CN103751707B - Oral liquid of a kind of great burdock achene beauty treatment and eliminating spot and preparation method thereof - Google Patents

Oral liquid of a kind of great burdock achene beauty treatment and eliminating spot and preparation method thereof Download PDF

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CN103751707B
CN103751707B CN201310749449.3A CN201310749449A CN103751707B CN 103751707 B CN103751707 B CN 103751707B CN 201310749449 A CN201310749449 A CN 201310749449A CN 103751707 B CN103751707 B CN 103751707B
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great burdock
burdock achene
beauty treatment
oral liquid
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CN103751707A (en
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不公告发明人
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Guangzhou Hong Sen Biotechnology Co., Ltd.
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赵玉妹
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Abstract

The invention discloses a kind of great burdock achene beauty treatment and eliminating spot oral liquid and preparation method thereof, in described great burdock achene beauty treatment and eliminating spot oral liquid, the parts by weight of various raw materials are: 10～50 parts of great burdock achenes, 10～20 parts of radix polygonati officinalis, 10～20 parts of dragon's blood, 10～20 parts of Radix Angelicae Sinensis, 10～20 parts of pseudo-ginseng, 10～20 parts of bletillas, 10～20 parts, Poria cocos, 10～20 parts of the reds sage root, 10～20 parts of raspberries, 10～20 parts of dessert almonds, 10～20 parts of the root barks of white mulberry, 10～20 parts of sealworts, 10～20 parts of root tubers of aromatic turmeric, 10～20 parts of rhizoma cyperis, 10～20 parts of the Radixs Astragali, 10～20 parts of heart of a lotus seed benevolence, 10～20 parts of the bighead atractylodes rhizomes, 10～20 parts of Flos Albiziaes, 10～20 parts of motherworts, 10～20 parts of reticulate millettias, 10～20 parts of the larva of a silkworm with batrytis, 10～20 parts of the fruit of glossy privets, 10～20 parts of the roots of Dahurain angelica, 10～20 parts of kaladanas. can reach the effect that beautifies skin.

Description

Oral liquid of a kind of great burdock achene beauty treatment and eliminating spot and preparation method thereof
Technical field
The present invention relates to contain the health products that derive from plant, animal or mineral component, particularly a kind of great burdock achene U.S.Hold oral liquid of nti-freckle and preparation method thereof.
Background technology
The chloasma traditional Chinese medical science is called " chloasma hepaticum ", belongs to motherland's medical science " dark spot " or " dusty complexion " category. It is generally acknowledged that this disease occursDirty in close relations with liver,spleen,kidney three.
Theory of traditional Chinese medical science is thought " lung governing skin and hair ", as " Plain Questions " six joint state of internal organs opinion clouds: lung person, the dominator of QI, the position of storing soul also, its ChinaAt hair, it fills at skin, points out that lung closes fur at body. When the function of lung is normal, lung yin is full, and normal lung-QI is peaceful, body fluid abundance, abilityCompress must be capable, and skin metabolism product is excreted, and makes skin cleaning, naturally shines gloss. Therefore have from ancient times to the present manyDoctor, recipe have from lung opinion to be controlled. Chloasma, chloasma hepaticum are a kind of facial metabolism of pigment obstacle dermatosis that is common in, goodSend out in female middle-aged, its cause of disease and pathogenesis are illustrated not yet completely. It is generally acknowledged morbidity and the endocrinopathy of chloasma, purpleOutside line is irradiated, and inherent cause is relevant. But research in recent years thinks, the generation of chloasma, chloasma hepaticum also changes relevant with oxygen radical.In normal physiological situation, free radical constantly produces, but is also constantly eliminated, and makes it in a kind of dynamic equilibrium. And chloasma,When chloasma hepaticum patient lipid peroxide (LPO) or Free Radical Level increase, or in body, antioxidase is as superoxide dismutase(SOD), the decline such as catalase (CAT), glutathione (CSH), can not remove in time the oxidation products such as lipid peroxide, makeLPO piles up in vivo. Thereby accelerate tyrosine series oxidation reaction. Blackening chromatophore produces melanin to be increased; The LPO utmost point simultaneouslyIt is crosslinked that unstable its product MDA (MDA) can cause protein molecule to occur, and forms fluorescent chromophore-pigment.
Chloasma, chloasma hepaticum are the diseases that long-term factors causes. The activity of skin tyrosinase declines, and melanin is thinEndosome quantity increases, and wherein oxygen radical is one of major reason of chloasma formation. Most important in body antioxidant systemBe the effect of antioxidase, wherein SOD is one of topmost enzyme.
Modern people's living and diet is too meticulous, and amount of exercise reduces, or eats and drinks immoderately, or overstrain, makes human bodyMetabolism fails gradually, causes visceral dysfunction, easily causes the pigmented lesion such as chloasma faciei, freckle. InDoctor thinks, facial colour spot is uncomfortable because of internal organs meridian qi and blood, and the deficiency of blood is not dissolved in face; Or because of inernal injuries caused by seven emotions, stagnation of QI due to depression of the liver, liver spleen is notWith; Or because of improper diet and overtiredness, irregular menstruation; Or because of the blood system of the strongly fragrant channels and collaterals of fire, ailment said due to cold or exposure is rich and due to sending out outward. Adopt this class of western medicineMostly disease, be outer wiping or vitamins for oral administration, flavonols medicine. Because pathogenesis is more, adopt western medicine effect notOne, be also difficult for radical cure, some medicine side effect is larger.
Great burdock achene has another name called Great Burdock Achene, FRUCTUS ARCTII, is the fruit of feverfew burdock, and annual 8～September is when fruit maturation,Gather in batches, after drying, get fruit, remove impurity, then shine to absolutely dry can being used as medicine. It is cool in nature, and taste is arduous, enters lung, stomach warp,There is effect of dispelling wind and heat from the body, a surname's lung promoting eruption, subdhing swelling and detoxicating, be used for the treatment of cough due to wind-heat evil, abscess of throat, macula not thoroughly, rubellaHave an itch, the disease such as carbuncle sore tumefacting virus, be the key medicine of loose wind except thermal detoxification. On market, have with the fruit of equal plant thistle and pretend to be certified productsGreat burdock achene, notes when use differentiating. " Bencao Jingshu ": disliking in fact, is the key medicine of loose wind except thermal detoxification. Pungent energy dissipating bind, hardship can expel the heat-evil,The loose visceral-qi of thermojunction Clear and Bright, therefore improving eyesight and bowl spares. The institute of wind hinders, defend gas and must stop up, stop up heating, Xin Liang dismiss show gas and, windNothing institute is stayed. Hide the swollen all impotences of device main air poison; The main moistening lung of element, dissipating bind gas, relieve sore throat diaphragm, peeling skin wind, logical twelve channels and collaterals person, know thisMeaning ear. Therefore in order to control urticaria, variola, especially obtain very and test. " medicine justice ": great burdock achene can rise and can fall, power relieving heat toxin. Bitter can be clearFire, is with pungent energy dispelling wind, cures mainly top wind phlegm, the edema of the face, discomfort in the throat, all scorchingly hot heap soil or fertilizer over and around the rootss, sabre scrofula, neck subcutaneous nodule, blood-headAcne, time row measles, urticaria, all lung channel stagnated fire, wind and heat in the lung meridian, knows and should use this. " book on Chinese herbal medicine is looked for the truth ": great burdock achene, moderns are speech onlyRemoving toxic substances, the diseases such as all chance sore carbuncles are swollen, acne rash, control with this throwing invariably, so still do not unravel silk its justice. The knot of ordinary person's poison gas, many edge diseases caused by external factors windCold, the stagnation of ying-qi, contrary in meat, therefore raw carbuncle poison. Burdock taste is pungent and bitter, can sending down abnormally ascending descending, and the reactivation wind heat extraction that falls apart, is to experienceAilment said due to cold or exposure heat poison and see the edema of the face, cough phlegm is stopped up, between pharynx, swells and ache, sore macula, and all smelly poison, acute diseases such as cholera and sunstroke close, variola purple is black, just closeDeng disease, invariably show whereby Xie Liqing. But the cold sliding profit of property, many clothes middle gas damage, and more order table benefit is empty. As for splenasthenic diarrhea beEspecially here avoid.
Great burdock achene has effect of catharsis and toxin expelling, be called again " clean intestines grass " among the people. Great burdock achene can also stimulate circulation, pre-Anti-cardiovascular disease, burdock extract has very strong removing free radical and antioxidation, the yellow glucoside in great burdock achene, amino acidWith the synthetic collagen Proteins of amino acid, human body is improved looks, check melanin growth, keeps skin gloss and elasticity to play not littleEffect.
The various cosmetic health products of selling on the market now, dragons and fishes jumbled together for medicine, and great majority are all businessman's amusement, do not haveAny effect, and can cause the huge injury of the person. Chinese medicine beauty treatment, fat-reducing, have nontoxic, can be absorbed completely by organismAdvantage is the main direction that we study. There are reducing blood lipid, antibacterial, hypoglycemic, antioxygen in market in the urgent need to developing one nowChange, the health products of whitening spot-removing effect, and that exploitation burdock subclass cosmetic health product is just meeting is nontoxic, can be absorbed completely by organismAdvantage, there is huge market potential.
Summary of the invention
Technical problem to be solved by this invention is, the various cosmetic health products that sell market, and dragons and fishes jumbled together for medicine, largeMajority is all businessman's amusement, without any effect, and can cause the huge injury of the person; Great burdock achene can promote that blood followsRing, prevention cardiovascular disease, burdock extract has very strong removing free radical and antioxidation, yellow glucoside in great burdock achene,The synthetic collagen Proteins of amino acid and amino acid is improved looks to human body, and check melanin growth keeps skin gloss and elasticity to riseNo small effect. The present invention is the health products of green health environmental protection completely. Add that some are promoting blood circulation and removing blood stasis, inrigorating qi and promoting blood circulation, tonifying QiRise the natural traditional Chinese medicine of sun, soothing liver-qi stagnation, calming the liver, enriching yin and nourishing kidney, clearing heat and detoxicating, clearing heat-fire, strengthening vital QI to eliminate pathogenic factors, logical internal organs is let outPoison, promoting blood circulation to remove blood stasis, the metabolic function of adjusting human body, improves blood circulation of human body and liver detoxification ability, reaches and beautifies fleshThe effect of skin.
