CN1562160A - Composite medicine for treating hepatitis B complication - Google Patents
Composite medicine for treating hepatitis B complication Download PDFInfo
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- CN1562160A CN1562160A CN 200410017960 CN200410017960A CN1562160A CN 1562160 A CN1562160 A CN 1562160A CN 200410017960 CN200410017960 CN 200410017960 CN 200410017960 A CN200410017960 A CN 200410017960A CN 1562160 A CN1562160 A CN 1562160A
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Abstract
A Chinese medicine for treating hepatitis B and its complication is prepared from 11 Chinese-medicinal materials including bupleurum root, white peony root, curcuma root, wild chrysanthemum flower, etc.
Description
Technical field
The present invention relates to a kind of prescription medicine for the treatment of the hepatitis B complication.
Background technology
Hepatitis B is that the clinician treats more thorny a kind of infectious disease.Human body, propagation are very wide, infectiousness is stronger, very harmful, the course of treatment slow because hepatitis B virus is invaded easily, eliminating virus difficulty, have multiple complications simultaneously, and it is the important difficult problem that current medicine and pharmacology are worth research and tackling key problem.
Summary of the invention
Purpose of the present invention just provides a kind of treatment hepatitis B complication prescription medicine, and it with the different different hepatitis Bs of prescription treatment, suits the remedy to the case determined curative effect by forming at the dialectical prescription of controlling of executing of various hepatitis B complication to state of an illness pathological changes.
Treatment hepatitis B complication prescription medicine of the present invention is to be made by following weight portion crude drug: (below be weight portion)
Radix bupleuri 15 root of herbaceous peony 20-40 root tubers of aromatic turmeric 10 oriental wormwoods 30 adder-worts 15 mother chrysanthemums 15 stringy stonecrops 30 oldenlandia diffusas 30 Herba Scutellariae Barbataes 30 Paris polyphylla 20 honeysuckle flowers 15 isatis roots 30 giant knotweeds 20 rheum officinale 10-30 Radix Angelicae Sinensis 15 red sage root 10-20 radix paeoniae rubrathe 10-15 dried rhizome of rehmannia 15 fleece-flower root 15-30 dutchmanspipe roots 10 barks of official magnolia 15 rhizoma cyperis 15 Buddha's hands 10 Radix Astragali 30-90 Radix Codonopsis 15-30 fruits of Chinese wolfberry 25 fruit of glossy privet 15-30 bighead atractylodes rhizomes 15 Poria cocos 20-90 hawthorn 30 Divine Comedy 10-20 Radix Glycyrrhizae 6-10.
Above-mentioned component is basic component, is basic medicine by its medicine of making, is applicable to that treating the concurrent hepatitis A of hepatitis B does not have ascites, no liver cirrhosis disease.
A kind of medicine for the treatment of the concurrent seminal emission disease of hepatitis B is also to include in above-mentioned basic component: Radix Polygalae 15, Semen Ziziphi Spinosae 20, Semen Platycladi 20, Arillus Longan 30, Fructus Corni 20, Herba Cistanches 15, Semen Cuscutae 20, Semen Astragali Complanati 10, Fructus Schisandrae Chinensis 20.
A kind of medicine for the treatment of the concurrent liver cirrhosis disease of hepatitis B is also to include Squama Manis 15-20, rhizoma sparganic 10, Rhizoma Curcumae 10, pink 10, Flos Carthami 8, Carapax Trionycis 60, Herba Dendrobii 30, Radix Adenophorae (Radix Glehniae) 30-50, Radix Ophiopogonis 30-50, Radix Asparagi 30-50 in above-mentioned basic component.
A kind of medicine for the treatment of the concurrent cirrhotic ascites of hepatitis B is also to include Pericarpium Arecae 20, Semen Pharbitidis 20, Semen Plantaginis 30, Caulis Akebiae 15 on the basis of the medicine for the treatment of the concurrent liver cirrhosis disease of hepatitis B.
Treatment hepatitis B complication prescription medicine of the present invention be prepared into any pharmaceutical dosage form that is suitable for using clinically, as powder, tablet, pill or oral liquid.
The preparation method of treatment hepatitis B complication prescription medicine of the present invention is:
1, the each component raw material powder is broken into 100 orders;
2, the component raw material mix homogeneously after will pulverizing again;
3, make powder by the 150 gram packs of every bag of content of dispersion.
