CN104825379A - Whitening peeling night cream capable of reducing melanin deposition and preparation method thereof - Google Patents

Whitening peeling night cream capable of reducing melanin deposition and preparation method thereof Download PDF

Info

Publication number
CN104825379A
CN104825379A CN201510292518.1A CN201510292518A CN104825379A CN 104825379 A CN104825379 A CN 104825379A CN 201510292518 A CN201510292518 A CN 201510292518A CN 104825379 A CN104825379 A CN 104825379A
Authority
CN
China
Prior art keywords
minute
whitening
skin
thallus
late frost
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510292518.1A
Other languages
Chinese (zh)
Inventor
张忠
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JINAN FANGYU CULTURE MEDIA Co Ltd
Original Assignee
JINAN FANGYU CULTURE MEDIA Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JINAN FANGYU CULTURE MEDIA Co Ltd filed Critical JINAN FANGYU CULTURE MEDIA Co Ltd
Priority to CN201510292518.1A priority Critical patent/CN104825379A/en
Publication of CN104825379A publication Critical patent/CN104825379A/en
Pending legal-status Critical Current

Links

Abstract

The invention discloses whitening peeling night cream capable of reducing melanin deposition and a preparation method thereof. The whitening peeling night cream comprises, by weight, 20-30 parts of lycopene, 5-15 parts of bezoar, 5-15 parts of aloe, 6-16 parts of kelp, 10-20 parts of cucumber, 15-25 parts of chamomile, 6-10 parts of green tea extract, 8-20 parts of lettuce extract, 10-15 parts of vitamin E, 2-6 parts of glycerin and 5-9 parts of astaxanthin. The whitening peeling night cream has the advantages of having no stimulation and good effect and being easily acceptable to patients, and is prepared by adopting common local Chinese raw materials as raw materials and via a special processing technology.

