KR102647794B1 - 암을 치료하기 위한 액체 투여형 - Google Patents
암을 치료하기 위한 액체 투여형 Download PDFInfo
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- KR102647794B1 KR102647794B1 KR1020207000409A KR20207000409A KR102647794B1 KR 102647794 B1 KR102647794 B1 KR 102647794B1 KR 1020207000409 A KR1020207000409 A KR 1020207000409A KR 20207000409 A KR20207000409 A KR 20207000409A KR 102647794 B1 KR102647794 B1 KR 102647794B1
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A—HUMAN NECESSITIES
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- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
Landscapes
- Health & Medical Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
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- General Chemical & Material Sciences (AREA)
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- Physiology (AREA)
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| US62/520,768 | 2017-06-16 | ||
| PCT/US2018/036703 WO2018227119A1 (en) | 2017-06-09 | 2018-06-08 | Liquid dosage forms to treat cancer |
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| KR20200014903A KR20200014903A (ko) | 2020-02-11 |
| KR102647794B1 true KR102647794B1 (ko) | 2024-03-15 |
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| JP2014505109A (ja) * | 2011-02-10 | 2014-02-27 | エクセリクシス， インク． | キノリン化合物およびそのような化合物を含有する医薬組成物の調製方法 |
| EP3634413A1 (en) | 2017-06-09 | 2020-04-15 | Exelixis, Inc. | Liquid dosage forms to treat cancer |
| UA128476C2 (uk) | 2018-01-26 | 2024-07-24 | Екселіксіс, Інк. | Сполуки для лікування кіназозалежних розладів |
| CN113292537B (zh) | 2018-06-15 | 2024-04-05 | 汉达癌症医药责任有限公司 | 激酶抑制剂的盐类及其组合物 |
| TW202444365A (zh) | 2023-01-31 | 2024-11-16 | 漢達生技醫藥股份有限公司 | 改良之卡博替尼組合物及其使用方法 |
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| US6136846A (en) | 1999-10-25 | 2000-10-24 | Supergen, Inc. | Formulation for paclitaxel |
| PT2213661E (pt) | 2003-09-26 | 2011-12-15 | Exelixis Inc | Moduladores de c-met e métodos de uso |
| US7989490B2 (en) | 2004-06-02 | 2011-08-02 | Cordis Corporation | Injectable formulations of taxanes for cad treatment |
| WO2008083319A1 (en) | 2006-12-29 | 2008-07-10 | Il Yang Pharmaceutical Company, Ltd. | Solid state forms of enantiopure ilaprazole |
| SG173014A1 (en) * | 2009-01-16 | 2011-08-29 | Exelixis Inc | Malate salt of n- (4- { [ 6, 7-bis (methyloxy) quin0lin-4-yl] oxy}phenyl)-n' - (4 -fluorophenyl) cyclopropane-1,1-dicarboxamide, and crystalline forms therof for the treatment of cancer |
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| UA111342C2 (uk) | 2010-10-29 | 2016-04-25 | Троікаа Фармасьютікалс Лімітед | Назальні композиції вітаміну b12 |
| KR20140025496A (ko) | 2011-05-02 | 2014-03-04 | 엑셀리시스, 인코포레이티드 | 암 및 뼈 암 통증의 치료방법 |
| GEP201606523B (en) * | 2011-09-22 | 2016-08-10 | Exelixis Inc | Method for treating osteoporosis |
| ITRM20120331A1 (it) | 2012-07-12 | 2014-01-13 | Guidotti & C Spa Labor | Composizioni pediatriche orali liquide contenenti nepadutant. |
| BR112015001838B1 (pt) | 2012-07-27 | 2022-10-25 | Izumi Technology, Llc | Composição de inibidor de efluxo |
| KR102354963B1 (ko) | 2014-02-14 | 2022-01-21 | 엑셀리시스, 인코포레이티드 | N-｛4-[(6,7-다이메톡시퀴놀린-4-일)옥시]페닐｝-n'-(4-플루오로페닐) 사이클로프로판-1,1-다이카복스아마이드의 결정질 고체 형태, 제조 방법 및 사용 방법 |
| IL248408B (en) | 2014-04-25 | 2022-06-01 | Exelixis Inc | A method for treating adenocarcinoma of the lungs |
| ES2929888T3 (es) * | 2014-07-31 | 2022-12-02 | Exelixis Inc | Procedimiento para preparar cabozantinib marcado con flúor 18 y sus análogos |
| EP3634413A1 (en) | 2017-06-09 | 2020-04-15 | Exelixis, Inc. | Liquid dosage forms to treat cancer |
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| WO2018227119A1 (en) | 2018-12-13 |
| AU2018279834B2 (en) | 2024-05-23 |
| KR20200014903A (ko) | 2020-02-11 |
| JP7249962B2 (ja) | 2023-03-31 |
| CN110678180A (zh) | 2020-01-10 |
| UA126402C2 (uk) | 2022-09-28 |
| JP2020523317A (ja) | 2020-08-06 |
| US12016854B2 (en) | 2024-06-25 |
| US20200268737A1 (en) | 2020-08-27 |
| AU2018279834A1 (en) | 2020-01-16 |
| MX2019014298A (es) | 2020-02-03 |
| CA3065560A1 (en) | 2018-12-13 |
| US20230301978A1 (en) | 2023-09-28 |
| US11504362B2 (en) | 2022-11-22 |
| BR112019025110A2 (pt) | 2020-09-01 |
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