Treatment hepatitis B complication of the present invention is applicable to that treating the concurrent hepatitis A of hepatitis B does not have in the medicine of ascites, no liver cirrhosis disease: Radix Bupleuri: return liver, gallbladder meridian, energy reducing fever by reconciliation, dispersing the stagnated live-QI to relieve the stagnation of QI.The Radix Paeoniae Alba: return Liver Channel, energy nourishing blood to suppress the hyperactive liver, relieving spasm to stop pain, yin fluid astringing YANG hyperactivity suppressing.Radix Curcumae: GUIXIN, liver, gallbladder meridian, can promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, removing heat from blood, clear away heart-fire, function of gallbladder promoting, jaundice eliminating, liver and gall are interdependent mutually, gallbladder can facilitating digestion.The through Liver Channel of all medicines of above-mentioned three medicines energy tying-in is so be the monarch drug of this medicine.Herba Artemisiae Scopariae: return spleen, stomach, liver, gallbladder meridian, energy clearing away heat-damp and promoting diuresis, jaundice eliminating are treatment first, second icterohepatitis key medicines.Rhizoma Bistortae: return Liver Channel, the energy heat-clearing and toxic substances removing, diffusing carbuncle dries.Flos Chrysanthemi Indici: return Liver Channel, energy heat-clearing and toxic substances removing, suppressing the hyperactive liver are the key medicines of treatment viral hepatitis.Herba Sedi: return liver, gallbladder, small intestine meridian, energy heat-clearing and toxic substances removing, dampness removing, this product is to acute and chronic hepatitis, chronic persistent hepatitis, and icterohepatitis is all effective in cure, and transaminase lowering is had good effect.Flos Lonicerae: sweet cold, energy heat-clearing and toxic substances removing.Herba Hedyotidis Diffusae: GUIXIN, liver, spleen channel, energy heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling.Rhizoma Paridis: have another name called Rhizoma Paridis, return the liver and gall warp, energy heat-clearing and toxic substances removing, reducing swelling and alleviating pain, dispelling wind and relieving convulsion are the key medicines of hepatitis virus resisting.Radix Isatidis: bitter cold, energy heat-clearing and toxic substances removing, removing heat from blood, sore-throat relieving are beneficial to the acute and chronic icteric infectious hepatitis of treatment.Rhizoma Polygoni Cuspidati: return liver, gallbladder, lung meridian, the analgesic therapy of invigorating blood circulation, clearing away heat-damp and promoting diuresis detoxifcation, preventing phlegm from forming and stopping coughing.Radix Et Rhizoma Rhei: return stomach, spleen, large intestine, pericardium channel, energy stasis removing, purging fire and cooling blood, blood circulation promoting and blood stasis dispelling, the alleviating jaundice jaundice eliminating is a treatment hepatitis constipation key medicine.More than counting medicine is the ministerial drug of this medicine.Radix Angelicae Sinensis: be liver, the heart, spleen channel, can enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Radix Salviae Miltiorrhizae: GUIXIN, pericardium, Liver Channel, energy promoting blood circulation and cooling blood, tranquilizing by nourishing the heart.Radix Paeoniae Rubra: GUIXIN, pericardium, Liver Channel, energy clearing away heat and cooling blood, stasis-dispelling and pain-killing.The Radix Rehmanniae: GUIXIN, liver, kidney channel, energy clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting.Radix Polygoni Multiflori: GUIXIN, liver, kidney channel, energy invigorating the liver and kidney, benefiting essence-blood relieving constipation, detoxifcation.Radix Aristolochiae: return liver, kidney, stomach warp, the energy promoting the circulation of QI to relieve pain, removing toxic substances and promoting subsidence of swelling, this product has again wards off dirty merit, unsuitable overdose.Cortex Magnoliae Officinalis: return stomach, lung, large intestine channel, the circulation of qi promoting of energy dampness, lowering the adverse QI to relieve asthma, this product is used for treating upward invasion of liver-QI, taste are done to expand good effect.Rhizoma Cyperi: return liver, tri-jiao channel, can regulate the flow of vital energy resolving depression, menstruction regulating and pain relieving.Fructus Citri Sarcodactylis: return lung, spleen channel, the energy regulating QI to relieve pain, stomach function regulating reduces phlegm, and is the treatment depression of liver-QI, the key medicine of gastral cavilty distending pain and vomiting.More than count medicine energy vital energy regualting and blood circulation-promoting, mediator's bromhidrosis blood circulation strengthens ministerial drug and removes virus, improves curative effect, so be this medicine adjuvant drug.The Radix Astragali: return lung, spleen channel, invigorating QI to consolidate the body surface resistance, diuresis, expelling pus and toxin by strengthening QI, granulation promoting can be held under the arm just eliminating evilly, strengthen human organism's metabolism, improve immunologic function, are the key medicines that reduces glutamate pyruvate transaminase.Radix Codonopsis: return spleen, lung meridian, tonification gas can be treated the Liver and kidney QI and blood deficiency.Fructus Lycii: return liver, kidney channel, energy nourishing the liver and kidney, replenishing vital essence to improve eyesight.Fructus Ligustri Lucidi: return liver, kidney channel, can take a tonic or nourishing food to build up one's health Liver and kidney, make eye bright.The Rhizoma Atractylodis Macrocephalae: return spleen, kidney channel, can spleen reinforcing stomach reinforcing, dampness and in.Poria: GUIXIN, spleen, kidney channel, energy promoting diuresis to eliminate damp pathogen, spleen-benefiting mind-tranquilizing.Fructus Crataegi: return spleen, stomach, Liver Channel, the energy promoting digestion and removing stagnation, dissipating blood stasis is capable to stagnate.Massa Medicata Fermentata: return spleen, stomach warp, stomach function regulating can help digestion.Radix Glycyrrhizae: sweet in the mouth is flat, GUIXIN, lung, spleen, stomach warp, can invigorating the spleen and replenishing QI, and heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the mediation property of medicine can be separated medicine again, food and interior metabolism product toxicity.More than counting medicine can invigorating the liver and kidney, strengthening the spleen and stomach, aid digestion, inducing diuresis to remove edema, diuresis toxin expelling, strengthens human body constitution, helps minister, adjuvant drug antiviral, so be the messenger drug of this medicine.