For solving above-mentioned technical barrier, the invention provides a kind of great burdock achene beauty treatment and eliminating spot oral liquid, described great burdock achene beauty treatmentIn spot-removing oral liquid, the parts by weight of various raw materials are: 10～50 parts of great burdock achenes, and 10～20 parts of radix polygonati officinalis, 10～20 parts of dragon's blood, whenReturn 10～20 parts, 10～20 parts of pseudo-ginseng, 10～20 parts of bletillas, 10～20 parts, Poria cocos, 10～20 parts of the reds sage root, raspberry 10～20Part, 10～20 parts of dessert almonds, 10～20 parts of the root barks of white mulberry, 10～20 parts of sealworts, 10～20 parts of root tubers of aromatic turmeric, 10～20 parts of rhizoma cyperis, the Radix Astragali10～20 parts, 10～20 parts of heart of a lotus seed benevolence, 10～20 parts of the bighead atractylodes rhizomes, 10～20 parts of Flos Albiziaes, 10～20 parts of motherworts, reticulate millettia 10～20Part, 10～20 parts of the larva of a silkworm with batrytis, 10～20 parts of the fruit of glossy privets, 10～20 parts of the roots of Dahurain angelica, 10～20 parts of kaladanas.
Described great burdock achene beauty treatment and eliminating spot oral liquid, the weight portion of various raw materials in great burdock achene beauty treatment and eliminating spot oral liquid described in itNumber can be: 10～30 parts of great burdock achenes, and 10～15 parts of radix polygonati officinalis, 10～15 parts of dragon's blood, 10～15 parts of Radix Angelicae Sinensis, 10～15 parts of pseudo-ginseng,10～15 parts of bletillas, 10～15 parts, Poria cocos, 10～15 parts of the reds sage root, 10～15 parts of raspberries, 10～15 parts of dessert almonds, the root bark of white mulberry 10～15 parts, 10～20 parts of sealworts, 10～20 parts of root tubers of aromatic turmeric, 10～20 parts of rhizoma cyperis, 10～20 parts of the Radixs Astragali, 10～20 parts of heart of a lotus seed benevolence, the bighead atractylodes rhizome10～20 parts, 10～20 parts of Flos Albiziaes, 10～20 parts of motherworts, 10～20 parts of reticulate millettias, 10～20 parts of the larva of a silkworm with batrytis, the fruit of glossy privet 10～20 parts, 10～20 parts of the roots of Dahurain angelica, 10～20 parts of kaladanas.
Described great burdock achene beauty treatment and eliminating spot oral liquid, the weight portion of various raw materials in great burdock achene beauty treatment and eliminating spot oral liquid described in itNumber can also compare: 10～40 parts of great burdock achenes, 10～20 parts of radix polygonati officinalis, 10～20 parts of dragon's blood, 10～20 parts of Radix Angelicae Sinensis, pseudo-ginseng 10～20Part, 10～20 parts of bletillas, 10～20 parts, Poria cocos, 10～20 parts of the reds sage root, 10～20 parts of raspberries, 10～20 parts of dessert almonds, Sang Bai10～20 parts of skins, 10～20 parts of sealworts, 10～20 parts of root tubers of aromatic turmeric, 10～20 parts of rhizoma cyperis, 10～20 parts of the Radixs Astragali, 10～20 parts of heart of a lotus seed benevolence,10～20 parts of the bighead atractylodes rhizomes, 10～20 parts of Flos Albiziaes, 10～20 parts of motherworts, 10～20 parts of reticulate millettias, 10～20 parts of the larva of a silkworm with batrytis, glossy privet10～20 parts of sons, 10～20 parts of the roots of Dahurain angelica, 10～20 parts of kaladanas.
For solving the problems of the technologies described above, the invention provides a kind of preparation method of great burdock achene beauty treatment and eliminating spot oral liquid, its spyLevy and be, the preparation process of described great burdock achene beauty treatment and eliminating spot oral liquid comprises following aspect:
A. the frying of great burdock achene;
B. the extraction of great burdock achene;
C. described other raw materials are extracted;
D. the liquid again surplus stock being extracted is concentrated;
E. concentrated medicament is mixed with the great burdock achene extract preparing, sterilizing, adds dextrin seasoning and is prepared into oralLiquid.
In described step a, the great burdock achene of results can be cleaned, the airing time, at 7-12 hour, parches; By airingGood great burdock achene is put into the pot that completes and is gone green grass or young crops, and the 30-45 minute that completes at 80-100 DEG C, then puts into large iron pan and turn overFry, first downwards backward upper, firmly want evenly, when great burdock achene color starts blackout, start the moulding in 30-45 minute that stir-fries of little fire; WhenWhen color becomes pitchy, after taking out, naturally dry.
In described step b, may further include the good great burdock achene of frying is put into 10 times of amount ethanol, add hot reflux and carryGet 2 times, each 1～2 hour, No. 2 extracts are merged and left standstill; The great burdock achene dregs of a decoction of more above-mentioned alcohol extract being crossed add 10 times of amountsWater heating and refluxing extraction 2 times, each 1～2 hour, merges No. 2 extracts to leave standstill; Above-mentioned two kinds of extracts are merged, reclaimAfter ethanol, reducing pressure, it is concentrated to put into inspissator, and gained concentrate is adjusted to proportion to 1.06, and decompression recycling ethanol, obtains great burdock acheneExtract.
In described step c, surplus stock can be cleaned to impurity elimination, dry, be ground into particle, soak 1 hour; To soakThe raw material soaking is put boiling secondary in multi-function extractor; Add up for the first time the water of 10 times of amounts of medicinal material, decoction 1.5～2 is littleTime, get decocting liquid, filter; Add for the second time the water of 7 times of amounts of total amount, decoct 1～1.2 hour, get twice decocting liquid and mix, filter.
In described steps d, the filtrate of filtration can be inserted in economic benefits and social benefits vacuum concentrator to relative density while being concentrated into 90 DEG CBe 1.05 concentrate, set to 0～5 DEG C of deepfreezes 24 hours; Refrigeration liquid is added to 0.3% filter aid diatomite, filter filtrateInsert again in economic benefits and social benefits vacuum concentrator, be concentrated into every 1ml containing 1g crude drug amount, for subsequent use.
In described step e, great burdock achene extract can be mixed with surplus stock extract, add dextrin seasoning, ultraviolet raySterilizing, packs and get final product.
For solving the problems of the technologies described above, the present invention provides a kind of preparation method of great burdock achene beauty treatment and eliminating spot oral liquid, institute againThe preparation method who states great burdock achene beauty treatment and eliminating spot oral liquid further comprises: great burdock achene good frying and other raw materials are put into 10 timesIn water gaging, soak; Then drop into multi-function extractor and extract twice, add for the first time 8-10 times of water gaging and decoct 1-2 hour, for the second timeAdd 4-8 times of water gaging and decoct 1-2 hour, merge twice decocting liquid, filter to get filtrate; Heating is concentrated into pasty state, adds dextrin and is in harmonious proportion, ultravioletCanned after line sterilizing.
The technique effect that the present invention is useful is, that the present invention has advantages of is nontoxic, can be absorbed completely by organism. BurdockSon can stimulate circulation, and burdock extract has very strong removing free radical and antioxidation, yellow glucoside in great burdock achene,The synthetic collagen Proteins of amino acid and amino acid is improved looks to human body, and check melanin growth keeps skin gloss and elasticity to riseNo small effect. Add that some are promoting blood circulation and removing blood stasis, inrigorating qi and promoting blood circulation, tonifying Qi and lifting yang, soothing liver-qi stagnation, calming the liver, enriching yin and nourishing kidney, clearThe natural traditional Chinese medicine of thermal detoxification, clearing heat-fire, strengthening vital QI to eliminate pathogenic factors, logical internal organs is let out poison, promoting blood circulation to remove blood stasis, the metabolic function of adjusting human body,Improve blood circulation of human body and liver detoxification ability, reach the effect that beautifies skin. The present invention has retained in great burdock achene greatlyBeneficiating ingredient, make its do not have work in-process run off, on the make avoided secondary pollution, be the guarantor of green health environmental protection completelyStrong product. Energy promoting blood circulation to remove blood stasis, the metabolic function of adjusting human body, improves blood circulation of human body and liver detoxification ability, reaches beautifulChange the effect of skin.
Detailed description of the invention
Chinese medical discrimination is thought the facial colour spot such as chloasma, chloasma hepaticum or because stagnation of liver qi causes blood tired stagnant in face, or because ofThe deficiency of liver-yin and kidney-yin, flaring up of deficient fire pent-up is loose causing not. Great burdock achene beauty treatment and eliminating spot oral liquid is to chloasma, liver according to motherland's medical scienceThe facial colour spot such as spot, butterfly macules, complexion is simple and unadorned, defaecation and diagnosis and treatment and the pure traditional Chinese medicine oral liquid of one developed, the red sage root in side,Radix Angelicae Sinensis has that the paralysis that nourishes blood, invigorates blood circulation, dispels is raw new, the merit of filling liver kidney, beneficial smart bone; Matrimony vine, sealwort, the root of herbaceous peony, the red sage root tonify the liver and kidney respectively,Enrich blood invigorate blood circulation, the effect such as menstruction regulating and pain relieving, great burdock achene removing heat from blood, clearind deficient heat, defaecation dredging collateral, fruit of glossy privet filling liver kidney, the network that stimulates the menstrual flow, draw bloodDescending, make heresy have outlet. The pathology of full policy to the deficiency of liver-yin and kidney-yin, stagnation of the circulation of vital energy blood addiction, nourishing is harmonious with dredging, mends and without the stagnant qi and blood of honeyFraud, be suitable for informal dress, and receive the nti-freckle merit of preserving youthful looks.