Description

Reduce the whitening of melanin deposition to shine skin late frost and preparation method thereof
Technical field
The present invention relates to traditional Chinese medicine field, especially relate to a kind of whitening reducing melanin deposition and to shine skin late frost and preparation method thereof.
Background technology
Melanin is a kind of biochrome, and be that tyrosine or 3,4-dihydroxy phenylpropyl alcohol ammonia formed through a succession of chemical reaction, animal, plant and protista have this pigment.Melanin normally exists in the mode of polymerization.Melanin is the pigment of a kind of pitchy existed in animal skin or hair, is generated by a kind of special cell and melanocyte and is stored in wherein.Just because of melanic existence, skin has just had color.Once melanin can not be formed under certain reason, also just cause depigmentation, thus define white macula.Melanin is a kind of protein in fact, has in everyone body.20-25 year be melanin deposition formed active phase.In the middle of the cell that they are present in skin base layer, but a kind of material being " melanogen biomass ", be also called " chromoplast ".Chromoplast secretion Mai Laning pigment; when ultraviolet (B ripple, E ripple) is irradiated to (B ripple and UVB act on skin base layer) on skin; skin will be in the state of " self-protection "; Mai Laning pigment is stimulated by ultraviolet; activate the activity of tryrosinase, protect our Skin Cell.DOPA is exactly melanic predecessor in fact, forms through oxidizing tyrosine, discharges melanin.Melanin moving layer by layer again via cellular metabolism, has arrived skin epidermal area and has formed the shapes such as freckle, sunburn, black speck.
The face origin cause of formation: sunlight comprises luminous ray, infrared ray, ultraviolet, wherein UVC(the shortest ultraviolet) to the DNA (deoxyribonucleic acid) (DNE) in human body cell, there is injury effect, if long-term irradiation ultraviolet, dermatosis, skin carcinoma etc. can be obtained, serious meeting causes gene mutation, and general gene mutation is all pernicious.So Skin Cell physiologically will discharge melanin, melanin effectively can absorb ultraviolet, reduces ultraviolet to the impact of human body.Ultraviolet affects: when contact skin ultraviolet, will produce a kind of brown pigment being Mai Laning, and Mai Laning effect originally protects skin from uv damage, but after its protection task completes, will become dirt and peel off.When body metabolism is not good enough, partial pigment can stay skin surface, forms black speck.Lipid peroxide: Skin Cell is especially easily oxidized after being subject to ultraviolet radiation, can manufacture a kind of harmful substance being lipid peroxide, this material can damage skin corium equally, easily causes mottle.Live irregular: pressure, monophagia, the bad life habits such as not have enough sleep, also can make melanin increase.When evening 10 and morning 6 time be metabolic preferably opportunity, so the length of one's sleep instability people, the metabolic rate of skin is not good yet, can manufacture melanin.Endocrine disturbance: the lutein produced during menstrual period and During Pregnancy make endocrine especially easily lack of proper care is the peak period that melanin produces.Maintain normal living habit, avoid contact ultraviolet side to be very wise move.Diet key element: vitamin C and vitamin E are the nutritional factorss the most effectively improving black speck, existing prevention has again vat black pigment effect, also can help collagen growth, Glycerin, and play antioxidation, prevention skin premature aging.PM2.5: haze mainly comprises sulfur dioxide, nitrogen oxide and pellet.After sulfur dioxide and nitrogen oxide combine, the pore of skin will be invaded, react and cause melanic accumulation, mottle precipitation etc.The food supplemented containing vitamin D, beta glucan can promote skin metabolism more, prevention melanin deposition.
In the melanic patent of existing minimizing; application publication number CN 104288690 E(application number 201410548476.9) one treats melanomatous Chinese medicinal ointment, it is characterized in that: its raw material raw material respectively: Rhizoma Curcumae 100 parts, Calculus Bovis 50 parts, Borneolum Syntheticum 40 parts, Rhizoma Coptidis 90 parts, Radix Polygoni Multiflori 30 parts, Radix Gentianae 6 parts, Caulis Akebiae 6 parts, Herba Artemisiae Scopariae 15 parts, 10 parts, Talcum, 6 parts, Radix Glycyrrhizae.Application publication number CN 104138539 E(application number 201410322218.9) a kind of melanin cup fungi that patent discloses produce the composite LINGZHI JIAONANG of melanin, it is characterized in that being made up of the raw material of following weight portion: gelatine capsule shell 3-5, auxiliary agent 4-5 and appropriate water that Ganoderma 80-100, melanin preparation 2-3, Succus Momordicae charantiae 10-14, Radix Ginseng 6-8, Flos Matricariae chamomillae 4-5, Rhizoma Atractylodis Macrocephalae 7-10, leaf of Rhizoma Coptidis 4-6, Semen Crataegi 2-3, Stigma Maydis 6-8, food grade are medicinal; Described auxiliary agent has the raw material of following weight portion to make: leaf of Cerasus humilis Bunge 4-6, Flos Campsis 5-7, Ramulus Cinnamomi 14-18, Fructus Linderae 8-10, Flos Rosae Rugosae 5-7, Flos Lonicerae 5-6, Semen Armeniacae Amarum powder 25-30, Radix Notoginseng 12-15, Radix Angelicae Sinensis 6-8, wheat stalk 4-6, Caulis et Folium Chrysanthemi segeti 4-5, Folium Nelumbinis 6-7 and appropriate water; Preparation method is: (1) mixing leaf of Cerasus humilis Bunge, Flos Campsis, Fructus Linderae, Flos Rosae Rugosae, Flos Lonicerae and Caulis et Folium Chrysanthemi segeti, add 1.5-2.5 doubly to the water of cumulative volume, decocts to boil 60-70min to little fire after boiling and must concentrate decoction, filters to obtain decoction; (2) decoction will (1) be added after Semen Armeniacae Amarum powder parch 3-5min obtaining, furnishing pasty state; (3) mix Ramulus Cinnamomi, Radix Notoginseng, Radix Angelicae Sinensis, wheat stalk and Folium Nelumbinis, added water after not having material 6-8cm and boil, stifling pasty state Semen Armeniacae Amarum powder described in (2), continues 30-40min, completes after bake dry doubling and pulverize and get final product simultaneously.
Summary of the invention
For the reason that above-mentioned melanin difference is formed, an object of the present invention is to provide a kind of whitening reducing melanin deposition to shine skin late frost, have non-stimulated, effective, feature easy to patients, the present invention adopts middle raw material comparatively common in the localities as raw material, forms through special processing technique manufacture.
Another object of the present invention is just to provide above-mentioned whitening and shines the preparation method of skin late frost.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Reduce the whitening of melanin deposition to shine skin late frost, the weight proportion of each crude drug is as follows, is weight portion:
Lycopene 20-30 Calculus Bovis 5-15 Aloe 5-15
Thallus Laminariae (Thallus Eckloniae) 6-16 Fructus Cucumidis sativi 10-20 Flos Matricariae chamomillae 15-25
Green tea extract 6-10 Caulis et Folium Lactucae sativae extract 8-20 vitamin e1 0-15
Glycerol 2-6 astaxanthin 5-9.
The whitening of aforementioned minimizing melanin deposition shines skin late frost, preferred scheme, and the weight proportion of each crude drug is as follows, is weight portion:
Lycopene 23-28 Calculus Bovis 8-13 Aloe 8-13
Thallus Laminariae (Thallus Eckloniae) 10-12 Fructus Cucumidis sativi 13-18 Flos Matricariae chamomillae 18-23
Green tea extract 7-9 Caulis et Folium Lactucae sativae extract 14-16 vitamin e1 1-14
Glycerol 3-5 astaxanthin 6-8.
The whitening of aforementioned minimizing melanin deposition shines skin late frost, better preferred scheme, and the weight proportion of each crude drug is as follows, is weight portion:
Lycopene 25 Calculus Bovis 11 Aloe 10
