KR102591508B1 - Anti-bacterial composition and cosmetic composition for improving of dandruff or acne comprising the same - Google Patents

Abstract

The present invention relates to an antibacterial composition and a cosmetic composition containing the same for improving dandruff or acne. The present invention relates to an antibacterial composition and a cosmetic composition containing the same for improving dandruff or acne. The antibacterial effect is increased compared to the use of only the wood extract, including wood grain extract, Schisandra chinensis extract, and chitosan, and in particular, the dandruff bacteria (Malassezia purpur). It has an excellent antibacterial effect against Malassezia furfur and Cutibacterium acnes , making it excellent for improving dandruff or acne.

Description

Antibacterial composition and cosmetic composition for improving dandruff or acne comprising the same {Anti-bacterial composition and cosmetic composition for improving of dandruff or acne comprising the same}

The present invention relates to an antibacterial composition and a cosmetic composition containing the same for improving dandruff or acne.

The scalp has sweat glands and sebaceous glands widely distributed, making it a good environment for microorganisms to proliferate, and many microorganisms reside there. The main resident microorganisms are divided into three groups: anaerobic bacteria, aerobic cocci, and the fungus Malassezia species. Dandruff occurs when Malassezia bacteria, one of these scalp-resident bacteria, begins to exist in seborrheic areas such as the scalp after puberty when male hormones are secreted. In particular, dandruff bacteria proliferate excessively due to environmental factors such as climate, sweat, food, and physiological factors such as stress, causing dandruff when the total number of normal bacteria exceeds 74%, and seborrheic dermatitis occurs when the number exceeds 83%. In this way, dandruff is a metabolic by-product that occurs naturally in living skin cells, a mixture of aging flakes of the scalp falling off in the shape of rice bran and decomposed oxides of sebum. It can be said to be a mild form of seborrheic dermatitis. However, when these symptoms become severe, it is called dandruff, clinically it is called pityriasis on the head, and medically it is called dry seborrhea. Severe pain, itchiness, inflammation, or erythema on the scalp are symptoms caused by dandruff bacteria, and for treatment, the growth of dandruff bacteria must be suppressed.

Meanwhile, acne is an inflammatory disease that occurs in the hair follicles and pores of the skin and is mainly caused by increased secretion of sex hormones during puberty. In particular, androgen, a male hormone, stimulates the sebaceous glands to increase sebum secretion, and when acne bacteria invade the skin, free unsaturated fatty acids are produced through lipolysis by lipase, causing acne to form in hair follicles and around them. (Ki Ho-gyun et al., Journal of Korean Dermatology, 43:871-875, 2005). If acne is left untreated, purulence may form on the face, leaving scars, and pores may become enlarged, making the skin look like a tangerine peel. Therefore, appropriate treatment is required because acne can leave a psychological scar on teenagers and adults who are sensitive to their appearance.

Accordingly, in Korea, natural products are attracting attention as alternative medicines for treating dandruff or acne by reducing side effects and improving treatment effects. This is because therapeutic agents using natural extracts that have been used since ancient times and have been proven to be harmless to the human body can overcome resistance or safety issues caused by existing therapeutic agents. Therefore, research is needed on natural products that have excellent antibacterial effects against dandruff and acne bacteria.

Korean Patent No. 1496926

The purpose of the present invention is to provide an antibacterial composition.

The purpose of the present invention is to provide a cosmetic composition for improving dandruff.

The purpose of the present invention is to provide a cosmetic composition for improving acne.

1. An antibacterial composition containing Cattlewood extract, Schisandra chinensis extract, and chitosan.

2. The antibacterial composition according to item 1 above, wherein the wood extract is a hot water extract.

3. The antibacterial composition according to 1 above, wherein the Somatophyll extract, Schisandra chinensis extract, and chitosan are contained in a weight ratio of 1:0.125:0.025 to 1.

4. The antibacterial composition according to 1 above, wherein the composition contains 0.01 to 0.5% by weight of the Sophyllum extract.

5. The antibacterial composition of 1 above, wherein the composition contains 0.01 to 0.25% by weight of the Schisandra chinensis extract.

