Background technology
Gastroptosis is meant when standing that the lower edge of stomach reaches pelvic cavity, and lesser gastric curvature camber line minimum point is reduced to below the crista iliaca line.Clinical diagnosis is main with X line, barivm meal fluoroscopy (screem), ultrasound diagnosis.Slight sagging person is generally asymptomatic, and sagging obvious person abdominal distention, stomachache can occur, feels sick, vomiting, constipation, insomnia, headache, giddy, blunt, hypotension, cardio palmus shape.Modern medicine is thought: gastroptosis is a kind of functional disease, because pipe smooth muscle or ligament is loose causes.Still there is not effective cure method.
Chinese medicine is summarised as taste with its pathogenesis and becomes estranged, deficiency of QI in middle-JIAO, filling under the deficiency of vital energy.Can be divided into following several kinds of situation according to the cause of disease:
1, the strongly fragrant native harmony of wood is received rotten ineffective.The rule of treatment: flat invigorating primordial QI.
2, water is wet does not transport deficiency of QI in middle-JIAO.The rule of treatment: invigorating the spleen for eliminating dampness.
3, stagnated QI transforming into fire, accumulation of heat stomach mansion.The rule of treatment: dispersing the stagnated liver-QI for regulating the stomach.
4, eating and drinking without temperance, stomach-QI being unable to descend normally, gallbladder loses catharsis.The rule of treatment: function of gallbladder promoting helps digestion.
5, logical falling become estranged, and clear sun sink.The rule of treatment: transfer the livering stasis of blood.
The present Research of medical material involved in the present invention is following:
Rhizoma Cimicifugae: [source] these article are the big SANYE Rhizoma Cimicifugae of cohosh Cimici, uga heracLei, the dry rhizome of oliaKom., Rhizoma Cimicifugae Cimici uga dahurica (Turcz.) Maxim. of Xingan or Rhizoma Cimicifugae Cimici fuga foetida L.[meridian distribution of property and flavor] is hot, little sweet, is slightly cold.Return lung, spleen, stomach, large intestine channel.[function cures mainly] delivered rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.Be used for headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome is sent out speckle, proctoptosis, uterine prolapse.[usage and dosage] 3~lOg.
The Radix Astragali: [source] these article are the dry root of leguminous plant Radix Astagali Astragalus membranaceus (Fisch) Bge.var.mongholicus (Bge) Hsiao or Radix Astragali Astragalus membranaceus (Fisch) Bge..[meridian distribution of property and flavor] is sweet, tepor.Return lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.It is weak to be used for the deficiency of vital energy, anorexia and loose stool, and sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst for a long time and do not hold back, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.[usage and dosage] 9~30g.
Radix Codonopsis: [source] these article are the dry root of campanulaceae plant Radix Codonopsis Codonopsispilosula (Franch.) Nannf., plain flower Radix Codonopsis CodonopsispilosulaNannf.var.modesta (Nannf.) L.T.Shen or radix codonpsis tangshen Codonopsistangshen Oliv..[meridian distribution of property and flavor] is sweet, and be flat.Return spleen, lung meridian.[function cures mainly] invigorating the spleen and replenishing QI, the spleen invigorating lung benefiting.Be used for deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, the dyspnea due to deficiency cough, interior-heat is quenched one's thirst.[usage and dosage] 9~30g.
Rhizoma Dioscoreae: [source] these article are the dry rhizome of Dioscoreaceae plant Rhizoma Dioscoreae Dioscorea opposita Thunb..[meridian distribution of property and flavor] is sweet, and be flat.Return spleen, dried meat, kidney channel.[function cures mainly] spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.Be used for insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.The Rhizoma Dioscoreae (parched with bran) spleen reinforcing is good for the stomach.Be used for insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, leukorrhagia.[usage and dosage] 15~30g.
Poria: [source] these article are the dry sclerotia of Polyporaceae fungus Poria Poriacocos (Schw.) Wolf.[meridian distribution of property and flavor] is sweet, light, and be flat.GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, the spleen invigorating mind calming.Be used for the edema oliguria, the phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in the loose stool, irritability, palpitation with fear insomnia.[usage and dosage] 9~15g.
