CN104381691A - Functional feed for preventing nutritional anemia of piglets and preparation method of functional feed - Google Patents

Abstract

The invention discloses functional feed for preventing nutritional anemia of piglets and a preparation method of the functional feed. The functional feed comprises the following raw materials: corn flour, straw powder, soybean cake, fried soybean meal, bone meal, shell powder, salt, fish meal, carrot, taro, wheat bran, sorghum flour, rapeseed meal, trace element additive and lysine. The preparation method comprises the following steps of crushing the raw materials, mixing the raw materials, preparing feed particles and drying feed. The functional feed contains traditional-Chinese-medicine additives, is used for treating the nutritional anemia of the piglets, has the effects of tonifying qi and nourishing blood, strengthening spleen and helping the digestion, tonifying kidney, replenishing essence and producing marrow, also can enhance the resistance and has the advantageous characteristics of special technology, large effect, precise and appropriate drug selection, good quality and low price, safety, applicability, no drug residue and the like, and also can promote the growth of the piglets well.

Description

For preventing functional feed of the not optimum anaemia of piglet nutrition and preparation method thereof

Technical field

The present invention relates to field of animal feed, particularly relating to a kind of for preventing functional feed of the not optimum anaemia of piglet nutrition and preparation method thereof.

Background technology

Piglet nutrition anaemia (Nutritional Anemia of Piglet) refers to that in 5 ~ 28d, suckling pig is due to subalimentation and microelement deficiencies, the particularly shortage of iron and the anaemia caused, with visual mucous membrane look light clinically, slight xanthochromia or pale; In blood circulation erythrocyte number decline, hemoglobin significantly reduce wait be feature, be also called hypoferric anemia or microcytic hypochromic anemia.The multiple drylot feeding piglet, particularly pig house being born in season at the beginning of cold winter Mo, spring with plank or cement for ground and do not take the Intensive Farm of Pig Raising of benefit iron measure.This disease has mass-sending in a given area, and the incidence of disease, the death rate are higher, and all may occur every year, causes serious economic loss to pig industry.

The cause of disease: the physiological cause of disease: mainly iron deficiency or shortage, the first few weeks after piglet birth, grow rapidly, whole blood volume increases fast, need iron 7 ~ 15mg every day, and the iron of breast milk supply is only 1mg, so employ storage iron (being about 40 ~ 47mg) extremely meagre in body every day.And if this phase piglet growth can not contact with soil in the pig house being ground with cement or plank, lose and originate to the picked-up of iron, do not take again manually to mend iron measure simultaneously, and make piglet iron deficiency serious; Add achyli hydrochloric acid in the rear 7d of piglet birth, the iron of acquisition is just less, and the synthesis of result hemoglobin is not enough and occur physiologic anemia.The conditionity cause of disease: in piglet Dietary Supplement Dietary, the content of calcium carbonate and manganese too much can cause conditionity iron deficiency and anaemia, this is mainly because calcium carbonate and manganese all have antagonism to the absorption of iron.When protein, copper, cobalt, zinc, vitamin B12, folic acid, nicotinic acid, thiamine, riboflavin in daily ration etc. lack, can cause or promote the generation of piglet nutrition anaemia.Phosphoric acid, phytic acid, tannic acid, oxalic acid etc. all can be combined with iron, and hinder the absorption of iron, the too high levels of these materials in daily ration, also can promote the generation of this disease.Other: in addition, environmental factor is as many, dark and damp in pig house atmosphere draught-free, dust, dense stocking etc. all can increase the weight of anaemia.If piglet take in poisonous, containing alkaloidal feed and repeatedly or Long-Time Service certain medicine (chloramphenicol as national regulation food animal forbidding) also can accelerate the generation of anaemia.

Harm: in body, most iron is for the synthesis of hemoglobin, therefore iron deficiency will cause content of hemoglobin decline and RBC acceptor garland rate reduce and anaemia occurs.Anaemia lasts till that the regular period just can destroy the oxidation-reduction process of body, simultaneously piglet digest and assimilate hypodynamia, increased the weight of the generation of anaemia, and then brought out digestive system and respiratory illness etc. because immunity of organism reacts reduction, the death rate can reach 10% ~ 15%.

Clinical symptoms: sick pig spirit is depressed, peels off and lies prostrate, anorexia, inverse vertical by hair, lack gloss, poor growth or stopping.Body temperature is not high, accompanies diarrhoea more.Visual mucous membrane look light, slight xanthochromia or pale.Illumination auricular concha is canescence, almost can not see obvious blood vessel, and acupuncture is also seldom hemorrhage.Breathe and increase number, pulse rapidly, can hear anemicus intracardial accentuated; Light exercise then heartbeat is prosperous and powerful, gasps for breath.Can there is oedema in head and front body, sometimes phrenospasm occurs.Some piglet outward appearances are very fat, grow also very fast, can die by visitation of God in running.Some piglet outward appearances are become thin, and constipation diarrhea alternately occurs, different from, exhaustion; Stomach wall is crispaturaed, and its build is olive-shaped.

Pathological change: liver fat is out of shape and enlargement, in light gray, sometimes has blutpunkte.Blood is thin poor in water sample, coagulability; Meat color is thin out, and particularly gluteus and cardiac muscle present the change of typical anaemia.Spleen enlargement, tunicle thickens, and look shallow, and quality is slightly solid.Nephrolithotomy sex change, in canescence, tunicle is easily peeled off, tangent plane cortex and medullary substance boundary clear.Abdominal cavity, thoracic cavity, pericardial effusion, cardiac enlargement, the external membrane of heart has point hemorrhage.Pulmonary edema, interstitial is obvious, and tangent plane has diffusate to overflow.Lymphonodi mesenterici oedema, extravasated blood; Stomach and acoprosis, its mucous membrane has focal disease to become.

Histological examination: in marrow, RBC acceptor garland rate is strengthened, and has extramedullary hematopoiesis function at liver, spleen and lymph.

Prevention: the feeding and management strengthening latter half of gestation and milking sow, increases the supply of the exogenous chalybeate of suckling pig.Latter half of gestation and milking sow add health product balanced in nutrition " domestic animal orders No. 1 ", and suitably increase green succulent feed, ensure sufficient high-quality breast milk supply.Method is: iron-dextrin 2ml deep intramuscular injection, injects 1ml again after 7d; The deep intramuscular injection of ferrodextranum cobalt, each 2ml, significant anaemia person repeats 1 time every 2d Isodose.Existing methods for the treatment of, effect is not very desirable on the one hand, can cause retaining of toxicant on the other hand.

Malnutritional anemia belongs to Chinese veterinarian's consumptive disease category.Principle of reatment: for the treatment of consumptive disease take help as basic principle.Say as " Plain Questions three body parts and nine pulse taking sites opinion ": " treating deficiency with tonification." when carrying out help, one be must take beneficial gas respectively, nourish blood according to the difference of pathology attribute, enriching yin, Wen Yang treatment side's medicine; Two is will the Selection drug in conjunction with the difference of the five internal organs sick position closely, to strengthen the specific aim for the treatment of.When this basic principle of application help treatment consumptive disease, following 3 points should be noted: 1. pay attention to the effect of invigorating spleen and kidney in treatment consumptive disease.So that The spleen and stomach provide the material basis of the acquired, be source of generating QI and blood, the strong fortune of taste, the vital organs of the human body, four limbs bones of the body collectively can be nourished.The kidney being the origin of congenital constitution, and residence nephroyin and nephroyang is this yuan of life.Pay attention to invigorating spleen and kidney, first the foundation of acquired constitution is unbeaten, then can promote each dirty deficient recovery.2. for asthenia with sthenia and the outer evil person of sense of holding concurrently, rush down when bowl spares has, strengthening vital QI to eliminate pathogenic factors.From dialectical relation, the eliminating evil effect also can playing solid protection healthy tendency, prevents from damaging healthy tendency further because of heresy love.3. the course of disease of consumptive disease is longer, the many factors of impact, drug therapy be taken good care of oneself with diet care and life and closely combine, can receive better result for the treatment of.

