05), and between all the other each groups all without significant difference (P＞0.05), illustrate that obese model is successfully constructed.After 2 weeks, administration group and blank group and model control group are more all without significant difference (P＞0.05).After 3 weeks, blank group and model control group are relatively without significant difference (P＞0.05), and more all there were significant differences (P＜0.01) for 2 matched groups and 2 administration groups, lighter with the experimental group body weight.
Impact on body weight
| The n/ example | 1W body weight/g | 2W body weight/g | 3W body weight/g | |
| The blank group | 20 | 29.7±1.7 | 33.2±2.8 | 34.4±3.2 |
| Model control group | 20 | 32.6±3.0 * | 33.4±2.9 | 33.4±2.9 |
| Diet tea | 20 | 32.8±3.3 * | 31.9±2.6 | 29.5±2.6 ** |
| Vertical general graceful group | 20 | 32.0±3.4 * | 31.8±2.7 | 28.6±2.8 ** |
Result: compare * P＜0.05 with the blank group, compare * * P＜0.01 with model control group and blank group.
2.2 diet tea is on the impact of obese model mouse web portion fat weight
After 1 week of administration, the mouse web portion fat weight that gives 2 administration groups of diet tea water extraction liquid and vertical general graceful diet tea significantly is lower than model control group (P＜0.05, P＜0.01), between 2 administration groups without significant difference (P＞0.05).See Table
The stomach fat weight change
| The n/ example | Stomach fat weight/mg | |
| Blank | 20 | 657.8±204.0 |
| The model contrast | 20 | 813.5±366.4 |
| Diet tea | 20 | 565.7±315.3 * |
| Vertical general graceful group | 20 | 487.4±197.5 ** |
Test result: compare * P＜0.05, * * P＜0.012.3 with model control group.
2.3 multifunctional weight losing tea acute toxicity test:
The random choose body weight is 8 of 18～20 healthy mices that restrain, press 0.3ml/10g dosage (maximum dosage-feeding) gastric infusion with the present invention who contains raw medicinal herbs 1.6g/ml " multifunctional weight losing tea " test liquid, this concentration is the Cmax that No. 12 irrigation stomach devices can aspirate, 2 administrations in a day.The administration accumulated dose is 96.0g crude drug/kg, and this dosage is equivalent to 192 times (clinical body weight for humans is pressed 60kg and calculated, and takes medicine every day and is designated as 0.5g/kg by crude drug) of clinical people's consumption, observes a week.Result: after the week, dissect each Mus internal organs and be showed no obvious a bout of illness change.
Conclusion: have no the overt toxicity reaction.
2.4 to the hyperuricemia animal experiment:
Choose at random body weight and be divided into 6 groups 16 of 22-25g healthy mices: blank group, simulation group, 1 group of water extraction liquid, 2 groups of water extraction liquid, 1 group of alcohol extract, 2 groups of alcohol extracts.Experimental drug is water extraction liquid (0.4g/ml) and the alcohol extract (0.4g/ml) of diet tea of the present invention.
Operational approach:
With 6 groups of mices, every day is by group administration, every day 1 time, a continuous week.After administration last day 1 hour, except the blank group, all the other each groups cause mouse hyperuricemia with lumbar injection oxonic acid potassium salt 300mg/kg.After half an hour, dissect each its Level of Serum Uric Acid of treated animal blood extracting assay after the injection.
The result is as follows:
| Group | Dosage (g/kg) | The example number | Level of Serum Uric Acid (mg/l) |
| Blank group | - | 10 | 15.16±3.5 |
| The simulation group | 0.01 | 10 | 30.96±8.58** |
| Water extraction liquid 1 | 0.2 | 10 | 10.08±2.25** |
| Water extraction liquid 2 | 0.8 | 10 | 12.24±4.55** |
| Alcohol extract 1 | 0.2 | 10 | 13.86±3.26** |
| Alcohol extract 2 | 0.8 | 10 | 15.44±5.88** |
The result: * * and model group be P＜0.01 relatively.
Conclusion:
The water extraction liquid of diet tea of the present invention and alcohol extract have good inhibitory action to the blood uric acid of mice.