Radix Angelicae Sinensis: [source] these article are the dry root of umbelliferae angelica Angelica sin:ensis (Oliv.) Diels.[meridian distribution of property and flavor] is sweet, hot, temperature.Return liver, the heart, spleen channel.[function cures mainly] enriched blood and invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.The Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.Be used for the amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.[usage and dosage] 6~12g.
Radix Bupleuri: [source] these article are the dry root of umbelliferae bupleurum BupleurumchinenseDC. or Radix Bupeuri Scorzonerfolii. Bupleurum scorzonerifoliumWilld..[meridian distribution of property and flavor] hardship is slightly cold.Return liver, gallbladder meridian.[function cures mainly] reconciling superficies and interior, soothing the liver, yang invigorating.Be used for cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.[usage and dosage] 3~9g.
Radix Curcumae: [source] these article are zingiberaceous plant RADIX CURCUMAE Curcuma rcenyujin Y, the dried root of H. Chenet C.Ling, Rhizoma Curcumae Longae Curcuma longaL., Guangxi zedoary Curcumakwangsiensis S.G.Lee et C.F.Liang or Rhizoma Curcumae Curcuma pha eocaulis Val..[meridian distribution of property and flavor] is hot, bitter, and be cold.Return liver, the heart, lung meridian.[function cures mainly] promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice.Be used for the twinge of the breast side of body, obstruction of qi in the chest and cardialgia, the amenorrhea dysmenorrhea, distending pain of the breast, the calentura coma, epilepsy is gone mad, and heat in blood is told nosebleed, the jaundice dark coloured urine.[usage and dosage] 3~lOg.
Carapax Trionycis: [source] these article are the carapace of Trionychidae animal Trionyx sinensis Wiegmann TrionyxsinensisWiegmann.[meridian distribution of property and flavor] is salty, is slightly cold.Return liver, kidney channel.[function cures mainly] nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving is brought down a fever to remove and is steamed.Be used for fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, stirring-up of pathogenic wind in the interior resulting from deficiency, amenorrhea , WEIJIA, chronic malaria malaria with splenomegaly.[usage and dosage] 9~24g.
Fructus Aurantii Immaturus: [source] these article are the dry young fruit of rutaceae Citrus aurantium Linn. CitrusaurantiumL. and variety or Fructus Citri sinensis CitrussinensisOsbeck.[meridian distribution of property and flavor] is bitter, hot, sour, temperature.Return spleen, stomach warp.[function cures mainly] dispelling the stagnated QI removing food stagnancy, the diffusing painful abdominal mass of reducing phlegm.Be used for stopping in stagnant, the feeling of fullness distending pain, heavy behind the dysentery, constipation, the expectorant vapour lock thoracic obstruction that stagnates, blocked-up chest; Gastroptosis, proctoptosis, uterine prolapse.[usage and dosage] 3~9g.
Radix Polygoni Multiflori: [source] these article are the dried root of polygonum multiflorum thunb Polygortum muLti florum Thunb..[meridian distribution of property and flavor] is bitter, sweet, puckery, tepor.Return liver, the heart, kidney channel.[function cures mainly] detoxifcation, eliminating carbuncle, preventing the attack (or recurrence) of malaria, loosening bowel to relieve constipation.Be used for carbuncle sore, scrofula, the rubella pruritus, the chronic malaria body is empty, the dryness of the intestine constipation.[usage and dosage] 3~6g.
Fructus Corni: [source] these article are the drying and ripening sarcocarp of Cornaceae plant Fructus Corni Cornus oj-jZcinalis Sieb. etZucc..[meridian distribution of property and flavor] acid, puckery, tepor.Return liver, kidney channel.[function cures mainly] liver and kidney tonifying, arresting collape syndrome by astringents.Be used for dizzy ear toot, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating collapse, interior-heat is quenched one's thirst.[usage and dosage] 6~12g.
Fructus Lycii: [source] these article are the dry mature fruit of plant of Solanaceae lycium barbarum Lycium barbarum L..[meridian distribution of property and flavor] is sweet, and be flat.Return liver, kidney channel.[function cures mainly] nourishing the liver and kidney, replenishing vital essence to improve eyesight.Be used for the asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, impotence and seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.[usage and dosage] 6~12g.
