HUP9903935A2 - D-vitamin analógokat tartalmazó gyógyszerkészítmények - Google Patents
D-vitamin analógokat tartalmazó gyógyszerkészítményekInfo
- Publication number
- HUP9903935A2 HUP9903935A2 HU9903935A HUP9903935A HUP9903935A2 HU P9903935 A2 HUP9903935 A2 HU P9903935A2 HU 9903935 A HU9903935 A HU 9903935A HU P9903935 A HUP9903935 A HU P9903935A HU P9903935 A2 HUP9903935 A2 HU P9903935A2
- Authority
- HU
- Hungary
- Prior art keywords
- analogues
- vitamin
- pharmaceutical compositions
- medicinal preparations
- clathrates
- Prior art date
Links
- 229940046008 vitamin d Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 2
- 229920001353 Dextrin Polymers 0.000 abstract 1
- 239000004375 Dextrin Substances 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 229930003316 Vitamin D Natural products 0.000 abstract 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 1
- 235000020964 calcitriol Nutrition 0.000 abstract 1
- 239000011612 calcitriol Substances 0.000 abstract 1
- GMRQFYUYWCNGIN-NKMMMXOESA-N calcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C GMRQFYUYWCNGIN-NKMMMXOESA-N 0.000 abstract 1
- 229960005084 calcitriol Drugs 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 235000019425 dextrin Nutrition 0.000 abstract 1
- 235000019166 vitamin D Nutrition 0.000 abstract 1
- 239000011710 vitamin D Substances 0.000 abstract 1
- 150000003710 vitamin D derivatives Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Abstract
A találmány tárgyát ciklődextrin-klatrátőkat és D-vitamin-analógőkatmint kalcitriőlt tartalmazó tőpikűsan alkalmazható,gyógyszerkészítmények képezik. A találmány szerintigyógyszerkészítmények psőriasis kezelésére szőlgálnak. ŕ
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19549243A DE19549243A1 (de) | 1995-12-21 | 1995-12-21 | Pharmazeutische Präparate enthaltend Clathrate von Cyclodextrinen und nichtnatürliche Vitamin D-Analoga |
PCT/EP1996/005856 WO1997023242A1 (de) | 1995-12-21 | 1996-12-20 | Pharmazeutische präparate mit vitamin d-analoga |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP9903935A2 true HUP9903935A2 (hu) | 2000-03-28 |
HUP9903935A3 HUP9903935A3 (en) | 2000-05-29 |
Family
ID=7781710
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9903935A HUP9903935A3 (en) | 1995-12-21 | 1996-12-20 | Pharmaceutical compositions with vitamin d analogues |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0869819A1 (hu) |
JP (1) | JP2000502733A (hu) |
KR (1) | KR19990076637A (hu) |
CN (1) | CN1207687A (hu) |
AU (1) | AU1306997A (hu) |
CA (1) | CA2241205A1 (hu) |
DE (1) | DE19549243A1 (hu) |
HU (1) | HUP9903935A3 (hu) |
IL (1) | IL125020A0 (hu) |
IS (1) | IS4774A (hu) |
NO (1) | NO982874L (hu) |
WO (1) | WO1997023242A1 (hu) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6538037B2 (en) | 1991-01-08 | 2003-03-25 | Bone Care International, Inc. | Methods for preparation and use of 1α,24(S)-dihydroxyvitamin D2 |
US6503893B2 (en) | 1996-12-30 | 2003-01-07 | Bone Care International, Inc. | Method of treating hyperproliferative diseases using active vitamin D analogues |
US6566353B2 (en) | 1996-12-30 | 2003-05-20 | Bone Care International, Inc. | Method of treating malignancy associated hypercalcemia using active vitamin D analogues |
US6573256B2 (en) | 1996-12-30 | 2003-06-03 | Bone Care International, Inc. | Method of inhibiting angiogenesis using active vitamin D analogues |
GB9826656D0 (en) | 1998-12-03 | 1999-01-27 | Novartis Ag | Organic compounds |
DE102005017775A1 (de) * | 2005-04-13 | 2006-10-19 | Schering Ag | Komplexe aus Vitamin D-Verbindungen oder deren Analoga mit einem 5Z,7E,10(19)-Trien-System und methlierten Derivaten des ß-Cyclodextrins |