2.5 the impact test on the hypoxanthine oxidase in the metabolic arthritis:
Choose at random body weight and be divided into 3 groups 9 of 22-25g healthy mices: blank group, 1 group of water extraction liquid, 2 groups of water extraction liquid.Experimental drug is the water extraction liquid (0.4g/ml) of diet tea of the present invention.
Operational approach:
With 3 groups of mices, every day is by group administration, every day 1 time, a continuous week.After administration last day 1 hour, except the blank group, all the other 2 groups are caused mouse hyperuricemia with Intraperitoneal injection of hypoxanthine 1g/kg.After half an hour, dissect the activity that 3 treated animals are got its xanthine oxidase after the injection.
The result is as follows:
Conclusion:
Pharmaceutical composition aqueous extract of the present invention has obvious inhibitory action to the xanthine oxidase activity of hyperuricemia mice due to the hypoxanthine; In addition, along with the water extraction liquid measure improves, the effect of remarkable inhibition metabolic arthritis value is arranged.
The specific embodiment
Below in conjunction with embodiment the present invention is further detailed.
Embodiment 1
At first the weight portion according to crude drug takes by weighing:
The Radix Astragali 6.5 weight portions, Fructus Arctii 4.7 weight portions, Semen Cassiae 4.7 weight portions, Fructus Ligustri Lucidi 4.7 weight portions, Herba Apocyni veneti 4.7 weight portion Rhizoma amorphophalli 4.7 weight portions, Folium Nelumbinis 4.7 weight portions, Rhizoma Polygonati 3.1 weight portions, Herb Gynostemmae Pentaphylli 3.1 weight portions, Folium Crataegi 3.1 weight portions, alfalfa 3.1 weight portions, Semen Coicis 3.1 weight portions, Caulis Spatholobi 3.1 weight portions, Herba portulacae 3.1 weight portions, Rhizoma Alismatis 3.1 weight portions, Caulis Akebiae 3.1 weight portions, Radix Saposhnikoviae 3.1 weight portions, the Cortex Eucommiae 2.4 weight portions, Cortex Cinnamomi 2.4 weight portions, Radix Polygoni Multiflori 2.4 weight portions, fragrant 2.4 weight portions change, Fructus Liquidambaris 1.6 weight portions, Flos Rosae Rugosae 1.6 weight portions, Herba Centellae 1.6 weight portions, Herba Ecliptae 1.6 weight portions, Radix Bupleuri 1.6 weight portions, Radix Scutellariae 1.6 weight portions, Fructus Schisandrae Chinensis 1.6 weight portions, Fructus Crataegi 1.5 weight portions, Cacumen Platycladi 1.5 weight portions, Folium Pini 1.5 weight portions, Semen Vitis viniferae 1.5 weight portions, Herba Artemisiae Scopariae 1.5 weight portions, Radix Et Caulis Acanthopanacis Senticosi 1.5 weight portions, Herba Taxilli 1.5 weight portions, the Rhizoma Atractylodis Macrocephalae 1.5 weight portions, Radix Gentianae 1.5 weight portions.
Clean, dry, pulverized 10～20 mesh sieves after, sterilization, pack get final product.
