KR20020069129A - 니코틴 분해용 기능성 제제 및 그의 제조방법 - Google Patents
니코틴 분해용 기능성 제제 및 그의 제조방법 Download PDFInfo
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- KR20020069129A KR20020069129A KR1020020009104A KR20020009104A KR20020069129A KR 20020069129 A KR20020069129 A KR 20020069129A KR 1020020009104 A KR1020020009104 A KR 1020020009104A KR 20020009104 A KR20020009104 A KR 20020009104A KR 20020069129 A KR20020069129 A KR 20020069129A
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medical Informatics (AREA)
- Animal Behavior & Ethology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
1차 | 2차 | 3차 | 4차 | 5차 | ||
대조군 | 그룹1 코티닌 평균값(μM) | 16.46 | 10.84 | 12.59 | 13.84 | 9.98 |
그룹2 코티닌 평균값(μM) | 34.86 | 15.48 | 21.49 | 28.59 | 19.14 | |
그룹1 코티닌 평균값(μM) | 19.29 | 11.95 | 18.51 | 18.88 | 16.32 | |
그룹2 코티닌 평균값(μM) | 42.26 | 31.37 | 32.72 | 36.72 | 25.48 | |
그룹1 코티닌 증가율(%) | 17.2 | 10.2 | 47.0 | 36.4 | 63.5 | |
그룹2 코티닌 증가율(%) | 21.2 | 102.6 | 52.3 | 28.4 | 33.1 |
본 검 | 맹 검 | |||
검체(S) | 공실험(Bl) | 검체공실험(S-Bl) | 시약공실험(Bl-Bl) | |
시료 | 0.1 ㎖ (시료물질) | 0.1 ㎖ (증류수) | 0.1 ㎖ (시료물질) | 0.1 ㎖ (증류수) |
발색액 | 1 ㎖ | 1 ㎖ | 1 ㎖ | 1 ㎖ |
효소액 | 1 ㎖ | 1 ㎖ | - | - |
공실험액 | - | - | 1 ㎖ | 1 ㎖ |
N-그룹 | 1 | 2 | 3 | 4 | 5 | |||||||||
폐(절편수) | N(15) | N(16) | N(15) | N(15) | N(15) | |||||||||
간 | N | N | N | N | N | |||||||||
위 | N | N | N | N | N | |||||||||
C-그룹 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | sum | total | ||
폐 | 절편수 | 14 | 14 | 14 | 15 | 14 | 16 | 15 | 13 | 14 | 15 | 144 | 144 | |
아데노마 | 0/2 | 6/5 | 2/4 | 1/3 | 5/7 | 3/9 | 1/4 | 3/4 | 6/7 | 4/4 | 31/49 | 80 | ||
하이퍼플라시아 | 2/5 | 4/4 | 1/6 | 6/7 | 2/8 | 3/6 | 5/6 | 6/6 | 3/7 | 4/9 | 39/64 | 100 | ||
간 | N | - | N | N | - | N | N | N | - | N | ||||
마이크로그래뉼로마 | - | + | - | - | +++ | - | - | - | + | - | ||||
위 | N | N | N | N | N | N | N | N | N | N | ||||
T-그룹 | 폐 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | sum | total | ||
절편수 | 14 | 14 | 14 | 14 | 15 | 14 | 14 | 15 | 12 | 126 | 126 | |||
아데노마 | 1/5 | 2/5 | 2/8 | 3/4 | 4/2 | 6/1 | 0/3 | 1/2 | 3/3 | 22/23 | 55 | |||
하이퍼플라시아 | 0/5 | 2/11 | 7/5 | 1/2 | 2/6 | 2/5 | 2/1 | 2/3 | 1/2 | 19/40 | 59 | |||
간 | - | - | N | - | - | N | N | N | N | |||||
마이크로그래뉼로마 | - | - | - | + | +++ | - | - | - | - | |||||
위 | N | N | N | N | N | N | N | N | N |
그룹 | 성 | 동물수 | 번호 | 투여액의 부피(ml/kg) | 투여량(mg/kg) |
대조군(물) | 수컷 | 5 | 1-5 | 10 | 0 |
암컷 | 5 | 21-25 | 10 | 0 | |
T1 | 수컷 | 5 | 6-10 | 10 | 800 |
암컷 | 5 | 26-30 | 10 | 800 | |
T2 | 수컷 | 5 | 11-15 | 10 | 2000 |
암컷 | 5 | 31-35 | 10 | 2000 | |
T3 | 수컷 | 5 | 16-20 | 10 | 5000 |
암컷 | 5 | 36-40 | 10 | 5000 |
Claims (6)
- (a) 50 내지 500 중량부의 녹차엽에서 추출한 녹차유효성분의 가루분말;(b) 7.5 내지 75 중량부의 상엽을 끓는 물에서 우려낸 추출액;(c) 3 내지 30 중량부의 사과를 즙으로 만든 액;(d) 3 내지 30 중량부의 감초를 끓는 물에서 우려낸 추출액; 및(e) 1.5 내지 15 중량부의 진피를 끓는 물에서 우려낸 추출액;을 포함하는 혼합물을 건조하여 제조하는 것을 특징으로 하는 니코틴 분해용 조성물.