Clinical verification: this Drug therapy hepatitis A curative effect reaches more than 98%, is a good basic prescription medicine of the concurrent hepatitis A disease of treatment hepatitis B.In therapeutic process, disappear as jaundice, can remove Artemisia anethoicles Mattf, Rhizoma Polygoni Cuspidati, no constipation can be removed Radix Et Rhizoma Rhei.Four flavor QI regulating medicine (Radix Aristolochiae, Rhizoma Cyperi, Fructus Citri Sarcodactylis, Cortex Magnoliae Officinalis) are selected two flavors for use, or change in turn, and five tastes blood circulation and stasis-eliminating medicine can be selected three flavors for use, or change in turn, look state of an illness pathological changes in a word and add to simplify to cut out and use the prescription medicine.
In the Clinical Laboratory of treatment hepatitis B, the concurrent hepatitis A of this Drug therapy hepatitis B, acute icteric, acute non-icteric type, strongly fragrant gallbladder type, chronic persisting type and chronic active hepatitis all have better curative effect, took medicine for the first time 3-5 month, examination of serum, two positive patients of hepatitis B B antibody and hepatitis B core antibody have 50% can turn out cloudy by sun, 1-2 month liver function of taking medicine is normal, can continue and take the application of this prescription medicine plus-minus, chemical examination in three months, can turn out cloudy hepatitis B surface antigen entirely, three small three positive patients of B antibody and core antibody, the chemical examination in three months of taking medicine for the first time, hepatitis B B antibody or hepatitis B core antibody can have 30% patient wherein a positive can turn out cloudy, liver function is normal.The positive ratio unit of the project of not turning out cloudy (s/n) can reduce to half, and this prescription of clothes medicine plus-minus application of treatment can continue.Hepatitis B surface antigen, three great three positive patients of hepatitis B B antigen and core antibody, the chemical examination in three months of taking medicine for the first time, ratio unit can reduce to half, liver function is normal, the chemical examination in 3 months of taking medicine continues, can transfer hepatitis B surface antigen to, three small three positive of B antibody and core antibody, positive project ratio unit (s/n) can reduce to half, the chemical examination in 3 months of taking medicine that continues, and small three positive wherein has hepatitis B B antibody or hepatitis B core antibody to turn out cloudy by sun, do not turn out cloudy and positive project ratio unit can reduce to half again, the medication treatment that continues can reach the positive and turn out cloudy entirely.
Treatment hepatitis B complication of the present invention is applicable in the medicine of the disease for the treatment of the concurrent liver cirrhosis of hepatitis B: Squama Manis: go into liver, stomach warp, and the energy dispersing swelling and dissipating binds, promoting blood circulation to remove obstruction in the collateral again can the treating the liver splenomegaly.Rhizoma sparganic: return liver, spleen channel, energy removing blood stasis, promoting the circulation of QI to relieve pain eliminating stagnation.Rhizoma Curcumae: return liver, spleen channel, energy removing blood stasis, removing food stagnancy, promoting the circulation of QI to relieve pain eliminating stagnation.Carapax Trionycis: go into the liver,spleen,kidney warp, energy nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving.The four medicines liver spleen channel of going directly is so treatment hepatosplenomegaly and scleroma show curative effect.Pink: GUIXIN, liver, large intestine channel, energy blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.Flos Carthami: GUIXIN, Liver Channel, energy blood circulation promoting and blood stasis dispelling, dredge the meridian passage.Flos Carthami, pink two medicines can help rhizoma sparganic, Rhizoma Curcumae, the hard stagnation of blood stasis of Squama Manis treating the liver to cause the disease of scleroma, help Carapax Trionycis to improve the merit of hard masses softening and resolving.Herba Dendrobii: return lung, stomach, kidney channel, energy yin nourishing stomach reinforcing, promoting the production of body fluid to quench thirst.Radix Glehniae: attach to the lung and stomach meridians, the energy nourishing YIN and moistening the lung, lung benefiting promotes the production of body fluid.Radix Ophiopogonis: GUIXIN, lung, stomach warp, energy yin nourishing stomach reinforcing, the profit stomach clears away heart-fire.Radix Asparagi: return lung, kidney channel, energy lung heat clearing pathogenic fire reducing is nourshing Yin and drynsessmoistening prescription.Herba Dendrobii, Radix Glehniae, Radix Ophiopogonis, Radix Asparagi four medicine function clearing away heart-fire and moistening the lung, reinforcing stomach reg fluid is with the softening