Embodiment 2
At first the weight portion according to crude drug takes by weighing: the Radix Astragali 6 weight portions, Fructus Arctii 6.4 weight portions, Semen Cassiae 6.4 weight portions, Fructus Ligustri Lucidi 6.4 weight portions, Herba Apocyni veneti 6.4 weight portion Rhizoma amorphophalli 6.4 weight portions, Folium Nelumbinis 6.4 weight portions, Rhizoma Polygonati 3.4 weight portions, Herb Gynostemmae Pentaphylli 3.4 weight portions, Folium Crataegi 3.4 weight portions, alfalfa 3.4 weight portions, Semen Coicis 3.4 weight portions, Caulis Spatholobi 3.4 weight portions, Herba portulacae 3.4 weight portions, Rhizoma Alismatis 3.4 weight portions, Caulis Akebiae 3.4 weight portions, Radix Saposhnikoviae 3.4 weight portions, the Cortex Eucommiae 2.8 weight portions, Cortex Cinnamomi 2.8 weight portions, Radix Polygoni Multiflori 2.8 weight portions, fragrant 2.8 weight portions change, Fructus Liquidambaris 2.2 weight portions, Flos Rosae Rugosae 2.2 weight portions, Herba Centellae 2.2 weight portions, Herba Ecliptae 2.2 weight portions, Radix Bupleuri 2.2 weight portions, Radix Scutellariae 2.2 weight portions, Fructus Schisandrae Chinensis 2.2 weight portions, Fructus Crataegi 2 weight portions, Cacumen Platycladi 2 weight portions, Folium Pini 2 weight portions, Semen Vitis viniferae 2 weight portions, Herba Artemisiae Scopariae 2 weight portions, Radix Et Caulis Acanthopanacis Senticosi 2 weight portions, Herba Taxilli 2 weight portions, the Rhizoma Atractylodis Macrocephalae 2 weight portions, Radix Gentianae 2 weight portions.
Clean, dry, pulverized 10～20 mesh sieves after, sterilization, pack get final product.
Embodiment 3
At first the weight portion according to crude drug takes by weighing:
The Radix Astragali 7 weight portions, Fructus Arctii 3 weight portions, Semen Cassiae 3 weight portions, Fructus Ligustri Lucidi 3 weight portions, Herba Apocyni veneti 3 weight portion Rhizoma amorphophalli 3 weight portions, Folium Nelumbinis 3 weight portions, Rhizoma Polygonati 2.8 weight portions, Herb Gynostemmae Pentaphylli 2.8 weight portions, Folium Crataegi 2.8 weight portions, alfalfa 2.8 weight portions, Semen Coicis 2.8 weight portions, Caulis Spatholobi 2.8 weight portions, Herba portulacae 2.8 weight portions, Rhizoma Alismatis 2.8 weight portions, Caulis Akebiae 2.8 weight portions, Radix Saposhnikoviae 2.8 weight portions, the Cortex Eucommiae 2 weight portions, Cortex Cinnamomi 2 weight portions, Radix Polygoni Multiflori 2 weight portions, fragrant 2 weight portions change, Fructus Liquidambaris 1 weight portion, Flos Rosae Rugosae 1 weight portion, Herba Centellae 1 weight portion, Herba Ecliptae 1 weight portion, Radix Bupleuri 1 weight portion, Radix Scutellariae 1 weight portion, Fructus Schisandrae Chinensis 1 weight portion, Fructus Crataegi 1 weight portion, Cacumen Platycladi 1 weight portion, Folium Pini 1 weight portion, Semen Vitis viniferae 1 weight portion, Herba Artemisiae Scopariae 1 weight portion, Radix Et Caulis Acanthopanacis Senticosi 1 weight portion, Herba Taxilli 1 weight portion, the Rhizoma Atractylodis Macrocephalae 1 weight portion, Radix Gentianae 1 weight portion.
Clean, dry, pulverized 10～20 mesh sieves after, sterilization, pack get final product.
Embodiment 4
At first the weight portion according to crude drug takes by weighing:
The Radix Astragali 6 weight portions, Fructus Arctii 5 weight portions, Semen Cassiae 5 weight portions, Fructus Ligustri Lucidi 5 weight portions, Herba Apocyni veneti 4 weight portion Rhizoma amorphophalli 4 weight portions, Folium Nelumbinis 4 weight portions, Rhizoma Polygonati 3 weight portions, Herb Gynostemmae Pentaphylli 3 weight portions, Folium Crataegi 3 weight portions, alfalfa 3 weight portions, Semen Coicis 3 weight portions, Caulis Spatholobi 3 weight portions, Herba portulacae 3 weight portions, Rhizoma Alismatis 3 weight portions, Caulis Akebiae 3 weight portions, Radix Saposhnikoviae 3 weight portions, the Cortex Eucommiae 2.5 weight portions, Cortex Cinnamomi 2.5 weight portions, Radix Polygoni Multiflori 2.5 weight portions, fragrant 2.5 weight portions change, Fructus Liquidambaris 2 weight portions, Flos Rosae Rugosae 2 weight portions, Herba Centellae 2 weight portions, Herba Ecliptae 2 weight portions, Radix Bupleuri 2 weight portions, Radix Scutellariae 2 weight portions, Fructus Schisandrae Chinensis 1.5 weight portions, Fructus Crataegi 1.5 weight portions, Cacumen Platycladi 1.5 weight portions, Folium Pini 1.5 weight portions, Semen Vitis viniferae 1.5 weight portions, Herba Artemisiae Scopariae 1.5 weight portions, Radix Et Caulis Acanthopanacis Senticosi 1.5 weight portions, Herba Taxilli 1.5 weight portions, the Rhizoma Atractylodis Macrocephalae 1.5 weight portions, Radix Gentianae 1.5 weight portions.
