KR102709804B1 - 레티노이드-관련 희귀 수용체 감마(RORγ)의 조절제로서 벤즈이미다졸 유도체 및 이의 약학적 용도 - Google Patents

레티노이드-관련 희귀 수용체 감마(RORγ)의 조절제로서 벤즈이미다졸 유도체 및 이의 약학적 용도 Download PDF

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KR102709804B1
KR102709804B1 KR1020207032236A KR20207032236A KR102709804B1 KR 102709804 B1 KR102709804 B1 KR 102709804B1 KR 1020207032236 A KR1020207032236 A KR 1020207032236A KR 20207032236 A KR20207032236 A KR 20207032236A KR 102709804 B1 KR102709804 B1 KR 102709804B1
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phenyl
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alkyl
benzo
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KR20210005880A (ko
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인파 얀
민셩 장
동 리우
펑치 장
수싱 리우
루민 장
펑 히
웨이캉 타오
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지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드
샹하이 헨그루이 파마수티컬 컴퍼니 리미티드
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KR1020207032236A 2018-05-03 2019-05-03 레티노이드-관련 희귀 수용체 감마(RORγ)의 조절제로서 벤즈이미다졸 유도체 및 이의 약학적 용도 Active KR102709804B1 (ko)

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Application Number Priority Date Filing Date Title
US201862666312P 2018-05-03 2018-05-03
US62/666,312 2018-05-03
PCT/US2019/030526 WO2019213470A1 (en) 2018-05-03 2019-05-03 Benzimidazole derivatives as modulators of retinoid-related orphan receptor gamma (rorϒ) and pharmaceutical uses thereof

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KR102709804B1 true KR102709804B1 (ko) 2024-09-25

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US (2) US11512055B2 (https=)
EP (1) EP3781161B1 (https=)
JP (1) JP7351851B2 (https=)
KR (1) KR102709804B1 (https=)
CN (2) CN116514722A (https=)
AU (1) AU2019262169B2 (https=)
BR (1) BR112020021967A2 (https=)
CA (1) CA3097519A1 (https=)
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MY208400A (en) * 2018-05-03 2025-05-07 Shanghai hengrui pharmaceutical co ltd Benzimidazole derivatives as modulators of retinoid-related orphan receptor gamma (ror) and pharmaceutical uses thereof
US20220411380A1 (en) * 2019-10-31 2022-12-29 Jiangsu Hengrui Medicine Co., Ltd. ACID ADDITION SALT OF RORy REGULATOR
CN112745268B (zh) * 2019-10-31 2022-09-16 江苏恒瑞医药股份有限公司 苯并咪唑衍生物的晶型及制备方法
TW202136238A (zh) * 2020-01-06 2021-10-01 大陸商廣東東陽光藥業有限公司 RORγt抑制劑及其製備方法和用途
TW202136237A (zh) * 2020-01-06 2021-10-01 大陸商廣東東陽光藥業有限公司 RORγt抑制劑及其製備方法和用途
CN111269126B (zh) * 2020-03-12 2023-04-07 北京理工大学重庆创新中心 一种熔铸载体1,2-二氟-4,5-二硝基苯的制备方法
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