- 제 1항에 있어서, 상기 니코틴 분해용 기능성 제제는(a) 7.5 내지 75 중량부의 은행을 즙으로 만든 액;(b) 3 내지 30 중량부의 샐러리를 즙으로 만든 액; 및(c) 3 내지 30 중량부의 레몬을 즙으로 만든 액;을 더욱 포함하는 혼합물을 건조하여 제조하는 것을 특징으로 하는 니코틴 분해용 조성물.
- 제 1항에 있어서, 상기 니코틴 분해용 조성물은 식품, 식품첨가제, 약제, 음료, 또는 음료첨가제로 사용되어지는 것을 특징으로 하는 니코틴 분해용 조성물.
- 제 1항 내지 제 2항에 있어서, 상기 니코틴 분해용 제제는 포장하여 캡슐화한 것임을 특징으로 하는 니코틴 분해용 기능성 제제.
- 제 1항의 조성물 0.1 내지 0.8 중량%에 물을 혼합하여 제조하는 것을 특징으로 하는 니코틴 분해용 기능성 음료.
- (a) 은행, 샐러리, 사과 및 레몬을 착즙하고 여과하여 과채류 여과액을 제조하는 과채류 여과액 제조단계;(b) 감초, 진피를 100 ℃에서 추출한 다음 상엽을 더욱 혼합하여 재추출하여 여과함으로써 한약재 농축액을 제조하는 엽류 및 한약재 농축액 제조단계; 및(c) 상기 (a)의 과채류 여과액, 상기 (b)의 엽류 및 한약재 농축액, 및 녹차 유효성분인 분말가루를 혼합하여 여과한 다음 분사건조하는 분말제조단계;를 포함하는 것을 특징으로 하는 니코틴 분해용 기능성 제제 제조방법.
Priority Applications (6)
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EP02703981A EP1392133A2 (en) | 2001-02-21 | 2002-02-21 | Functional agent for decomposing nicotine and method of preparing the same |
CNB028053273A CN1255049C (zh) | 2001-02-21 | 2002-02-21 | 用于分解烟碱的功能药剂及其制备方法 |
AU2002237578A AU2002237578A1 (en) | 2001-02-21 | 2002-02-21 | Functional agent for decomposing nicotine and method of preparing the same |
US10/468,500 US7037533B2 (en) | 2001-02-21 | 2002-02-21 | Functional agent for decomposing nicotine and method of preparing the same |
PCT/KR2002/000280 WO2002065978A2 (en) | 2001-02-21 | 2002-02-21 | Functional agent for decomposing nicotine and method of preparing the same |
JP2002565539A JP4820531B2 (ja) | 2001-02-21 | 2002-02-21 | ニコチン分解用機能性製剤およびその製造方法 |
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KR1020010008602 | 2001-02-21 | ||
KR20010008602 | 2001-02-21 |
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KR20020069129A true KR20020069129A (ko) | 2002-08-29 |
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JP (1) | JP4820531B2 (ko) |
KR (1) | KR100464140B1 (ko) |
RU (1) | RU2254031C2 (ko) |
Cited By (5)
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KR20030077121A (ko) * | 2002-03-25 | 2003-10-01 | 주식회사 퓨쳐바이오테크 | 흡연에 의한 암 예방조성물 |
KR100470957B1 (ko) * | 2002-08-26 | 2005-02-22 | 임선 | 담배의 제조방법 |
KR100526760B1 (ko) * | 2003-09-05 | 2005-11-08 | 김현석 | 체내 니코틴 분해 효과와 다이옥신의 독성을 감소시키는 효과를 가지는 생약재 추출물의 조성물 |
KR100626398B1 (ko) * | 2005-03-11 | 2006-09-20 | 박선호 | 흡연자 및 흡연경력자를 위한 항산화영양소 보충 조성물 및그 제조방법 |
CN103623099A (zh) * | 2013-11-28 | 2014-03-12 | 王未境 | 一种用于痛风的甜茶 |
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CN103349330B (zh) * | 2013-07-22 | 2015-08-05 | 防城港市天红农业科技有限责任公司 | 一种莲雾饮料及其制备方法 |