Summary of the invention

Technical problem to be solved by this invention is, there is provided a kind of for preventing functional feed and the preparation method of the not optimum anaemia of piglet nutrition, the Chinese medicine additive that this functional feed contains, benefiting qi and nourishing blood, invigorating the spleen help the raw marrow of fortune, enriching kidney essence, the not optimum anaemia for the treatment of piglet nutrition have rapid-action, determined curative effect, security high, have no side effect.While cure rate is high, pollution-free, not easily recur after healing, cost price is cheap, can also ensure growing of piglet.

For solving the problems of the technologies described above, the invention provides a kind of for preventing the functional feed of the not optimum anaemia of piglet nutrition, wherein, described functional feed comprises following raw material: corn flour, powder of straw, soya-bean cake, stir-bake to yellowish bean powder, bone meal, Bei Fen, salt, fish meal, carrot, taro, wheat bran, Chinese sorghum face, the dish dregs of rice, trace mineral supplement and lysine.

Wherein, in described functional feed, the parts by weight of each raw material are: corn flour 25-40 weight portion, powder of straw 10-15 weight portion, soya-bean cake 5-10 weight portion, stir-bake to yellowish bean powder 12-26 weight portion, bone meal 10-25 weight portion, shellfish powder 10-20 weight portion, salt 1-3 weight portion, fish meal 5-10 weight portion, carrot 4-8 weight portion, taro 5-9 weight portion, wheat bran 15-20 weight portion, Chinese sorghum face 15-20 weight portion, dish dregs of rice 7-13 weight portion, trace mineral supplement 0.001-0.5 weight portion and lysine 0.01-0.2 weight portion.

Wherein, described functional feed also comprises Chinese medicine additive, in described feed, the parts by weight of each raw material are: corn flour 25-40 weight portion, powder of straw 10-15 weight portion, soya-bean cake 5-10 weight portion, stir-bake to yellowish bean powder 12-26 weight portion, bone meal 10-25 weight portion, shellfish powder 10-20 weight portion, salt 1-3 weight portion, fish meal 5-10 weight portion, carrot 4-8 weight portion, taro 5-9 weight portion, wheat bran 15-20 weight portion, Chinese sorghum face 15-20 weight portion, dish dregs of rice 7-13 weight portion, trace mineral supplement 0.001-0.5 weight portion, lysine 0.01-0.2 weight portion and Chinese medicine additive 6-12 weight portion.

Wherein, in described functional feed, the parts by weight of each raw material are: corn flour 40 weight portion, powder of straw 15 weight portion, soya-bean cake 10 weight portion, stir-bake to yellowish bean powder 26 weight portion, bone meal 25 weight portion, shellfish powder 20 weight portion, salt 3 weight portion, fish meal 10 weight portion, carrot 8 weight portion, taro 9 weight portion, wheat bran 20 weight portion, Chinese sorghum face 20 weight portion, the dish dregs of rice 13 weight portion, trace mineral supplement 0.01 weight portion, lysine 0.05 weight portion and Chinese medicine additive 7 weight portion.

Wherein, described Chinese medicine additive comprises following raw medicinal material: Radix Glycyrrhizae, fushen, polygala root, spina date seed, the banksia rose, arillus longan, date, the pig iron fall, magnetite, dark plum, the fruit of Chinese magnoliavine, silkworm chrysalis, laver, tortoise plastron, turtle shell, light wheat, cuttlebone, citron, walnut kernel, pine nut, the membrane of a chicken's gizzard, cultivated land, prepared fleece flower root, donkey-hide gelatin, fructus amomi, ventilago leiocarpa, Wilson Begonia Rhizome.

Wherein, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: Radix Glycyrrhizae 10-25 weight portion, fushen 10-20 weight portion, polygala root 10-15 weight portion, spina date seed 10-25 weight portion, banksia rose 5-8 weight portion, arillus longan 15-26 weight portion, date 20-30 weight portion, the pig iron falls 10-18 weight portion, magnetite 10-15 weight portion, dark plum 10-14 weight portion, fruit of Chinese magnoliavine 10-20 weight portion, silkworm chrysalis 13-26 weight portion, laver 20-30 weight portion, tortoise plastron 7-12 weight portion, turtle shell 6-12 weight portion, light wheat 10-20 weight portion, cuttlebone 12-23 weight portion, citron 10-20 weight portion, walnut kernel 20-30 weight portion, pine nut 18-24 weight portion, the membrane of a chicken's gizzard 10-19 weight portion, cultivated land 12-23 weight portion, fleece-flower root 13-20 weight portion, donkey-hide gelatin 25-35 weight portion, fructus amomi 10-16 weight portion, ventilago leiocarpa 12-24 weight portion, Wilson Begonia Rhizome 10-20 weight portion.

Wherein, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: Radix Glycyrrhizae 25 weight portion, fushen 20 weight portion, polygala root 15 weight portion, spina date seed 25 weight portion, the banksia rose 8 weight portion, arillus longan 26 weight portion, date 30 weight portion, the pig iron falls 18 weight portions, magnetite 15 weight portion, dark plum 14 weight portion, the fruit of Chinese magnoliavine 20 weight portion, silkworm chrysalis 26 weight portion, laver 30 weight portion, tortoise plastron 12 weight portion, turtle shell 12 weight portion, light wheat 20 weight portion, cuttlebone 23 weight portion, citron 20 weight portion, walnut kernel 30 weight portion, pine nut 24 weight portion, the membrane of a chicken's gizzard 19 weight portion, cultivated land 23 weight portion, the fleece-flower root 20 weight portion, donkey-hide gelatin 35 weight portion, fructus amomi 16 weight portion, ventilago leiocarpa 24 weight portion, Wilson Begonia Rhizome 20 weight portion.

Wherein, the preparation method of described Chinese medicine additive comprises the following steps:

The first step, mixes in proportion by described raw medicinal material, and adding relative to the determining alcohol of mixture quality 3 ~ 5 times is the ethanol of 80 ~ 90%, adds hot reflux 1 ~ 3 hour, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 1 ~ 2 times to be again the ethanol of 80 ~ 90%, to add hot reflux 1 ~ 3 hour that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;

Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;

3rd step, adds the starch relative to its quality 2 ~ 4 times in the micropowders obtained by second step, mixing, obtains powder.

For solving the problems of the technologies described above, present invention also offers a kind of preparation method of the described functional feed for preventing the not optimum anaemia of piglet nutrition, wherein, described preparation method comprises the following steps:

(1) broken raw material stage: take by ratio of weight and the number of copies soya-bean cake, carrot, taro, wheat bran, the dish dregs of rice drop into pulverizer carry out Crushing of Ultrafine, through pulverizing after cross 3.2mm sieve, obtain fine powder;

(2) mixed material step: take corn flour, powder of straw, stir-bake to yellowish bean powder, bone meal, Bei Fen, salt, fish meal, Chinese sorghum face, trace mineral supplement, lysine and Chinese medicine additive according to ratio of weight and number, pulverize with step (1) fine powder obtained to mix, drop into mixer, mix, incorporation time is 45-80s;

(3) feed granules step is manufactured: drop into granulator and granulate, pelleting temperature is 70 DEG C-80 DEG C, makes its gelatinization degree reach more than 94%.

(4) dry feed step: the feed granules obtained by (3) step, under temperature is 35-45 DEG C of environment, carries out air-dry airing, obtains functional feed.

The invention has the beneficial effects as follows: the Chinese medicine additive that this functional feed contains, benefiting qi and nourishing blood, invigorating the spleen help the raw marrow of fortune, enriching kidney essence, the not optimum anaemia for the treatment of piglet nutrition have rapid-action, determined curative effect, security high, have no side effect.While cure rate is high, pollution-free, not easily recur after healing, cost price is cheap, can also ensure growing of piglet.

Detailed description of the invention

For the corresponding symptom suffering from the not optimum anaemia appearance of piglet nutrition, the invention provides and a kind ofly comprise the Chinese medicine additive having and can nurse one's health pig spleen and stomach function, treatment short treating period, effect is better, residual quantity low while can develop immunitypty and resistivity, functional feed of green non-pollution and preparation method thereof.