Thallus Laminariae (Thallus Eckloniae) 11 Fructus Cucumidis sativi 15 Flos Matricariae chamomillae 20
Green tea extract 8 Caulis et Folium Lactucae sativae extract 15 vitamin e1 3
Glycerol 4 astaxanthin 7.
Reduce the whitening of melanin deposition to shine the preparation method of skin late frost, step is as follows:
(1) Thallus Laminariae (Thallus Eckloniae) is eluriated 3-7 time, with the hot-water soak 10-14 of 90-100 DEG C hour, in the process of soaking, add Thallus Laminariae (Thallus Eckloniae) weight 0.2-0.6 Pericarpium Citri Reticulatae doubly, soak well and take out Thallus Laminariae (Thallus Eckloniae), be cut into filament, be placed in baking box roasting after 5-12 minute, it is stand-by to grind to form smalls;
(2) dispelled by Aloe thorn, break into the block of size as nail cover, be placed in the slender roll of medicated paper or gauze, be ground into thick liquid, be placed in close grenadine cloth, discharge by pressing filtrate, filtrate is stand-by, and filtering residue is placed on iron plate, dries 2-6 minute to obtain smalls;
(3) Fructus Cucumidis sativi is cut into the fritter of beans size, is placed in the slender roll of medicated paper or gauze, is ground into thick liquid, be placed in close grenadine cloth, discharge by pressing filtrate, filtrate is stand-by, and filtering residue is placed on iron plate, dry 3-7 minute smalls to cross 80-120 mesh sieve stand-by;
(4) Calculus Bovis and Flos Matricariae chamomillae are cleaned, chopping, the intense fire that adds water is fried open, and after boiling 1-5 minute, turns slow fire boiling 20-40 minute, and filter, filtrate leaves standstill 24-48 hour, gets supernatant stand-by;
(5) step (4) gained supernatant is placed in clean container; add lycopene, green tea extract, Caulis et Folium Lactucae sativae extract, vitamin E and astaxanthin; decoct while be stirred to crude drug and melt completely; step (1)-(3) gained smalls is added after melting completely; cease fire and add step (2)-(3) gained filtrate and glycerol; abundant stirring 2-6 minute, sterilizing 1-5 minute at 120-140 DEG C, bottles and get final product.
Above-mentioned whitening shone the preparation method of skin late frost, and step (1) Thallus Laminariae (Thallus Eckloniae) eluriates 4-6 time, with the hot-water soak 11-13 of 93-98 DEG C hour (preferred, Thallus Laminariae (Thallus Eckloniae) eluriates 5 times, the hot-water soak 12 hours with 95 DEG C).
Above-mentioned whitening shines the preparation method of skin late frost, step (1) adds Thallus Laminariae (Thallus Eckloniae) weight 0.3-0.5 Pericarpium Citri Reticulatae doubly in the process of soaking, soak well and take out Thallus Laminariae (Thallus Eckloniae), be cut into filament, be placed in baking box to bake after 7-10 minute and (preferably, in the process of soaking, add the Pericarpium Citri Reticulatae of Thallus Laminariae (Thallus Eckloniae) weight 0.4 times, after immersion is good, take out Thallus Laminariae (Thallus Eckloniae), be cut into filament, be placed in baking box roasting after 8 minutes).
Above-mentioned whitening shines the preparation method of skin late frost, and step (2) filtering residue is placed on iron plate, dries 3-5 minute to obtain smalls (preferred, filtering residue is placed on iron plate, and drying 4 minutes must smalls).
Above-mentioned whitening shines the preparation method of skin late frost, step (3) dry 4-6 minute smalls cross 90-110 mesh sieve stand-by (preferred, dries 5 minutes must smalls to cross 100 mesh sieves stand-by).
Above-mentioned whitening shines the preparation method of skin late frost, and step (4), after boiling 2-4 minute, turns slow fire boiling 25-35 minute, filters, and filtrate leaves standstill 30-40 hour (preferred, until boiling after 3 minutes, turn slow fire boiling 30 minutes, filter, filtrate leaves standstill 35 hours).
Above-mentioned whitening shines the preparation method of skin late frost, and step (5) fully stirs 3-5 minute, at 125-135 DEG C sterilizing 2-4 minute (preferred, fully to stir 4 minutes, sterilizing 3 minutes at 130 DEG C).
For making this medicine reach optimum therapeuticing effect, face cleans up before sleep by every night, spreads upon on the face by gained late frost, under clapping 20-30, is placed in the cold preservation of refrigerator evening after being finished with have gentle hands.
This whitening shines skin late frost to minimizing melanin deposition Be very effective, has rapid-action, the feature that cure rate is high, uses this whitening skin late frost that shines to have not a particle of uncomfortable sensation, the local common raw materials of multiselect of the present invention, cheap, alleviates the financial burden of patient.
The pharmacological effect of each crude drug is respectively:
Lycopene: be a kind of natural pigment contained in plant.Mainly be present in the mature fruit of plant of Solanaceae Fructus Lycopersici esculenti.It is one of most powerful antioxidant be found in natural plant at present.Science proves, the singlet oxygen in human body and oxygen-derived free radicals are the arch-criminals of infringement human body self immune system.Effect of lycopene scavenging free radicals outclass other carotenoid and vitamin E, and its singlet-oxygen quenching speed constant is 100 times of vitamin E.It can effectively preventing because of aging, the various diseases that immunity degradation causes, ultra-violet radiation resisting function: lycopene can to ultraviolet injury resistant.Research worker give 10 Healthy Peoples each supplement 28 milligrams of beta-carotene and 2 milligrams lycopene 1-2 month, result takes the area minimizing that lycopene crowd ultraviolet causes erythema, degree alleviates, slow down aging, enhancing immunity: lycopene can remove the free radical in human body most effectively, keep cell homergy, anti-aging in advance.Lycopene is absorbed by gastrointestinal mucosal in vivo and enters blood and lymph, be distributed to testis, adrenal gland, prostate, pancreas, breast, ovary, liver, lung, colon, skin and various mucosal tissue, promote glandular secretion hormone, thus make the energy that human body keeps vigorous; Remove the free radical in these Organ and tissues, protect them to escape injury, enhancing human body immunity power.India scholar points out, lycopene can make the increase of Infertil man sperm quantity, vigor strengthens, thus cures sterile problem.Lycopene can improve skin allergy greatly, eliminates the xerosis cutis and scratchiness that cause because of skin allergy, makes us feeling relaxed happiness.
Calculus Bovis: Calculus Bovis gas delicate fragrance, mildly bitter flavor is then sweet, cool in nature.Can be used for antipyretic, removing toxic substances, arresting convulsion.The disease such as Zhi Gaore coma for oral administration, demented, infantile convulsion, tic, external is controlled laryngopharynx swelling and pain, aphtha carbuncle, is treated toxication, and clear away heart-fire, eliminating phlegm, has one's ideas straightened out, cool liver, endogenous wind stopping, removing toxic substances.For calentura coma, middle wind-phlegm fan, infantile convulsion is twitched, and epilepsy is gone mad, laryngopharynx swelling and pain, aphtha of the mouth and tongue, carbuncle furuncle.
Aloe: the polysaccharide contained in Aloe and multivitamin have good nutrition, moist, whitening effect to human body skin.Aloe Barbadensis Miller is the Fresh leaf of aloe that optimum is directly improved looks, i.e. Aloe vulgaris, and it has the performance making skin contraction, softnessization, moisturizing, antiinflammatory, bleaching.Remove sclerosis, keratinization in addition, improve the effect of scar, little wrinkle, eye pouch, cutis laxa can not only be prevented, skin wet, tender and lovely can also be kept, simultaneously, can also scytitis be treated, also have good curative effect to acne, freckle, acne and scald, knife injury, insect bite etc.Effective too to hair, hair can be made to keep moistening smooth, pre-Anti-hair loss.