6. The antibacterial composition of 1 above, wherein the composition contains 0.005 to 0.25% by weight of chitosan.

7. The method of 1 above, wherein the bacteria are Escherichia coli , Staphylococcus aureus , Cutibacterium acnes , or Malassezia furfur . , antibacterial composition.

8. A cosmetic composition for improving dandruff containing the composition of any one of items 1 to 7 above.

9. A cosmetic composition for improving acne comprising the composition of any one of items 1 to 7 above.

The present invention relates to an antibacterial composition and a cosmetic composition containing the same for improving dandruff or acne. The present invention relates to an antibacterial composition and a cosmetic composition containing the same for improving dandruff or acne. The antibacterial effect is increased compared to the use of only the wood extract, including wood grain extract, Schisandra chinensis extract, and chitosan, and in particular, the dandruff bacteria (Malassezia purpur). It has an excellent antibacterial effect against Malassezia furfur and Cutibacterium acnes , making it excellent for improving dandruff or acne.

Figure 1 shows the measurement of antibacterial activity of Somatophyll extract using disk diffusion method.
Figures 2 to 5 show the measurement of the bacterial growth inhibitory activity of the Cattlewood extract over time (Figure 2 for E. coli , Figure 3 for S. aureus , Figure 4 for C. acnes , and Figure 5 for M. furfur ).
Figures 6 to 9 are measurements of the bacterial growth inhibitory activity of the mixed solution of Cattlewood extract and chitosan over time (Figure 6 is E. coli , Figure 7 is S. aureus , Figure 8 is C. acnes , Figure 9 is M . furfur ).

Hereinafter, the present invention will be described in detail.

The present invention provides an antibacterial composition.

The composition of the present invention includes Cattle sinensis extract, Schisandra chinensis extract, and chitosan.

The wood extract may be a hot water extract, cold soak extract, reflux extract, solvent extract, steam distillation extract, ultrasonic extract, eluate, or pressed extract. However, in terms of containing an appropriate amount of the active ingredients in wood wood to exert antibacterial efficacy, hot water extract is specifically used. It may be an extract.

For example, the Cattle extract, Schisandra chinensis extract and chitosan may be included in a weight ratio of 1:0.125:0.02 to 1, 1:0.125:0.05 to 0.8, or 1:0.125:0.1 to 0.6. It is not limited to the above range, but when included within the above range, the Cattlewood extract can exhibit excellent antibacterial effects.

The composition of the present invention may include 0.01 to 0.5% by weight, 0.03 to 0.1% by weight, or 0.05 to 0.08% by weight of the Somatophyll extract. It is not limited thereto, but when included within the above range, the antibacterial effect of the Cattlewood extract is excellent, and is particularly suitable for the antibacterial effect against dandruff and acne bacteria.

The composition of the present invention may include 0.01 to 0.25% by weight, 0.03 to 0.1% by weight, or 0.05 to 0.08% by weight of the Schisandra chinensis extract. It is not limited thereto, but when included within the above range, the antibacterial effect of the Cattlewood extract is excellent, and is particularly suitable for the antibacterial effect against dandruff and acne bacteria.

The composition of the present invention may include 0.005 to 0.25% by weight, 0.007 to 0.1% by weight, or 0.01 to 0.05% by weight of chitosan. Although it is not limited thereto, chitosan can maximize the antibacterial activity of the Cattlewood extract even when included within the above range, so it is preferable not to include more than that.

The composition of the present invention is effective against, for example, Escherichia coli , Staphylococcus aureus , Cutibacterium acnes or Malassezia furfur . This may indicate an antibacterial effect. Specifically, it has an excellent antibacterial effect against Cutibacteria acnes or Malassezia furfur, and is excellent for improving acne or dandruff.