Clean, dry, pulverized 10～20 mesh sieves after, sterilization, pack get final product.
Claims (2)
1. multifunctional weight losing tea is characterized in that it is to be made by the crude drug of following weight proportion:
The Radix Astragali 6～7 weight portions, Fructus Arctii 3～6.4 weight portions, Semen Cassiae 3～6.4 weight portions, Fructus Ligustri Lucidi 3～6.4 weight portions, Herba Apocyni veneti 3～6.4 weight portion Rhizoma amorphophalli 3～6.4 weight portions, Folium Nelumbinis 3～6.4 weight portions, Rhizoma Polygonati 2.8～3.4 weight portions, Herb Gynostemmae Pentaphylli 2.8～3.4 weight portions, Folium Crataegi 2.8～3.4 weight portions, alfalfa 2.8～3.4 weight portions, Semen Coicis 2.8～3.4 weight portions, Caulis Spatholobi 2.8～3.4 weight portions, Herba portulacae 2.8～3.4 weight portions, Rhizoma Alismatis 2.8～3.4 weight portions, Caulis Akebiae 2.8～3.4 weight portions, Radix Saposhnikoviae 2.8～3.4 weight portions, the Cortex Eucommiae 2～2.8 weight portions, Cortex Cinnamomi 2～2.8 weight portions, Radix Polygoni Multiflori 2～2.8 weight portions, repeatedly fragrant 2～2.8 weight portions, Fructus Liquidambaris 1～2.2 weight portion, Flos Rosae Rugosae 1～2.2 weight portion, Herba Centellae 1～2.2 weight portion, Herba Ecliptae 1～2.2 weight portion, Radix Bupleuri 1～2.2 weight portion, Radix Scutellariae 1～2.2 weight portion, Fructus Schisandrae Chinensis 1～2.2 weight portion, Fructus Crataegi 1～2 weight portion, Cacumen Platycladi 1～2 weight portion, Folium Pini 1～2 weight portion, Semen Vitis viniferae 1～2 weight portion, Herba Artemisiae Scopariae 1～2 weight portion, Radix Et Caulis Acanthopanacis Senticosi 1～2 weight portion, Herba Taxilli 1～2 weight portion, the Rhizoma Atractylodis Macrocephalae 1～2 weight portion, Radix Gentianae 1～2 weight portion.
2. multifunctional weight losing tea according to claim 1 is characterized in that it is to be made by the crude drug of following weight proportion:
The Radix Astragali 6.5 weight portions, Fructus Arctii 4.7 weight portions, Semen Cassiae 4.7 weight portions, Fructus Ligustri Lucidi 4.7 weight portions, Herba Apocyni veneti 4.7 weight portion Rhizoma amorphophalli 4.7 weight portions, Folium Nelumbinis 4.7 weight portions, Rhizoma Polygonati 3.1 weight portions, Herb Gynostemmae Pentaphylli 3.1 weight portions, Folium Crataegi 3.1 weight portions, alfalfa 3.1 weight portions, Semen Coicis 3.1 weight portions, Caulis Spatholobi 3.1 weight portions, Herba portulacae 3.1 weight portions, Rhizoma Alismatis 3.1 weight portions, Caulis Akebiae 3.1 weight portions, Radix Saposhnikoviae 3.1 weight portions, the Cortex Eucommiae 2.4 weight portions, Cortex Cinnamomi 2.4 weight portions, Radix Polygoni Multiflori 2.4 weight portions, fragrant 2.4 weight portions change, Fructus Liquidambaris 1.6 weight portions, Flos Rosae Rugosae 1.6 weight portions, Herba Centellae 1.6 weight portions, Herba Ecliptae 1.6 weight portions, Radix Bupleuri 1.6 weight portions, Radix Scutellariae 1.6 weight portions, Fructus Schisandrae Chinensis 1.6 weight portions, Fructus Crataegi 1.5 weight portions, Cacumen Platycladi 1.5 weight portions, Folium Pini 1.5 weight portions, Semen Vitis viniferae 1.5 weight portions, Herba Artemisiae Scopariae 1.5 weight portions, Radix Et Caulis Acanthopanacis Senticosi 1.5 weight portions, Herba Taxilli 1.5 weight portions, the Rhizoma Atractylodis Macrocephalae 1.5 weight portions, Radix Gentianae 1.5 weight portions.