Thallus Laminariae (Thallus Eckloniae): the extract laminarin of Thallus Laminariae (Thallus Eckloniae) has radiation resistance because of Immunosuppression apoptosis, also close fatty acid and dietary fiber containing a large amount of insatiable hungers in Thallus Laminariae (Thallus Eckloniae), it can remove rapidly cholesterol unnecessary on vascular wall, and helps gastric juice to secrete, reach the object of digestion, enterogastric peristalsis is had very great help, well-known Thallus Laminariae (Thallus Eckloniae), not only nutritive value is quite high, except containing multivitamin, outside cellulose and mineral, and, still prevent and treat good medicine strumous.Iodine in Thallus Laminariae (Thallus Eckloniae) is very abundant, and this element is the primary raw material of synthetic thyroid element in body.And the gloss of hair is supported due to thyroxine in body and is played a role and formed." hair quality " and contained cutin composition, will draw from the protein of sulfur-bearing, and protein is the important substance making hair produce gloss.Except containing except iodine, calcium, sulfur in Thallus Laminariae (Thallus Eckloniae), also containing ferrum, sodium, magnesium, potassium, cobalt, phosphorus, mannitol and the many kinds of substance such as vitamin B1, B2, C.These nutrients are all of great advantage to hair caring.Therefore, often eat Thallus Laminariae (Thallus Eckloniae), all have special effect to the growth of hair, moist, pitch-black, light, kelp Rich, containing calcium constituent and I, contributes to thyroxine synthesis, and these two kinds of elements collocation, can not only improve looks, also have the effect of slow down aging.
Fructus Cucumidis sativi: toxicity: toxicity is lower.Nature and flavor: sweet in the mouth; Cool in nature.Gui Jing: return lung; Spleen; Stomach warp.Function cures mainly: heat clearing away; Diuretic; Removing toxic substances.Main calentura is thirsty; Oliguria with reddish urine; Edema oliguria; Burn due to hot liquid or fire; Tinea versicolor; Non-skin ulcer, 1, antitumor
The cucurbitacin C contained in Fructus Cucumidis sativi has the effect improving immune function of human body, reaches antitumor object.2, defying age: containing abundant vitamin E in Fructus Cucumidis sativi, can life lengthening be played, antidotal effect; Cucumber chitinase in Fructus Cucumidis sativi, has very strong biological activity.3, to lose weight strong body: hydroxymalonic acid contained in Fructus Cucumidis sativi, glucide can be suppressed to change fat into.4, invigorating brain and relieving mental uneasiness: Fructus Cucumidis sativi contains vitamin B1, to improving brain and nervous function is favourable, can tranquilizing the mind.5, alcoholism is prevented: alanine, arginine and glutamine contained in Fructus Cucumidis sativi, to liver patient, particularly have certain auxiliary therapeutic action to alcoholic cirrhosis patient, can prevent and treat alcoholism.6, blood glucose is reduced: glycoside, fructose etc. contained in Fructus Cucumidis sativi do not participate in common carbohydrate metabolism, therefore diabetes patient allays one's hunger for starch food with Fructus Cucumidis sativi, not only blood glucose can not raise, and even can reduce.。
Flos Matricariae chamomillae: skin care: improve acne, allergy, eczema, burn and scald, can say it is one of best quintessence oil of skin; Women takees good care of: improve menstruation and have some setbacks, menstrual pain; Health is takeed good care of: headache, otalgia, toothache, abdominal pain diarrhea, flatulence, muscular soreness.Skin nursing: fabulous to dryness, sensitive skin; Good effect is had to treatment pimples, herpes, eczema, tinea, microvascular; Can be used for protecting the most responsive eye skin of face, bring that to make eye cream also good.Skin basic nursing: whole body smears wiping.
Green tea extract: [effect for reducing blood fat]: tea polyphenols obviously can reduce serum total cholesterol, triglyceride, the low-density lipoprotein cholesterol content of hyperlipemia, has the effect recovering and protect vascular endothelial function simultaneously.The effect for reducing blood fat of tea polyphenols is also that Folium Camelliae sinensis can make overweight people lose weight the one of the main reasons do not rebounded.[antioxidation]: tea polyphenols lipid peroxidation process capable of blocking, improves the activity of human enzymes, thus plays effect of mutation, anticancer.[function of tumor inhibition]: tea polyphenols can the synthesis of inhibition tumor cell DNA, lures that mutant DNA ruptures into, thus can the synthetic ratio of inhibition tumor cell, the propagation of the growth of further Tumor suppression.[disinfecting detoxifying effect]: tea polyphenols can kill bacillus botulinus and spore, the ectotoxic activity of anti-bacteria.Antibacterial action is had to causing the various pathogen of diarrhoea, respiratory tract and skin infection.Tea polyphenols has obvious inhibitory action to causing pyogenic infection, burn, the staphylococcus aureus of wound, modification bacillus.[relieving the effect of alcohol and the liver protecting effect]: alcoholic liver injury is the radical damage that causes of ethanol mainly, tea polyphenols, as free radical scavenger, has the effect suppressing alcoholic liver injury.[detoxicating effect]: serious environmental pollution has obvious toxic action to health, tea polyphenols heavy metal has strong adsorption, can form complex with heavy metal and produce precipitation, is conducive to alleviating the toxic action that heavy metal produces human body.In addition, tea polyphenols also has the effect improving liver function and diuresis, thus has good anti-solution effect to alkaloid is poisoning.[raising immunity of organisms]: tea polyphenols, by improving human immunoglobulin total amount and making it maintain high level, stimulates the change of antibody activity, thus improves the overall immune ability of people, and can promote self conditioning functions of human body.
Caulis et Folium Lactucae sativae extract: sharp the five internal organs, qualcomm meridian, opens sharp chest and diaphragm.Plant gas, strengthening bone and muscle, remove halitosis, make teeth whiter, eyes are become clear.There is again the effect of lactogenic juice.Diuresis is drained, the poison that solution insect poison and Serpentis sting.
Vitamin E: be dissolved in the organic solvents such as fat and ethanol, water insoluble, heat, acid are stablized, unstable to alkali, responsive to oxygen, insensitive to heat, but time fried, Vitamin E activity obviously reduces.Tocopherol can promote sex hormones secretion, and man's motility of sperm and quantity are increased; Woman's estrogen concentration is increased, and improve fertility, prevention of miscarriage, also can be used for preventing and treating the aspects such as male infertility, burn, cold injury, capillary hemorrhage, climacteric syndrome, beauty treatment.Recently also find that vitamin E can suppress the lipid peroxidation in eye lens to react, and makes peripheral vasodilation, improves blood circulation, pre-Anti-myopic eye occurs and development.
Glycerol: food grade glycerol wherein optimum one-biology is refined glycerol, except containing glycerol, also has the reducing sugar such as esters, glucose, belongs to polyalcohols glycerol; Except there is moisturizing, humectation function, also there is the special efficacies such as high activity, antioxidation, short alcoholization.
Astaxanthin: defying age, antitumor, prevention cardiovascular and cerebrovascular disease, the Maintenance Of Skin Health, improve the effects such as motion function.