The composition of the present invention may further include carbohydrates, proteins, lipids, vitamins and minerals in addition to the above active ingredients. The sugar may be appropriately selected depending on its purpose and purpose, and examples include honey, dextrin, sucrose, palatinose, glucose, fructose, starch syrup, sugar alcohol, sorbitol, xylitol, and maltitol. It is not particularly limited thereto. The protein may be appropriately selected depending on the purpose and purpose of its use. For example, milk-derived proteins such as casein and whey protein, soy proteins, and animal-derived enzymes such as trypsin and pepsin of these proteins. and a hydrolyzate by neutrase or alkalase, but is not particularly limited thereto. The lipid may be appropriately selected depending on the purpose and purpose of use. For example, sunflower oil containing monovalent saturated fatty acids and polyunsaturated fatty acids, rapeseed oil, olive oil, safflower oil, and corn oil. , various plant-derived fats and oils such as soybean oil, palm oil, and palm oil, middle-chain fatty acids, EPA, DHA, soybean-derived phospholipids, and milk-derived phospholipids, but are not particularly limited thereto. There are no particular restrictions on the vitamins, and the minerals may be appropriately selected depending on the purpose and purpose of use. Examples include potassium phosphate, potassium carbonate, potassium chloride, sodium chloride, calcium lactate, calcium gluconate, calcium pantothenate, and calcium caseinate. , magnesium chloride, ferrous sulfate, and sodium bicarbonate, but are not particularly limited thereto. Any of the carbohydrates, proteins, lipids, vitamins and minerals are not limited to the above specific examples and may include other ingredients as long as the antibacterial properties of the composition are maintained, and the content of each is not limited as long as the antibacterial properties are maintained. , preferably 0.1 to 15% by weight, preferably 0.5 to 10% by weight, relative to the total composition.

The present invention provides a cosmetic composition for improving dandruff containing the above composition.

The cosmetic composition of the present invention has an excellent antibacterial effect against Malassezia furfur due to the wood extract, Schisandra chinensis extract, and chitosan, and thus has an excellent dandruff improvement effect.

The cosmetic composition of the present invention may contain ingredients commonly used in cosmetic compositions in addition to the above ingredients as active ingredients, and includes, for example, conventional auxiliaries and carriers such as stabilizers, solubilizers, vitamins, pigments, and fragrances. can do.

The cosmetic composition of the present invention can be prepared in any formulation commonly manufactured in the art, and when the formulation of the present invention is a paste, cream, or gel, animal fiber, vegetable fiber, wax, paraffin, starch, and trimethylamine are used as carrier ingredients. Kant, cellulose derivatives, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide can be used. When the formulation of the present invention is a powder or spray, lactose, talc, silica, aluminum hydroxide, calcium silicate, or polyamide powder can be used as the carrier ingredient. In particular, when the formulation is a spray, chlorofluorohydrocarbon and propane may be used as carrier ingredients. /May contain propellants such as butane or dimethyl ether. When the formulation of the present invention is a solution or emulsion, a solvent, solvating agent, or emulsifying agent is used as a carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1 , 3-butyl glycol oil, glycerol aliphatic esters, polyethylene glycol or fatty acid esters of sorbitan. When the formulation of the present invention is a suspension, the carrier ingredients include water, liquid diluents such as ethanol or propylene glycol, suspending agents such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, and microcrystals. Cellulose, aluminum metahydroxide, bentonite, agar, or tracant may be used. When the formulation of the present invention is a surfactant-containing cleansing agent, the carrier ingredients include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyl taurate, sarcosinate, and fatty acid amide. Ether sulfate, alkylamidobetaine, fatty alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, linoline derivative, or ethoxylated glycerol fatty acid ester can be used.

The cosmetic composition of the present invention can be applied in the form of various products, for example, hair cosmetics, emulsions, creams, lotions, packs, foundations, lotions, serums, etc. In order to improve dandruff, it is preferable to manufacture hair cosmetic products. Examples of hair product applications include pre-shampoo compositions, shampoos, rinses, treatments, waxes, sprays, mousses, hair lotions, essences, and hair products. It can include creams, permanent hair dyes, temporary hair dyes, perms, non-woven fabrics, sheets, etc.

The present invention provides a cosmetic composition for improving acne comprising the above composition.

The cosmetic composition of the present invention has an excellent antibacterial effect against Cutibacterium acnes due to Somatophyll extract, Schisandra chinensis extract, and chitosan, and thus has an excellent acne improvement effect.

The cosmetic composition of the present invention may contain ingredients commonly used in cosmetic compositions in addition to the above ingredients as active ingredients, and includes, for example, conventional auxiliaries and carriers such as stabilizers, solubilizers, vitamins, pigments, and fragrances. can do.