Wherein Chinese medicine composition comprises: Radix Glycyrrhizae, fushen, polygala root, spina date seed, the banksia rose, arillus longan, date, the pig iron fall, magnetite, dark plum, the fruit of Chinese magnoliavine, silkworm chrysalis, laver, tortoise plastron, turtle shell, light wheat, cuttlebone, citron, walnut kernel, pine nut, the membrane of a chicken's gizzard, cultivated land, the fleece-flower root, donkey-hide gelatin, fructus amomi, ventilago leiocarpa, Wilson Begonia Rhizome.This compatibility of medicines in a prescription is reasonable, rigorous, helps the not optimum anaemia of the raw marrow treatment piglet nutrition of fortune, enriching kidney essence, can obtain desirable effect with benefiting qi and nourishing blood, invigorating the spleen.We are based on guipi decoction, and carry out diagnosis and treatment, addition or subtraction of changes, in its side, fushen, polygala root, spina date seed, the banksia rose, arillus longan, date, ventilago leiocarpa, Wilson Begonia Rhizome are medicine in guipi decoction, the party's tonifying heart and spleen, nourishing qi and blood; Arillus longan, date, the pig iron fall, magnetite supplements chalybeate; The fruit of Chinese magnoliavine, silkworm chrysalis, laver, tortoise plastron, turtle shell, light wheat, cuttlebone, walnut kernel, pine nut, cultivated land, the fleece-flower root, donkey-hide gelatin, the raw marrow of supplementing the kidney to control the nocturnal; Citron, the membrane of a chicken's gizzard, fructus amomi are regulated the flow of vital energy and are helped digestion, and prevent all medicines to hinder the property of stomach.Make a general survey of full side, compatibility is rigorous.For the not optimum anaemia for the treatment of piglet nutrition has good effect.

In described pharmaceutical composition, each component pharmacology is as follows:

Radix Glycyrrhizae: taste is sweet, property is put down, nontoxic.Can treating disorders in five ZANG-organs six internal organs fever and chills perverse trend, hard muscles and bones, longue meat, times strength, removing toxic substances, clothes are made light of one's life by commiting suicide and are prolonged life for a long time.Raw by purging intense heat heat, ripe use is fallen apart exterior cold, goes pharyngalgia, except heat symptoms caused by an exopathgen, and slow healthy tendency, yin-nourishing blood, tonifying spleen and stomach, moistening lung.Honey-fried licorice root, is longer than in temperature, and with sweet Wen Yiqi, relieving spasm to stop pain power is strong.Weak for insufficiency of the spleen stomach, palpitaition intermittent pulse etc.Modern study shows, Radix Glycyrrhizae has the effect of similar cortex hormone of aadrenaline sample.

Fushen: sweet, light; The thoughts of returning home, the spleen channel." property of medicine opinion ": " main frightened epilepsy, tranquilizing the mind, mends tired; Main acute pain in the epigastrium heavily fortified point is full, and small intestine is unfavorable." " medicineization justice ": " fushen, its body is heavy, and mental disorder may be cured with weighty sedatives, its benefit warm in nature, tonic prescription alleviating debility." the peaceful heart of function, calm the nerves, Li Shui.For palpitation with fear of having a guilty conscience, forgetful, insomnia, frightened epilepsy, difficult urination.

Polygala root: bitter, pungent, tepor; The thoughts of returning home, kidney, lung channel.Shennong's Herbal: " master coughs in inverse wound, and tonifying for the deficiency, except perverse trend, sharp nine orifices, intelligence development is intelligent, normal hearing and eyesight, does not forget, strong will times power." " Japan hanako materia medica ": " the frightened black mole of main diaphragm gas, longue meat, helps muscles and bones, and married woman's blood is kept silent aphonia, convulsive seizures induced by terror in children." intelligence development of calming the nerves, eliminate the phlegm, detumescence insomnia and dreamful sleep, forgetful palpitation with fear, wandering.Insomnia and dreamful sleep, palpitation and severe palpitation, forgetful.Epilepsy is shied mad, and spasm is twitched, skin sore.Modern pharmacological research shows, comparatively skin zone is low for polygala root xylem haemocylolysis.Full polygala root, polygala root skin, the polygala root heart all can strengthen syngignoscism when same dosage; Anticonvulsant action is the strongest with full polygala root, and polygala root skin takes second place, and the polygala root heart is invalid; With polygala root skin the most by force, full polygala root is taken second place, and the polygala root heart is the most weak for haemocylolysis and anxious poison experiment; Full polygala root with go heart polygala root to compare phlegm-dispelling functions not weaken.

Spina date seed: sweet, sour, property is put down.Thoughts of returning home warp, the spleen channel, Liver Channel, gallbladder channel.Shennong's Herbal: " bowl spares benefit liver, hard muscles and bones, helps cloudy gas, and all the merit of spina date seed also." " herbal classic ": " main trusted subordinate's fever and chills, evil knot gas gathers, painful limbs, arthritis with fixed pain caused by dampness." " not Lu ": " mainly vexatiously must not to sleep, navel is pain up and down, and blood turns to be let out for a long time, abnormal sweating polydipsia, bowl spares, beneficial irritability, and hard muscles and bones helps cloudy gas, makes us fertile strong." " property of medicine opinion ": " main muscles and bones wind is fried end and is taken it as soup.Function " nourishing the liver, Ning Xin, calms the nerves, arrest sweating.There are calmness, hypnosis, analgesia, anticonvulsant action; There is certain hypotensive effect; Excitation is had to uterus.For deficiency of YIN-blood, palpitation and severe palpitation, insomnia forgetfulness; The empty hidrosis of body.

The banksia rose: arduous, cold.Enter lung, stomach warp.Promoting the circulation of qi, removing toxic substances, detumescence.Tang Materia Medica: " master gathers.All scorchingly hot swollen, snake venom, water rub into mudding it, day three, four; Treat malignant boil enlargement effect." " vegetation is side just ": " delivers, except wind.(controlling) rheumatism is paralysed, waist pin pain, traumatic injury." promoting the circulation of qi, removing toxic substances, detumescence.Control chest and abdomen swelling and pain, acute filthy disease, enteritis diarrhea, hypertension, hernia, snake stings poison, and carbuncle swells, furunculosis, pruitus or wet rotten.

Arillus longan: nourishing blood and tranquilization.Sallow for insufficiency of vital energy and blood, palpitation and severe palpitation, forgetful insomnia, the deficiency of blood." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " whet the appetite beneficial spleen for nourishing blood and tranquilization, long intelligence arrest sweating." " Quanzhou book on Chinese herbal medicine ": " establishing-Yang benefit gas, tonifying spleen and stomach.Control married woman's postpartum edema, deficiency of vital energy oedema, splenasthenic diarrhea.Tonifying heart and spleen, " nourishing blood and tranquilization.Sallow for insufficiency of vital energy and blood, palpitation and severe palpitation, forgetful insomnia, the deficiency of blood.Contained by longan, sugar amount is very high, is the monose of absorption easy to digest, can be directly absorbed by the body, thus weak anaemia, worn with age, weakness due to chronic disease, often eating a little longan is have benefiting action very much; Women postpartum, longan is also that food mended in important tune.Because iron content and vitamin B2 are very abundant, uterine contractile and the sagging sense of palace body can be alleviated.

Date: taste is sweet, warm in nature, enter spleen, stomach warp.There is the effect of air making-up and spleen enlivening, nourishing blood and tranquilization, harmonizing yingfen and weifen, the mitigation property of medicine, for weakness of the spleen and the stomach, fatigue and asthenia, anorexia and loose stool, insufficiency of vital energy and blood, has a headache and fever, the cards such as sweating hot blast, date has the effect strengthening muscular strength, has and increases total serum protein and albuminous function.CAMP contained by red date is the required composition of human body cell energetic supersession, can strengthening muscular strength, dispelling fatigue, hemangiectasis, increase myocardial contractive power, improve myocardial nutrition, having good effect to preventing and treating disease of cardiovascular system; Red date has good therapeutic effect to illnesss such as chronic hepatitis, cirrhosis, anaemia, anaphylactoid purpuras; Red date contains triterpene compound and CAMP, has stronger anticancer, anti-allergic effects.Date can moisten cardiopulmonary, cough-relieving, tonifying five zang organs, it is deficient to control, except stomach addiction gas, support spleen, flat stomach Qi, logical nine orifices in can also pacifying, help 12 through etc.

