KR102840652B1 - 부계 ube3a 발현을 유도하기 위한 올리고뉴클레오티드 - Google Patents
부계 ube3a 발현을 유도하기 위한 올리고뉴클레오티드Info
- Publication number
- KR102840652B1 KR102840652B1 KR1020227045154A KR20227045154A KR102840652B1 KR 102840652 B1 KR102840652 B1 KR 102840652B1 KR 1020227045154 A KR1020227045154 A KR 1020227045154A KR 20227045154 A KR20227045154 A KR 20227045154A KR 102840652 B1 KR102840652 B1 KR 102840652B1
- Authority
- KR
- South Korea
- Prior art keywords
- oligonucleotide
- nucleic acid
- rna
- delete delete
- region
- Prior art date
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| KR1020207033999A KR102482440B1 (ko) | 2015-11-12 | 2016-11-11 | 부계 ube3a 발현을 유도하기 위한 올리고뉴클레오티드 |
| PCT/EP2016/077383 WO2017081223A1 (en) | 2015-11-12 | 2016-11-11 | Oligonucleotides for inducing paternal ube3a expression |
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| JP5868324B2 (ja) | 2010-09-24 | 2016-02-24 | 株式会社Wave Life Sciences Japan | 不斉補助基 |
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| ES2809199T3 (es) | 2012-06-25 | 2021-03-03 | Ionis Pharmaceuticals Inc | Modulación de la expresión de UBE3A-ATS |
| SG11201500239VA (en) | 2012-07-13 | 2015-03-30 | Wave Life Sciences Japan | Asymmetric auxiliary group |
| JP6453212B2 (ja) | 2012-07-13 | 2019-01-16 | ウェイブ ライフ サイエンシズ リミテッドWave Life Sciences Ltd. | キラル制御 |
| WO2015108047A1 (ja) | 2014-01-15 | 2015-07-23 | 株式会社新日本科学 | 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤 |
| WO2015108048A1 (ja) | 2014-01-15 | 2015-07-23 | 株式会社新日本科学 | 抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤 |
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| WO2016086104A1 (en) | 2014-11-25 | 2016-06-02 | Ionis Pharmaceuticals, Inc. | Modulation of ube3a-ats expression |
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| CN108795935B (zh) * | 2018-05-23 | 2022-06-21 | 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) | 日本血吸虫SjELAV-like 1基因的siRNA及其应用 |
| CA3113648A1 (en) | 2018-09-21 | 2020-03-26 | University Of Connecticut | Compositions and methods to restore paternal ube3a gene expression in human angelman syndrome |
| JP7241185B2 (ja) * | 2019-01-17 | 2023-03-16 | エフ. ホフマン-ラ ロシュ アーゲー | E3ユビキチンリガーゼ(ube3a)のタンパク質標的 |
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| JP7701879B2 (ja) | 2019-05-28 | 2025-07-02 | エフ. ホフマン-ラ ロシュ アーゲー | 単球前駆細胞を生成するための方法 |
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2016
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- 2016-11-11 WO PCT/EP2016/077383 patent/WO2017081223A1/en not_active Ceased
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|---|---|---|---|---|
| WO2014004572A2 (en) * | 2012-06-25 | 2014-01-03 | Isis Pharmaceuticals, Inc. | Modulation of ube3a-ats expression |
| US20150191723A1 (en) | 2012-06-25 | 2015-07-09 | Baylor College Of Medicine | Modulation of ube3a-ats expression |
| JP2015529635A (ja) | 2012-06-25 | 2015-10-08 | アイシス ファーマシューティカルズ, インコーポレーテッド | Ube3a−ats発現の調節 |
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