Whitening of the present invention shines the principle that skin late frost is formed based on melanin.The medicine of existing minimizing melanin deposition, food and plant in the raw material selected, there is again the crude drug reducing melanin deposition, the preparation cost invention together that cooperatively interacts of the crude drug of various effect to shine skin late frost for the whitening of external, has fabulous therapeutical effect to minimizing melanin deposition.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1reduce the whitening of melanin deposition to shine skin late frost, take off the crude drug stating weight proportion and be prepared from (getting 10g for every part):
Lycopene 20 Calculus Bovis 5 Aloe 5
Thallus Laminariae (Thallus Eckloniae) 6 Fructus Cucumidis sativi 10 Flos Matricariae chamomillae 15
Green tea extract 6 Caulis et Folium Lactucae sativae extract 8 vitamin e1 0
Glycerol 2 astaxanthin 5.
The whitening of above-mentioned minimizing melanin deposition shines the preparation method of skin late frost, and step is:
(1) Thallus Laminariae (Thallus Eckloniae) is eluriated 3 times, with the hot-water soak 10 hours of 90 DEG C, in the process of soaking, adds the Pericarpium Citri Reticulatae of Thallus Laminariae (Thallus Eckloniae) weight 0.2 times, soak good after take out Thallus Laminariae (Thallus Eckloniae), be cut into filament, be placed in baking box roasting after 5 minutes, it is stand-by to grind to form smalls;
(2) dispelled by Aloe thorn, break into the block of size as nail cover, be placed in the slender roll of medicated paper or gauze, be ground into thick liquid, be placed in close grenadine cloth, discharge by pressing filtrate, filtrate is stand-by, and filtering residue is placed on iron plate, dries 2 minutes to obtain smalls;
(3) Fructus Cucumidis sativi is cut into the fritter of beans size, is placed in the slender roll of medicated paper or gauze, is ground into thick liquid, be placed in close grenadine cloth, discharge by pressing filtrate, filtrate is stand-by, and filtering residue is placed on iron plate, dry 3 minutes smalls to cross 80 mesh sieves stand-by;
(4) Calculus Bovis and Flos Matricariae chamomillae are cleaned, chopping, the intense fire that adds water is fried open, and until boiling after 1 minute, turns slow fire boiling 20 minutes, filters, and filtrate leaves standstill 24 hours, gets supernatant stand-by;
(5) step (4) gained supernatant is placed in clean container; add lycopene, green tea extract, Caulis et Folium Lactucae sativae extract, vitamin E and astaxanthin; decoct while be stirred to crude drug and melt completely; step (1)-(3) gained smalls is added after melting completely; cease fire and add step (2)-(3) gained filtrate and glycerol; abundant stirring 2 minutes, at 120 DEG C, sterilizing 1 minute, bottles and get final product.
embodiment 2reduce the whitening of melanin deposition to shine skin late frost, take off the crude drug stating weight proportion and be prepared from (getting 15g for every part):
Lycopene 30 Calculus Bovis 15 Aloe 15
Thallus Laminariae (Thallus Eckloniae) 16 Fructus Cucumidis sativi 20 Flos Matricariae chamomillae 25
Green tea extract 10 Caulis et Folium Lactucae sativae extract 20 vitamin e1 5
Glycerol 6 astaxanthin 9.
The whitening of above-mentioned minimizing melanin deposition shines the preparation method of skin late frost, and step is:
(1) Thallus Laminariae (Thallus Eckloniae) is eluriated 7 times, with the hot-water soak 14 hours of 100 DEG C, in the process of soaking, adds the Pericarpium Citri Reticulatae of Thallus Laminariae (Thallus Eckloniae) weight 0.6 times, soak good after take out Thallus Laminariae (Thallus Eckloniae), be cut into filament, be placed in baking box roasting after 12 minutes, it is stand-by to grind to form smalls;
(2) dispelled by Aloe thorn, break into the block of size as nail cover, be placed in the slender roll of medicated paper or gauze, be ground into thick liquid, be placed in close grenadine cloth, discharge by pressing filtrate, filtrate is stand-by, and filtering residue is placed on iron plate, dries 6 minutes to obtain smalls;
(3) Fructus Cucumidis sativi is cut into the fritter of beans size, is placed in the slender roll of medicated paper or gauze, is ground into thick liquid, be placed in close grenadine cloth, discharge by pressing filtrate, filtrate is stand-by, and filtering residue is placed on iron plate, dry 7 minutes smalls to cross 120 mesh sieves stand-by;
(4) Calculus Bovis and Flos Matricariae chamomillae are cleaned, chopping, the intense fire that adds water is fried open, and until boiling after 5 minutes, turns slow fire boiling 40 minutes, filters, and filtrate leaves standstill 48 hours, gets supernatant stand-by;
(5) step (4) gained supernatant is placed in clean container; add lycopene, green tea extract, Caulis et Folium Lactucae sativae extract, vitamin E and astaxanthin; decoct while be stirred to crude drug and melt completely; step (1)-(3) gained smalls is added after melting completely; cease fire and add step (2)-(3) gained filtrate and glycerol; abundant stirring 6 minutes, at 140 DEG C, sterilizing 5 minutes, bottles and get final product.
typical case one:zhu XX, female, 29 years old, Distributions in Liaocheng of Shandong Province personage, is engaged in editing 3 years, and in this time in 3 years, every day almost will computer previous work 8 hours, nearest Mrs Zhu prepares to marry, go clap wedding photography, face and bad, the photo of take is very plain, female Zhu scholar have employed a lot of method and reduces melanin deposition, but effect is always bad, and more and more serious, gained whitening of the present invention is used to shine skin late frost after being introduced.
Use the whitening of embodiment 2 gained to shine skin late frost, face cleans up before sleep by every night, spreads upon on the face by gained late frost, under clapping 20-30 with have gentle hands, after being finished, is placed in the cold preservation of refrigerator in the evening, uses second day, sensation skin smooth is fine and smooth, do not have fuel-displaced when working on the face, continue use 7 days, skin is obviously pale, small pox also disappears, patient uses always, whitening skin, and radiation-proof effect is also fine.
embodiment 3:reduce the whitening of melanin deposition to shine skin late frost, take off the crude drug stating weight proportion and be prepared from (getting 20g for every part):
Lycopene 23 Calculus Bovis 8 Aloe 8
Thallus Laminariae (Thallus Eckloniae) 10 Fructus Cucumidis sativi 13 Flos Matricariae chamomillae 18
Green tea extract 7 Caulis et Folium Lactucae sativae extract 14 vitamin e1 1
Glycerol 3 astaxanthin 6.
The whitening of above-mentioned minimizing melanin deposition shines the preparation method of skin late frost, and step is:
(1) Thallus Laminariae (Thallus Eckloniae) is eluriated 4 times, with the hot-water soak 11 hours of 93 DEG C, in the process of soaking, adds the Pericarpium Citri Reticulatae of Thallus Laminariae (Thallus Eckloniae) weight 0.3 times, soak good after take out Thallus Laminariae (Thallus Eckloniae), be cut into filament, be placed in baking box roasting after 7 minutes, it is stand-by to grind to form smalls;
(2) dispelled by Aloe thorn, break into the block of size as nail cover, be placed in the slender roll of medicated paper or gauze, be ground into thick liquid, be placed in close grenadine cloth, discharge by pressing filtrate, filtrate is stand-by, and filtering residue is placed on iron plate, dries 3 minutes to obtain smalls;
(3) Fructus Cucumidis sativi is cut into the fritter of beans size, is placed in the slender roll of medicated paper or gauze, is ground into thick liquid, be placed in close grenadine cloth, discharge by pressing filtrate, filtrate is stand-by, and filtering residue is placed on iron plate, dry 4 minutes smalls to cross 90 mesh sieves stand-by;
(4) Calculus Bovis and Flos Matricariae chamomillae are cleaned, chopping, the intense fire that adds water is fried open, and until boiling after 2 minutes, turns slow fire boiling 25 minutes, filters, and filtrate leaves standstill 30 hours, gets supernatant stand-by;