The pig iron falls: for the pig iron is calcined to red red, hammered into shape the iron filings fallen during outer oxide.Get the iron of laying when forging iron to fall, remove its coal soil impurity, clean, dry.Or forge rear vinegar and to quench use.The property of medicine is pungent, cool.Return liver, the heart channel of Hang-Shaoyin.Effect is checking hyperfunction of the liver and relieving convulsion.Apply 1. demented.The pungent cool matter weight of this product, is good at flat liver, and the flat then fire of wood falls, therefore says lower gas quickly, and gas and fire are also.2. easily shy kind anger, insomnia.3. sore swollen toxin.4. joint pain, sprains pain.1. Shennong's Herbal: " main air heat, dislike sore, ulcer, subcutaneous ulcer sore, scab scabies, gas in skin." 2. " Japan hanako materia medica ": " control frightened evil epilepsy, convulsive seizures induced by terror in children, help digestion and cold air, and decoct juice and take it." 3. Compendium of Material Medica: " flat liver goes timid, controls kind anger and goes mad." modern study 1. chemical composition: the pig iron falls main containing tri-iron tetroxide, or name magnetic oxide (Fe3O4 or FeOFe2O3).2. pharmacological action: iron falls and forges after vinegar quenches through fire, becomes ferric acetate, makes to be easy to absorb, and can promote the new life of red coin born of the same parents and the numerical value of increase ferroheme, have blood tonification effect.And have certain sedation.

Calcined MAGNETITUM: Xin Xian is flat, nontoxic; Enter kidney channel, Liver Channel, lung channel." Japan hanako materia medica ": " control eye dusk, muscles and bones is thin and weak, mends general debility, except irritated, and detumescence poison." " Mingyi Bielu ": " support kidney to hide, strong moral integrity, beneficial smart relieving restlessness, gets round by bribery, subduing inflammation mouse fistula, and neck core is had sore throat, pediatric epilepsy scared." function is calming the liver, calm the nerves relieving convulsion, hearing-improing and eyesight improving, promoting inspiration to relieve asthma.Main dizzy order flower, deafness, tinnitus, palpitation with fear, insomnia, suffering from a deficiency of the kidney, it is inverse to breathe heavily.After rat intravenous injection, hemoglobin level in animal blood, red blood cell and leukocyte count can be made to increase, blood coagulation time extends and plasma fibrin degrading activity increases, and neutrophil phagocytosis reaction simultaneously increases.Magnetite concocts rear calmness and anticonvulsant action obviously strengthens.

Dark plum: bitter, acid, puckery, warm in nature, enters liver, lung, spleen, large intestine channel, promotes the production of body fluid to quench thirst, controlling nocturnal emission with astringent drugs contracting band contracting urine, relieving pain by calming ascaris.Supplement to the Herbal: " remove phlegm, main malaria miasma, quench the thirst in adjusting, except cold and hot dysentery, antiemetic is inverse." " Japan hanako materia medica ": " except labor, control hectic fever due to yin, go unhappiness, antidysentery with astringent, disappear wine poison, and control hemiplegia skin paralysis, de-black point, makes us sleeping.Enter to build again tea, rhizoma zingiberis is ball, only recurrent dysentery." have and astringe the lung, puckery intestines, hemostasis, the effect of promoting the production of body fluid, be used for the treatment of protracted dysentery more than, damp-heat dysentery, have blood in stool, hematuria, the card such as snowslide.Dark plum has the function of sterilization, also prevents food from degenerating in stomach.Malic acid in dark plum directs into large intestine appropriate moisture, forms ight soil and excretes.When blood purification, metabolism just strengthens, and health can recover energy naturally.Citric acid in dark plum helps to absorb vitamin and ferment, and also having can prevent disease and dispelling fatigue.

The fruit of Chinese magnoliavine: warm in nature, taste is sour, sweet, returns lung, the heart, kidney channel, restrains astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, effect of kidney calming, breathe heavily for void of coughing for a long time, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and feeble pulse of losing heart, interior heat is quenched one's thirst, the cards such as palpitation and insomnia.Tang etc. " Tang materia medica " carry " the sweet acid of five tastes skin and flesh, arduous in core, have saline taste ", therefore have the name of the fruit of Chinese magnoliavine.Ancient medical book Cheng Ta Chi Zhu, profound and, meeting and, it is top grade to list in Sheng Nong's herbal classic the earliest, and herbal function is the power of strengthening by means of tonics, and medical value is high, and general collocation selenium making nourishing the liver sheet and DDB, Bicyclol etc., have liver protecting function.The fruit of Chinese magnoliavine is divided into 2 genus, i.e. Kadsura and Schizandra.These seeds are easily planted, slightly life, and survival rate is high.Have convergence astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, effect of kidney calming, breathes heavily for void of coughing for a long time, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, and Tianjin wound is thirsty, and feeble pulse of losing heart, interior heat is quenched one's thirst, the cards such as palpitation and insomnia.The fruit of Chinese magnoliavine has antiinflammation, to prevent hepar damnification, activates anabolic process to promote the reparation of wounded hepatocytes, and can strengthen the activity of DNA (DNA) synthetic and ornithine decarboxylase, regeneration liver cell.

Silkworm chrysalis: sweet, flat.Composition: pupa is containing protein, fat oil, and wherein main component is unrighted acid, glycerine vinegar, a small amount of lecithin, black alcohol, liposoluble vitamin etc.Silkworm excrement (silkworm dung), containing organic matter, wherein has protein and chlorophyll, and containing auxin and histidine.Silkworm excrement after solar radiation, has effect of calcification skeleton after little chicken feed, or be that its contained vitamin D prime material belongs to 2,1-dihydro calcium alcohol is therefore.Efficacy effect aspect, silkworm chrysalis be weak, after being ill, old man and the high-grade nutrient tonic in puerpera postpartum.Silkworm chrysalis can produce has pharmacological active substance, can effectively improve leucocyte level in human body, thus improve immunity, delay senility.Silkworm chrysalis oil can reducing blood lipid, norcholesterol, to treatment hypercholesterolemia with improve liver function and have remarkable effect.Silkworm chrysalis is stir-fried and eaten and is controlled the thin and infantile emaciation of labor, and silkworm chrysalis oil has certain effect to hypertension, fatty liver, hyperlipidemia etc.The larva of a silkworm with batrytis controls the pediatric epilepsy scared morbid night crying of babies, convulsion wind summarized mouth.Evening, silkworm excrement infusing drugs in wine delayed all wind, went stupid numbness.Silk cocoon is controlled and is quenched one's thirst, and stops blooding and controls bleeding from the gum.

Laver: taste is sweet, salty, cool in nature.Laver energy radioresistance, anti-sudden change, anti-oxidant, relevant containing selenium with it.Polysaccharide contained by laver has obviously enhancing cellular immunity and humoral immune function, can promote lymphocyte transformation, improves the immunity of body; Significantly can reduce the total content into serum cholesterol, be rich in choline and calcium, iron, memory can be strengthened, treatment woman anemia, the growth promoting bone, tooth and health care; Containing a certain amount of sweet mellow wine, can be used as the accesary foods for the treatment of oedema, be especially applicable to Thyroid Gland Swell, oedema, chronic bronchitis, cough, goiter and tumor, gonorrhoea, beriberi, hypertension, the tuberculosis initial stage, cardiovascular disease and all kinds of lump, hyperplasia patient more suitable edible.