" book on Chinese herbal medicine justice ": the use of burdock, energy dispelling wind and heat from the body, rises and sends out an acne rash, and kind logical stool, Gou Feire contains, or temper is notSolid person, that throws often has loose bowels, and the pungent hardship of letting out is fallen, and descending power is many. The clean ancient temperature of doing, Jing Yue calls again it has liter in falling, all non-True essence. " not Lu " claims its improving eyesight, and wind-heat is let out and order is self-evident. Bowl spares person, also Xing's heat is gone and is just certainly pacified. Except wind the wounded, with wind-heatSpeech also. Its rhizome, is on the point of the bitter cold of lake " detailed outline " meaning, and " not Lu " cures mainly all meanings of heat extraction tonneau. Cover its power, this and sonClose, and the property of cold and cool catharsis is crossed it, all lets out with heat-clearing and leads as controlling, all non-excess fires, cannot not absurdly throw. Being suitable for of all lung heresies reaches,But and be unsuitable for the person of falling, as measles from the beginning of, still do not give vent to, early throw and fall clearly, perseverance has the mechanism of qi of suppressing, the anxiety that renvoi caves in. Only oxAmong burdock is let out clearly, self energy is sent out thoroughly, and warm disease, and therefore stool, from logical, also can kill its gesture, less the burdock the most special medicine of measles.Great burdock achene is rich in linoleic acid, rutin, Quercetin, phytosterol, selenium, chromium, manganese. Can alleviate the pathologic of acute pancreatitis is damagedEvil, protection pancreatic tissue, strengthens insulin peripheral action, and anti peroxidation of lipid suppresses oxidative modification of high density lipoprotein, promotesCholesterol degradation is cholic acid excretion, reduces the permeability of capillary, and hemangiectasis is strengthened ascorbic effect and promoted dimensionRaw element accumulating in vivo.
From the flavor efficacy analysis of great burdock achene, its defaecation ease constipation mechanism relates generally to following three aspects:. One, ease constipation. OxBurdock is the seed of burdock, is rich in grease, and property is slided profit more. Modern pharmacological research shows, burdock main component is arctiin and fatFat oil, these compositions have the merit of the ease constipation of relaxing bowel. Clinical experience, the great burdock achene cold cunning of working hard, the logical lower effect of laxation is stronger, therebyTo constipation patient, the genus of house rheum officinale, saltcake, numb benevolence, aobvious this meaning of residence. Its two, lung qi falls. The lung is concerned with QI of the whole body, with large intestine is mutuallyIn table. Logical the falling of intestines internal organs, depends on a surname of lung qi respectful. It is respectful that lung loses a surname, and large intestine promotion is unable, causes FU QI being obstructed. Gu TongbianrunIntestines must first be controlled lung. Great burdock achene enters lung channel, can fall lung qi. As Zhang Xichun cloud: " the contrary of lung qi can fall in great burdock achene " " perillaseed, burdock are againCan clear phlegm fall contraryly, make contrary cyclostrophic and descending " (" Records of Tradition Chinese and Western Medicine in Combination "). With its defaecation ease constipation, there is the wonderful of " carry kettle and take off lid ". ItsThree, stomach Qi is fallen. Defeated large intestine under the descending swill of stomach Qi, then becomes stool and excretes. Great burdock achene enters stomach warp, " pungent rushing downHardship is fallen, and descending power is many " (" book on Chinese herbal medicine justice "), stomach Qi can be fallen, there is the effect of medicine for stomach dynamic. As Zhang Xichun cloud: " ... thereforeHelp it with the medicine that falls stomach again, ochre, dried orange peel, burdock in side are also " (" Records of Tradition Chinese and Western Medicine in Combination "). In a word, great burdock achene is cold in nature,Taste is arduous. The heat-clearing of cold energy, under hardship can be rushed down, Xin Nenghang is loose, is applicable to the malicious Tianjin of various heat and hinders constipation. As " medicine justice " cloud: " burdockSon can rise and can fall, power relieving heat toxin, and bitter can relieve inflammation or internal heat, and is with pungent energy dispelling wind, cures mainly ... all scorchingly hot heap soil or fertilizer over and around the rootss ... ".
Great burdock achene is rich in bioflavonoid, linoleic acid, chromium element. That great burdock achene flavones not only can be is effectively promoting blood circulation and removing blood stasis,Embolism resistance, reducing blood lipid, hypotensive, reduce cholesterol, reduce blood sugar, the composition of blood is purified, but also can improvesThe fragility of microcirculation, reduction capillary, reduces its permeability, can repair impaired vascular wall.
Poria cocos taste is sweet, light, property is flat, be used as medicine there is clearing damp and promoting diuresis, the function of beneficial spleen and stomach, antitoxic heart-soothing and sedative. Modern medicine grindsStudy carefully: Poria cocos energy enhanced machine body immunity function, pachymaran has significantly antitumor and protect the liver dirty effect. Poria cocos slightly sweet flavor is flat,Enter the heart, lung, the spleen channel. There is eliminating dampness and diuresis, strengthening the spleen and stomach, effect of antitoxic heart-soothing and sedative. Can control difficult urination, oedema turgor, phlegm and retained fluidCough contraryly, vomit contrary, vomiting during early pregnancy, has loose bowels, seminal emission, and stranguria with turbid discharge, palpitation with fear, forgetfully waits disease. The Li Shui of Poria cocos is to reach by strong fortune spleen PFTArrive, different from the Chinese medicine of other direct Li Shui. For splenasthenic diarrhea, the lower Poria cocos of band can invigorating the spleen, again can excreting dampness, and for insufficiency of the spleenDue to dysfunction of the spleen in transportation and transformation, have loose bowels, be with down, application Poria cocos has the effect of giving consideration to both the incidental and fundamental, the compatibilities such as normal and Radix Codonopsis, the bighead atractylodes rhizome, Chinese yam. Have availableFor tonifying lung spleen, control the adjuvant of the deficiency of vital energy.
Heart of a lotus seed benevolence is conventional Chinese medicine. be again the food of generally, often eating, property slightly sweet flavor is slightly cold, and has inducing diuresis for removing edema, invigorating the spleen to goWet, relaxing muscles and tendons removes the effects such as numbness, clearing away heat and eliminating pus, is conventional damp-clearing drug. Heart of a lotus seed benevolence is again a kind of beauty food, and normal food can be protectedHold human body skin gloss exquisiteness, eliminate acne, spot sparrow, senile plaque expelling, cyasma, butterfly macules, to furfur, acne, chap, skin is thickRough grade has good efficacy. The kind Renhe root of the seed of Job's tears can be used as medicine and cure the disease again. Li Shizhen (1518-1593 A.D.) is recorded in Compendium of Material Medica: seed of Job's tears energy "Invigorating spleen and reinforcing stomach, tonifying lung heat-clearing, removes wind prevailing over dampness. The food of cooking a meal, controls cold air. Decoct drink, diuresis heat is drenched. " in recent years, a large amount of science is groundStudy carefully with clinical practice and prove, the seed of Job's tears or a kind of cancer therapy drug, Preliminary Identification, it can reach more than 35% the inhibiting rate of cancer.
Bighead atractylodes rhizome bitter, sweet, temperature. Return spleen, stomach warp. Cure mainly strengthening the spleen and replenishing qi, eliminating dampness Li Shui, hidroschesis, antiabortive. For insufficiency of the spleen foodFew, abdominal distension is had loose bowels, and phlegm and retained fluid is dizzy throbs with fear, oedema, spontaneous perspiration, fetal irritability. The bighead atractylodes rhizome has CDCC to oncocyte, can reduce oncocyteThe rate of increase, lower the aggressive of tumor tissue, improve the ability of the antitumor reaction of body. Baizhu volatile oil is to mouse Emhorn ascitesCancer, lymphosarcoma ascitic type, the cancer of the esophagus (Ecal09), sarcoma 180 etc. have inhibitory action. Atractylodes lactone B lumbar injection is to mouseThe sarcoma people. Also there is remarkable inhibitory action. " property of medicine opinion " carries it: monarch, taste is sweet, pungent, nontoxic. The main large wandering arthritis of energy, diarrhea due to disorder of qi for many years, trusted subordinateDistending pain, the broken place food that disappears, appetizing, removes sputum, except fever and chills, under stopping, lets out. Interarea light is happy, preserves youthful looks, and de-black. The swelling of harnessing the river is full, tell vomit contrary,Crymodynia in abdomen, vomits and diarrhoea incessantly, and the cold dysentery of stomach Qi deficiency.
Red sage root hardship, is slightly cold. The thoughts of returning home, Liver Channel. Stasis-dispelling and pain-killing, activating blood to promote menstruation, relieving restlessness clears away heart-fire. For irregular menstruation, through closing painWarp, a lump in the abdomen causing distension and pain, chest ventral spine pain, hot numbness pain, sore swells and ache, dysphoria and insomnia. For sternal rib hypochondriac pain, arthralgia due to wind-dampness, abdominal mass knotPiece, sore swells and ache, fall fall forward grieved, irregular menstruation, through closing dysmenorrhoea, postpartum stasis of blood pain etc. Treatment sternal rib pain, abdominal mass caking, andIrregular menstruation, there is good effect through amenorrhoea pain. " detailed outline " carries: the red sage root, by " the sensible opinion of married woman " cloud, Siwu Tang is controlled gynecopathy, pays no attention toAntenatal postpartum, how many through water, all can be general, the only taste red sage root is loose, cures mainly identical with it. The lid red sage root can break place blood, mends new blood, peaceGreen tire, the stillborn foetus that falls, only metrorrhagia stagnant under, menstruation regulating arteries and veins. Main Compositions of Radix Salviae Miltiorrhizae tanshinone has hemangiectasis, improves circulation, removes blood vesselThe effects such as intravascular coagulation, have effect of invigorating blood circulation trace, and can promote liver blood circulation, are beneficial to liver cell regeneration.
The pungent micro-hardship of rhizoma cyperi is sweet, and flat function cures mainly: the Xie Yu that regulates the flow of vital energy, menstruction regulating and pain relieving. For stagnation of QI due to depression of the liver, chest, the side of body, gastral cavity abdominal distensionBitterly, indigestion, irregular menstruation, through closing dysmenorrhoea, cold hernia stomachache, swollen breasts. " detailed outline " carries it: the cold epidemic disease of gas when loose, and sharp three warmers,Xie Liuyu, the diet that disappears gathers, and phlegm and retained fluid ruffian is full, and instep is swollen, abdominal distension, beriberi, only trusted subordinate, limbs, head, order, tooth, all pains of ear, ulcer soreUlcer, spits blood, lower blood, and hematuria, under married woman's uterine bleeding band, month time is uncomfortable, tire all kinds of diseases and ailments in front postpartum.