(5) step (4) gained supernatant is placed in clean container; add lycopene, green tea extract, Caulis et Folium Lactucae sativae extract, vitamin E and astaxanthin; decoct while be stirred to crude drug and melt completely; step (1)-(3) gained smalls is added after melting completely; cease fire and add step (2)-(3) gained filtrate and glycerol; abundant stirring 3 minutes, at 125 DEG C, sterilizing 2 minutes, bottles and get final product.
embodiment 4reduce the whitening of melanin deposition to shine skin late frost, take off the crude drug stating weight proportion and be prepared from (getting 25g for every part):
Lycopene 28 Calculus Bovis 13 Aloe 13
Thallus Laminariae (Thallus Eckloniae) 12 Fructus Cucumidis sativi 18 Flos Matricariae chamomillae 23
Green tea extract 9 Caulis et Folium Lactucae sativae extract 16 vitamin e1 4
Glycerol 5 astaxanthin 8.
The whitening of above-mentioned minimizing melanin deposition shines the preparation method of skin late frost, and step is:
(1) Thallus Laminariae (Thallus Eckloniae) is eluriated 6 times, with the hot-water soak 13 hours of 98 DEG C, in the process of soaking, adds the Pericarpium Citri Reticulatae of Thallus Laminariae (Thallus Eckloniae) weight 0.5 times, soak good after take out Thallus Laminariae (Thallus Eckloniae), be cut into filament, be placed in baking box roasting after 10 minutes, it is stand-by to grind to form smalls;
(2) dispelled by Aloe thorn, break into the block of size as nail cover, be placed in the slender roll of medicated paper or gauze, be ground into thick liquid, be placed in close grenadine cloth, discharge by pressing filtrate, filtrate is stand-by, and filtering residue is placed on iron plate, dries 5 minutes to obtain smalls;
(3) Fructus Cucumidis sativi is cut into the fritter of beans size, is placed in the slender roll of medicated paper or gauze, is ground into thick liquid, be placed in close grenadine cloth, discharge by pressing filtrate, filtrate is stand-by, and filtering residue is placed on iron plate, dry 6 minutes smalls to cross 110 mesh sieves stand-by;
(4) Calculus Bovis and Flos Matricariae chamomillae are cleaned, chopping, the intense fire that adds water is fried open, and until boiling after 4 minutes, turns slow fire boiling 35 minutes, filters, and filtrate leaves standstill 40 hours, gets supernatant stand-by;
(5) step (4) gained supernatant is placed in clean container; add lycopene, green tea extract, Caulis et Folium Lactucae sativae extract, vitamin E and astaxanthin; decoct while be stirred to crude drug and melt completely; step (1)-(3) gained smalls is added after melting completely; cease fire and add step (2)-(3) gained filtrate and glycerol; abundant stirring 5 minutes, at 135 DEG C, sterilizing 4 minutes, bottles and get final product.
model case two:poplar XX, female, 35 years old, Jinan, Shandong Province personage, is engaged in the work 2 years of ultrasound diagnosis, and in this time in 2 years, every day almost will work 3-5 hour under the adjustment having radiation, nearest Mrs's Yang face very bad, small pox is also many, looks always a lot, fuel-displaced very serious, poplar female scholar have employed a lot of method and reduces melanin deposition, but effect is always bad, and more and more serious, gained whitening of the present invention is used to shine skin late frost after being introduced.
Use the whitening of embodiment 4 gained to shine skin late frost, face cleans up before sleep by every night, spreads upon on the face by gained late frost, under clapping 20-30 with have gentle hands, after being finished, is placed in the cold preservation of refrigerator in the evening, uses second day, sensation skin smooth is fine and smooth, do not have fuel-displaced when working on the face, continue use 7 days, skin is obviously pale, small pox also disappears, patient uses always, whitening skin, and radiation-proof effect is also fine.
embodiment 5:reduce the whitening of melanin deposition to shine skin late frost, take off the crude drug stating weight proportion and be prepared from (getting 30g for every part):
Lycopene 25 Calculus Bovis 11 Aloe 10
Thallus Laminariae (Thallus Eckloniae) 11 Fructus Cucumidis sativi 15 Flos Matricariae chamomillae 20
Green tea extract 8 Caulis et Folium Lactucae sativae extract 15 vitamin e1 3
Glycerol 4 astaxanthin 7.
The whitening of above-mentioned minimizing melanin deposition shines the preparation method of skin late frost, and step is:
(1) Thallus Laminariae (Thallus Eckloniae) is eluriated 5 times, with the hot-water soak 12 hours of 95 DEG C, in the process of soaking, adds the Pericarpium Citri Reticulatae of Thallus Laminariae (Thallus Eckloniae) weight 0.4 times, soak good after take out Thallus Laminariae (Thallus Eckloniae), be cut into filament, be placed in baking box roasting after 8 minutes, it is stand-by to grind to form smalls;
(2) dispelled by Aloe thorn, break into the block of size as nail cover, be placed in the slender roll of medicated paper or gauze, be ground into thick liquid, be placed in close grenadine cloth, discharge by pressing filtrate, filtrate is stand-by, and filtering residue is placed on iron plate, dries 4 minutes to obtain smalls;
(3) Fructus Cucumidis sativi is cut into the fritter of beans size, is placed in the slender roll of medicated paper or gauze, is ground into thick liquid, be placed in close grenadine cloth, discharge by pressing filtrate, filtrate is stand-by, and filtering residue is placed on iron plate, dry 5 minutes smalls to cross 100 mesh sieves stand-by;
(4) Calculus Bovis and Flos Matricariae chamomillae are cleaned, chopping, the intense fire that adds water is fried open, and until boiling after 3 minutes, turns slow fire boiling 30 minutes, filters, and filtrate leaves standstill 35 hours, gets supernatant stand-by;
(5) step (4) gained supernatant is placed in clean container; add lycopene, green tea extract, Caulis et Folium Lactucae sativae extract, vitamin E and astaxanthin; decoct while be stirred to crude drug and melt completely; step (1)-(3) gained smalls is added after melting completely; cease fire and add step (2)-(3) gained filtrate and glycerol; abundant stirring 4 minutes, at 130 DEG C, sterilizing 3 minutes, bottles and get final product.
experimental example (whitening of embodiment 5 gained shine skin late frost):in order to verify that whitening of the present invention shines the effect of skin late frost, we have extracted 400 patients in 4 hospitals and have carried out the experiment of medicine, test group 200 people, matched group 200 people, experimental group uses the whitening of embodiment 5 gained to shine skin late frost, and matched group uses other treatment to reduce the skin care item of melanin deposition.Inclusion criteria: through being diagnosed as melanin deposition patient, has melanin deposition clinical symptoms one or more.Using method: face cleans up before sleep by every night, spreads upon on the face by gained late frost, under clapping 20-30, is placed in evening in the cold preservation of refrigerator after being finished with have gentle hands.Curative effect situation criterion: 1, cure, after using this product, malaise symptoms disappears completely; 2, effective, after using this product, malaise symptoms alleviates or partial disappearance; 3, invalid, after using this product, malaise symptoms is unchanged.We have carried out accurate statistics and mathematical analysis to experimental data.Specific experiment result is as following table:
Table 1: two groups of Clinical efficacy comparison [example] tables 1
Whitening of the present invention shine skin late frost to treatment reduce melanin deposition have significant curative effect, melanin deposition patient in various degree can be treated, effective percentage is up to 99%, cure rate is up to 95%, severe patient shines skin late frost after 20 days in use gained whitening of the present invention, and symptom also can alleviate, and the whitening of this invention skin late frost that shines is cheap, evident in efficacy, the present invention is that a kind for the treatment of reduces the melanin deposition skin late frost and whitening without any side effects shines safely.