Tortoise plastron: salty, sweet, is slightly cold; Return liver, kidney, the heart channel of Hang-Shaoyin.Nourishing and suppressing Yang, the strong bone of kidney-nourishing, bushing of nourishing blood.Compendium of Material Medica: " bushing, kidney tonifying, to enrich blood, all with yin-nourishing also ... see tortoise plastron and lead all diseases, all genus deficiency of Yin blood is weak." nourishing and suppressing Yang, the strong bone of kidney-nourishing, bushing of nourishing blood.For deficiency of Yin hectic fever, hectic fever due to yin night sweat, has a dizzy spell, endogenous deficient wind, and muscles and bones impotence is soft, has a guilty conscience forgetful.Certain contraction is had to Isolated Rat Uterus during decoction high concentration; Inhibitory action is had to Bacillus tuberculosis; The continuous gavage of tortoise plastron decoction has impact to rat internal system in 6 days.Tortoise plastron can improve animal " deficiency of Yin " and demonstrate,prove pathology animal functional state, makes it to recover normal; Immunologic function can be strengthened; There is the effect of bidirectional modulation DNA synthetic ratio; All excitation is had in vitro and Uterus in vivo; Have antipyretic, enrich blood, sedation; Still there is anticoagulation, increase coronary flow and improve the effects such as hypoxia-bearing capability; Colla carapacis et plastri testudinis has certain effect promoting leukocyte count.

Turtle shell: salty, cold, returns liver, kidney channel.Nourshing kidney checking exuberance of yang, softening and resolving hard mass." property of medicine opinion ": " main place food, disease block, Xuan addiction gas, cold lump in the abdomen, labor are thin, lower gas, and except bone heat, between joint, labor heat, is solidly jammed.Control married woman leak down the five colors win thin person." cure mainly hectic fever due to yin labor heat, malaria is female, lower hard, the pain in the back of the side of body, through closing the diseases such as abdominal mass.It is inhibited that the oral 280mg/kg of Turtle Shell transplants solid carcinoma MH134 to mouse, and diameter of tumor is reduced, and tumor weight significantly alleviates.With 0.5% or 1.0% soft-shelled turtle polysaccharide Renger immersion bubble Toad Sciatic Nerve specimen-gastrocnemius muscle, there is the effect increasing and shrink highly and draw line area, extend the contracts last time.These product can suppress the hyperplasia of connective tissue, and can disappear caking; And there is the effect increasing plasma protein, there is the anaemia called and can be used for caused by hepatopathy.

Light wheat: Gan Xian, cool, thoughts of returning home warp.Compendium of Material Medica: " beneficial gas heat extraction, only spontaneous sweating, hectic fever due to yin labor heat, married woman Lao Re." " herbal classic is met former ": " swimmer, can hold back night sweat, gets the heat of its loose myocutaneous junction, site where the skin and muscle are joined also." except abnormal heat, hidroschesis.Main only fever due to yin deficiency, night sweat, spontaneous perspiration.Be rich in starch, protein, fat, mineral matter, calcium, iron, thiamine, riboflavin, nicotinic acid, vitamin A and vitamin C etc.

Cuttlebone: taste is salty, puckery, slightly warm in nature.Return liver, kidney channel.Warm in nature, sweet and slightly bitter taste, returns liver the spleen channel.Supplementary Amplifications of the Compendium of Materia Medica: " and blood, promoting circulation of blood, regulates the flow of vital energy.Control wandering arthritis." " book on Chinese herbal medicine is new again ": " the strongly fragrant gas of liver and gall of relaxing, fire falls in invigorating the spleen.Control crymodynia in abdomen, gastral cavilty is long-pending cold, holds concurrently and can break blood." sharp gas, promoting circulation of blood, control wandering arthritis, loose tired pain relieving.Compendium of Material Medica: " main woman's blood depletion is sick, the impariment of the liver, blood under spitting blood, and preventing and curing malaria disappears goitre.Cuttlebone grinds deposited children's's infantile malnutrition due to digestive disturbances or intestinalparasites sore into powder, and variola is smelly rotten, husband's erosion of vulva, and burn is got injured by a fall hemorrhage." effect astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, relieving haperacidity sore.Calcium carbonate contained in cuttle bone, can do only sour agent.Raw cuttlebone is longer than treating spontaneous emission and leukorrhagia, relieving haperacidity.Be usually used in emission, leukorrhea with reddish discharge, stomachache acid regurgitation.After frying, flavoring is smelly, and the property of inducing astrigency strengthens, and is longer than astringing to arrest bleeding, only band, sore.Can be used for metrostaxis, traumatic bleeding, leukorrhea with reddish discharge, sore eczema.

Citron: taste is pungent, sweet, nontoxic.Dispersing stagnated hepatoqi, wide chest reduces phlegm, dehumidifying and in.Cure mainly lower gas, except mind phlegm water.Boil wine to drink, control mental disorder cough." explaining abstruseness of the canon of materia medica ": " gas of the reason part of the body cavity above the diaphragm housing the heart and lungs, preventing or arresting vomiting is inverse, feed, invigorating the spleen." " book on Chinese herbal medicine is new again ": " flat liver Shu Yu, reason lung qi, stimulate the menstrual flow Li Shui, controls waist beriberi." function dispersing stagnated hepatoqi, wide chest reduces phlegm, dehumidifying and in.Cure mainly lower gas, except mind phlegm water.Boil wine to drink, control mental disorder cough.Decoct water, under controlling the heart, gas bitterly.Root leaf is skin-deep same.These product are pungent can manage it loose, and the catharsis of bitter energy, enters Liver Channel and can unclog and readjust irritability and pain relieving.Control liver depression distending pain in the chest and hypochondrium, gas perfume (or spice) is amusing, and pungent row hardship is let out, enter taste wide with promoting the circulation of qi in.With the abdominal distention controlling the taste stagnation of the circulation of vital energy, bitter dry the falling of these product is let out with preventing phlegm from forming and stopping coughing, and pungent row enters lung and wide chest of regulating the flow of vital energy.With controlling that phlegm is many, cough, uncomfortable in chest etc.Hesperidine contained by these product to cavy for want of vitamin C and cause eyes bulbar conjunctiva intravascular cells cohesion and capillary resistance reduce be improved effect, the cohesion of horse haemocyte can be reduced.Hesperidine has prevention frostbite and suppresses the aldehyde reductase effect of rat lens.Obakunone has the effect strengthening isolated rabbit intestines tension force and amplitude.

Walnut kernel: taste is sweet, warm in nature, enter kidney, lung, large intestine channel, there is tonifying kidney and benefiting sperm, warm lung Dingchuan, the effect relaxed bowel, pain in the back leg for kidney qi virtual loss is soft, dizzy weak, frequent micturition is passed out semen, and quenches one's thirst, coughing of deficiency of both the lung and kidney is breathed heavily, few and the dry constipation of intestines that are that cause of the elderly's deficiency of vital energy and anemia in postpartum Tianjin, traumatic injury, sore carbuncle is swollen waits card.Phosphatide in walnut, has fine health-care effect to cranial nerve.Walnut oil contains unrighted acid, has the arteriosclerotic effect of control.Containing indispensable trace elements of human body such as zinc, manganese, chromium in walnut kernel.Human body zinc, Fe content in aging course day by day reduce, and chromium has promotion glucose utilization, cholesterol metabolic and the cardiovascular function of protection.The antitussive and antiasthmatic effect of walnut kernel is also fairly obvious, winter, to chronic bronchitis and asthmatics's excellent curative.

Pine nut: sweet, temperature.Moistening lung, laxation.For xeropulmonary cough, chronic constipation.Pine nut has effect that is nourshing Yin and drynsessmoistening prescription, righting qi-restoratives, is particularly suitable for the patients such as body void, constipation, cough and eats.What is particularly worth mentioning is that, the defecating feces excretion of pine nut is gentle, is thus particularly suitable for getting old and weak, after being ill, the constipation person in postpartum eats.As desirable SEMEN PINI KORAIENSIS 20 grams pulverizes, cook congee with polished rice 100 grams, a point morning and evening takes.Pine nut is the high-quality nutritious supplementary pharmaceutical of brain, is particularly suitable for overstrain one's nerves crowd and eats.Unrighted acid contained in pine nut has the metabolism of enhancing brain cell, safeguards the effect of function of brain cell and nervous function.Content of glutamic acid is up to 16.3%, and glutamic acid has good brain strengthening function, can strengthen memory.