The cosmetic composition of the present invention can be manufactured in any formulation commonly manufactured in the art, and examples include emulsion, cream, lotion, pack, foundation, lotion, beauty essence, hair cosmetics, etc. Specifically, the cosmetic composition of the present invention includes skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutritional lotion, massage cream, nutritional cream, moisture cream, hand cream, foundation, essence, nutritional essence, It may include formulations of packs, soaps, cleansing foams, cleansing lotions, cleansing creams, body lotions, and body cleansers. When the formulation of the present invention is a paste, cream or gel, animal fiber, plant fiber, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide may be used as the carrier ingredient. You can. When the formulation of the present invention is a powder or spray, lactose, talc, silica, aluminum hydroxide, calcium silicate, or polyamide powder can be used as the carrier ingredient. In particular, when the formulation is a spray, chlorofluorohydrocarbon and propane may be used as carrier ingredients. /May contain propellants such as butane or dimethyl ether. When the formulation of the present invention is a solution or emulsion, a solvent, solvating agent, or emulsifying agent is used as a carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1 , 3-butyl glycol oil, glycerol aliphatic esters, polyethylene glycol or fatty acid esters of sorbitan. When the formulation of the present invention is a suspension, the carrier ingredients include water, liquid diluents such as ethanol or propylene glycol, suspending agents such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, and microcrystals. Cellulose, aluminum metahydroxide, bentonite, agar, or tracant may be used. When the formulation of the present invention is a surfactant-containing cleansing agent, the carrier ingredients include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyl taurate, sarcosinate, and fatty acid amide. Ether sulfate, alkylamidobetaine, fatty alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, linoline derivative, or ethoxylated glycerol fatty acid ester can be used.

Hereinafter, the present invention will be described in detail with reference to examples.

Ingredients Preparation

1. Preparation of Cattlewood extract

To prepare the Somok hot water extract, 10 g of Somok powder was immersed in 100 ml of tertiary distilled water and then subjected to hot water extraction at 121°C for 15 minutes using a high-temperature and high-pressure steam sterilizer (ES-315, TOMY, Nerima-ku, Tokyo, Japan). Afterwards, it was cooled at room temperature for 3 hours. Afterwards, the primary extract of Somatophyta was centrifuged at 4,000 rpm for 10 minutes, and the supernatant was stored at room temperature and used in the experiment.

2. Preparation of Schisandra chinensis extract

To prepare Schisandra chinensis extract, 100 mL of 70% ethanol was added to 20 g of dried Schisandra chinensis, extracted at room temperature for 24 hours, and then the same amount of solvent was added again and extracted with shaking at 60°C for 4 hours. The extract is Whatman No. 1 After filtering with filter paper and concentrating with a vacuum concentrator (Eyela, Tokyo Rikakikai Co., Tokyo, Japan), it was prepared to a concentration of 5 brix.

3. Strains and media

Three types of bacteria and one type of fungus were used as microorganisms to confirm antibacterial activity. Escherichia coli was isolated and identified from commercially available pork and confirmed to be E. coli. Staphylococcus aureus ATCC 29213 was used as a strain distributed from the Korea Microbiological Conservation Center, and Cutibacterium acnes ATCC 6919 was used as a strain purchased from the Korea Biological Resources Center. The fungus Malassezia furfur ATCC 14521 was purchased from the Korea Biological Resources Center and used. For bacterial culture, Luria-Bertani broth and Luria-Bertani agar (LB agar, BD biosciences, Franklin Lakes, NJ, USA), Tryptics soy broth and Tryptics soy agar (LB agar, BD biosciences, Franklin Lakes, NJ, USA) were used. Yeast mold broth and yeast mold agar (YM agar, BD biosciences, Franklin Lakes, NJ, USA) were used for fungal culture.

Experimental methods and results

1. Measurement of Minimum Growth Inhibitory Concentration (MIC) for strains of Cattlewood extract

To measure the minimum growth inhibitory concentration (MIC) of the woody extract for the test strain, dilute 5% of the hotwater extract of the woody wood in sterilized TSB broth until the minimum concentration is 0.005% and add 100 ㎕ to a 96 well plate. After adding each strain, 100 ㎕ of 1 By measuring the absorbance at a wavelength of 595 nm, the concentration of the Somok hydrothermal extract at which the inoculated strain did not grow was taken as the MIC.