liver of Carapax Trionycis YIN nourishing.Lung (gold) is given birth to kidney (water), and the living liver of kidney (water) (wood), respectful the falling of lung (gold) gas can be helped kidney (water).Kidney belongs to water, the liver belonging to wood, but the essence nourishing the liver wood of kidney water, and blood stored in the liver, kidney storing essence smart can be given birth to marrow, marrow energy hemopoietic, deficiency of kidney yin then liver blood also loses, and liver-yang is to lean on the culvert of the kidney yin unlikely rising of cultivating people of ability, so Liver and kidney " saying of homology " is arranged.The ruling by law of utilization replenishing the kidney(water)to nourish the liver(wood) is treated liver cirrhosis and is had curative effect preferably.Reinforcing stomach reg fluid, the change of body fluid comes from water paddy from birth, and after being digested and assimilated by taste, the gasification through three warmers forms respectively again.One liver of supplementing nutrition of moistening, two water liquid in can supplemental blood.Can alleviate febrile conditions.Though the through Liver Channel of event Herba Dendrobii, Radix Glehniae, Radix Ophiopogonis, Radix Asparagi four medicines can moisten liver, the Ji heart-fire, softening hepar induratum joint so use building up the spleen to supplement the lung, is strengthened the method for water system fire, can receive curative effect preferably.
Liver cirrhosis is a kind of more common chronic disease, and hepatocellular damage appears in whole liver, the liver proliferation of fibrous tissue, and hepatocyte forms pathological changes such as existing regenerated nodule, has destroyed the normal liver tissue structure, makes liver distortion and hardening.The kind of liver cirrhosis is classified by pathomorphism: can be divided into portal cirrhosis, gangrenosum acne liver cirrhosis, biliary cirrhosis.Classify by the cause of disease: can be divided into posthepatitic cirrhosis, schistosomal cirrhosis, alcoholic cirrhosis, biliary cirrhosis, circulatory disturbance liver cirrhosis, dysbolismus liver cirrhosis, except that the liver cirrhosis of schistosomicide appearance in late period, do not prove and belong to what type, the essence of pathological changes is identical in its liver, thereby the main formula of treatment liver cirrhosis can be constant, but must cut out utilization with card plus-minus, flexibility.The clinical manifestation symptom is obvious, and patient with liver cirrhosis can occur that abdominal distention, stomachache, diarrhoea and constipation replace, generate heat, become thin, cutaneous pigmentation, jaundice occurs from head to foot.Spider angioma sees cervical region, face, forearm, the back of the hand and breast top, and erythema appears in the big thenar of palm, hypothenar, and liver sclerosis tuberosity can be laid one's hand on and be arrived to the right side of body.
Nearly 3 years through clinical treatment 9 routine disease analysis of control tables:
The preceding laboratory test report of taking medicine
Name | Sex | Age | HBSAg | HBeAg | HBCAb | Jaundice | Sclerosis | Hepatosplenomegaly | Tongue | Tongue | Arteries and veins |
Bears * | The woman | 36 | Sun | Sun | Sun | Have | Have | Have | Red | Yellow | Stringy and rapid pulse |
Lee * | The man | 43 | Sun | Sun | Sun | Have | Have | Have | Red | Yellow | Stringy and rapid pulse |
Gold * | The man | 48 | Sun | Sun | Sun | Have | Have | Have | Red red | Yellow | Stringy and tense pulse |
Sieve * | The woman | 49 | Sun | Sun | Sun | Have | Have | Have | Purple dark | Do not have | Loud |
Old * | The woman | 39 | Sun | Sun | Sun | Have | Have | Have | Red | Yellow | Number |
The king * | The man | 50 | Sun | Sun | Sun | Have | Have | Have | Purple dark | Do not have | Loud |
The week * | The man | 29 | Sun | Sun | Sun | Have | Have | Have | Red | Yellow | Puckery |
Slowly * | The woman | 33 | Sun | Sun | Sun | Have | Have | Have | Red | Yellow | Number |
The Wei * | The woman | 45 | Sun | Sun | Sun | Have | Have | Have | Red | Yellow | Loud |
Laboratory test report after taking medicine
Name | Sex | Age | ??HBSAg | ??HBeAg | ??HBCAb | Sn unit | Jaundice | Sclerosis | Hepatosplenomegaly | Tongue | Tongue | Arteries and veins |
Bears * | The woman | ??36 | Cloudy | Cloudy | Cloudy | Do not have | Do not have | Do not have | Light | In vain | Normally | |
Lee * | The man | ??43 | Sun | Cloudy | Cloudy | ??5>1 | Do not have | Do not have | Do not have | Light | In vain | Normally |
Gold * | The man | ??48 | Sun | Cloudy | Cloudy | ??10>1 | Do not have | Do not have | Do not have | Light | In vain | Normally |
Sieve * | The woman | ??49 | Sun | Cloudy | Cloudy | ??9>1 | Do not have | Do not have | Do not have | Light | In vain | Normally |
Old * | The woman | ??39 | Cloudy | Cloudy | Cloudy | Do not have | Do not have | Do not have | Light | In vain | Normally | |
The king * | The man | ??50 | Sun | Cloudy | Cloudy | ??11>1 | Do not have | Do not have | Do not have | Light | In vain | Normally |