Root tuber of aromatic turmeric is pungent, bitter, cold. Return liver, the heart, lung channel. Function cures mainly regulating qi to disperse stagnation, heart fire-clearing upset-relieving, normalizing gallbladder to cure jaundice. Be used for through closingDysmenorrhoea, chest and abdomen swelling and pain, shouting pain, pyreticosis coma, epilepsy is gone mad, and jaundice urine is red. Promoting qi circulation and removing obstruction in the collateral, cool blood breaks the stasis of blood. Control chest abdomen side of body rib allBitterly, lose the heart demented, pyreticosis coma, spits blood, bleeding from five sense organs or subcutaneous tissue, and hematuria, blood drenches, women's vicarious menstruation, jaundice. " property of medicine opinion " carries it: control woman placeVim and vigour are pained, and cold air knot is poly-, and warm vinegar rubs and takes it. Tang Materia Medica carries it: main blood is long-pending, lower gas, and myogenic, hemostasis, broken extravesated blood, blood drenches,Hematuria, metal-inflicted wound.
The Radix Astragali has the effects such as invigorating qi for strengthening superficies, sharp water detumescence, pus draining and toxin expelling, myogenic. The medicinal of the Radix Astragali has 2000 so farHistory for many years, modern study, the Radix Astragali is containing lot of traces such as saponin, sucrose, polysaccharide, several amino acids, folic acid and selenium, zinc, copperElement. Have enhanced machine body immunity function, protect the liver, diuresis, anti-ageing, anti-stress, step-down and antibacterial action more widely. But table is realEvil Sheng, retention of dampness due to stagnation of QI, dyspepsia is stagnated, ulcer from the beginning of or the real example such as routed after heat poison Shang Sheng. The Radix Astragali has invigorating qi for strengthening superficies, diuresis holderPoison, apocenosis, effect of expelling pus and promoting granulation. Weak for the deficiency of vital energy, anorexia and loose stool, the sinking of qi of middle-jiao, rushes down prolapse of the anus for a long time, the uterine bleeding of having blood in stool, exterior deficiencySpontaneous perspiration, ulcer is difficult bursts, and bursts and does not hold back for a long time, and the deficiency of blood is sallow, and interior heat is quenched one's thirst. " herbal classic " recorded: " main ulcer, loses sore for a long time, apocenosis pain relieving.Qi-restoratives, children's's all kinds of diseases and ailments. " " Japan hanako materia medica " record: " help gas to strengthen the bone, put on flesh and enrich blood. "
Dragon's blood has promoting blood circulation to remove blood stasis, analgesic therapy, effect of hemostasia and promoting granulation. Effect: promoting blood circulation to remove blood stasis for oral administration, analgesic therapy, external application hemostasisMyogenic, sore. Cure mainly: 1. extravasated blood through closing, dysmenorrhoea, postpartum stasis blocking. 2. abdominal mass lump in the abdomen, chest ventral spine pain. 3. traumatic injury, extravasated blood is swollenBitterly. 4. traumatism and bleeding, unhealing ulcer. Property sugariness become. " Haiyao Bencao, Oversea Materia Medica ": leadingly traumatic fracture damage, all pain, qi-restoratives and vim and vigour are stirredThorn, interior blood trouble is poly-, and should wine clothes. " Japan hanako materia medica ": control all evil sore mange and do not conform to person for a long time, apply. This property of medicine is anxious, also can not be manyMake, but draw purulence.
The root bark of white mulberry is the root skin of moraceae plants mulberry MorusalbaL.. Main product in Anhui, Henan, Zhejiang, Jiangsu, HunanEtc. ground. Effect: removing heat from lung and relieving asthma, inducing diuresis for removing edema. Cough and breathe heavily for lung heat, the edema of the face, the diseases such as difficult urination. " property of medicine opinion ": make,Flat. Can control lung qi and breathe heavily completely, aqueous vapor edema, main wound is exhausted, dredging water passages, the aqueous vapor that disappears, the headache of consumptive disease visitor heat, interior tonifying for the deficiency. " solar corona originallyGrass ": temperature, in tune, lower gas. Dissolving phlegm is quenched the thirst, sharp intestine and small intestine, and appetizing, lower food, kills abdomen and hides worm, and only cholera is vomited and diarrhoea.
Motherwort taste is arduous, cool. Invigorate blood circulation, dispel silt, menstruation regulating, water disappears. Treatment menoxenia, threatened abortion difficult labour, afterbirth is notUnder, postpartum anemic fainting, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, the carbuncle sore that swells. Motherwort is containing leonurine, fumaric acid etc.Material, has the effects such as promoting blood circulation for regulating menstruation, hypotensive, inducing diuresis to reduce edema.
The fruit of glossy privet is secretly not clear for the order of the deficiency of liver-yin and kidney-yin, hypopsia, poliosis, soreness of waist tinnitus and fever due to yin deficiency etc.This product energy tonifying liver kidney yin, but the efficacy of a drug is gentle, must slowly get effect. Control order secretly not clear, often join cultivated land, matrimony vine is equal to use, controls beard and hair earlyIn vain, often join the same use of mulberries, fever due to yin deficiency, often joins the root bark of Chinese wolf-berry. The deficiency of liver-yin and kidney-yin, Light-headedness, seminal emission tinnitus, soreness and weakness of waist and knees, beard and hairEarly white, coronary heart disease, hyperlipidemia, hypertension, chronic hepatitis. The protective effect of liver research is thought, the fruit of glossy privet contains neat pierTartaric acid, gives rat skin lower injection, can reduce serum glutamic pyruvic transminase, has obvious protection to do to the hepatic injury of Carbon Tetrachloride InducedWith, and can promote liver cell regeneration. oleanolic acid also can make that in liver, triglycerides is accumulated minimizing, degeneration of liver cells necrosis obviously subtractsGently, glycogen is accumulated increase, serum γglobulin declines; In the visible liver cell of ultra microstructure, mitochondrial swelling and endoplasmic reticulum vesica becomeProperty alleviates, the inflammatory reaction of hepatic tissue interstitial weakens.
The root of herbaceous peony enters liver, the spleen channel, nourishing blood and liver, and slow middle pain relieving, astringe yin is received sweat. Control chest abdomen pain over the hypochondriac region, rush down dysentery stomachache, spontaneous perspirationNight sweat, fever due to yin deficiency, irregular menstruation, uterine bleeding, under band, married woman's blood closes obstructed, and the hemostasis that disappears can lose purulence, beneficial woman's blood. " solar coronaBook on Chinese herbal medicine ": control wind, mend labor, all diseases of main woman, and antenatal rear all diseases, Tong Yueshui, brings down a fever, relieving restlessness, beneficial gas, day hot disease of row, pestMiasma, frightened mad, married woman's blood fortune, and intestines wind, rush down blood, hemorrhoid complicated by anal fistula. Carbuncle on the back, sore scabies, headache, improving eyesight, hot eyes is exerted meat. The many tonifying Qi of redness of the skin or complexion person,White person controls blood.
Radix polygonati officinalis: nourishing Yin and moistening lung; Nourishing the stomach to improve the production of body fluid. Cough caused by dryness; Labor is coughed; The dry throat and mouth of the cloudy liquid consumption of pyreticosis wound; Interior heat is quenched one's thirst; The deficiency of YinDiseases caused by external factors; Dizzy dizzy; Muscle arteries and veins contraction pain. The sweet greasiness of radix polygonati officinalis taste, matter is soft and moisten, and is the good medicine of nourishing Yin and promoting production of body fluid simply. Contained in radix polygonati officinalisVitamin A, improve dry and cracked, rough skin situation, make it soft lubricated. Play the effect of beauty and skin care. " book on Chinese herbal medicine is through collectionNote " " stem is tetanic, like bamboo arrow shaft, has joint for cloud. Therefore " there is the name of radix polygonati officinalis. The rhizome of plant can hyoscine, and Chinese medicine name is also radix polygonati officinalis,Excavate autumn, cleans, and shines to softness, repeatedly rubs, and airing, to without hard-core, is dried, or after steaming thoroughly, rub to translucent, dry,Cut sheet or section use. " book on Chinese herbal medicine justice ": " control lung stomach scorching, body fluid dries up, and thirsty choke is dry waits disease, and exuberance of stomach fire, dryly yearningly disappearsPaddy, polyorexia person, You Youjie effect ".
Flos Albiziae contains silk tree glucoside, tannin, and resolving stagnation for tranquilization, the appetizing of regulating the flow of vital energy, activating collaterals to relieve pain, loses for confused and worried, melancholySleep. Control pent-up uncomfortable in chest, insomnia, forgetful, acute conjunctivitis, can five viscera settling, and will, happy color, have preferably keep fit, calm, calm the nerves,The effect of beauty treatment is also the neurasthenic good merchantable brand for the treatment of. Also there is clearing away summerheat, face-beautifying and spot-removing effect such as relieve the effect of alcohol. " book on Chinese herbal medicine warp "Say: " Flos Albiziae energy five viscera settling, and will, happy color. " especially to pregnant woman, have preferably keep fit, calm, the work of calming the nerves, improving looksWith, be also the neurasthenic good merchantable brand for the treatment of.
Reticulate millettia property hardship, sweet, temperature. Return liver, kidney channel, enrich blood, invigorate blood circulation, dredging collateral. For irregular menstruation, the deficiency of blood is sallow, numbnessParalysis, arthralgia due to wind-dampness is activated blood and relaxed tendons; Nourishing blood for regulating menstruation, supplementary Amplifications of the Compendium of Materia Medica carries it can cure numb in every limb; Quadriplegia; Rheumatism numbnessBitterly; Women has through uncomfortable; Dysmenorrhoea. External application is the gynaecology's good medicine activating blood circulation and dispersing blood clots.
Bletilla hardship, sweet, puckery, is slightly cold. Return lung, liver, stomach warp. Function cures mainly astringing to arrest bleeding, detumescence and promoting granulation. Tell for hemoptysisBlood, traumatism and bleeding, sore swollen toxin, chapped skin; Pulmonary tuberculosis hemoptysis, ulcer haemorrhage. Shennong's Herbal: " main carbuncle is swollen, evilSore, lose subcutaneous ulcer, the dead flesh of impairment of yin, perverse trend in stomach "; Compendium of Material Medica: " smell (root) is bitter, flat, nontoxic.