The membrane of a chicken's gizzard: taste is sweet, cold in nature, enter spleen, stomach, small intestine, urinary bladder channel, " Japan hanako materia medica ": " stopping leak essence, and under hematuria, metrorrhagia, band, intestines wind, rush down dysentery." " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " wide middle invigorating the spleen, help digestion mill stomach.Control children's's breast food knot stagnant, the large muscle of tripe is blue or green, mass in the abdomen infantile malnutrition due to digestive disturbances or intestinalparasites." have reinforcing spleen to promote digestion, puckery essence to stop the effect of drowning, be mainly used in the abdominal fullness and distention of dyspepsia stagnation, heating installation is suffered from diarrhoea, the symptoms such as infant malnutrition, and the membrane of a chicken's gizzard can promote gastric secretion, strengthens peristole, accelerate the effects such as gastric emptying.

Cultivated land: taste is sweet, slightly warm in nature, enters liver, kidney channel, kidney tonifying, essence replenishing, nourishes blood and the moon, the raw marrow of yin-nourishing, and tonifying five zang organs internal injury is not enough, promoting blood circulation, sharp knowledge, black beard and hair, man's general debility, and threatened abortion in woman's wound, irregular menorrhea, tire produces all kinds of diseases and ailments.Compendium of Material Medica: " fill out marrow, longue meat, promoting vital essence and blood genernation.Tonifying five zang organs internal injury is not enough, promoting blood circulation, sharp knowledge, black beard and hair, man's general debility, and threatened abortion in woman's wound, irregular menorrhea, tire produces all kinds of diseases and ailments." there is enriching yin of enriching blood, beneficial essence fills out the effect of marrow, sallow for the deficiency of blood; Dizzy, palpitaition, insomnia, irregular menstruation, collapses more than; Liver-kidney Yin deficiency, night sweat, sufficient knee pain, soreness and weakness of waist and knees, Hiccough and deaf, the head is dim-sighted, and seminal emission impotence, infertility, irregular menstruation, metrostaxis, poliosis, quenches one's thirst, the cards such as syndrome characterized by dyspnea of suffering from a deficiency of the kidney.

The fleece-flower root: bitter, sweet, puckery, tepor; Return liver, kidney channel.Cure mainly liver kidney asthenia of essence and blood, soreness and weakness of waist and knees, seminal emission tinnitus, has a dizzy spell." book on Chinese herbal medicine converges and says ": " have micro-poison.Enter to lead in liver, close in wind outward, rise also, sun also." " Kaibao Bencao ": " originally go out along Nanhe River county, state, outside modern ridge, south of the River Zhu Zhou all has.Climing purple, in vain brightly yellowish, leaf as Chinese yam not only.Life must be relative, and root is large has red, white two kinds as fist, and red person is male, and white person is female ... spring, Xia Cai." can detoxify, disappear carbuncle, relaxes bowel.Cure mainly liver kidney asthenia of essence and blood, soreness and weakness of waist and knees, seminal emission tinnitus, has a dizzy spell, palpitation and insomnia, poliosis, the dry constipation of spleen, rubella tinea scabies, pruitus, malaria, scrofula, temperament wind, hemorrhoid, sore carbuncle.Have promotion hematopoiesis function, strengthen immunologic function, reducing blood lipid and antiatherosclerosis, protect the liver, and the fleece-flower root contains the active ingredients such as Chrysophanol, archen, Rhein, Physcion, fat oil, starch, carbohydrate, rhaponticin, lecithin.Pharmacological research proves, the fleece-flower root can promote the conversion of human lymphoblastoid cell.Still there is effects such as reducing serum cholesterol, anti arteriosclerosis, anti-light poison.

Donkey-hide gelatin: taste is sweet flat, enters lung, liver, kidney channel, has effects such as tonifying the blood and arrest bleeding, nourshing Yin and drynsessmoistening prescription, sallow for the deficiency of blood, dizzy palpitaition, dysphoria and insomnia, xeropulmonary cough.All control to breathe heavily cough, no matter the deficiency syndrome of the lung, lung are real, can under can temperature, palpus donkey-hide gelatin is to pacify lung moistening lung, and its property is peaceful, is lung channel key medicine.The not positive person of pupil of the eye after child convulsion, the best with donkey-hide gelatin times ginseng decoction, god educated by donkey-hide gelatin, and ginseng benefit gas also.Dysentery is many again forms because of affection by summer heat latent heat, and donkey-hide gelatin is the key medicine of large intestine, has the hot poison person of being detained, then can dredge, without the hot poison person of being detained, then and can safety.Scold and be enough to accumulateing of invention donkey-hide gelatin.

Fructus amomi: taste is pungent, warm in nature; Return the spleen channel, stomach warp, kidney channel.Dampness elimination is whetted the appetite, warming spleen and stopping diarrha, regulates the flow of vital energy antiabortive.Materia Medica of Decoction: " contracting sand, with Asiatic sweet leaf, cardamom for making, enters lung, with ginseng, intelligence development for making, enters spleen, with golden cypress, Poria cocos for making, enters kidney, with red, kaolinite for making, enters large and small intestines." " Japan hanako materia medica ": " control all gas, choleraic myospasm, pain in the chest and abdomen." function dampness elimination appetizing, warming spleen and stopping diarrha, regulate the flow of vital energy antiabortive.For turbi damp obstructing in middle-JIAO, gastral cavity ruffian is not hungry, deficiency-cold in spleen and stomach, and vomiting is had loose bowels, pernicious vomiting, fetal irritability.The pungent loose temperature of these product is led to, fragrant, and its dampness elimination is amusing, and the effect in promoting the circulation of qi temperature is all good, and ancients say it: " adjust stomach key medicine for being amusing." therefore incoordination between the spleen and the stomach all cards such as all dampness or the abdominal distention caused by the stagnation of the circulation of vital energy are conventional, especially cold-dampness stagnation of the circulation of vital energy person is the most suitable.These product kind energy Wen Zhongnuan stomach is to reach the merit of preventing or arresting vomiting antidiarrheal, but it focuses on warm spleen.

Ventilago leiocarpa: another name blood wind root, smoothfruit ventilago root and stem, red serpentaria, blue veins rattan, car pusher enter stone, draw ox to enter stone.Source Rhamnaceae Ventilago plant ventilago leiocarpa Ventilago leiocarpa Benth., is used as medicine with root.The whole year can adopt, and cleans section, dries.Nature and flavor are bitter, temperature.Function cures mainly nourishing the blood to expel wind, stimulates the circulation of the blood and cause the muscles and joints to relax.For rheumatalgia, traumatic injury, lumbar muscle strain, anaemia is dizzy, numb limb, irregular menstruation.

Wilson Begonia Rhizome: be born on small stream limit or dark and damp stone rock.Distribution is had in Sichuan.Chemical analysis root-like stock shows cardiac glycoside, flavonoids, tannin, phenols, sterol, triterpenes, saponin reaction.Nature and flavor are sweet, bitter, flat.Function cures mainly air making-up and spleen enlivening, nourishes blood, stops blooding.Weak after being ill, cough spitting of blood, functional uterine bleeding, leukorrhea.

Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.

Embodiment 1 Chinese medicine additive

25 parts, Radix Glycyrrhizae, fushen 20 parts, polygala root 15 parts, spina date seed 25 parts, the banksia rose 8 parts, arillus longan 26 parts, 30 parts, date, the pig iron fall 18 parts, magnetite 15 parts, dark plum 14 parts, 20 parts, the fruit of Chinese magnoliavine, silkworm chrysalis 26 parts, laver 30 parts, tortoise plastron 12 parts, turtle shell 12 parts, light wheat 20 parts, cuttlebone 23 parts, citron 20 parts, walnut kernel 30 parts, 24 parts, pine nut, the membrane of a chicken's gizzard 19 parts, 23 parts, cultivated land, the fleece-flower root 20 parts, 35 parts, donkey-hide gelatin, fructus amomi 16 parts, ventilago leiocarpa 24 parts, Wilson Begonia Rhizome 20 parts.

