KR20010043942A - 아목시실린의 결정질 염의 제조 방법 - Google Patents

아목시실린의 결정질 염의 제조 방법 Download PDF

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Publication number
KR20010043942A
KR20010043942A KR1020007013513A KR20007013513A KR20010043942A KR 20010043942 A KR20010043942 A KR 20010043942A KR 1020007013513 A KR1020007013513 A KR 1020007013513A KR 20007013513 A KR20007013513 A KR 20007013513A KR 20010043942 A KR20010043942 A KR 20010043942A
Authority
KR
South Korea
Prior art keywords
salt
amoxicillin
solution
amine
sodium
Prior art date
Application number
KR1020007013513A
Other languages
English (en)
Korean (ko)
Inventor
폴 지. 버터리
에신 에프. 코살
Original Assignee
스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스
스미스클라인 비참 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스, 스미스클라인 비참 코포레이션 filed Critical 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스
Publication of KR20010043942A publication Critical patent/KR20010043942A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04—Preparation
    • C07D499/14—Preparation of salts
    • C07D499/16—Preparation of salts of alkali or alkaline earth metals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020007013513A 1998-06-01 1999-06-01 아목시실린의 결정질 염의 제조 방법 KR20010043942A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8755498P 1998-06-01 1998-06-01
US60/087,554 1998-06-01
PCT/US1999/011991 WO1999062910A1 (en) 1998-06-01 1999-06-01 Process for preparing crystalline salts of amoxycillin

Publications (1)

Publication Number Publication Date
KR20010043942A true KR20010043942A (ko) 2001-05-25

Family

ID=22205864

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020007013513A KR20010043942A (ko) 1998-06-01 1999-06-01 아목시실린의 결정질 염의 제조 방법

Country Status (15)

Country Link
EP (1) EP1086109A4 (no)
JP (1) JP2002517398A (no)
KR (1) KR20010043942A (no)
CN (1) CN1182138C (no)
AU (1) AU760934B2 (no)
BR (1) BR9910804A (no)
CA (1) CA2333943A1 (no)
HU (1) HUP0102008A3 (no)
IL (1) IL139736A (no)
NO (1) NO20006073L (no)
NZ (1) NZ508179A (no)
PL (1) PL344348A1 (no)
TR (1) TR200003517T2 (no)
WO (1) WO1999062910A1 (no)
ZA (1) ZA200006946B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294199B1 (en) 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
WO2006072577A1 (en) * 2005-01-07 2006-07-13 Sandoz Ag Process for preparing granulates comprising amoxicillin
CN101633663B (zh) * 2009-08-28 2011-12-21 沈阳顺旺动物药业有限公司 一种青霉素类钠、钾盐的合成方法
CN102971328A (zh) * 2010-06-16 2013-03-13 瓦尔德曼化学科技股份有限公司 用于制备阿莫西林钠的改进方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8606871A1 (es) * 1985-10-21 1986-06-01 Antibioticos Sa Un procedimiento de preparacion de amoxicilina sodica
IT1255716B (it) * 1992-10-05 1995-11-10 Procedimento per la preparazione di antibiotici beta-lattamici sterili
TW347383B (en) * 1995-10-26 1998-12-11 Biochemie Gmbh A process for the production of a crystalline sodium salt of amoxicillin in ethanol as solvent

Also Published As

Publication number Publication date
ZA200006946B (en) 2002-01-28
AU4321699A (en) 1999-12-20
HUP0102008A2 (hu) 2001-12-28
WO1999062910A1 (en) 1999-12-09
HUP0102008A3 (en) 2002-07-29
NO20006073D0 (no) 2000-11-30
IL139736A (en) 2004-02-19
CN1304412A (zh) 2001-07-18
NO20006073L (no) 2000-11-30
IL139736A0 (en) 2002-02-10
CA2333943A1 (en) 1999-12-09
JP2002517398A (ja) 2002-06-18
EP1086109A1 (en) 2001-03-28
AU760934B2 (en) 2003-05-22
EP1086109A4 (en) 2001-12-19
NZ508179A (en) 2002-10-25
PL344348A1 (en) 2001-11-05
BR9910804A (pt) 2001-02-13
CN1182138C (zh) 2004-12-29
TR200003517T2 (tr) 2001-06-21

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Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application