Root of Dahurain angelica meridian distribution of property and flavor: pungent, temperature. Attach to the lung and stomach meridians. Expelling wind and clearing away cold, understand things pain-stopping, detumescence and apocenosis, eliminating dampness is band only. " dayChina's son book on Chinese herbal medicine ": control the hot eyes triangular mass of mucous membrane growing from the inner corner of the eye, and tire patching leakage landing, broken place blood, mends new blood, acute mastitis, carbuncle on the back, scrofula, intestines wind, hemorrhoid complicated by anal fistula, rowPurulence, desolation, mange, pain relieving myogenic, goes face Shao-defect scar.
Pseudo-ginseng, Latin formal name used at school: PanaxNotoginseng (Burk.) F.H.Chen. Have another name called pseudo-ginseng, return Liver Channel; Stomach warp;The heart channel of Hang-Shaoyin; Lung channel; Large intestine channel. Function: hemostasis; Loose blood; Analgesic therapy. Cure mainly: fall that to flutter the stasis of blood swollen, obstruction of qi in the chest angina, abdominal mass; Blood stasis is through closing; BitterlyWarp; The cloudy stomachache of the stasis of blood in postpartum; Sore, carbuncle and painful swelling. The famous pharmacy man Li Shizhen (1518-1593 A.D.) of the Ming Dynasty is called " invaluable ". Pseudo-ginseng is in Chinese medicineA jewel, in Qing Dynasty's pharmacy works supplementary Amplifications of the Compendium of Materia Medica, record: " ginseng qi-tonifying the first, pseudo-ginseng enriches blood the first, taste with andMerit also etc., therefore claim Panax pseudoginseng, is the most precious person in Chinese medicine. Pseudo-ginseng has anti-liver injury effect. PNS can significantly reduce CCl4Hepatic injury mice serum ALT activity. The Liver Damage in Rats that methanolic extract causes CCl4, D mono-galactosamine, can significantly reduceIn rat blood serum, AST and lactic dehydrogenase (LDH) activity, alleviates degeneration of liver cells necrosis. Pseudo-ginseng also has anti-hepatic fibrosisEffect, to the hepatic injury of N-nitrosodimethylamine poisoning rat, treats 4 weeks with Radix Notoginseng powder, degeneration of liver cells necrosis is alleviated, liver cellBetween collagenous fibres reduce. To the poisoning hepatic fibrosis rats of CCl4, in giving CCl4 moulding, oral Radix Notoginseng powder prevents and treats 9In week, can alleviate liver fat sex change, inflammatory cell infiltration, degeneration of liver cells necrosis. Be reduced to the hyperplasia of fibrocyte and collagen.Pseudo-ginseng has certain choleretic effect, and the Rabbit Liver internal congestion jaundice that Radix Notoginseng injection causes a-α-naphthyl isothiocyanate hasSignificantly reduce serum bilirubin, promote choleresis effect. Pseudo-ginseng promotes hepatic protein synthetic, increases 3H-TdR to impaired liverDirty DNA mixes speed, increases the mix speed of 3H-leucine to hepatic protein.
Radix Angelicae Sinensis, its taste is sweet and weigh, therefore specially can enrich blood, its gas is light and pungent, thus again can promoting circulation of blood, bowl spares has, in row, has benefit, reallyGas medicine in blood, the also panacea in blood. Approximately mending to mend of assistant, thus can support nutrition blood, tonifying Qi production of sperm, five viscera settling, strong body,Benefit mind, all tangible deficient diseases, unsuitable without institute. Assistant logical to attack, thus the pain defaecation of dispelling, relieving rigidity of muscles and joints, control contraction, paralysis,The card such as dry, puckery. Seek void and exterior syndrome being not relieved person, help with agent such as bavin, Pueraria lobota, fiber crops, osmanthus, the Biao Weire that can fall apart greatly, and table is not held back person, assistant is with rheum officinaleAnd so on, can admittedly show again. Precisely because gas Xin Erdong, thus want its quiet person when keeping away it, the sliding benefaction of property, stool is not consolidated person when keeping away it. In all the moonFire Sheng person, the active blood of Radix Angelicae Sinensis, also non-institute is suitable, cloudy deficiency of YANG of middle-JIAO person, Radix Angelicae Sinensis can nourish blood, and is indispensable
Raspberry is warm in nature; Sweet, sour; Return kidney, urinary bladder channel. Cure mainly: kidney-nourishing, controlling nocturnal emission with astringent drugs, contracting urine. For enuresis with renal asthenia, urine frequentlyNumber, impotence and premature ejaculation, emission and spermatorrhea. " Bencao Jingshu ": " raspberry, its main beneficial gas person, says beneficial vital essence also. Kidney storing essence, kidney are received gas,Vital essence abundance, body, from light, is sent out in vain not also. The respectful main qi-restoratives of reviving is absolutely continuous, reinforcing yin essence Jianyang, smoothing skin, peace and internal organs. The main man of Zhen QuanSub-kidney-jing deficiency exhausts, impotence, woman's food have a son. Large bright main five viscera settling, beneficial color, supports vital essence, long hair, Qiang Zhi. All get its kidney-nourishingAdd essence, the adopted ear of sweet acid convergence. " " property of medicine opinion " carry its: " main man's kidney-jing deficiency exhausts, woman's food have a son. Main impotence. "
Bitter temperature a surname of dessert almond lung, relaxes bowel, is only suitable for the trouble of the real examples such as ailment said due to cold or exposure, intestines be dry. All the moon loses, stagnated fire person,Unsuitable simple is for oral administration for a long time. As the disease taboo simples such as pulmonary tuberculosis, bronchitis, chronic enteritis, dry cough without phlegm take for a long time. Chinese medicineIn ancient books and records Compendium of Material Medica, enumerate three large effects of dessert almond: moistening lung, clear having indigestion, loose stagnant. Clear having indigestion is to say that dessert almond can helpAid digestion, relief of constipation symptom; " modern Practical Chinese medicinal " recorded: " dessert almond is for oral administration has laxative effective, and has the effect of nourishing. "For old chronic constipation person, taking the better sweet dessert almond of dessert almond effect is a kind of healthy food, in right amount foodWith the content that not only can effectively control cholesterol in human body, can also significantly reduce the morbidity danger of heart disease and multiple chronic diseaseDanger. The edible sweet dessert almond of vegetarian can supplement protein, trace element and vitamin, for example iron, zinc and vitamin E in time.In dessert almond, contained fat is that healthy personage is necessary, is a kind of high unsaturated fat useful to heart. Research discovery,Eat 50～100 grams of dessert almonds (about 40～80 dessert almonds) every day, body weight can not increase. Protein content not only in dessert almondHeight, a large amount of fibers wherein can allow people reduce hunger, and this is just to keeping body weight useful. The useful intestinal tissue of fiber and canReduce the intestinal cancer incidence of disease, cholesterol level and cardiopathic danger. So overweight people selects sweet dessert almond as snacks, canReach the effect of controlling body weight. Nearest scientific research also shows, dessert almond can promote skin microcirculation, makes the ruddy light of skinPool, has effect of beauty treatment.
Sealwort: sealwort is used as medicine with rhizome. There is boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney benefiting functions. Be used for the treatment of weakness of the spleen and the stomach,Fatigue and asthenia, dry food is few, deficiency syndrome of the lung cough caused by dryness, asthenia of essence and blood, the interior heat disease such as quench one's thirst. Very effective in cure for diabetes. Sealwort hasHypotensive, hypoglycemic, reducing blood lipid, atherosclerosis, delays senility and effect such as antibacterial grade, and Siberian solomonseal rhizome polysaccharide has immunity and swashsLive and act on. For the lung-dryness syndrome due to yin deficiency, the few phlegm of dry cough, and the labor of the lung-kidney deficiency chronic cough etc. of coughing. For weakness of the spleen and the stomach. Both tonifying spleen-yin, againBenefit temper, obtain for deficiency of kidney essence dizzy, soreness and weakness of waist and knees, poliosis and quench one's thirst etc. Sealwort strengthens the bone, and beneficial marrow bleaches and sends out;Be suitable for cough phlegm due to lack of lung-YIN few, dry cough without phlegm, the diseases such as hemoptysis.
The pungent one-tenth of the larva of a silkworm with batrytis is flat. Expel endogenous wind to relieve convulsion, reducing phlegm and resolving masses. Control apoplectic aphasia, frightened epilepsy, a wind, sore-throat. Larynx numbness, scrofula knotCore. Wind sore urticaria, erysipelas, mastitis. " herbal classic ": the main pediatric epilepsy scared morbid night crying of babies, go three worms, Mie Hei über, the cloudy ulcer disease of man. " notRecord ": woman's metrorrhagia is red white, postpartum She's pain, all sore scars of going out. The larva of a silkworm with batrytis is loaded with in " Sheng Nong's herbal classic " that " blackspot that goes out, makes us complexionEffect well ". The larva of a silkworm with batrytis contains amino acid and active mercerising element, nutritious skin and beautification function. The contained protein of stiff silkworm hasSebaceous glands in stimulation, the effect of modulability hormone secretion, thereby the chloasma that Female Sexual Hormones dyssecretosis is caused has necessarilyCurative effect. Stiff silkworm, containing vitamin E 9.89%, can be removed free radical, the senile plaque expelling that anti-lipid oxidation forms. The active mercerising that it is containedElement can impel Skin Cell new life, regulate sebum, improve skin microcirculation, can brighten sun-proof, eliminate pigmentation, keep skinElasticity. Japanese just very likes and uses silk health products. If can use silk cocoon, silkworm chrysalis to replace without stiff silkworm. The larva of a silkworm with batrytis contains oxamide, alsoThere is protease, chitinase, the hydrolases such as lipase can digest cutin, decompose the anti-scar of pigment and go acne to control the effect of ecchymosis.