Claims (10)

1. reduce the whitening of melanin deposition to shine skin late frost, it is characterized in that: the weight proportion of each crude drug is as follows, is weight portion:
Lycopene 20-30 Calculus Bovis 5-15 Aloe 5-15
Thallus Laminariae (Thallus Eckloniae) 6-16 Fructus Cucumidis sativi 10-20 Flos Matricariae chamomillae 15-25
Green tea extract 6-10 Caulis et Folium Lactucae sativae extract 8-20 vitamin e1 0-15
Glycerol 2-6 astaxanthin 5-9.
2. the whitening of minimizing melanin deposition according to claim 1 shines skin late frost, it is characterized in that: the weight proportion of each crude drug is as follows, is weight portion:
Lycopene 23-28 Calculus Bovis 8-13 Aloe 8-13
Thallus Laminariae (Thallus Eckloniae) 10-12 Fructus Cucumidis sativi 13-18 Flos Matricariae chamomillae 18-23
Green tea extract 7-9 Caulis et Folium Lactucae sativae extract 14-16 vitamin e1 1-14
Glycerol 3-5 astaxanthin 6-8.
3. the whitening of minimizing melanin deposition according to claim 1 shines skin late frost, it is characterized in that: the weight proportion of each crude drug is as follows, is weight portion:
Lycopene 25 Calculus Bovis 11 Aloe 10
Thallus Laminariae (Thallus Eckloniae) 11 Fructus Cucumidis sativi 15 Flos Matricariae chamomillae 20
Green tea extract 8 Caulis et Folium Lactucae sativae extract 15 vitamin e1 3
Glycerol 4 astaxanthin 7.
4. the whitening of the minimizing melanin deposition according to any one of claim 1-3 shines the preparation method of skin late frost, it is characterized in that: step is as follows:
(1) Thallus Laminariae (Thallus Eckloniae) is eluriated 3-7 time, with the hot-water soak 10-14 of 90-100 DEG C hour, in the process of soaking, add Thallus Laminariae (Thallus Eckloniae) weight 0.2-0.6 Pericarpium Citri Reticulatae doubly, soak well and take out Thallus Laminariae (Thallus Eckloniae), be cut into filament, be placed in baking box roasting after 5-12 minute, it is stand-by to grind to form smalls;
(2) dispelled by Aloe thorn, break into the block of size as nail cover, be placed in the slender roll of medicated paper or gauze, be ground into thick liquid, be placed in close grenadine cloth, discharge by pressing filtrate, filtrate is stand-by, and filtering residue is placed on iron plate, dries 2-6 minute to obtain smalls;
(3) Fructus Cucumidis sativi is cut into the fritter of beans size, is placed in the slender roll of medicated paper or gauze, is ground into thick liquid, be placed in close grenadine cloth, discharge by pressing filtrate, filtrate is stand-by, and filtering residue is placed on iron plate, dry 3-7 minute smalls to cross 80-120 mesh sieve stand-by;
(4) Calculus Bovis and Flos Matricariae chamomillae are cleaned, chopping, the intense fire that adds water is fried open, and after boiling 1-5 minute, turns slow fire boiling 20-40 minute, and filter, filtrate leaves standstill 24-48 hour, gets supernatant stand-by;
(5) step (4) gained supernatant is placed in clean container; add lycopene, green tea extract, Caulis et Folium Lactucae sativae extract, vitamin E and astaxanthin; decoct while be stirred to crude drug and melt completely; step (1)-(3) gained smalls is added after melting completely; cease fire and add step (2)-(3) gained filtrate and glycerol; abundant stirring 2-6 minute, sterilizing 1-5 minute at 120-140 DEG C, bottles and get final product.
5. whitening according to claim 4 shone the preparation method of skin late frost, it is characterized in that: step (1) Thallus Laminariae (Thallus Eckloniae) eluriates 4-6 time, with the hot-water soak 11-13 of 93-98 DEG C hour (preferred, Thallus Laminariae (Thallus Eckloniae) eluriates 5 times, the hot-water soak 12 hours with 95 DEG C).
6. whitening according to claim 4 shines the preparation method of skin late frost, it is characterized in that: step (1) adds Thallus Laminariae (Thallus Eckloniae) weight 0.3-0.5 Pericarpium Citri Reticulatae doubly in the process of soaking, soak well and take out Thallus Laminariae (Thallus Eckloniae), be cut into filament, be placed in baking box to bake after 7-10 minute and (preferably, in the process of soaking, add the Pericarpium Citri Reticulatae of Thallus Laminariae (Thallus Eckloniae) weight 0.4 times, after immersion is good, take out Thallus Laminariae (Thallus Eckloniae), be cut into filament, be placed in baking box roasting after 8 minutes).
7. whitening according to claim 4 shines the preparation method of skin late frost, it is characterized in that: step (2) filtering residue is placed on iron plate, dries 3-5 minute to obtain smalls (preferred, filtering residue is placed on iron plate, and drying 4 minutes must smalls).
8. whitening according to claim 4 shines the preparation method of skin late frost, it is characterized in that: step (3) dry 4-6 minute smalls cross 90-110 mesh sieve stand-by (preferred, dries 5 minutes must smalls to cross 100 mesh sieves stand-by).
9. whitening according to claim 4 shines the preparation method of skin late frost, it is characterized in that: step (4) is after boiling 2-4 minute, turn slow fire boiling 25-35 minute, filter, filtrate leaves standstill 30-40 hour and (preferably, until boiling after 3 minutes, turns slow fire boiling 30 minutes, filter, filtrate leaves standstill 35 hours).
10. whitening according to claim 4 shines the preparation method of skin late frost, it is characterized in that: step (5) fully stirs 3-5 minute, at 125-135 DEG C sterilizing 2-4 minute (preferred, fully to stir 4 minutes, sterilizing 3 minutes at 130 DEG C).
CN201510292518.1A 2015-06-02 2015-06-02 Whitening peeling night cream capable of reducing melanin deposition and preparation method thereof Pending CN104825379A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510292518.1A CN104825379A (en) 2015-06-02 2015-06-02 Whitening peeling night cream capable of reducing melanin deposition and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510292518.1A CN104825379A (en) 2015-06-02 2015-06-02 Whitening peeling night cream capable of reducing melanin deposition and preparation method thereof

