KR102922101B1 - Aav의 검출 방법 - Google Patents

Aav의 검출 방법

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Publication number
KR102922101B1
KR102922101B1 KR1020247039853A KR20247039853A KR102922101B1 KR 102922101 B1 KR102922101 B1 KR 102922101B1 KR 1020247039853 A KR1020247039853 A KR 1020247039853A KR 20247039853 A KR20247039853 A KR 20247039853A KR 102922101 B1 KR102922101 B1 KR 102922101B1
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aav
capsid
gly
pro
ala
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KR20240172773A (ko
Inventor
샤오잉 진
캐서린 알. 오리어던
린 리우
케이트 장
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젠자임 코포레이션
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Application filed by 젠자임 코포레이션 filed Critical 젠자임 코포레이션
Priority to KR1020267003039A priority Critical patent/KR20260036296A/ko
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
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    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
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    • G01N30/02—Column chromatography
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151—Methods of production or purification of viral material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G01N2333/075—Adenoviridae

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  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020247039853A 2016-08-15 2017-08-14 Aav의 검출 방법 Active KR102922101B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020267003039A KR20260036296A (ko) 2016-08-15 2017-08-14 Aav의 검출 방법

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662375314P 2016-08-15 2016-08-15
US62/375,314 2016-08-15
KR1020237017707A KR102738219B1 (ko) 2016-08-15 2017-08-14 Aav의 검출 방법
PCT/US2017/046814 WO2018035059A1 (en) 2016-08-15 2017-08-14 Methods for detecting aav

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020237017707A Division KR102738219B1 (ko) 2016-08-15 2017-08-14 Aav의 검출 방법

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020267003039A Division KR20260036296A (ko) 2016-08-15 2017-08-14 Aav의 검출 방법

Publications (2)

Publication Number Publication Date
KR20240172773A KR20240172773A (ko) 2024-12-10
KR102922101B1 true KR102922101B1 (ko) 2026-02-03

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ID=59762045

Family Applications (5)

Application Number Title Priority Date Filing Date
KR1020247039853A Active KR102922101B1 (ko) 2016-08-15 2017-08-14 Aav의 검출 방법
KR1020227025409A Active KR102538037B1 (ko) 2016-08-15 2017-08-14 Aav의 검출 방법
KR1020267003039A Pending KR20260036296A (ko) 2016-08-15 2017-08-14 Aav의 검출 방법
KR1020197007381A Active KR102425289B1 (ko) 2016-08-15 2017-08-14 Aav의 검출 방법
KR1020237017707A Active KR102738219B1 (ko) 2016-08-15 2017-08-14 Aav의 검출 방법

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Application Number Title Priority Date Filing Date
KR1020227025409A Active KR102538037B1 (ko) 2016-08-15 2017-08-14 Aav의 검출 방법
KR1020267003039A Pending KR20260036296A (ko) 2016-08-15 2017-08-14 Aav의 검출 방법
KR1020197007381A Active KR102425289B1 (ko) 2016-08-15 2017-08-14 Aav의 검출 방법
KR1020237017707A Active KR102738219B1 (ko) 2016-08-15 2017-08-14 Aav의 검출 방법

Country Status (23)

Country Link
US (5) US11698377B2 (enExample)
EP (2) EP3497207B1 (enExample)
JP (3) JP7021191B2 (enExample)
KR (5) KR102922101B1 (enExample)
CN (2) CN110168080B (enExample)
AU (2) AU2017312951B2 (enExample)
CA (1) CA3033856A1 (enExample)
CL (2) CL2019000392A1 (enExample)
CR (1) CR20190127A (enExample)
CY (1) CY1124364T1 (enExample)
DK (1) DK3497207T3 (enExample)
ES (1) ES2863674T3 (enExample)
HU (1) HUE053747T2 (enExample)
IL (3) IL264819B2 (enExample)
MA (1) MA55748A (enExample)
MX (2) MX2019001938A (enExample)
NZ (3) NZ751711A (enExample)
PH (1) PH12019500316A1 (enExample)
SG (2) SG10201913002QA (enExample)
TN (1) TN2019000047A1 (enExample)
TW (2) TW202309068A (enExample)
WO (1) WO2018035059A1 (enExample)
ZA (2) ZA201900945B (enExample)

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CN111517359B (zh) * 2020-04-23 2021-08-20 江南大学 一种手性硫化铜超粒子的合成方法
RU2748540C1 (ru) * 2021-02-08 2021-05-26 Автономная некоммерческая образовательная организация высшего образования "Сколковский институт науки и технологий" Способ детектирования вируса SARS-CoV-2 методом масс-спектрометрии
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TW202321691A (zh) * 2021-07-12 2023-06-01 美商再生元醫藥公司 用於分析病毒粒子之線上原生質譜方法
CN113552349B (zh) * 2021-07-30 2022-07-19 上海勉亦生物科技有限公司 Aav蛋白外壳的检测方法
JPWO2023132338A1 (enExample) * 2022-01-06 2023-07-13
US20250110119A1 (en) * 2023-03-03 2025-04-03 Sartorius Bioanalytical Instruments, Inc. Methods for quantitating viral capsids
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