Radix Panacis Quinquefolii: [source] these article are sweet, the little hardship of Araliaceae Radix Panacis Quinquefolii Pan.ax quin.que folium L. [meridian distribution of property and flavor], cold.GUIXIN, lung, kidney channel.[function cures mainly] boosting qi and nourishing yin, clearing away heat and promoting production of body fluid.It is thanks to cloudy to be used for the deficiency of vital energy, and deficiency-heat is tired tired, cough with asthma expectorant blood, and interior-heat is quenched one's thirst, dryness of the mouth and throat.[usage and dosage] 3~6g.
Fructus Jujubae: [source] these article are the dry mature fruit of Rhamnaceae plant Fructus Jujubae ZiziphusjujubaMill..[meridian distribution of property and flavor] is sweet, temperature.Return spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.Be used for insufficiency of the spleen lack of appetite, weak loose stool, woman hysteria.[usage and dosage] 6~15g.
The Radix Aucklandiae: [source] these article are the dry root of feverfew Radix Aucklandiae 4ucklandia lappa Decne..[meridian distribution of property and flavor] is hot, bitter, temperature.Return spleen, stomach, large intestine, three warmers, gallbladder meridian.[function cures mainly] promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.Be used for the breast side of body, abdominal distention, heavy behind the dysentery, food stagnation does not disappear, anorexia.The real intestinal antidiarrheal of Radix Aucklandiae (roasted).Stomachache is used to have loose bowels.[usage and dosage] 3~6g.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine and method for distilling thereof of flat invigorating primordial QI treatment gastroptosis; Through selecting suitable medical material and proportioning thereof and formulate the method for distilling of its patent medicine, the purpose that reaches the flat safe and effective treatment gastroptosis of invigorating primordial QI and make it be suitable for applying clinically.
In order to achieve the above object, the present invention adopts following technical scheme:
A kind of Chinese medicine of flat invigorating primordial QI treatment gastroptosis is made up of the medical material of following weight proportion: Rhizoma Cimicifugae 3-10 part, Radix Astragali 9-30 part, Radix Codonopsis 9-30 part, Rhizoma Dioscoreae 15-30 part, Poria 9-15 part, Radix Angelicae Sinensis 6-12 part, Radix Bupleuri 3-9 part, Radix Curcumae 3-10 part, Carapax Trionycis 9-24 part, Fructus Aurantii Immaturus 3-9 part, Radix Polygoni Multiflori 3-6 part, Fructus Corni 6-12 part, Fructus Lycii 6-12 part, Radix Panacis Quinquefolii 3-6 part, Fructus Jujubae 6-15 part, Radix Aucklandiae 3-6 part.
The optimum weight proportioning of each medical material of Chinese medicine of the present invention is: 8 parts of Rhizoma Cimicifugaes, 20 parts of the Radixs Astragali, 20 parts of Radix Codonopsis, 20 parts of Rhizoma Dioscoreaes, 10 parts in Poria, 10 parts of Radix Angelicae Sinensis, 6 parts of Radix Bupleuri, 6 parts of Radix Curcumaes, 12 parts of Carapax Trionycis, 5 parts of Fructus Aurantii Immaturuss, 5 parts of Radix Polygoni Multiflori, 10 parts of Fructus Corni, 10 parts of Fructus Lycii, 4 parts of Radix Panacis Quinquefoliis, 8 parts in Fructus Jujubae, 5 parts of the Radix Aucklandiae.
The method for distilling of Chinese medicine of the present invention is: take by weighing said medicinal materials in part by weight; Decocte with water 2-3 time; Merge decoction liquor; Concentrate, get extract.
Usage and dosage: oral.Normal adult is taken by " Rhizoma Cimicifugae 3-10 gram; Radix Astragali 9-30 gram; Radix Codonopsis 9-30 gram; Rhizoma Dioscoreae 15-30 gram; Poria 9-15 gram; Radix Angelicae Sinensis 6-12 gram every day; Radix Bupleuri 3-9 gram; Radix Curcumae 3-10 gram; Carapax Trionycis 9-24 gram; Fructus Aurantii Immaturus 3-9 gram; Radix Polygoni Multiflori 3-6 gram; Fructus Corni 6-12 gram; Fructus Lycii 6-12 gram; Radix Panacis Quinquefolii 3-6 gram; Fructus Jujubae 6-15 gram; Radix Aucklandiae 3-6 gram " especially " Rhizoma Cimicifugae 8 restrains; The Radix Astragali 20 grams; Radix Codonopsis 20 grams; Rhizoma Dioscoreae 20 grams; Poria 10 grams; Radix Angelicae Sinensis 10 grams; Radix Bupleuri 6 grams; Radix Curcumae 6 grams; Carapax Trionycis 12 grams; Fructus Aurantii Immaturus 5 grams; Radix Polygoni Multiflori 5 grams; Fructus Corni 10 grams; Fructus Lycii 10 grams; Radix Panacis Quinquefolii 4 grams; Fructus Jujubae 8 grams; The Radix Aucklandiae 5 gram " preparation that after extraction, makes.Can be divided into 2-3 time takes.
