KR19990076637A - 비타민 d 유사체를 함유하는 제약 조성물 - Google Patents

비타민 d 유사체를 함유하는 제약 조성물 Download PDF

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Publication number
KR19990076637A
KR19990076637A KR1019980704745A KR19980704745A KR19990076637A KR 19990076637 A KR19990076637 A KR 19990076637A KR 1019980704745 A KR1019980704745 A KR 1019980704745A KR 19980704745 A KR19980704745 A KR 19980704745A KR 19990076637 A KR19990076637 A KR 19990076637A
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KR
South Korea
Prior art keywords
group
vitamin
formula
hydrogen atom
pharmaceutical composition
Prior art date
Application number
KR1019980704745A
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English (en)
Korean (ko)
Inventor
카린 호프만
유타 리들
Original Assignee
덴크, 브뤼크너
쉐링 악티엔게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 덴크, 브뤼크너, 쉐링 악티엔게젤샤프트 filed Critical 덴크, 브뤼크너
Publication of KR19990076637A publication Critical patent/KR19990076637A/ko

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5939,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Nanotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019980704745A 1995-12-21 1996-12-20 비타민 d 유사체를 함유하는 제약 조성물 KR19990076637A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19549243A DE19549243A1 (de) 1995-12-21 1995-12-21 Pharmazeutische Präparate enthaltend Clathrate von Cyclodextrinen und nichtnatürliche Vitamin D-Analoga
DE19549243.9 1995-12-21
PCT/EP1996/005856 WO1997023242A1 (de) 1995-12-21 1996-12-20 Pharmazeutische präparate mit vitamin d-analoga

Publications (1)

Publication Number Publication Date
KR19990076637A true KR19990076637A (ko) 1999-10-15

Family

ID=7781710

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019980704745A KR19990076637A (ko) 1995-12-21 1996-12-20 비타민 d 유사체를 함유하는 제약 조성물

Country Status (12)

Country Link
EP (1) EP0869819A1 (hu)
JP (1) JP2000502733A (hu)
KR (1) KR19990076637A (hu)
CN (1) CN1207687A (hu)
AU (1) AU1306997A (hu)
CA (1) CA2241205A1 (hu)
DE (1) DE19549243A1 (hu)
HU (1) HUP9903935A3 (hu)
IL (1) IL125020A0 (hu)
IS (1) IS4774A (hu)
NO (1) NO982874L (hu)
WO (1) WO1997023242A1 (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6538037B2 (en) 1991-01-08 2003-03-25 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxyvitamin D2
US6566353B2 (en) 1996-12-30 2003-05-20 Bone Care International, Inc. Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US6573256B2 (en) 1996-12-30 2003-06-03 Bone Care International, Inc. Method of inhibiting angiogenesis using active vitamin D analogues
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
GB9826656D0 (en) 1998-12-03 1999-01-27 Novartis Ag Organic compounds
DE102005017775A1 (de) * 2005-04-13 2006-10-19 Schering Ag Komplexe aus Vitamin D-Verbindungen oder deren Analoga mit einem 5Z,7E,10(19)-Trien-System und methlierten Derivaten des ß-Cyclodextrins
LT1993559T (lt) 2006-02-03 2016-11-10 Opko Renal, Llc Vitamino d nepakankamumo ir deficito gydymas su 25-hidroksivitaminu d2 ir 25-hidroksivitaminu d3
PL2037936T3 (pl) 2006-06-21 2015-04-30 Opko Renal Llc Sposób leczenia i zapobiegania wtórnej nadczynności przytarczyc
KR100822133B1 (ko) * 2006-11-06 2008-04-15 한미약품 주식회사 비타민 d 또는 이의 유도체의 고체분산체 및비스포스포네이트를 포함하는, 골다공증 예방 또는 치료용복합제제
KR101495578B1 (ko) 2007-04-25 2015-02-25 사이토크로마 인코포레이티드 비타민 d 부족 및 결핍의 치료 방법
US20100144684A1 (en) 2007-04-25 2010-06-10 Proventiv Therapeutics, Inc. Method of Safely and Effectively Treating and Preventing Secondary Hyperparathyroidism in Chronic Kidney Disease
JP5501956B2 (ja) 2007-04-25 2014-05-28 シトクロマ インコーポレイテッド ビタミンd化合物およびワックス状担体を含有する制御放出性経口組成物
CA2684778C (en) 2007-04-25 2017-09-05 Cytochroma Inc. Methods and compounds for vitamin d therapy
CN106853250A (zh) 2008-04-02 2017-06-16 赛特克罗公司 用于维生素d缺乏症和相关障碍的方法、组合物、用途和试剂盒
CN105796530A (zh) 2010-03-29 2016-07-27 赛特克罗公司 用于降低甲状旁腺水平的方法和组合物
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 d 방출 제형
CN114681468A (zh) 2014-08-07 2022-07-01 欧普科爱尔兰环球控股有限公司 利用25-羟基维生素d的辅助疗法
CR20180510A (es) 2016-03-28 2019-05-15 Opko Ireland Global Holdings Ltd Método de tratamiento con vitamina d

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU177586B (en) * 1978-12-19 1981-11-28 Chinoin Gyogyszer Es Vegyeszet New process for preparing stable inclusion complexes of vitamine d with cyclodextrin
JPS5910562A (ja) * 1982-07-07 1984-01-20 Teijin Ltd プレ−1α−ヒドロキシコレカルシフエロ−ル類の製造法
JPS5936656A (ja) * 1982-08-23 1984-02-28 Teijin Ltd 新規包接化合物及びそれを活性成分とする薬剤
JPS60120812A (ja) * 1983-12-02 1985-06-28 Teijin Ltd 糖尿病性骨減少症治療剤
ATE104554T1 (de) * 1990-01-10 1994-05-15 Hoffmann La Roche Topische praeparate.
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag History of 52-carboxylic acid, processes for their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
AU1306997A (en) 1997-07-17
CN1207687A (zh) 1999-02-10
CA2241205A1 (en) 1997-07-03
IS4774A (is) 1998-06-15
HUP9903935A3 (en) 2000-05-29
NO982874D0 (no) 1998-06-19
WO1997023242A1 (de) 1997-07-03
EP0869819A1 (de) 1998-10-14
NO982874L (no) 1998-08-20
DE19549243A1 (de) 1997-06-26
HUP9903935A2 (hu) 2000-03-28
JP2000502733A (ja) 2000-03-07
IL125020A0 (en) 1999-01-26

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