The week * | The man | ??29 | Cloudy | Cloudy | Cloudy | Do not have | Do not have | Do not have | Light | In vain | Normally | |
Slowly * | The woman | ??33 | Cloudy | Cloudy | Cloudy | Do not have | Do not have | Do not have | Light | In vain | Normally | |
The Wei * | The woman | ??45 | Sun | Cloudy | Cloudy | ??6>1 | Do not have | Do not have | Do not have | Light | In vain | Normally |
More than 9 routine patients all belong to the serious symptom hepatitis B, take our medicine plus-minus and use, through treating 2 months, jaundice, hepatosplenomegaly and scleroma can disappear, and continue and take medicine 6 months, do not have sclerosis, liver function test is normal.Remove our prescription medicine, the aforementioned basic Drug therapy of clothes that continues 9 months has 4 routine surface antigens, and B antigen and core antibody are turned out cloudy.There are 5 routine B antigens and core antibody to turn out cloudy, a surface antigen (HBSAg) positive, ratio unit (Sn unit) is respectively 5>1,6>1,9>1,10>1,11>1, the 5 routine surface antigens patient that do not turn out cloudy wherein, but body constitution recovers normal, can work, work, not medication treatment again.
Treatment hepatitis B complication of the present invention is applicable in the medicine of the concurrent cirrhotic ascites disease of treatment hepatitis B: Pericarpium Arecae: return spleen, stomach, large intestine, small intestine meridian, energy promoting the circulation of QI to alleviate the stagnation in middle-JIAO, inducing diuresis to remove edema.Semen Pharbitidis: return lung, kidney, large intestine channel, the energy removing water retention by purgation removes long-pending parasite killing, makes water wet from two just eliminatings.Semen Plantaginis: return lung, bladder, small intestinal, kidney, Liver Channel, energy relieving stranguria by diuresis, clearing away heat to improve acuity of vision.Caulis Akebiae: GUIXIN, small intestinal, urinary bladder channel, can clearing away heat and promoting diuresis.
Cirrhotic ascites, clinical manifestation are the hepatic fibrosis hypertrophy, become the lump tuberosity, the hepatocyte grievous injury, late period liver become homeless moisten support cause liver change downright bad, water liquid dysbolismus from head to foot, abdominal part distension such as swollen shape, as frog abdomen, the critically ill patient high fever.
Nearly 3 years clinical treatment 6 routine disease analysis of control tables:
The preceding laboratory test report of taking medicine:
Name | Sex | Age | HBSAg | HBeAg | HBCAb | Jaundice | Sclerosis | Hepatosplenomegaly | Tongue | Tongue | Arteries and veins |
Lee- | The man | 26 | Sun | Sun | Sun | Have | Have | Have | Red | Yellow | Number |
Wear- | The man | 36 | Sun | Sun | Sun | Have | Have | Have | Livid purple | Yellow | Stringy and rapid pulse |
Slowly- | The woman | 37 | Sun | Sun | Sun | Have | Have | Have | Purple | Do not have | Tight number |
Old- | The woman | 29 | Sun | Sun | Sun | Have | Have | Have | Purple | Do not have | Tight number |
Sieve- | The woman | 32 | Sun | Sun | Sun | Have | Have | Have | Purple dark | Do not have | Tight number |
Ten thousand- | The man | 28 | Sun | Sun | Sun | Have | Have | Have | Red | Yellow | Number |
Laboratory test report after taking medicine:
Name | Sex | Age | HBSAg | HBeAg | HBCAb | S/n unit | Jaundice | Sclerosis | Hepatosplenomegaly | Tongue | Tongue | Arteries and veins |
Lee- | The man | 26 | Cloudy | Cloudy | Cloudy | Have | Have | Have | Light red | In vain | Normally | |
Wear- | The man | 36 | Sun | Cloudy | Cloudy | 8>1 | Have | Have | Have | Light red | In vain | Normally |
Slowly- | The woman | 37 | Sun | Cloudy | Cloudy | 10>1 | Have | Have | Have | Light red | In vain | Normally |
Old- | The woman | 29 | Cloudy | Cloudy | Cloudy | Have | Have | Have | Light red | In vain | Normally | |
Sieve- | The woman | 32 | Sun | Cloudy | Cloudy | 7>1 | Have | Have | Have | Light red | In vain | Normally |
Ten thousand- | The man | 28 | Cloudy | Cloudy | Cloudy | Have | Have | Have | Light red | In vain | Normally |
6 routine patients were through medication treatment one month, and ascites, jaundice disappear, and the state of an illness is alleviated, the medicine of the disease of the concurrent liver cirrhosis of the above-mentioned treatment hepatitis B of clothes that continues, and treatment half a year, liver function is normal, no liver cirrhosis.The basic medicine plus-minus of the clothes that continue is used, 9 months, the hepatitis B examination of serum had 3 routine surface antigens, and B antigen and three positives of core Hangzhoupro body are turned out cloudy, there are 3 routine B antigens and core antibody positive to turn out cloudy, hepatitis B surface antigen (HBSAg) positive, ratio unit (Sn unit) is respectively 7>1,8>1,10>1, and tongue fur is light white, pulse is normal, can work as usual, work is not received treatment again.
