CA2333943A1 - Process for preparing crystalline salts of amoxycillin - Google Patents

Process for preparing crystalline salts of amoxycillin Download PDF

Info

Publication number
CA2333943A1
CA2333943A1 CA002333943A CA2333943A CA2333943A1 CA 2333943 A1 CA2333943 A1 CA 2333943A1 CA 002333943 A CA002333943 A CA 002333943A CA 2333943 A CA2333943 A CA 2333943A CA 2333943 A1 CA2333943 A1 CA 2333943A1
Authority
CA
Canada
Prior art keywords
amoxycillin
process according
salt
solution
sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002333943A
Other languages
English (en)
French (fr)
Inventor
Paul G. Butterly
Esin F. Kosal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2333943A1 publication Critical patent/CA2333943A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04Preparation
    • C07D499/14Preparation of salts
    • C07D499/16Preparation of salts of alkali or alkaline earth metals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002333943A 1998-06-01 1999-06-01 Process for preparing crystalline salts of amoxycillin Abandoned CA2333943A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8755498P 1998-06-01 1998-06-01
US60/087,554 1998-06-01
PCT/US1999/011991 WO1999062910A1 (en) 1998-06-01 1999-06-01 Process for preparing crystalline salts of amoxycillin

Publications (1)

Publication Number Publication Date
CA2333943A1 true CA2333943A1 (en) 1999-12-09

Family

ID=22205864

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002333943A Abandoned CA2333943A1 (en) 1998-06-01 1999-06-01 Process for preparing crystalline salts of amoxycillin

Country Status (15)

Country Link
EP (1) EP1086109A4 (no)
JP (1) JP2002517398A (no)
KR (1) KR20010043942A (no)
CN (1) CN1182138C (no)
AU (1) AU760934B2 (no)
BR (1) BR9910804A (no)
CA (1) CA2333943A1 (no)
HU (1) HUP0102008A3 (no)
IL (1) IL139736A (no)
NO (1) NO20006073D0 (no)
NZ (1) NZ508179A (no)
PL (1) PL344348A1 (no)
TR (1) TR200003517T2 (no)
WO (1) WO1999062910A1 (no)
ZA (1) ZA200006946B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
US6294199B1 (en) 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
JP5227591B2 (ja) * 2005-01-07 2013-07-03 サンド・アクチエンゲゼルシヤフト アモキシシリンを含む粒剤の調製方法
CN101633663B (zh) * 2009-08-28 2011-12-21 沈阳顺旺动物药业有限公司 一种青霉素类钠、钾盐的合成方法
MX2012014758A (es) * 2010-06-16 2013-10-01 Vardhman Chemtech Ltd Proceso mejorado para preparar amoxicilina sodica.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8606871A1 (es) * 1985-10-21 1986-06-01 Antibioticos Sa Un procedimiento de preparacion de amoxicilina sodica
IT1255716B (it) * 1992-10-05 1995-11-10 Procedimento per la preparazione di antibiotici beta-lattamici sterili
TW347383B (en) * 1995-10-26 1998-12-11 Biochemie Gmbh A process for the production of a crystalline sodium salt of amoxicillin in ethanol as solvent

Also Published As

Publication number Publication date
NO20006073L (no) 2000-11-30
AU4321699A (en) 1999-12-20
IL139736A (en) 2004-02-19
ZA200006946B (en) 2002-01-28
KR20010043942A (ko) 2001-05-25
BR9910804A (pt) 2001-02-13
TR200003517T2 (tr) 2001-06-21
EP1086109A1 (en) 2001-03-28
AU760934B2 (en) 2003-05-22
HUP0102008A3 (en) 2002-07-29
IL139736A0 (en) 2002-02-10
CN1182138C (zh) 2004-12-29
CN1304412A (zh) 2001-07-18
NZ508179A (en) 2002-10-25
JP2002517398A (ja) 2002-06-18
EP1086109A4 (en) 2001-12-19
HUP0102008A2 (hu) 2001-12-28
NO20006073D0 (no) 2000-11-30
WO1999062910A1 (en) 1999-12-09
PL344348A1 (en) 2001-11-05

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued