KR20020005623A - 페닐 글리옥실산 에스테르 옥심의 제조방법 - Google Patents
페닐 글리옥실산 에스테르 옥심의 제조방법 Download PDFInfo
- Publication number
- KR20020005623A KR20020005623A KR1020017011987A KR20017011987A KR20020005623A KR 20020005623 A KR20020005623 A KR 20020005623A KR 1020017011987 A KR1020017011987 A KR 1020017011987A KR 20017011987 A KR20017011987 A KR 20017011987A KR 20020005623 A KR20020005623 A KR 20020005623A
- Authority
- KR
- South Korea
- Prior art keywords
- alkyl
- formula
- salt
- aryl
- copper
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
- C07C249/12—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reactions not involving the formation of oxyimino groups
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims (7)
- (1) 하기 일반식 (II)의 아닐린을 유기 또는 무기 나이트라이트 또는 아질산으로 디아조화시키고;(2) 생성된 디아조늄염을 구리(II)-염의 존재하에서 하기 일반식 (III)의 옥심과 반응시킴을 특징으로 하여, 하기 일반식 (I)의 화합물을 제조하는 방법:상기 식에서,R1은 임의로 치환된 알킬이고,R2는 각각 알킬, 알콕시 또는 할로겐에 의해 임의로 치환된 C1-C6-알킬, C3-C6-사이클로알킬, C3-C6-사이클로알킬-C1-C2-알킬, 아릴, 아릴-C1-C2-알킬, 헤테로사이클릴 또는 헤테로사이클릴-C1-C2-알킬이다.
- 제 1 항에 있어서, 구리(II)-염이 CuCl2또는 CuSO4인 방법.
- 제 1 항에 있어서, 구리(II)-염의 양이 일반식 (II)의 화합물에 대해 1 내지 30 몰%인 방법.
- 제 1 항에 있어서, 반응 단계 (2)에서 디아조늄염을 환원제의 존재하에서 반응시키는 방법.
- 제 4 항에 있어서, 환원제가 소듐 설파이트 또는 포타슘 설파이트인 방법.
- 제 1 항에 있어서, 일반식 (I), (II) 및 (III)에서 R1이 메틸이고, R2가 메틸 또는 에틸인 방법.
- (1) 일반식 (II.1)의 아닐린을 유기 또는 무기 나이트라이트 또는 아질산으로 디아조화시키고;(2) 생성된 디아조늄염을 구리(II)-염의 존재하에서 일반식 (III)의 옥심과 반응시킨 후;(3) 생성된 일반식 (I.1)의 옥심을 메틸화시키며;(4) 생성된 일반식 (IV.1)의 옥심 에테르를 할로겐화시킴을 특징으로 하여, 일반식 (V.1)의 화합물을 제조하는 방법:상기에서,R2는 각각 알킬, 알콕시 또는 할로겐에 의해 임의로 치환된 C1-C6-알킬, C3-C6-사이클로알킬, C3-C6-사이클로알킬-C1-C2-알킬, 아릴, 아릴-C1-C2-알킬, 헤테로사이클릴 또는 헤테로사이클릴-C1-C2-알킬이다.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9908530.0A GB9908530D0 (en) | 1999-04-14 | 1999-04-14 | Organic compounds |
GB9908530.0 | 1999-04-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20020005623A true KR20020005623A (ko) | 2002-01-17 |
KR100662632B1 KR100662632B1 (ko) | 2007-01-02 |
Family
ID=10851522
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020017011987A KR100662632B1 (ko) | 1999-04-14 | 2000-04-12 | 페닐 글리옥실산 에스테르 옥심의 제조방법 |
Country Status (16)
Country | Link |
---|---|
US (1) | US6670496B1 (ko) |
EP (1) | EP1173410B1 (ko) |
JP (1) | JP4049536B2 (ko) |
KR (1) | KR100662632B1 (ko) |
CN (1) | CN1158247C (ko) |
AT (1) | ATE252548T1 (ko) |
AU (1) | AU4548100A (ko) |
BR (1) | BR0009691B1 (ko) |
DE (1) | DE60006093T2 (ko) |
DK (1) | DK1173410T3 (ko) |
ES (1) | ES2209872T3 (ko) |
GB (1) | GB9908530D0 (ko) |
HK (1) | HK1043984A1 (ko) |
IL (1) | IL145377A0 (ko) |
MX (1) | MXPA01010362A (ko) |
WO (1) | WO2000063162A1 (ko) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112020004825B1 (pt) * | 2017-09-11 | 2023-11-14 | Hikal Limited | Processo aperfeiçoado para a preparação de trifloxistrobina |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3623921A1 (de) | 1986-07-16 | 1988-01-21 | Basf Ag | Oximether und diese enthaltende fungizide |
USRE33989E (en) | 1986-07-16 | 1992-07-07 | Basf Aktiengesellschaft | Oxime ethers and fungicides containing these compounds |
ATE141589T1 (de) | 1989-05-17 | 1996-09-15 | Shionogi & Co | Alkoxyiminoacetamid-derivate und ihre verwendung als pilztötendes mittel |
PH11991042549B1 (ko) | 1990-06-05 | 2000-12-04 | ||
HU219157B (hu) | 1994-01-05 | 2001-02-28 | Novartis Ag. | Peszticid hatású [dioxa-diaza/vagy oxa-triaza/-heptadienil-fenil]-akrilsav- és glioxilsav-származékok, előállításuk és alkalmazásuk |
DK0782982T3 (da) | 1996-01-03 | 2000-10-09 | Novartis Ag | Fremgangsmåde til fremstilling af o-chlormethyl-phenylglyoxylsyrederivater |
DE19719054A1 (de) | 1997-05-06 | 1998-11-12 | Bayer Ag | Verfahren zur Herstellung von Acetophenonen, die am aromatischen Kern mit Fluoralkyl substituiert sind |
-
1999
- 1999-04-14 GB GBGB9908530.0A patent/GB9908530D0/en not_active Ceased
-
2000
- 2000-04-12 AU AU45481/00A patent/AU4548100A/en not_active Abandoned
- 2000-04-12 KR KR1020017011987A patent/KR100662632B1/ko active IP Right Grant
- 2000-04-12 DE DE60006093T patent/DE60006093T2/de not_active Expired - Lifetime
- 2000-04-12 AT AT00926893T patent/ATE252548T1/de active
- 2000-04-12 IL IL14537700A patent/IL145377A0/xx not_active IP Right Cessation
- 2000-04-12 CN CNB008062048A patent/CN1158247C/zh not_active Expired - Lifetime
- 2000-04-12 BR BRPI0009691-1A patent/BR0009691B1/pt not_active IP Right Cessation
- 2000-04-12 JP JP2000612258A patent/JP4049536B2/ja not_active Expired - Lifetime
- 2000-04-12 MX MXPA01010362A patent/MXPA01010362A/es unknown
- 2000-04-12 DK DK00926893T patent/DK1173410T3/da active
- 2000-04-12 US US09/958,715 patent/US6670496B1/en not_active Expired - Lifetime
- 2000-04-12 WO PCT/EP2000/003289 patent/WO2000063162A1/en active IP Right Grant
- 2000-04-12 ES ES00926893T patent/ES2209872T3/es not_active Expired - Lifetime
- 2000-04-12 EP EP00926893A patent/EP1173410B1/en not_active Expired - Lifetime
-
2002
- 2002-08-01 HK HK02105677.7A patent/HK1043984A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
JP4049536B2 (ja) | 2008-02-20 |
DK1173410T3 (da) | 2004-02-23 |
EP1173410A1 (en) | 2002-01-23 |
BR0009691A (pt) | 2002-01-08 |
DE60006093T2 (de) | 2004-07-22 |
JP2002542225A (ja) | 2002-12-10 |
WO2000063162A1 (en) | 2000-10-26 |
ATE252548T1 (de) | 2003-11-15 |
CN1347405A (zh) | 2002-05-01 |
IL145377A0 (en) | 2002-06-30 |
EP1173410B1 (en) | 2003-10-22 |
AU4548100A (en) | 2000-11-02 |
DE60006093D1 (de) | 2003-11-27 |
MXPA01010362A (es) | 2002-05-06 |
CN1158247C (zh) | 2004-07-21 |
ES2209872T3 (es) | 2004-07-01 |
US6670496B1 (en) | 2003-12-30 |
KR100662632B1 (ko) | 2007-01-02 |
GB9908530D0 (en) | 1999-06-09 |
HK1043984A1 (zh) | 2002-10-04 |
BR0009691B1 (pt) | 2010-11-16 |
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