Its preparation process is:

The first step, mixes in proportion by described raw medicinal material, and adding relative to the determining alcohol of mixture quality 3 times is the ethanol of 80%, adds hot reflux 1 hour, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 1 times to be again the ethanol of 90%, to add hot reflux 3 hours that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;

Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 2 hours, pulverize, sieve, obtain 350 object micropowders;

3rd step, adds the starch relative to its quality 2 times in the micropowders obtained by second step, mixing, obtains powder.

Embodiment 2 functional feed

Corn flour 40 weight portion, powder of straw 15 weight portion, soya-bean cake 10 weight portion, stir-bake to yellowish bean powder 26 weight portion, bone meal 25 weight portion, shellfish powder 20 weight portion, salt 3 weight portion, fish meal 10 weight portion, carrot 8 weight portion, taro 9 weight portion, wheat bran 20 weight portion, Chinese sorghum face 20 weight portion, the dish dregs of rice 13 weight portion, trace mineral supplement 0.01 weight portion, lysine 0.05 weight portion and Chinese medicine additive 7 weight portion; The Chinese medicine additive selected is Chinese medicine additive prepared by embodiment 1.Mineral additive comprises ferrous fumarate, zinc methionine, sodium selenite.Trace mineral supplement comprises iron, copper, manganese.

Its preparation process is:

(1) broken raw material stage: take by ratio of weight and the number of copies soya-bean cake, carrot, taro, wheat bran, the dish dregs of rice drop into pulverizer carry out Crushing of Ultrafine, through pulverizing after cross 3.2mm sieve, obtain fine powder;

(2) mixed material step: take corn flour, powder of straw, stir-bake to yellowish bean powder, bone meal, Bei Fen, salt, fish meal, Chinese sorghum face, trace mineral supplement, lysine and Chinese medicine additive according to ratio of weight and number, pulverize with step (1) fine powder obtained to mix, drop into mixer, mix, incorporation time is 45-80s;

(3) feed granules step is manufactured: drop into granulator and granulate, pelleting temperature is 70 DEG C, makes its gelatinization degree reach more than 94%.

(4) dry feed step: the feed granules obtained by (3) step, under temperature is 45 DEG C of environment, carries out air-dry airing, obtains functional feed.

The toxicity test of pharmaceutical composition

1. trial drug: by 10 parts, raw medicinal material Radix Glycyrrhizae, fushen 10 parts, polygala root 10 parts, spina date seed 10 parts, the banksia rose 5 parts, arillus longan 15 parts, 20 parts, date, the pig iron falls 10 parts, magnetite 10 parts, dark plum 10 parts, 10 parts, the fruit of Chinese magnoliavine, silkworm chrysalis 13 parts, laver 20 parts, tortoise plastron 7 parts, turtle shell 6 parts, light wheat 10 parts, cuttlebone 12 parts, citron 10 parts, walnut kernel 20 parts, 18 parts, pine nut, the membrane of a chicken's gizzard 10 parts, 12 parts, cultivated land, the fleece-flower root 13 parts, 25 parts, donkey-hide gelatin, fructus amomi 10 parts, ventilago leiocarpa 12 parts, purple casserole is put in Wilson Begonia Rhizome 10 parts of mixing, add clear water, to clear water dipped medicinal material upper surface 5cm, soak 7 hours, be placed in by purple casserole on fire, after intense fire boils, using slow fire instead, to decoct the 30 minutes dosage to liquid be slowly 300ml, filters, obtain filtrate a, for subsequent use, the residue dregs of a decoction are added clear water again, to clear water dipped medicinal material upper surface 3cm, soaks 10 hours, be placed in by purple casserole on fire, after intense fire boils, using slow fire instead, to decoct the 25 minutes dosage to liquid be slowly 300ml, filters, obtain filtrate b, filtrate a and filtrate b is mixed to get decoction.

2. test method:

Method one: acute toxicity test: selecting the white mouse that 20 vital signs are identical, take trial drug as object, gives dispensing in white mouse large intestine, observes 7 for 150 times of clinical consumption per day.The all white mouse of result are strong deposits, and its activity, diet, hair, excreta are no abnormal, have no toxic reaction.Irritation test is carried out to white mouse vagina and damaged skin, there are no irritative response and other bad reaction.Toxicity test proves, this trial drug one does not have toxic action and bad reaction, and clinical practice is safe and reliable.

Method two: cumulative toxicity test: select 20 healthy mices, female, each 10 of hero, take trial drug as object, dose design is first phase in every 5 days, each issue dosage is respectively 0.10LD50,0.15LD50,0.22LD50,0.34LD 50,0.50LD50, the LD 50 that is female, male mice of this sample be 5000m part/k part BW (five dosage is 500,750,1100,1700,2500m part/k part BW).Within every 5 days, weigh once, adjustment dosage, by 0.1ml/10 part BW per os gavage.After 20 days, small white mouse occurs without death condition, off-test, and by ascending-dose to tested material after 20 days, female, buck all occurs without death condition.Prove, this trial drug two does not have cumulative toxicity, and clinical practice is safe and reliable.

Contrast test

Contrast test

Pig farm, Shandong cultivation pig about 2000, gives birth to piglet 1400, in April, 2013, about has 500 piglets to occur the symptom of malnutritional anemia: sick pig spirit is depressed, peels off and lies prostrate, anorexia, inverse vertical by hair, lacks gloss, poor growth or stopping.Body temperature is not high, accompanies diarrhoea more.Visual mucous membrane look light, slight xanthochromia or pale.Illumination auricular concha is canescence, almost can not see obvious blood vessel, and acupuncture is also seldom hemorrhage.Breathe and increase number, pulse rapidly, can hear anemicus intracardial accentuated; Light exercise then heartbeat is prosperous and powerful, gasps for breath.Can there is oedema in head and front body, sometimes phrenospasm occurs.Some piglet outward appearances are very fat, grow also very fast, can die by visitation of God in running.Some piglet outward appearances are become thin, and constipation diarrhea alternately occurs, different from, exhaustion; Stomach wall is crispaturaed, and its build is olive-shaped.

Select 100 ill piglets, isolation cultivation, and be divided into two groups at random, functional feed group and control group, often organize 50.

Functional feed group adopts the functional feed of the embodiment of the present invention 2 to feed, and normally feeds, carries out 10.

Control group: with ferrous sulfate 2.5g, cobalt chloride 2.5g, copper sulphate 1g, cold boiling water adds to 1000ml, filter with gauze after mixing, 1Kg body weight 0.25ml, is applied on sow nipple, or is mixed in pig starter feed and drinking-water, every day 1 time, serve on and carries out 10.And add conventional feed normally to feed.

The treatment situation of record experimentation.See table 1.

The average weight of the piglet before and after record experiment, calculates average weight growth pattern.See table 2.

Table 1 is treatment situation contrast (altogether 50) of each group

Can find out see table 1, the healing number of the treatment piglet of functional feed group and cure rate are all higher than healing number and the cure rate of the piglet of control group, can learn, functional feed of the present invention, in the not optimum anaemia for the treatment of piglet nutrition, result for the treatment of is good, and determined curative effect well improves the state of an illness.

Table 2 is the balanced growth body weight contrast of the piglet of each group

Can find out see table 2, while the not optimum anaemia for the treatment of piglet nutrition of functional feed group, growth rate all faster than control group, will maintain the normal growth of piglet.

In sum, functional feed of the present invention, in the not optimum anaemia for the treatment of piglet nutrition, result for the treatment of is good, determined curative effect, and ensure that the normal growth of piglet.