Treatment hepatitis B complication of the present invention is applicable in the medicine of treatment hepatitis B and seminal emission: Radix Polygalae: return lung, heart channel, the energy mind tranquilizing and the heart calming eliminates the phlegm and has one's ideas straightened out, and the pain that disappears is swollen.Semen Ziziphi Spinosae: GUIXIN, liver, large intestine channel, energy tranquilizing by nourishing the heart, loosening bowel to relieve constipation.Arillus Longan: GUIXIN, spleen channel, reinforcing the heart spleen, replenishing QI and blood.Fructus Corni: return liver, kidney channel, energy liver and kidney tonifying, arresting seminal emission arresting sweating.Herba Cistanches: return kidney, large intestine channel, energy the kidney invigorating and essence nourishing, loosening bowel to relieve constipation.Semen Cuscutae: return liver, kidney channel, can invigorating the liver and kidney benefit essence.Semen Astragali Complanati: return liver, kidney channel, can the tonifying the kidney to consolidate the essence nourishing the liver.Fructus Schisandrae Chinensis: return lung, kidney channel, can restrain astringent or styptic treatment for spontaneous sweatingly, supplementing QI for promoting the production of body fluid, the kidney invigorating are supported smart.
Through clinical treatment 4 routine disease analyses:
Lee--, man 36 years old, ill 6 years.Old-, man 30 years old, ill 6 years.Dong-, man 33 years old, ill 5 years.Money-, man 48 years old, ill 3 years.More than 4 routine diseases identical, hepatitis B surface antigen, B antigen and three positives of core antibody, sick time, there is gap at the age, can rule together with disease.The patient tells and falls ill for many years, treats through doctor, expert in each big infirmary, and curative effect is always incapable.In therapeutic process, a very important person has a few spirit, and the state of an illness gradually take a favorable turn, and does nocturnal emission suddenly evening, and dizzy dusk is tired from head to foot, thirsty later, and the waist soft acid is bloated, abdominal distention, and the right side of body has painful sense, and brothers are unable, and mouth is tasteless, loss of appetite.Have a medical check-up: no jaundice, liver does not have sclerosis, the enlargement slightly of liver spleen, face is dark violet, and is uncomfortable in chest, and the right side of body has painful sense, hard stool, yellow urine, red tongue, yellow fur, stringy and tense pulse is through the no hepatocarcinoma of chemical examination.Dialectical: liver (wood) is lit a fire, and kidney (water) is given birth to wood, the liver belonging to wood, and the heart matches fire, kidney belongs to water.Heart governing blood and vessels master mind; Blood stored in the liver, main vegetables let out; Hepatic lesions makes the blood of liver (wood) the heart (fire) that can not help cause the heart not keep god, so dreaminess.Incessantly overflowing of kidney water carried in the fortune imbalance of spleen (soil), makes the essence of kidney water can not edema with the liver involved, so pass out semen, suffering from a deficiency of the kidney, then liver (wood) is withered.So use base furnish for square substantially in this disease event of treatment, the reinforcing the heart of being nourished heart, tonifying speen and tonifying kidney and restrain astringent or styptic treatment for spontaneous sweating medicine and just can receive curative effect is preferably used this Drug therapy, patient's two weeks of taking medicine, curative effect shows, 2 months liver spleens of taking medicine swell slightly and disappear, and the hepatic region is painful, and brothers are not soft, there is not abdominal distention uncomfortable in chest, not seminal emission.The chemical examination in three months of taking medicine that continues, liver function is normal, and the clothes hepatitis B that continues basis medicine 14 months has 3 routine patient's hepatitis B surface antigens, and three positives of B antigen and core antibody are turned out cloudy, and get well.