The beneficial effect that we are bright:
Chinese medicine is thought, should adopt the strongly fragrant native harmony of method treatment wood of flat invigorating primordial QI, the rotten ineffective gastroptosis that causes of receiving.Chinese medicine of the present invention is selected for use: the Radix Astragali, Radix Codonopsis, Radix Panacis Quinquefolii, Fructus Jujubae benefit invigorating middle warmer gas; Radix Polygoni Multiflori, Radix Curcumae, the liver heat removing of Radix Aucklandiae toxin expelling, the spleen invigorating circulation of qi promoting; Rhizoma Cimicifugae, Radix Bupleuri elevate a turnable ladder yang-energy; The Fructus Corni convergence is taken off admittedly.Thereby carry invigorating middle warmer gas, yang invigorating takes off admittedly.Simultaneously, use: kidney is supported in Carapax Trionycis, Fructus Lycii YIN nourishing; Chinese angelica blood supplementing is invigorated blood circulation, thus strengthening the body resistance.Use: Rhizoma Dioscoreae, Poria strengthening the spleen and nourishing the stomach, alleviate malaise symptoms.All medicines share, and play flat invigorating primordial QI altogether, carry invigorating middle warmer gas, restrain and take off admittedly, simultaneously the effect of strengthening the body resistance, strengthening the spleen and nourishing the stomach.
Clinical trial confirms, medicine of the present invention can be equalled invigorating primordial QI and treated the strongly fragrant native harmony of wood safely and effectively, receives the rotten ineffective gastroptosis that causes; Find out that easily easy extraction of the present invention, environmental protection are fit to produce and clinical practice.
Below in conjunction with clinical testing data beneficial effect of the present invention is described:
From year November in November, 2005 to 2010, inventor's granule that hospital application optimal drug proportioning of the present invention makes in the ocean, Yantai treatment gastroptosis is received better effects.
1, physical data
The strongly fragrant native harmony of wood is received the rotten ineffective gastroptosis patient who causes totally 100 examples, is divided into two groups at random, and 50 examples are organized in treatment, matched group 50 examples, and two groups are not all had significant difference at aspects such as sex, age, protopathy, the feelings order of severity, treatment, the courses of disease.
2, method
Matched group gives BUZHONG YIQI WAN 3g/inferior, every day 2 times, treats 1 month; The treatment group gives the granule that optimal drug proportioning of the present invention makes, and every day 2 times, treats 1 month.
3, criterion of therapeutical effect
The recovery from illness: through x line barivm meal fluoroscopy (screem) gastric angle more than two crista iliaca lines, the clinical symptoms complete obiteration.
Produce effects: move to former saggingly more than 1/2 on the x line barivm meal fluoroscopy (screem) body of stomach, the clinical symptoms work improves.
Take a turn for the better: move on the x line barivm meal fluoroscopy (screem) body of stomach but not enough former sagging 1/2, partial symptoms is improved.
Invalid: barivm meal fluoroscopy (screem) of x line and symptom all do not have change.
4, statistical method adopts the SPSS statistical software to analyze.
5, therapeutic outcome
Two groups of clinical efficacies are relatively seen table 1.
Table 1 liang group clinical efficacy relatively
Group |
n |
Recovery from illness |
Take a turn for the better |
Invalid |
Total effective rate (%) |
The treatment group |
50 |
41 |
8 |
1 |
98% |
Matched group |
50 |
23 |
21 |
6 |
88% |
Two groups of therapeutic processes are not all found obvious adverse reaction.It is thus clear that the medicine that the best proportioning of the present invention makes is used to treat the strongly fragrant native harmony of wood, it is high to receive the rotten ineffective gastroptosis drug safety that causes, cure rate.