The results are shown in Table 1, and the minimum inhibitory concentration for the experimental strains of the hot water extract of Somatophyta sinensis was 0.16% for E. coli , 0.312% for S. aureus , 0.312% for C. acnes , and M. furfur . It was found to be 0.08%.

Bacterial strain MIC concentration (%) C.sappan Extract E. coli 0.16 S. aureus 0.312 C. acnes 0.312 M. furfur 0.08

2. Measurement of antibacterial activity of Somatophyllum hydrothermal extract using disk diffusion method

The antibacterial activity of the hot water extract of Somatophyta was confirmed by disk diffusion method. A sterilized 8mm paper disc was prepared by inoculating 80 ㎕ of each concentration of Solanum hot water extract. For strain inoculation, the culture was transplanted into 3 ml of culture medium sterilized through a high-temperature and high-pressure sterilizer and cultured with shaking at 37°C for 24 hours. The cultured strain was diluted to 1 was confirmed by repeated measurements three times.

For three types of bacteria, E. coli , S. aureus , and C. acnes , and one type of fungus, M. furfur , distilled water as a negative control, 4% 1,2-hexanediol as a positive control, and different concentrations of wood as an experimental group. Hot water extracts (5%, 2.5%, 1.25%, 0.625%, 0.312%) were applied to paper discs, respectively.

The results are shown in Figure 1 and Table 2.

Sample Clear zone size (mm) (susceptibility) E. coli S. aureus C. acnes M. furfur Control 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 1,2-Hexandiol 13.00 ± 0.57 12.00 ± 0.47 11.00 ± 0.57 12.00 ± 0.57 5% C. sappan extract 18.00 ± 0.82 17.66 ± 0.47 17.66 ± 0.47 25.66 ± 0.57 2.5% C. sappan extract 15.34 ± 0.57 15.34 ± 0.57 13.33 ± 0.57 21.66 ± 0.57 1.25% C. sappan extract 12.00 ± 1.00 12.00 ± 1.00 9.34 ± 0.57 15.66 ± 0.57 0.625% C. sappan extract 9.34 ± 0.57 9.00 ± 0.00 8.00 ± 0.00 10.66 ± 0.57 0.3125% C. sappan extract 8.00 ± 0.00 9.00 ± 0.00 8.00 ± 0.00 8.00 ± 0.00

3. Measurement of bacterial growth inhibitory activity of Somok extract over time

The bacterial growth inhibitory effect of Somok hot water extract was measured using the absorbance method. For strain inoculation, the culture was transplanted into 3 ml of culture medium sterilized through a high-temperature and high-pressure sterilizer and cultured with shaking at 37°C for 24 hours. The cultured strain was diluted to a concentration of 1 200 ㎕ of the mixed solution was dispensed into a 96 well plate and cultured at 37°C for 24 hours. Absorbance was measured at 595 nm wavelength at 2-hour intervals to confirm bacterial proliferation tendency. For three types of bacteria, E. coli , S. aureus , and C. acnes , and one type of fungus, M. furfur , distilled water as a negative control, 4% 1,2-hexanediol as a positive control, and different concentrations of wood as an experimental group. Hot water extracts (2.5%, 1.25%, 0.625%, 0.312%, 0.16%, 0.08%, 0.04%, 0.02%, 0.01%, 0.005%) were treated respectively.

The results are shown in Figures 2 to 5. The hydrothermal extract of the pine tree contains more than 0.16% for E. coli (Figure 2), more than 0.312% for S. aureus (Figure 3), more than 0.312% for C. acnes (Figure 4), and 0.08% for M. furfur . From the above (FIG. 5), it was confirmed that it had antibacterial activity.

4. Measurement of minimum growth inhibitory concentration (MIC) for strains of Schisandra chinensis extract

To measure the minimum growth inhibitory concentration (MIC) of the Schisandra chinensis extract for the experimental strain, the Schisandra chinensis extract was sterilized using a 0.45 μm filter (Whatman International, England), and then samples for each concentration were prepared through the serial dilution method. used. After adding 100 ㎕ to a 96 well plate, add 100 ㎕ of each strain at ¹ Waltham, MA, USA), the absorbance was measured at a wavelength of 595 nm, and the concentration of Schisandra chinensis extract at which the inoculated strain did not grow was determined as the MIC.