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JP3163161B2 (ja) * | 1992-04-24 | 2001-05-08 | 丸善製薬株式会社 | 発癌プロモーション抑制剤 |
JP3536111B2 (ja) * | 1992-06-29 | 2004-06-07 | 株式会社ナリス化粧品 | ムコ多糖類断片化抑制剤および化粧料 |
CN1030423C (zh) * | 1993-08-27 | 1995-12-06 | 沈阳市东方医疗保健品研究所 | 解烟保健茶 |
JPH07126180A (ja) * | 1993-11-01 | 1995-05-16 | Daicel Chem Ind Ltd | 発癌抑制剤 |
JPH08259453A (ja) * | 1993-12-06 | 1996-10-08 | Nikka Uisukii Kk | 果実ポリフェノール含有果汁とその製造方法、酸化防止剤、血圧降下剤、抗変異原性作用剤、アレルギー抑制剤、抗う蝕剤及び消臭剤 |
CN1100322A (zh) * | 1994-03-28 | 1995-03-22 | 宋小龙 | 烟宝 |
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JP3326589B2 (ja) * | 1996-10-26 | 2002-09-24 | 祥之 亀山 | 桑葉、梅肉、梅仁、紫蘇葉等を素材とする健康食品 |
JPH119217A (ja) * | 1997-06-27 | 1999-01-19 | Yakult Honsha Co Ltd | パセリ又はセロリの透明搾汁液の製造方法 |
US5829449A (en) * | 1997-09-19 | 1998-11-03 | Thione International, Inc. | Smoking products containing antioxidants |
KR100581216B1 (ko) * | 1998-12-31 | 2006-08-18 | 주식회사 태평양 | 니코틴 제거효과가 있는 기호성이 우수한 혼합차 |
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KR100446641B1 (ko) * | 1999-07-16 | 2004-09-04 | 주식회사 리젠 바이오텍 | 니코틴 분해음료 및 제재 |
KR100352030B1 (en) * | 2002-01-10 | 2002-09-11 | Orion Corp | Gum composition for removing nicotine |
KR101100322B1 (ko) * | 2009-02-23 | 2011-12-30 | 위슨정보통신주식회사 | 기둥용 커버 |
KR101084018B1 (ko) * | 2009-12-22 | 2011-11-16 | 연세대학교 산학협력단 | 국소 표면 플라즈몬 공명 기반의 초고해상도 전반사 형광 현미경 및 전반사 형광 현미경용 검출 모듈 |
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- 2002-02-21 RU RU2003124505/13A patent/RU2254031C2/ru not_active IP Right Cessation
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030077121A (ko) * | 2002-03-25 | 2003-10-01 | 주식회사 퓨쳐바이오테크 | 흡연에 의한 암 예방조성물 |
KR100470957B1 (ko) * | 2002-08-26 | 2005-02-22 | 임선 | 담배의 제조방법 |
KR100526760B1 (ko) * | 2003-09-05 | 2005-11-08 | 김현석 | 체내 니코틴 분해 효과와 다이옥신의 독성을 감소시키는 효과를 가지는 생약재 추출물의 조성물 |
KR100626398B1 (ko) * | 2005-03-11 | 2006-09-20 | 박선호 | 흡연자 및 흡연경력자를 위한 항산화영양소 보충 조성물 및그 제조방법 |
CN103623099A (zh) * | 2013-11-28 | 2014-03-12 | 王未境 | 一种用于痛风的甜茶 |
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Publication number | Publication date |
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KR100464140B1 (ko) | 2005-01-03 |
RU2254031C2 (ru) | 2005-06-20 |
JP4820531B2 (ja) | 2011-11-24 |
JP2004526708A (ja) | 2004-09-02 |
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