Publications (1)

Publication Number Publication Date
CN104825379A true CN104825379A (en) 2015-08-12

Family

ID=53803852

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510292518.1A Pending CN104825379A (en) 2015-06-02 2015-06-02 Whitening peeling night cream capable of reducing melanin deposition and preparation method thereof

Country Status (1)

Country Link
CN (1) CN104825379A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105147577A (en) * 2015-08-17 2015-12-16 彭小兰 Toner capable of relieving melanin deposition and preparation method of toner
CN105997732A (en) * 2016-07-11 2016-10-12 广州丹奇日用化工厂有限公司 Moisturizing toner containing lettuce extract

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005289880A (en) * 2004-03-31 2005-10-20 Naris Cosmetics Co Ltd Bleaching cosmetic
CN102871898A (en) * 2012-09-05 2013-01-16 福建泉州恒泉化妆品有限公司 Yellowness-improving and lightening and whitening lotion product and preparation method
CN103619319A (en) * 2011-06-28 2014-03-05 富士胶片株式会社 Astaxanthin-containing composition, method for manufacturing same, and cosmetic

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005289880A (en) * 2004-03-31 2005-10-20 Naris Cosmetics Co Ltd Bleaching cosmetic
CN103619319A (en) * 2011-06-28 2014-03-05 富士胶片株式会社 Astaxanthin-containing composition, method for manufacturing same, and cosmetic
CN102871898A (en) * 2012-09-05 2013-01-16 福建泉州恒泉化妆品有限公司 Yellowness-improving and lightening and whitening lotion product and preparation method

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
张建华: "《中医美容美体学》", 31 August 2012 *
藤家瑶: "《净.美肌:素肌美人完全攻略》", 30 April 2007 *
高俊全等: "《虾青素:健康新世纪的奥秘》", 31 July 2013 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105147577A (en) * 2015-08-17 2015-12-16 彭小兰 Toner capable of relieving melanin deposition and preparation method of toner
CN105997732A (en) * 2016-07-11 2016-10-12 广州丹奇日用化工厂有限公司 Moisturizing toner containing lettuce extract

Similar Documents

Publication Publication Date Title
CN103652361B (en) Feed for postpartum sow in lactation period of 1-20 days and preparation method thereof
CN102178844B (en) Oral Chinese medicine preparation for treating gum swelling and pain and preparation method thereof
CN102091258B (en) Chinese medicinal composition for dispelling scars and preparation method thereof
CN103520578B (en) A kind of Chinese medicine composition for the treatment of oral ulcer and preparation method thereof
CN103355555A (en) Feed for laying hen in egg-laying peak stage and preparation method thereof
CN104000127B (en) Semen phaseoli radiati refrigerant throat-moistening chewable tablet and production method thereof
CN109966417A (en) A kind of solid beverage for diabetic population
CN104381691A (en) Functional feed for preventing nutritional anemia of piglets and preparation method of functional feed
CN104856909A (en) Sleeping pack capable of reducing melanin sediments and preparation method thereof
CN107648454A (en) A kind of kidney tonifying cream taste and preparation method thereof
CN105125466A (en) Freckle removing night cream and preparing method thereof
CN105597071A (en) Traditional Chinese medicine composition for treating piglet iron-deficiency anemia and preparing method thereof
CN104739925A (en) Composition for treating acnes and preparation method for composition
CN103877247B (en) Medicine being used for the treatment of decubital ulcer and preparation method thereof
CN105147577A (en) Toner capable of relieving melanin deposition and preparation method of toner
CN103536826B (en) One is treated colpitic Chinese medicine composition and preparation method thereof
CN105213256A (en) A kind of Shu Min dispels red toner/smoothing toner and preparation method thereof
CN105125467A (en) Emulsion removing red blood and preparing method of emulsion
CN108497277A (en) Compound fruit and vegetable anticancer nutritional meal formula
CN104522213A (en) Tea suitable for three-high crowds and making method of tea suitable for three-high crowds
CN104825379A (en) Whitening peeling night cream capable of reducing melanin deposition and preparation method thereof
CN103859373A (en) Formula and preparation method of life cultivation and health preservation food helpful for preserving health during menstrual period
CN104856920A (en) Sleep facial mask capable of removing acne marks and preparation method of sleep facial mask
CN100506085C (en) Brown sugar health product capable of raising immunity of puerpera
CN103301357A (en) Formula and preparation method for traditional Chinese medicine preparation for promoting hair blacking

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
EXSB Decision made by sipo to initiate substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20150812

RJ01 Rejection of invention patent application after publication