Kaladana, Latin formal name used at school: Pharbitisnil (Linn.) Choisy, cold in nature, bitter; Poisonous. Composition: containing leading a cowSub-glucoside (resin glucoside), fat oil, organic acid etc. Function cures mainly: water pouring defaecation, and drink is washed in dissolving phlegm, and desinsection is attacked long-pending. Swollen for oedemaFull, constipation and anuresis, phlegm and retained fluid is gathered, and the circulation of vital energy in the wrong direction is breathed with cough, abdominal pain due to enterositosis, roundworm, taeniasis. Gui Jing: return lung channel, kidney channel, large intestine channel. ToolHave rush down under, the effect such as diuresis, detumescence, expelling parasite, cure mainly edema of limbs and trunks, nephritic dropsy, cirrhotic ascites, constipation, abdominal pain due to enterositosis etc.Disease. Concoct kaladana: get crude drug, choose decontamination, clean earth with clear water, dry. Stir-baked SEMEN PHARBITIDIS, gets kaladana, puts stir-fry medicineIn pot, stir-fry to micro-ly heaving, thoroughly when fragrance, aobvious heat color, take out spreading for cooling with low baking temperature heating. The accidental coke yellow of finished product. After stir-fry, canRelax the effect of its sharp water defaecation.
Specific embodiment 1:
First, by great burdock achene preparation, stir-fry. Again great burdock achene is added water or alcohol extract.
Again by all the other raw material radix polygonati officinalis, dragon's blood, Radix Angelicae Sinensis, pseudo-ginseng, bletilla, Poria cocos, the red sage root, raspberry, dessert almond, the root bark of white mulberry,Sealwort, root tuber of aromatic turmeric, rhizoma cyperi, the Radix Astragali, heart of a lotus seed benevolence, the bighead atractylodes rhizome, Flos Albiziae, motherwort, reticulate millettia, the larva of a silkworm with batrytis, the fruit of glossy privet, the root of Dahurain angelica, kaladana,Add water or ethanol is condensed into extract.
Mix the extract of great burdock achene extract and other raw materials, add appropriate dextrin ultraviolet radiation for sterilizing and disinfecting bottling, useIn time, directly drinks.
Specific embodiment 2:
Get great burdock achene 5000g and clean, the airing time, at 7-12 hour, parches; The good great burdock achene of airing is put into and killedIn blue or green pot, go green grass or young crops, the 30-45 minute that completes at 80-100 DEG C, then puts into large iron pan and stir-fries, first backward upper downwards, usesPower is wanted evenly, when great burdock achene color starts blackout, starts the moulding in 30-45 minute that stir-fries of little fire; In the time that color becomes pitchy, getGo out naturally to dry afterwards; The great burdock achene that frying is good is put into 10 times of amount ethanol, heating and refluxing extraction 2 times, and each 1～2 hour, by 2Inferior extract merges standing; The great burdock achene dregs of a decoction of more above-mentioned alcohol extract being crossed add 10 times of water gaging heating and refluxing extraction 2 times, each1～2 hour, No. 2 extracts are merged and left standstill; Above-mentioned two kinds of extracts are merged, and after recovery ethanol, inspissator is put in decompressionConcentrated, gained concentrate is adjusted to proportion to 1.06, decompression recycling ethanol, obtains great burdock achene extract; By surplus stock radix polygonati officinalis1500g, dragon's blood 1500g, Radix Angelicae Sinensis 1500g, pseudo-ginseng 1500g, bletilla 1500g, Poria cocos 1500g, red sage root 1500g, raspberry1500g, dessert almond 1500g, root bark of white mulberry 1500g, sealwort 1500g, root tuber of aromatic turmeric 1500g, rhizoma cyperi 1500g, Radix Astragali 1500g, heart of a lotus seed benevolence1500g, bighead atractylodes rhizome 1500g, Flos Albiziae 1500g, motherwort 1500g, reticulate millettia 1500g, larva of a silkworm with batrytis 1500g, fruit of glossy privet 1500g,Root of Dahurain angelica 1500g, kaladana 1500g, cleans impurity elimination, dries, and is ground into particle, soaks 1 hour; By soaked bulk drugPut boiling secondary in multi-function extractor; Add up for the first time the water of 10 times of amounts of medicinal material, decoct 1.5～2 hours, get decocting liquid,Filter; Add up for the second time the water of 7 times of amounts of medicinal material, decoct 1～1.2 hour, get twice decocting liquid and mix, filter; By the filtrate of filteringInsert in economic benefits and social benefits vacuum concentrator, the concentrate that while being concentrated into 90 DEG C, relative density is 1.05, set to 0～5 DEG C of deepfreezes 24 are littleTime; Refrigeration liquid is added to 0.3% filter aid diatomite, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1mlContaining 1g crude drug amount, add the agent of dextrin granulation. Again great burdock achene extract is mixed with other raw material extracts of making, add dextrinBe in harmonious proportion, ultraviolet disinfection, packs and get final product.
Specific embodiment 3:
Raw material great burdock achene 3000g is cleaned, and the airing time, at 7-12 hour, parches; The great burdock achene that airing is good is putEnter to complete in pot and go green grass or young crops, the 30-45 minute that completes at 80-100 DEG C, then puts into large iron pan and stir-fries, first backward downwardsUpper, firmly want evenly, when great burdock achene color starts blackout, start the moulding in 30-45 minute that stir-fries of little fire; When color becomes pitchyTime, after taking out, naturally dry; The great burdock achene that frying is good is put into 10 times of amount ethanol, and heating and refluxing extraction 2 times is each 1～2 littleTime, No. 2 extracts are merged and left standstill; The great burdock achene dregs of a decoction of more above-mentioned alcohol extract being crossed add 10 times of water gaging heating and refluxing extraction 2Inferior, each 1～2 hour, No. 2 extracts are merged and left standstill; Above-mentioned two kinds of extracts are merged, and after recovery ethanol, decompression is put into denseConcentrated in contracting device, gained concentrate is adjusted to proportion to 1.06, decompression recycling ethanol, obtains great burdock achene extract; And then willSurplus stock radix polygonati officinalis 1200g, dragon's blood 1100g, Radix Angelicae Sinensis 1200g, pseudo-ginseng 1300g, bletilla 1200g, Poria cocos 1100g, the red sage root1300g, raspberry 1200g, dessert almond 1300g, root bark of white mulberry 1200g, sealwort 1200g, root tuber of aromatic turmeric 1100g, rhizoma cyperi 1200g, the Radix Astragali1100g, heart of a lotus seed benevolence 1200g, bighead atractylodes rhizome 1200g, Flos Albiziae 1100g, motherwort 1200g, reticulate millettia 1200g, larva of a silkworm with batrytis 1300g, femaleLoyal sub-1200g, root of Dahurain angelica 1200g, kaladana 1100g, puts it in 10 times of water gagings and soaks. Drop into multi-function extractor and extract twoInferior, add for the first time 8-10 times of water gaging and decoct 1-2 hour, add for the second time 4-8 times of water gaging and decoct 1-2 hour, merge twice decocting liquid, mistakeFilter to obtain filtrate; Heating is concentrated into pasty state, mixes after great burdock achene extract, adds dextrin and is in harmonious proportion, canned after ultraviolet radiation for sterilizing and disinfecting.
Pharmacology toxicity test
Health products acute toxicity test of the present invention
One, test material:
Animal: Kunming mouse, body weight 21-24g, male and female half and half, Shandong University's biology laboratory breeding. Medicine: thisBright health products, containing 0.0365g crude drug/g.
Two, method:
1, LD50 calculates: adopt improvement karber's method, mouse is divided into 5 groups at random, 10 every group, male and female half and half, by thisBright adding distil water dissolves, and is made into Cmax, and by the administration of the maximum permission capacity of mouse, institute is followed successively by 18 to dosage by crude drug amount,14.4,11.5,9.2,7.4 (g.kg-1), in animal fasting (can't help water) after 18 hours, in one day the (interval half of administration at twiceHour), each 0.5ml, observes animal dead situation.
2, maximum tolerated dose is measured (MTD value): get 20 of mouse, each 10 of male and female. Adding distil water of the present invention is dissolved,Be made into maximum concentration, by the maximal tolerance dose of animal, feed device and can twitch and be as the criterion to inject to fill with. Little at animal fasting (can't help water) 18Shi Hou, feedwater (interval half an hour) at twice in a day, each 0.5ml (every ml is containing crude drug 0.036g), total dose is that 18g is rawMedicine/kg.d, 300 times of quite clinical adult 50Kg body weight consumption. Continuous Observation 7 days after administration.
Three, result of the test:
In calculating, LD50 in the time giving mouse with maximum acceptable concentration and maximum permission capacity (18g/Kg.d), has no littleMouse death, does not measure LD50, asks only maximum tolerated dose, in 7 day observation period, and its appetite of animal, activity, hair color, essenceGod's states etc. are all normal, grow normally, there are no death. Select 300 times of doses that are equivalent to clinical dosage, there is no bad anti-Should occur, show that acute toxicity is minimum, MTD > 18g/Kg.d.
Long term toxicity test data of the present invention
Chinese medicine of the present invention is through the gastric infusion long-term toxicity test for animals result of 6 months: SD rat is divided into three groups, every group30, male and female half and half (being divided into high, medium and low three dosage groups, 10 every group), wherein first group through gavage to physiological saline; TheTwo groups are given dosage of the present invention through gavage is 0.25g, 2.5g and 12.5g/kg.d; The 3rd group through gavage the dosage to LovastatinFor 0.5mg, 5.0mg and 50.0mg/kg.d. During administration, observe respectively clinical manifestation, blood after each treated animal administrationThe indexs such as, blood biochemistry, organ coefficient and histopathology are carried out the evaluation of drug toxicity. Result of study: main toxic reactionShow Lovastatin 50mg/kg.d and 5.0mg group, show that salivation, fluffy, busy, the abdomen of hair have appearred in SD rat after administrationRush down, reaction and the symptom such as step, total food ration and losing weight; Blood test shows that total white blood cells increases to some extent, red blood cellSum, content of hemoglobin and platelet count obviously decline (the equal < 0.05 of P); Blood biochemistry checking shows ALT, AST, ALPWith 1～8 times (equal < 0.05 of P) of CK rising, creatinine and urea nitrogen raise (the equal < 0.05 of P) to some extent, but do not cause animal dead; GroupKnit pathological analysis result and show that Lovastatin 50mg/kg.d group has occurred that the liver-kidney diseases reason similar to people changes. And physiology saltTri-dosage groups of water group and 0.25g of the present invention, 2.5g and 12.5g/kg.d and Lovastatin 0.5mg/kg.d dosage group are wholeDuring administration, all there is not similar reaction, at convalescence viewing duration, occur that the symptom of each treated animal of reaction fades away extensiveMultiple normal condition. Visible the present invention not only can reduce the toxic and side effect of Lovastatin, and can make the clinical nothing of LovastatinToxic agent amount is increased to 5～25 times (the equal < 0.01 of P).