According to above-mentioned clinical experiment data; In conjunction with prescription mechanism of the present invention and general knowledge known in this field; Those skilled in the art know by inference easily; Medical material among utilization the present invention; Get the weight proportion that its conventional amount used converts and obtains, i.e. Rhizoma Cimicifugae 3-10 part, Radix Astragali 9-30 part, Radix Codonopsis 9-30 part, Rhizoma Dioscoreae 15-30 part, Poria 9-15 part, Radix Angelicae Sinensis 6-12 part, Radix Bupleuri 3-9 part, Radix Curcumae 3-10 part, Carapax Trionycis 9-24 part, Fructus Aurantii Immaturus 3-9 part, Radix Polygoni Multiflori 3-6 part, Fructus Corni 6-12 part, Fructus Lycii 6-12 part, Radix Panacis Quinquefolii 3-6 part, Fructus Jujubae 6-15 part, Radix Aucklandiae 3-6 part, also can obtain with optimum weight of the present invention prepare medicine similar techniques effect.
The specific embodiment
In order to understand better and embodiment of the present invention, further specify the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take by weighing Rhizoma Cimicifugae 8 grams, the Radix Astragali 20 grams, Radix Codonopsis 20 grams, Rhizoma Dioscoreae 20 grams, Poria 10 grams, Radix Angelicae Sinensis 10 grams, Radix Bupleuri 6 grams, Radix Curcumae 6 grams, Carapax Trionycis 12 grams, Fructus Aurantii Immaturus 5 grams, Radix Polygoni Multiflori 5 grams, Fructus Corni 10 grams, Fructus Lycii 10 grams, Radix Panacis Quinquefolii 4 grams, Fructus Jujubae 8 grams, the Radix Aucklandiae 5 grams; Add 8 times of water gagings, decocted 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate concentrates, and drying incapsulates shell, promptly gets the capsule that meets one day consumption of normal adult.
Be used to treat the strongly fragrant native harmony of wood, receive the rotten ineffective gastroptosis that causes.Oral, divide sooner or later every day and take for twice.
Specific embodiment 2
Take by weighing Rhizoma Cimicifugae 3 grams, the Radix Astragali 9 grams, Radix Codonopsis 9 grams, Rhizoma Dioscoreae 15 grams, Poria 9 grams, Radix Angelicae Sinensis 6 grams, Radix Bupleuri 3 grams, Radix Curcumae 3 grams, Carapax Trionycis 9 grams, Fructus Aurantii Immaturus 3 grams, Radix Polygoni Multiflori 3 grams, Fructus Corni 6 grams, Fructus Lycii 6 grams, Radix Panacis Quinquefolii 3 grams, Fructus Jujubae 6 grams, the Radix Aucklandiae 3 grams; Add 10 times of water gagings, decocted 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate concentrates, drying, and packing promptly gets the powder that meets one day consumption of normal adult.
Be used to treat the strongly fragrant native harmony of wood, receive the rotten ineffective gastroptosis that causes.Oral, divide sooner or later every day and take for twice.
Specific embodiment 3
Take by weighing Rhizoma Cimicifugae 10 grams, the Radix Astragali 30 grams, Radix Codonopsis 30 grams, Rhizoma Dioscoreae 30 grams, Poria 15 grams, Radix Angelicae Sinensis 12 grams, Radix Bupleuri 9 grams, Radix Curcumae 10 grams, Carapax Trionycis 24 grams, Fructus Aurantii Immaturus 9 grams, Radix Polygoni Multiflori 6 grams, Fructus Corni 12 grams, Fructus Lycii 12 grams, Radix Panacis Quinquefolii 6 grams, Fructus Jujubae 15 grams, the Radix Aucklandiae 6 grams; Add 6 times of water gagings, decoct 3 times, decocted 1 hour at every turn, merge decoction liquor, concentrate, add an amount of dextrin and correctives, granulate according to this area common process, packing can make the granule that meets one day consumption of normal adult.
Be used to treat the strongly fragrant native harmony of wood, receive the rotten ineffective gastroptosis that causes.Oral, divide every day take three times morning, noon and afternoon.