Treatment hepatitis B complication prescription medicine treatment hepatitis B of the present invention and complication have no side effect, but strengthening vital QI to eliminate pathogenic factors helps the rehabilitation of liver, each prescription medicine all is respectively at disease, pathological changes, and with cold and heat, deficiency and excess adds to simplify cuts out diagnosis and prescription, but hepatoprotective, good drug efficacy, antiviral is strong.Through treatment hepatitis B and clinical 50 examples of hepatitis B complication: wherein 20-30 year 15 examples, 31-50 year 35 examples, male 27 examples, women 23 examples, hepatitis B 11 examples, concurrent hepatitis A 20 examples of hepatitis B, concurrent liver cirrhosis 9 examples of hepatitis B, concurrent cirrhotic ascites 6 examples of hepatitis B, concurrent seminal emission 4 examples of hepatitis B, total effective in curely reach 98%, cure rate reaches 88-90%, and three positive patients of hepatitis B B antibody and core antibody are taken medicine and can be turned out cloudy by sun in 4-9 month; Hepatitis B surface antigen, three positive patients of B antibody and core antibody are taken medicine and can be turned out cloudy by sun in 15 months-2 years; Wherein have 8 routine hepatitis B surface antigen (HBSAG) positives to fail to pass on the moon, but patient's body constitution recovers normal, the work of working is without treatment again.
The specific embodiment
Embodiment 1:
A kind of treatment hepatitis B complication is applicable to that treating the concurrent hepatitis A of hepatitis B does not have ascites, the medicine of no liver cirrhosis disease is to be made by following weight portion crude drug: Radix Bupleuri 15, the Radix Paeoniae Alba 20, Radix Curcumae 10, Herba Artemisiae Scopariae 30, Rhizoma Bistortae 15, Flos Chrysanthemi Indici 15, Herba Sedi 30, Herba Hedyotidis Diffusae 30, Herba Scutellariae Barbatae 30, Rhizoma Paridis 20, Flos Lonicerae 15, Radix Isatidis 30, Rhizoma Polygoni Cuspidati 20, Radix Et Rhizoma Rhei 10, Radix Angelicae Sinensis 15, Radix Salviae Miltiorrhizae 20, Radix Paeoniae Rubra 10, the Radix Rehmanniae 15, Radix Polygoni Multiflori 30, Radix Aristolochiae 10, Cortex Magnoliae Officinalis 15, Rhizoma Cyperi 15, Fructus Citri Sarcodactylis 10, the Radix Astragali 50, Radix Codonopsis 15, Fructus Lycii 25, Fructus Ligustri Lucidi 30, the Rhizoma Atractylodis Macrocephalae 15, Poria 20, Fructus Crataegi 30, Massa Medicata Fermentata 20, Radix Glycyrrhizae 10.
Its preparation method is: 1, the each component raw material powder is broken into 100 orders; 2, the component raw material mix homogeneously after will pulverizing again; 3, make powder by the 150 gram packs of every bag of content of dispersion.
Embodiment 2:
A kind of hepatitis B complication for the treatment of is applicable to that the medicine of the concurrent seminal emission disease of treatment hepatitis B is to be made by following weight portion crude drug: Radix Bupleuri 15, the Radix Paeoniae Alba 40, Radix Curcumae 10, Herba Artemisiae Scopariae 30, Rhizoma Bistortae 15, Flos Chrysanthemi Indici 15, Herba Sedi 30, Herba Hedyotidis Diffusae 30, Herba Scutellariae Barbatae 30, Rhizoma Paridis 20, Flos Lonicerae 15, Radix Isatidis 30, Rhizoma Polygoni Cuspidati 20, Radix Et Rhizoma Rhei 10, Radix Angelicae Sinensis 15, Radix Salviae Miltiorrhizae 20, Radix Paeoniae Rubra 15, the Radix Rehmanniae 15, Radix Polygoni Multiflori 15, Radix Aristolochiae 10, Cortex Magnoliae Officinalis 15, Rhizoma Cyperi 15, Fructus Citri Sarcodactylis 10, the Radix Astragali 50, Radix Codonopsis 20, Fructus Lycii 25, Fructus Ligustri Lucidi 30, the Rhizoma Atractylodis Macrocephalae 15, Poria 20, Fructus Crataegi 30, Massa Medicata Fermentata 20, Radix Glycyrrhizae 10, Radix Polygalae 15, Semen Ziziphi Spinosae 20, Semen Platycladi 20, Arillus Longan 30, Fructus Corni 20, Herba Cistanches 15, Semen Cuscutae 20, Semen Astragali Complanati 10, Fructus Schisandrae Chinensis 20.
Its preparation method is identical with embodiment 1.