Pharmacological experiment:
1 material
1.1 animals: 60 of healthy 3 monthly age pure lines Kunming kind female mices, body weight 25～35g, University Of Qingdao animal used as testThe department of the Chinese Academy of Sciences provides. Animal feeding condition: every group of mouse is by group sub-cage rearing. In the situation that natural conditions are identical, routine is raised foodDrinking-water, keeps natural lighting, and without undesirable element impact, raise and within 1 week, adapt to start to test after experimental situation,
1.2 experimental drugs: spot-removing beautifying face oral liquid of the present invention, by great burdock achene, radix polygonati officinalis, dragon's blood, Radix Angelicae Sinensis, pseudo-ginseng, bletilla, FuSiberian cocklebur, the red sage root, raspberry, dessert almond, the root bark of white mulberry, sealwort, root tuber of aromatic turmeric, rhizoma cyperi, the Radix Astragali, heart of a lotus seed benevolence, the bighead atractylodes rhizome, Flos Albiziae, motherwort, chicken bloodRattan, the larva of a silkworm with batrytis, the fruit of glossy privet, the root of Dahurain angelica, kaladana presses the method preparation of embodiment 2, concentration: 1.2g/ml, Pharmacy of the court produces.3% Hydrochinone Cream: Pharmacy of Wuhan Hospital of Traditional Chinese Medicine produces, lot number 20050905. Progesterone injection: the celestial jade pendant pharmacy in Zhejiang shareCo., Ltd, lot number: 20050115.
1.3 reagent: vulcanized sodium (NaS): the limited public affairs of extra large Ling Feng chemical reagent can, lot number: 20020118, be made into before use10% aqueous solution. Superoxide dismutase (SOD), MDA (MDA) kit: Bioengineering Research Institute is built up in Nanjing, lot number:20059116。
1.4 key instruments: DY89-II type electric driven glass refiner: Xin Lan biotech inc, Ningbo. SystemBiomicroscope: OLYMPUS; BX50F4 Beijing Institute of Aeronautics pathological image analytical system.
2 experimental techniques
2.1 modellings: with reference to chloasma experimental animal model clone method. After mouse 2.5% yellow Jackets anesthesia,Press the intramuscular injection of 0.02g/kg dosage mouse hind leg, 6 times weekly, continuous 4 weeks with 0.4% progesterone injection. Normal group is pressed0.02g/kg intramuscular injection sterilized water for injection.
2.2 animal grouping and administrations: get 60 of Healthy female mouse, 3 dosage groups, are divided into 6 groups at random, 10 every group.Normal group, model group, 3 dosage groups of spot-removing beautifying face oral liquid of the present invention (0.15,0.3,0.6g/g), 3% quinhydrones positive controlGroup (0.6g/g). 3 dosage treatment groups of spot-removing beautifying face oral liquid of the present invention are respectively in mouse modeling medication on the same day, every day 1 time, everyWeek 6 times, continuous use 30 days. Normal group and model group give distilled water in the corresponding time; 3% quinhydrones positive drug control group is in makingMould started local application the same day, and time and the course for the treatment of are with spot-removing beautifying face oral liquid treatment group.
2.3 observation index and detection: medication is after 30 days, mouse is put to death in cervical vertebra dislocation, back unhairing, get rapidly hepatic tissue andEach 2 of the skin histology at coating position, wherein removes blood with ice-cold normal saline flushing for one, and filter paper blots, and cuts liverThe each 0.5g of dirty and skin, puts into respectively the beaker of the pre-cold saline of 2.0ml, shreds tissue, then pours in test tube, with at a high speedDisperser 10r/min homogenate twice, each 10 seconds; With 3500r/min rotating speed centrifugal 15 minutes again, get supernatant. Adopt yellow fastPurine oxidation enzyme process, detects description method by kit and measures SOD; Adopt thiobarbituricacidα-method, detect explanation by kitBook method is measured MDA value. Meanwhile, separating mouse skin of back, gets one of plucked skin histology (2cm*1cm left and right), 10%Paraformaldehyde is fixed, routine paraffin wax embedding, and section, HE dyeing, conventional organization pathological examination, om observation, counting epithelial proliferation,Corium blood vessel number and chorionitis cell number; Immunohistochemical staining, observes melanocyte dyeing and number (positive cell: nothing, meter0 point; < 15%, counts 0.5 point, and < 30% counts 1 point; 30% 2 points of >).
2.4 statistical methods: relatively t inspection between measurement data employing group; Layering calculating chart adopts rank test to carry outStatistical disposition.
3 results
The mensuration of 3.1 each group mouse skins, hepatic tissue MDA, SOD content is in table 1.
The mensuration of table 1 each group mouse skin and hepatic tissue MDA, SOD content (x ± s)
With relatively * P < 0.05.**P < 0.01 of model group; With relatively #**P < 0.05 of positive group
It is visible that 3.2 each group mouse skin Pathomorphologics and immunohistochemistry are observed PATHOMORPHOLOGICAL OBSERVATION OF PULLORUM: justThe epithelial layer cell arrangement of normal group mouse skin is neat, without hyperplasia, has no little blood vessel dilatation in skin corium, and inflammatory cell is rare.The epithelial layer hyperplasia of model group mouse skin is obvious, the large and arrangement disorder of core, visible little blood vessel dilatation in skin corium, inflammatoryCell is common. The epithelial layer hyperplasia of dosage group big or middle and positive controls mouse skin alleviates to some extent, and arrangement disorder subtractsGently, in skin corium, little blood vessel dilatation alleviates, and inflammatory cell is rare. The results are shown in Table 2.
Immunohistochemical PATHOMORPHOLOGICAL OBSERVATION OF PULLORUM is visible: in normal group mouse epithelial layer, visible a little melanin is thinBorn of the same parents, the painted sepia of endochylema. Visible a large amount of melanocytes in model group mouse epithelial layer, the painted dark brown of endochylema, and positiveCell number > 30%. Visible black color element cell in dosage group big or middle and positive controls mouse epithelial layer, it is brown that endochylema color depthLook, positive cell number reduces, in table 2.
Table 2 each group mouse skin histopathology morphology and melanocyte observed result (n)
Rank test; With relatively * P < 0.05 of model group, * * P < 0.01
4 discuss
The chloasma traditional Chinese medical science is called " chloasma hepaticum ", belongs to motherland's medical science " dark spot " or " dusty complexion " category. It is generally acknowledged that this disease occursDirty in close relations with liver,spleen,kidney three.
Theory of traditional Chinese medical science is thought " lung governing skin and hair ", as " (Plain Questions " six joint state of internal organs opinion clouds: lung person, the dominator of QI, the position of storing soul also, itsHua Mao, it fills at skin, points out that lung closes fur at body. When the function of lung is normal, lung yin is full, and normal lung-QI is peaceful, body fluid abundance,Energy compress must be capable, and skin metabolism product is excreted, and makes skin cleaning, naturally shines gloss. Permitted therefore have from ancient times to the presentMany doctors, recipe have from lung opinion to be controlled, and we think, and traditional Chinese medicine look effect is relevant, the corresponding theory of people and the world is traditional Chinese therapeuticsOne of characteristic, lung governing skin and hair, corresponding with white, this is the rule of our prescription just.
The present invention's class face-beautifying oral liquid of dispelling, in side, great burdock achene can stimulate circulation, prevention cardiovascular disease, great burdock achene extractsThing has very strong removing free radical and antioxidation, the synthetic collagen of yellow glucoside, amino acid and amino acid in great burdock acheneComposition is improved looks to human body, and check melanin growth keeps skin gloss and elasticity to play no small effect; The bighead atractylodes rhizome, enters taste warp,There is air making-up and spleen enlivening, eliminating dampness Li Shui, beauty treatment benefit flesh, the effect of promoting longevity. Modern pharmacology research shows: the bighead atractylodes rhizome, and containing volatile oil1.4%, principal component is atractylol (alcohol radical hydrolysis generates lipid), atractylone, and containing vitamin A. The root of Dahurain angelica, have promoting the circulation of qi fall apart blood, dispelEffect of wind dehumidifying, swelling and pain relieving, skin moistening and itch stopping. Shennong's Herbal carries: " longue skin, moist color, can make face fat ". Song" all book on Chinese herbal medicine of large China's tomorrow " carries: " remove the black dry flaw of face, broken place blood, mends new blood ". Modern pharmacology research shows that the root of Dahurain angelica containsYellow volatile oil 0.24%; Byak-angelicin, Byakangelicol (containing multiple hydroxyl constituents). The root of Dahurain angelica activates in high concentration, low concentrationThere is inhibitory action. Kaladana has the merit of skin care, happy look nti-freckle. " Classified Materia Meidca " said: " the main Yue Ze, good face, beneficial gas of making usDo not want, clothes are made light of one's life by commiting suicide and are endured hardships for a long time, and available fat makes the happy pool of face ". Modern pharmacological research shows: kaladana is containing saponin 0.68%, fatFat, uremic, citrulling etc., have the inorganic elements such as component and selenium that suppresses tryptose vigor, have immunologic enhancement. Sweet apricotBenevolence, have relieving cough and asthma, relax bowel, happy damp appearance, except the black dry merit that brightens, dispellings wind and arresting itching. As " Jing Yue's complete work. book on Chinese herbal medicineJust " carry: " especially kill parasites, the black dry Epileptic of tooth worm and women's head-ornaments looks into suitcase ". Modern pharmacological research represents: dessert almond, fatty oil is (sweetApricot kernel oil) 50%, containing bitter dessert almond glucoside approximately 3%, protein and various free amino acid. Bitter Semen pruni armeniacae extract is removed amino acidAfter, can make dessert almond honey, Glycerin, makes skin delicate glossy, is a kind of superior cosmetics spices. Full side is by burdockThe compositions such as son, the bighead atractylodes rhizome, the root of Dahurain angelica, dessert almond, kaladana, have do, the preserve youthful looks effect of happy look of profit skin, de-black.
