KR102685211B1 - 항-c-Met 항체 또는 그의 항원 결합 단편을 포함하는 키메라 항원 수용체, 및 이의 용도 - Google Patents

항-c-Met 항체 또는 그의 항원 결합 단편을 포함하는 키메라 항원 수용체, 및 이의 용도 Download PDF

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KR102685211B1
KR102685211B1 KR1020190119148A KR20190119148A KR102685211B1 KR 102685211 B1 KR102685211 B1 KR 102685211B1 KR 1020190119148 A KR1020190119148 A KR 1020190119148A KR 20190119148 A KR20190119148 A KR 20190119148A KR 102685211 B1 KR102685211 B1 KR 102685211B1
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met
ser
sequence
gly
cells
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채진아
유승신
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주식회사 헬릭스미스
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Priority to KR1020190119148A priority Critical patent/KR102685211B1/ko
Priority to CN202080067658.8A priority patent/CN114450407A/zh
Priority to PCT/KR2020/013127 priority patent/WO2021060932A1/ko
Priority to US17/763,712 priority patent/US12570719B2/en
Priority to JP2022519423A priority patent/JP7373242B2/ja
Priority to EP20868836.6A priority patent/EP4039703A4/en
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
    • A—HUMAN NECESSITIES
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/4203—Receptors for growth factors
    • A61K40/4209—Hepatocyte growth factor receptor [HGFR] or c-met]
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    • C07K14/70514—CD4
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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KR1020190119148A 2019-09-26 2019-09-26 항-c-Met 항체 또는 그의 항원 결합 단편을 포함하는 키메라 항원 수용체, 및 이의 용도 Active KR102685211B1 (ko)

Priority Applications (6)

Application Number Priority Date Filing Date Title
KR1020190119148A KR102685211B1 (ko) 2019-09-26 2019-09-26 항-c-Met 항체 또는 그의 항원 결합 단편을 포함하는 키메라 항원 수용체, 및 이의 용도
CN202080067658.8A CN114450407A (zh) 2019-09-26 2020-09-25 包含抗-间质表皮转化因子抗体或其抗原结合片段的嵌合抗原受体及其用途
PCT/KR2020/013127 WO2021060932A1 (ko) 2019-09-26 2020-09-25 항-c-met 항체 또는 그의 항원 결합 단편을 포함하는 키메라 항원 수용체, 및 이의 용도
US17/763,712 US12570719B2 (en) 2019-09-26 2020-09-25 Chimeric antigen receptor comprising anti c-met antibody or antigen binding fragment thereof, and use thereof
JP2022519423A JP7373242B2 (ja) 2019-09-26 2020-09-25 抗ｃ－ｍｅｔ抗体又はその抗原結合断片を含むキメラ抗原受容体、及びその用途
EP20868836.6A EP4039703A4 (en) 2019-09-26 2020-09-25 Chimeric antigen receptor comprising anti c-met antibody or antigen binding fragment thereof, and use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020190119148A KR102685211B1 (ko) 2019-09-26 2019-09-26 항-c-Met 항체 또는 그의 항원 결합 단편을 포함하는 키메라 항원 수용체, 및 이의 용도

Publications (2)

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KR20210036742A KR20210036742A (ko) 2021-04-05
KR102685211B1 true KR102685211B1 (ko) 2024-07-16

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KR1020190119148A Active KR102685211B1 (ko) 2019-09-26 2019-09-26 항-c-Met 항체 또는 그의 항원 결합 단편을 포함하는 키메라 항원 수용체, 및 이의 용도

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Country Link
US (1) US12570719B2 (https=)
EP (1) EP4039703A4 (https=)
JP (1) JP7373242B2 (https=)
KR (1) KR102685211B1 (https=)
CN (1) CN114450407A (https=)
WO (1) WO2021060932A1 (https=)

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PH12013501201A1 (en) * 2010-12-09 2013-07-29 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
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KR101615619B1 (ko) 2014-08-07 2016-04-26 주식회사 파멥신 c-Met 특이적 인간 항체 및 그 제조방법
CN109153975A (zh) * 2015-12-28 2019-01-04 诺华股份有限公司 制备嵌合抗原受体表达细胞的方法
KR102476846B1 (ko) * 2016-02-05 2022-12-12 주식회사 헬릭스미스 항―ｃ―ＭＥＴ 항체 및 이의 용도
CN106008721B (zh) * 2016-08-09 2020-02-07 安徽未名细胞治疗有限公司 一种c-Met特异性嵌合抗原受体及其应用
US20180257300A1 (en) 2017-03-09 2018-09-13 Applied Materials, Inc. Additive manufacturing with energy delivery system having rotating polygon and adjustment of angle of light path
CN109422815A (zh) 2017-08-28 2019-03-05 复旦大学 双特异性嵌合抗原受体c-Met/PD-1 scFv-CAR-T及其构建方法和应用
CN108341881B (zh) 2018-01-31 2020-08-18 深圳市默赛尔生物医学科技发展有限公司 带安全开关的嵌合抗原受体及其表达基因、其修饰的nk细胞及应用
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WO2021060932A1 (ko) 2021-04-01
EP4039703A1 (en) 2022-08-10
EP4039703A4 (en) 2023-07-19
CN114450407A (zh) 2022-05-06
KR20210036742A (ko) 2021-04-05
US12570719B2 (en) 2026-03-10
JP7373242B2 (ja) 2023-11-02
JP2022550120A (ja) 2022-11-30
US20220362298A1 (en) 2022-11-17

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