Citing: piglet 1000 is given birth on Dezhou City pig farm, in August, 2013,200 symptoms occurring the not optimum anaemia of piglet nutrition: sick pig spirit is depressed, peels off and lies prostrate, anorexia, inverse vertical by hair, lack gloss, poor growth or stopping.Body temperature is not high, accompanies diarrhoea more.Visual mucous membrane look light, slight xanthochromia or pale.Illumination auricular concha is canescence, almost can not see obvious blood vessel, and acupuncture is also seldom hemorrhage.Breathe and increase number, pulse rapidly, can hear anemicus intracardial accentuated; Light exercise then heartbeat is prosperous and powerful, gasps for breath.Can there is oedema in head and front body, sometimes phrenospasm occurs.Some piglet outward appearances are very fat, grow also very fast, can die by visitation of God in running.Some piglet outward appearances are become thin, and constipation diarrhea alternately occurs, different from, exhaustion; Stomach wall is crispaturaed, and its build is olive-shaped.Select 80 ill piglets to isolate for treatment, select the functional feed of embodiment 2 normally to feed, treat 10, be effectively 78, efficient 97.5%.Body weight increases 6.35kg at treatments period.

The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (9)

1. one kind for preventing the functional feed of the not optimum anaemia of piglet nutrition, it is characterized in that, described functional feed comprises following raw material: corn flour, powder of straw, soya-bean cake, stir-bake to yellowish bean powder, bone meal, Bei Fen, salt, fish meal, carrot, taro, wheat bran, Chinese sorghum face, the dish dregs of rice, trace mineral supplement and lysine.

2. according to claim 1 for preventing the functional feed of the not optimum anaemia of piglet nutrition, it is characterized in that, in described functional feed, the parts by weight of each raw material are: corn flour 25-40 weight portion, powder of straw 10-15 weight portion, soya-bean cake 5-10 weight portion, stir-bake to yellowish bean powder 12-26 weight portion, bone meal 10-25 weight portion, shellfish powder 10-20 weight portion, salt 1-3 weight portion, fish meal 5-10 weight portion, carrot 4-8 weight portion, taro 5-9 weight portion, wheat bran 15-20 weight portion, Chinese sorghum face 15-20 weight portion, dish dregs of rice 7-13 weight portion, trace mineral supplement 0.001-0.5 weight portion and lysine 0.01-0.2 weight portion.

3. according to claim 1 and 2 for preventing the functional feed of the not optimum anaemia of piglet nutrition, it is characterized in that, described functional feed also comprises Chinese medicine additive, in described feed, the parts by weight of each raw material are: corn flour 25-40 weight portion, powder of straw 10-15 weight portion, soya-bean cake 5-10 weight portion, stir-bake to yellowish bean powder 12-26 weight portion, bone meal 10-25 weight portion, shellfish powder 10-20 weight portion, salt 1-3 weight portion, fish meal 5-10 weight portion, carrot 4-8 weight portion, taro 5-9 weight portion, wheat bran 15-20 weight portion, Chinese sorghum face 15-20 weight portion, dish dregs of rice 7-13 weight portion, trace mineral supplement 0.001-0.5 weight portion, lysine 0.01-0.2 weight portion and Chinese medicine additive 6-12 weight portion.

4. the functional feed for preventing the not optimum anaemia of piglet nutrition according to any one of claim 1-3, it is characterized in that, in described functional feed, the parts by weight of each raw material are: corn flour 40 weight portion, powder of straw 15 weight portion, soya-bean cake 10 weight portion, stir-bake to yellowish bean powder 26 weight portion, bone meal 25 weight portion, shellfish powder 20 weight portion, salt 3 weight portion, fish meal 10 weight portion, carrot 8 weight portion, taro 9 weight portion, wheat bran 20 weight portion, Chinese sorghum face 20 weight portion, the dish dregs of rice 13 weight portion, trace mineral supplement 0.01 weight portion, lysine 0.05 weight portion and Chinese medicine additive 7 weight portion.

5. the functional feed for preventing the not optimum anaemia of piglet nutrition according to any one of claim 1-4, it is characterized in that, described Chinese medicine additive comprises following raw medicinal material: Radix Glycyrrhizae, fushen, polygala root, spina date seed, the banksia rose, arillus longan, date, the pig iron fall, magnetite, dark plum, the fruit of Chinese magnoliavine, silkworm chrysalis, laver, tortoise plastron, turtle shell, light wheat, cuttlebone, citron, walnut kernel, pine nut, the membrane of a chicken's gizzard, cultivated land, prepared fleece flower root, donkey-hide gelatin, fructus amomi, ventilago leiocarpa, Wilson Begonia Rhizome.

6. the functional feed for preventing the not optimum anaemia of piglet nutrition according to any one of claim 1-5, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: Radix Glycyrrhizae 10-25 weight portion, fushen 10-20 weight portion, polygala root 10-15 weight portion, spina date seed 10-25 weight portion, banksia rose 5-8 weight portion, arillus longan 15-26 weight portion, date 20-30 weight portion, the pig iron falls 10-18 weight portion, magnetite 10-15 weight portion, dark plum 10-14 weight portion, fruit of Chinese magnoliavine 10-20 weight portion, silkworm chrysalis 13-26 weight portion, laver 20-30 weight portion, tortoise plastron 7-12 weight portion, turtle shell 6-12 weight portion, light wheat 10-20 weight portion, cuttlebone 12-23 weight portion, citron 10-20 weight portion, walnut kernel 20-30 weight portion, pine nut 18-24 weight portion, the membrane of a chicken's gizzard 10-19 weight portion, cultivated land 12-23 weight portion, fleece-flower root 13-20 weight portion, donkey-hide gelatin 25-35 weight portion, fructus amomi 10-16 weight portion, ventilago leiocarpa 12-24 weight portion, Wilson Begonia Rhizome 10-20 weight portion.

7. the functional feed for preventing the not optimum anaemia of piglet nutrition according to any one of claim 1-6, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: Radix Glycyrrhizae 25 weight portion, fushen 20 weight portion, polygala root 15 weight portion, spina date seed 25 weight portion, the banksia rose 8 weight portion, arillus longan 26 weight portion, date 30 weight portion, the pig iron falls 18 weight portions, magnetite 15 weight portion, dark plum 14 weight portion, the fruit of Chinese magnoliavine 20 weight portion, silkworm chrysalis 26 weight portion, laver 30 weight portion, tortoise plastron 12 weight portion, turtle shell 12 weight portion, light wheat 20 weight portion, cuttlebone 23 weight portion, citron 20 weight portion, walnut kernel 30 weight portion, pine nut 24 weight portion, the membrane of a chicken's gizzard 19 weight portion, cultivated land 23 weight portion, the fleece-flower root 20 weight portion, donkey-hide gelatin 35 weight portion, fructus amomi 16 weight portion, ventilago leiocarpa 24 weight portion, Wilson Begonia Rhizome 20 weight portion.

8. the functional feed for preventing the not optimum anaemia of piglet nutrition according to any one of claim 1-7, it is characterized in that, the preparation method of described Chinese medicine additive comprises the following steps:

The first step, mixes in proportion by described raw medicinal material, and adding relative to the determining alcohol of mixture quality 3 ~ 5 times is the ethanol of 80 ~ 90%, adds hot reflux 1 ~ 3 hour, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 1 ~ 2 times to be again the ethanol of 80 ~ 90%, to add hot reflux 1 ~ 3 hour that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;

Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;

3rd step, adds the starch relative to its quality 2 ~ 4 times in the micropowders obtained by second step, mixing, obtains powder.

9. the preparation method of the functional feed for preventing the not optimum anaemia of piglet nutrition according to any one of claim 1-8, it is characterized in that, described preparation method comprises the following steps:

(1) broken raw material stage: take by ratio of weight and the number of copies soya-bean cake, carrot, taro, wheat bran, the dish dregs of rice drop into pulverizer carry out Crushing of Ultrafine, through pulverizing after cross 3.2mm sieve, obtain fine powder;

(2) mixed material step: take corn flour, powder of straw, stir-bake to yellowish bean powder, bone meal, Bei Fen, salt, fish meal, Chinese sorghum face, trace mineral supplement, lysine and Chinese medicine additive according to ratio of weight and number, pulverize with step (1) fine powder obtained to mix, drop into mixer, mix, incorporation time is 45-80s;

(3) feed granules step is manufactured: drop into granulator and granulate, pelleting temperature is 70 DEG C-80 DEG C, makes its gelatinization degree reach more than 94%;

(4) dry feed step: the feed granules obtained by (3) step, under temperature is 35-45 DEG C of environment, carries out air-dry airing, obtains functional feed.