Embodiment 3:
A kind of hepatitis B complication for the treatment of is applicable to that the medicine of the concurrent liver cirrhosis disease of treatment hepatitis B is to be made by following weight portion crude drug: Radix Bupleuri 15, BAIYAO 40, Radix Curcumae 10, Herba Artemisiae Scopariae 30, Rhizoma Bistortae 15, Flos Chrysanthemi Indici 15, Herba Sedi 30, Herba Hedyotidis Diffusae 30, Herba Scutellariae Barbatae 30, Rhizoma Paridis 20, Flos Lonicerae 15, Radix Isatidis 30, Rhizoma Polygoni Cuspidati 20, Radix Et Rhizoma Rhei 20, Radix Angelicae Sinensis 15, Radix Salviae Miltiorrhizae 20, Radix Paeoniae Rubra 15, the Radix Rehmanniae 15, Radix Polygoni Multiflori 20, Radix Aristolochiae 10, Cortex Magnoliae Officinalis 15, Rhizoma Cyperi 15, Fructus Citri Sarcodactylis 10, the Radix Astragali 60, Radix Codonopsis 30, Fructus Lycii 25, Fructus Ligustri Lucidi 20, the Rhizoma Atractylodis Macrocephalae 15, Poria 20, Fructus Crataegi 30, Massa Medicata Fermentata 10, Radix Glycyrrhizae 10, Squama Manis 15, rhizoma sparganic 10, Rhizoma Curcumae 10, Flos Carthami 8, Carapax Trionycis 60, Herba Dendrobii 30, Radix Glehniae 50, Radix Asparagi 50, Radix Ophiopogonis 30.
Its preparation method is identical with embodiment 1.
Embodiment 4:
A kind of hepatitis B complication for the treatment of is applicable to that the medicine of the concurrent cirrhotic ascites of treatment hepatitis B is to be made by following weight portion crude drug: Radix Bupleuri 15, the Radix Paeoniae Alba 40, Radix Curcumae 10, Herba Artemisiae Scopariae 30, Rhizoma Bistortae 15, Flos Chrysanthemi Indici 15, Herba Sedi 30, Herba Hedyotidis Diffusae 30, Herba Scutellariae Barbatae 30, Rhizoma Paridis 20, Flos Lonicerae 15, Radix Isatidis 30, Rhizoma Polygoni Cuspidati 20, Radix Et Rhizoma Rhei 30, Radix Angelicae Sinensis 15, Radix Salviae Miltiorrhizae 20, Radix Paeoniae Rubra 15, Radix Salviae Miltiorrhizae 20, the Radix Rehmanniae 15, Radix Polygoni Multiflori 30, Radix Aristolochiae 10, Cortex Magnoliae Officinalis 15, Rhizoma Cyperi 15, Fructus Citri Sarcodactylis 10, the Radix Astragali 90, Radix Codonopsis 30, Fructus Lycii 25, Fructus Ligustri Lucidi 30, the Rhizoma Atractylodis Macrocephalae 15, Poria 90, Fructus Crataegi 30, Massa Medicata Fermentata 10, Radix Glycyrrhizae 10, Squama Manis 20, rhizoma sparganic 10, Rhizoma Curcumae 10, pink 10, Flos Carthami 8, Carapax Trionycis 60, Herba Dendrobii 30, Radix Glehniae 50, Radix Asparagi 50, Radix Ophiopogonis 30, Pericarpium Arecae 20, Semen Pharbitidis 20, Semen Plantaginis 30, Caulis Akebiae 15.
Its preparation method is identical with embodiment 1.
Claims (4)
1, a kind of hepatitis B complication prescription medicine for the treatment of, it is characterized in that: it is to be made by following weight portion bulk drug: radix bupleuri 15 root of herbaceous peony 20-40 root tubers of aromatic turmeric 10 oriental wormwoods 30 adder-worts 15 mother chrysanthemums 15 stringy stonecrops 30 oldenlandia diffusas 30 Herba Scutellariae Barbataes 30 Paris polyphylla 20 honeysuckle flowers 15 isatis roots 30 giant knotweeds 20 rheum officinale 10-30 Radix Angelicae Sinensis 15 red sage root 10-20 radix paeoniae rubrathe 10-15 dried rhizome of rehmannia 15 fleece-flower root 15-30 dutchmanspipe roots 10 barks of official magnolia 15 rhizoma cyperis 15 Buddha's hands 10 Radix Astragali 30-90 Radix Codonopsis 15-30 fruits of Chinese wolfberry 25 fruit of glossy privet 15-30 bighead atractylodes rhizomes 15 Poria cocos 20-90 hawthorn 30 Divine Comedy 10-20 Radix Glycyrrhizae 6-10.
2, treatment hepatitis B complication prescription medicine according to claim 1 is characterized in that: also comprise Radix Polygalae 15, Semen Ziziphi Spinosae 20, Semen Platycladi 20, Arillus Longan 30, Fructus Corni 20, Herba Cistanches 15, Semen Cuscutae 20, Semen Astragali Complanati 10, Fructus Schisandrae Chinensis 20 in the component raw material.
3, treatment hepatitis B complication prescription medicine according to claim 1 is characterized in that: also comprise Squama Manis 15-20, rhizoma sparganic 10, Rhizoma Curcumae 10, pink 10, Flos Carthami 8, Carapax Trionycis 60, Herba Dendrobii 30, Radix Adenophorae (Radix Glehniae) 30-50, Radix Ophiopogonis 30-50, Radix Asparagi 30-50 in the component raw material.
4, treatment hepatitis B complication prescription medicine according to claim 3 is characterized in that: also comprise Pericarpium Arecae 20, Semen Pharbitidis 20, Semen Plantaginis 30, Caulis Akebiae 15 in the component raw material.
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