The results are shown in Table 3, and the minimum inhibitory concentration of Schisandra chinensis extract against the experimental strains was 0.16% for E. coli , 0.312% for S. aureus , 0.312% for C. acnes , and 0.08 for M. furfur. It was expressed as %.

Bacterial strain MIC concentration (%) S. chinensis Extract E. coli 0.457 S. aureus 0.914 C. acnes 0.914 M. furfur 0.914

5. Measurement of Minimum Growth Inhibitory Concentration (MIC) for strains of Cattlewood extract and chitosan mixed solution

In order to measure the minimum growth inhibitory concentration (MIC) of the hot water extract of the quince tree for the experimental strain, 5% of the hot water extract of the quince tree was diluted by 1/2 with sterilized TSB broth until the minimum concentration was 0.005%, and the concentration of chitosan was 0.01%. After adding 100 ㎕ to a 96 well plate, add ¹⁰⁰ ㎕ of each strain at 1 Multickan™ GO, Thermofisher, Waltham, MA, USA) was used to measure the absorbance at a wavelength of 595 nm, and the concentration of the mixed solution of Somatophyta extract and chitosan in which the inoculated strain did not grow was determined as the MIC.

The results are shown in Table 5. As a result, changes in MIC due to Somatophylla hot water extract and MIC due to Somatophyta hot water extract and chitosan were found, with an 8-fold decrease from 0.16% to 0.02% for E. coli and an 8-fold decrease from 0.312% to 0.04% for S. aureus. It was found that there was a decrease from 0.312% to 0.08% for C. acnes and from 0.08% to 0.04% for M. furfur .

Bacterial strain MIC concentration (%) C. sappan Extract containing BioActive-Chitosan E. coli 0.02 S. aureus 0.04 C. acnes 0.08 M. furfur 0.04

6. Measurement of bacterial growth inhibitory activity of Cattlewood extract and chitosan mixed solution over time

The bacterial growth inhibitory effect of Somok hot water extract was measured using the absorbance method. For strain inoculation, the culture was transplanted into 3 ml of culture medium sterilized through a high-temperature and high-pressure sterilizer and cultured with shaking at 37°C for 24 hours. After diluting the cultured strain to a concentration of 1 %, 0.08%, 0.04%, 0.02%, 0.01%, 0.005%) and mixed. 200 ㎕ of the mixed solution was dispensed into a 96 well plate and incubated at 37°C for 24 hours. Absorbance was measured at 595 nm wavelength at 2-hour intervals to confirm bacterial proliferation tendency.

The results are shown in Figures 6 to 9. Changes in the antibacterial activity by the Arboretum hot-water extract and the antibacterial activity by the Arborvitae hot-water extract and chitosan were found, and the Arboretum hot-water extract had an effect of more than 0.02% against E. coli (Figure 6) and more than 0.04% against S. aureus (Figure 6). Figure 7), it was confirmed that there was antibacterial activity against C. acnes at more than 0.08% (Figure 8), and at least 0.04% against M. furfur (Figure 9). It was confirmed that the antibacterial activity of the hot water extract of the pine tree was increased by the addition of chitosan. Could know.

Claims (9)

Contains Somok extract, Schisandra chinensis extract and chitosan,
The antibacterial composition wherein the wood extract is a hot water extract.
delete The antibacterial composition according to claim 1, wherein the Somato extract, Schisandra chinensis extract, and chitosan are included in a weight ratio of 1:0.125:0.025 to 1.
The antibacterial composition according to claim 1, wherein the composition comprises 0.01 to 0.5% by weight of the wood extract.
The antibacterial composition according to claim 1, wherein the composition contains 0.01 to 0.25% by weight of the Schisandra chinensis extract.
The antibacterial composition according to claim 1, wherein the composition contains 0.005 to 0.25% by weight of chitosan.
The method of claim 1, wherein the bacteria are Escherichia coli , Staphylococcus aureus, Cutibacterium acnes , or Malassezia furfur . Composition for.
A cosmetic composition for improving dandruff comprising the composition of any one of claims 1, 3 to 7.
A cosmetic composition for improving acne comprising the composition of any one of claims 1, 3 to 7.