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| CN103041061A (en) * | 2013-01-18 | 2013-04-17 | 崔苡菱 | Stasis-dissolving and pulse-invigorating powder |
| CN103301436A (en) * | 2013-06-21 | 2013-09-18 | 王燕华 | Medicine for loosing weight and reducing fat |
| CN103392880A (en) * | 2013-08-08 | 2013-11-20 | 常熟市海虞茶叶有限公司 | Medical health-care tea leaves |
| CN103583736A (en) * | 2013-10-22 | 2014-02-19 | 朱霞 | Tea cream for strengthening spleen and clearing abdominal dropsy and preparation method thereof |
| CN103719496A (en) * | 2013-12-31 | 2014-04-16 | 青岛恒波仪器有限公司 | Hawthorn leaf health-care tea for reducing fat and losing weight and preparation method thereof |
| CN103734425A (en) * | 2013-12-31 | 2014-04-23 | 青岛恒波仪器有限公司 | Health-care Chinese hawthorn leaf tea capable of reducing glucose and lipid and preparation method of tea |
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| CN104068174A (en) * | 2014-06-27 | 2014-10-01 | 郑文和 | Healthy tea |
| CN104489195A (en) * | 2014-12-18 | 2015-04-08 | 蒙城县科技创业服务中心 | Lotus leaf-fresh ginger tea capable of reducing blood fat |
| CN105533016A (en) * | 2015-12-09 | 2016-05-04 | 叶国生 | Weight reducing tea beverage |
| CN105746780A (en) * | 2016-03-25 | 2016-07-13 | 梧州市中茗茶业有限公司 | Diet Liubao tea and preparation method thereof |
| CN106333000A (en) * | 2015-07-11 | 2017-01-18 | 谭汉卿 | Health protection tea for reducing fat and improving eyesight |
| CN106417756A (en) * | 2016-09-27 | 2017-02-22 | 聂光永 | Healthy tea |
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| CN103041061B (en) * | 2013-01-18 | 2015-01-07 | 崔苡菱 | Stasis-dissolving and pulse-invigorating powder |
| CN103041061A (en) * | 2013-01-18 | 2013-04-17 | 崔苡菱 | Stasis-dissolving and pulse-invigorating powder |
| CN103301436A (en) * | 2013-06-21 | 2013-09-18 | 王燕华 | Medicine for loosing weight and reducing fat |
| CN103392880A (en) * | 2013-08-08 | 2013-11-20 | 常熟市海虞茶叶有限公司 | Medical health-care tea leaves |
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| CN103830374B (en) * | 2014-03-06 | 2016-06-08 | 天津中医药大学 | The application in hyperuricemia clearly of three leaf glycolipids |
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| CN103830675A (en) * | 2014-03-06 | 2014-06-04 | 庄妍 | Pharmaceutical composition for treating hyperlipemia |
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| CN106417756A (en) * | 2016-09-27 | 2017-02-22 | 聂光永 | Healthy tea |
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| EP3991801A1 (en) * | 2020-11-03 | 2022-05-04 | UAB "Bioklinika" | Composition for improving skin condition containing plant extracts |
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