ES2904546T3 (es) | 2006-02-03 | 2022-04-05 | Opko Renal Llc | Tratamiento de la insuficiencia y deficiencia de vitamina D con 25-hidroxivitamina D2 y 25-hidroxivitamina D3 |
WO2008008608A2 (en) | 2006-06-21 | 2008-01-17 | Proventiv Therapeutics, Llc | Method of treating and preventing secondary hyperparathyroidism |
KR100822133B1 (ko) * | 2006-11-06 | 2008-04-15 | 한미약품 주식회사 | 비타민 d 또는 이의 유도체의 고체분산체 및비스포스포네이트를 포함하는, 골다공증 예방 또는 치료용복합제제 |
JP5444212B2 (ja) | 2007-04-25 | 2014-03-19 | シトクロマ インコーポレイテッド | ビタミンd不足および欠乏症の治療方法 |
US20100144684A1 (en) | 2007-04-25 | 2010-06-10 | Proventiv Therapeutics, Inc. | Method of Safely and Effectively Treating and Preventing Secondary Hyperparathyroidism in Chronic Kidney Disease |
WO2008134518A2 (en) | 2007-04-25 | 2008-11-06 | Cytochroma Inc. | Methods and compounds for vitamin d therapy |
PL2148661T3 (pl) | 2007-04-25 | 2013-07-31 | Cytochroma Inc | Doustne kompozycje o kontrolowanym uwalnianiu zawierające związek będący witaminą D i woskowy nośnik |
KR101852042B1 (ko) | 2008-04-02 | 2018-04-25 | 사이토크로마 인코포레이티드 | 비타민 d 결핍 및 관련 장애에 유용한 방법, 조성물, 용도 및 키트 |
ES2783980T3 (es) | 2010-03-29 | 2020-09-21 | Opko Ireland Global Holdings Ltd | Métodos y composiciones para la reducción de niveles de paratiroides |
KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 d 방출 제형 |
SG11201700858RA (en) | 2014-08-07 | 2017-03-30 | Opko Ireland Global Holdings Ltd | Adjunctive therapy with 25-hydroxyvitamin d |
TWI747893B (zh) | 2016-03-28 | 2021-12-01 | 愛爾蘭商歐科愛爾蘭全球控股股份有限公司 | 維生素d治療之方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU177586B (en) * | 1978-12-19 | 1981-11-28 | Chinoin Gyogyszer Es Vegyeszet | New process for preparing stable inclusion complexes of vitamine d with cyclodextrin |
JPS5910562A (ja) * | 1982-07-07 | 1984-01-20 | Teijin Ltd | プレ−1α−ヒドロキシコレカルシフエロ−ル類の製造法 |
JPS5936656A (ja) * | 1982-08-23 | 1984-02-28 | Teijin Ltd | 新規包接化合物及びそれを活性成分とする薬剤 |
JPS60120812A (ja) * | 1983-12-02 | 1985-06-28 | Teijin Ltd | 糖尿病性骨減少症治療剤 |
ATE104554T1 (de) * | 1990-01-10 | 1994-05-15 | Hoffmann La Roche | Topische praeparate. |
IL107185A (en) * | 1992-10-06 | 1998-02-22 | Schering Ag | History of 52-carboxylic acid, processes for their preparation and pharmaceutical preparations containing them |
-
1995
- 1995-12-21 DE DE19549243A patent/DE19549243A1/de not_active Withdrawn
-
1996
- 1996-12-20 IL IL12502096A patent/IL125020A0/xx unknown
- 1996-12-20 CN CN96199734A patent/CN1207687A/zh active Pending
- 1996-12-20 KR KR1019980704745A patent/KR19990076637A/ko not_active Application Discontinuation
- 1996-12-20 JP JP9523335A patent/JP2000502733A/ja active Pending
- 1996-12-20 WO PCT/EP1996/005856 patent/WO1997023242A1/de not_active Application Discontinuation
- 1996-12-20 EP EP96944669A patent/EP0869819A1/de not_active Withdrawn
- 1996-12-20 AU AU13069/97A patent/AU1306997A/en not_active Abandoned
- 1996-12-20 CA CA002241205A patent/CA2241205A1/en not_active Abandoned
- 1996-12-20 HU HU9903935A patent/HUP9903935A3/hu unknown
-
1998
- 1998-06-15 IS IS4774A patent/IS4774A/is unknown
- 1998-06-19 NO NO982874A patent/NO982874L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL125020A0 (en) | 1999-01-26 |
NO982874D0 (no) | 1998-06-19 |
KR19990076637A (ko) | 1999-10-15 |
CN1207687A (zh) | 1999-02-10 |
DE19549243A1 (de) | 1997-06-26 |
NO982874L (no) | 1998-08-20 |
JP2000502733A (ja) | 2000-03-07 |
HUP9903935A3 (en) | 2000-05-29 |
AU1306997A (en) | 1997-07-17 |
WO1997023242A1 (de) | 1997-07-03 |
IS4774A (is) | 1998-06-15 |
EP0869819A1 (de) | 1998-10-14 |
CA2241205A1 (en) | 1997-07-03 |
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