Chloasma, chloasma hepaticum are a kind of facial metabolism of pigment obstacle dermatosis that is common in, and are apt to occur in female middle-aged, itsThe cause of disease and pathogenesis are illustrated not yet completely. It is generally acknowledged morbidity and the endocrinopathy of chloasma, ultraviolet ray irradiate, hereditary because ofHave pass. But research in recent years thinks, the generation of chloasma, chloasma hepaticum also changes relevant with oxygen radical. In normal physiological situationUnder, free radical constantly produces, but is also constantly eliminated, and makes it in a kind of dynamic equilibrium. And chloasma, chloasma hepaticum patient peroxidatingWhen lipid (LPO) or Free Radical Level increase, or in body, antioxidase is as superoxide dismutase (SOD), catalase(CAT), the decline such as glutathione (CSH), can not remove in time the oxidation products such as lipid peroxide, LPO is piled up in vivo. FromAnd acceleration tyrosine series oxidation reaction. Blackening chromatophore produces melanin to be increased; Simultaneously extremely unstable its product of LPO the third twoIt is crosslinked that aldehyde (MDA) can cause protein molecule to occur, and forms fluorescent chromophore-pigment.
Chloasma, chloasma hepaticum are the diseases that long-term factors causes. The activity of skin tyrosinase declines, and melanin is thinEndosome quantity increases, and wherein oxygen radical is one of major reason of chloasma formation. Most important in body antioxidant systemBe the effect of antioxidase, wherein SOD is one of topmost enzyme. This result of study shows after modeling, animal skin and liverThe MDA content of tissue improves, and SOD content reduces, with normal group comparing difference highly significant (P < 0.01). After treatment, MDA containsAmount decreases, and SOD content increases, with model group comparison, and significant difference (P < 0.05, P < 0.01); Wherein, heavy doseTreatment group and positive controls comparing difference be (P < 0.05) significantly. Point out thus spot-removing beautifying face oral liquid of the present invention can remove oxygenFree radical also reduces free-radical generating; Histopathology is observed and is shown that it can obviously improve histiocytic pathological change, alleviatesEpithelial hyperplasia, alleviates the little blood vessel dilatation of skin corium, reduces inflammatory cell number; It can obviously reduce SABC detection displayMelanin positive cell number and optical density in epithelial layer. Show that spot-removing beautifying face oral liquid has freckle removing and whitening effect.

Claims (10)

1. a great burdock achene beauty treatment and eliminating spot oral liquid, is characterized in that, described great burdock achene beauty treatment and eliminating spot oral liquid is by following weightThe bulk drug of part is made: 10～50 parts of great burdock achenes, and 10～20 parts of radix polygonati officinalis, 10～20 parts of dragon's blood, 10～20 parts of Radix Angelicae Sinensis, pseudo-ginseng 10～20 parts, 10～20 parts of bletillas, 10～20 parts, Poria cocos, 10～20 parts of the reds sage root, 10～20 parts of raspberries, 10～20 parts of dessert almonds, mulberry10～20 parts of white skins, 10～20 parts of sealworts, 10～20 parts of root tubers of aromatic turmeric, 10～20 parts of rhizoma cyperis, 10～20 parts of the Radixs Astragali, heart of a lotus seed benevolence 10～20Part, 10～20 parts of the bighead atractylodes rhizomes, 10～20 parts of Flos Albiziaes, 10～20 parts of motherworts, 10～20 parts of reticulate millettias, 10～20 parts of the larva of a silkworm with batrytis,10～20 parts of the fruit of glossy privets, 10～20 parts of the roots of Dahurain angelica, 10～20 parts of kaladanas.
2. great burdock achene beauty treatment and eliminating spot oral liquid according to claim 1, is characterized in that, described great burdock achene beauty treatment and eliminating spot is oralIn liquid, the parts by weight of various bulk drugs are: 10～30 parts of great burdock achenes, and 10～15 parts of radix polygonati officinalis, 10～15 parts of dragon's blood, Radix Angelicae Sinensis 10～15 parts, 10～15 parts of pseudo-ginseng, 10～15 parts of bletillas, 10～15 parts, Poria cocos, 10～15 parts of the reds sage root, 10～15 parts of raspberries, sweet apricot10～15 parts of benevolence, 10～15 parts of the root barks of white mulberry, 10～20 parts of sealworts, 10～20 parts of root tubers of aromatic turmeric, 10～20 parts of rhizoma cyperis, the Radix Astragali 10～20Part, 10～20 parts of heart of a lotus seed benevolence, 10～20 parts of the bighead atractylodes rhizomes, 10～20 parts of Flos Albiziaes, 10～20 parts of motherworts, 10～20 parts of reticulate millettias, white10～20 parts of stiff silkworms, 10～20 parts of the fruit of glossy privets, 10～20 parts of the roots of Dahurain angelica, 10～20 parts of kaladanas.
3. great burdock achene beauty treatment and eliminating spot oral liquid according to claim 1, is characterized in that, described great burdock achene beauty treatment and eliminating spot is oralThe ratio of weight and number of various bulk drugs in liquid: 10～40 parts of great burdock achenes, 10～20 parts of radix polygonati officinalis, 10～20 parts of dragon's blood, Radix Angelicae Sinensis 10～20 parts, 10～20 parts of pseudo-ginseng, 10～20 parts of bletillas, 10～20 parts, Poria cocos, 10～20 parts of the reds sage root, 10～20 parts of raspberries, sweet apricot10～20 parts of benevolence, 10～20 parts of the root barks of white mulberry, 10～20 parts of sealworts, 10～20 parts of root tubers of aromatic turmeric, 10～20 parts of rhizoma cyperis, the Radix Astragali 10～20Part, 10～20 parts of heart of a lotus seed benevolence, 10～20 parts of the bighead atractylodes rhizomes, 10～20 parts of Flos Albiziaes, 10～20 parts of motherworts, 10～20 parts of reticulate millettias, white10～20 parts of stiff silkworms, 10～20 parts of the fruit of glossy privets, 10～20 parts of the roots of Dahurain angelica, 10～20 parts of kaladanas.
4. a preparation method for great burdock achene beauty treatment and eliminating spot oral liquid as described in claim 1～3 any one, its feature existsIn, the preparation process of described great burdock achene beauty treatment and eliminating spot oral liquid comprises following aspect:
A. the frying of great burdock achene;
B. the extraction of great burdock achene;
C. surplus stock medicine is extracted;
D. the liquid again surplus stock medicine being extracted is concentrated;
E. concentrated medicament is mixed with the great burdock achene extract preparing, sterilizing, adds dextrin seasoning and is prepared into oral liquid.
5. the preparation method of great burdock achene beauty treatment and eliminating spot oral liquid according to claim 4, is characterized in that, in described step a,Get the great burdock achene obtaining and clean, the airing time, at 7-12 hour, parches; The good great burdock achene of airing is put into the pot that completesGreen grass or young crops, the 30-45 minute that completes at 80-100 DEG C, then puts into large iron pan and stir-fries, first backward upper downwards, firmly wants allEven, when great burdock achene color starts blackout, start the moulding in 30-45 minute that stir-fries of little fire; In the time that color becomes pitchy, take out certainly rearSo dry.
6. the preparation method of great burdock achene beauty treatment and eliminating spot oral liquid according to claim 4, is characterized in that, in described step b,Further comprise the good great burdock achene of frying is put into 10 times of amount ethanol, heating and refluxing extraction 2 times, each 1～2 hour, by 2 timesExtract merges standing; The great burdock achene dregs of a decoction of more above-mentioned alcohol extract being crossed add 10 times of water gaging heating and refluxing extraction 2 times, each 1～2 hours, No. 2 extracts are merged and left standstill; Above-mentioned two kinds of extracts are merged, and after recovery ethanol, reducing pressure, it is dense to put into inspissatorContracting, adjusts proportion to 1.06 by gained concentrate, and decompression recycling ethanol, obtains great burdock achene extract.
7. the preparation method of great burdock achene beauty treatment and eliminating spot oral liquid according to claim 4, is characterized in that, in described step c,Surplus stock medicine is cleaned to impurity elimination, dry, be ground into particle, soak 1 hour; Soaked bulk drug is put to Multifunction handGet boiling secondary in tank; Add up for the first time the water of 10 times of amounts of medicinal material, decoct 1.5～2 hours, get decocting liquid, filter; For the second timeAdd the water of 7 times of amounts of total amount, decoct 1～1.2 hour, get twice decocting liquid and mix, filter.
8. the preparation method of great burdock achene beauty treatment and eliminating spot oral liquid according to claim 4, is characterized in that, in described steps d,The filtrate of filtration is inserted in economic benefits and social benefits vacuum concentrator, and the concentrate that while being concentrated into 90 DEG C, relative density is 1.05, sets to 0～5 DEG CDeepfreeze 24 hours; Refrigeration liquid is added to 0.3% filter aid diatomite, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again,Be concentrated into every 1ml containing 1g crude drug amount, for subsequent use.
9. the preparation method of great burdock achene beauty treatment and eliminating spot oral liquid according to claim 4, is characterized in that, in described step e,Great burdock achene extract is mixed with surplus stock medicament extracting solution, add dextrin seasoning, ultraviolet disinfection, packs and get final product.
10. a preparation method for basis great burdock achene beauty treatment and eliminating spot oral liquid as described in claim 1～3 any one, its spyLevy and be, the preparation method of described great burdock achene beauty treatment and eliminating spot oral liquid comprises: great burdock achene good frying and surplus stock medicine are putEnter in 10 times of water gagings and soak; Then drop into multi-function extractor and extract twice, add for the first time 8-10 times of water gaging and decoct 1-2 hour,Add for the second time 4-8 times of water gaging and decoct 1-2 hour, merge twice decocting liquid, filter to get filtrate; Heating is concentrated into pasty state, adds dextrin and adjustsWith, canned after ultraviolet radiation for sterilizing and disinfecting.
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CN105166886A (en) * 2015-08-14 2015-12-23 殷永洲 Beauty-maintaining and young-keeping health-preserving granules
CN105079471A (en) * 2015-08-17 2015-11-25 俸莲英 Aesthetic health care beverage and preparation method thereof
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