KR102504884B1 - Sftsv에 결합 가능한 나노 항체 및 이의 응용 - Google Patents

Sftsv에 결합 가능한 나노 항체 및 이의 응용 Download PDF

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KR102504884B1
KR102504884B1 KR1020207022152A KR20207022152A KR102504884B1 KR 102504884 B1 KR102504884 B1 KR 102504884B1 KR 1020207022152 A KR1020207022152 A KR 1020207022152A KR 20207022152 A KR20207022152 A KR 20207022152A KR 102504884 B1 KR102504884 B1 KR 102504884B1
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KR20210013000A (ko
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시린 우
즈웨이 우
옌레이 리
이 판
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와이-클론 메디컬 사이언시스 컴퍼니 리미티드
(주) 팬젠
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1020207022152A 2019-07-23 2019-07-23 Sftsv에 결합 가능한 나노 항체 및 이의 응용 KR102504884B1 (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2019/097350 WO2021012195A1 (zh) 2019-07-23 2019-07-23 可结合sftsv的纳米抗体及其应用

Publications (2)

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KR20210013000A KR20210013000A (ko) 2021-02-03
KR102504884B1 true KR102504884B1 (ko) 2023-02-28

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JP (1) JP7171737B2 (ja)
KR (1) KR102504884B1 (ja)
CN (3) CN112105637B (ja)
WO (1) WO2021012195A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112105637B (zh) * 2019-07-23 2022-12-06 源道隆(苏州)医学科技有限公司 可结合sftsv的纳米抗体及其应用
CN112724248A (zh) * 2021-01-28 2021-04-30 南京拓峰生物科技有限公司 可结合SARS-CoV-2的纳米抗体及其应用
CN113980125B (zh) * 2021-10-15 2024-03-26 中国科学院武汉病毒研究所 一种抗sftsv的中和性单克隆抗体及其应用
CN117229413A (zh) * 2023-09-04 2023-12-15 中国人民解放军军事科学院军事医学研究院 一种针对SFTSV-Gn和CD3的双特异性抗体及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009040780A (ja) * 1996-06-27 2009-02-26 Vlaams Interuniversitair Inst Voor Biotechnologie 標的分子の活性部位またはクレフトと特異的に相互作用する認識分子

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
AR062123A1 (es) * 2007-07-27 2008-10-15 Inst Nac De Tecnologia Agropec Dominio vhh monomerico derivado de anticuerpos de camelidos anti-vp6 dominio dimerico, metodo de inmunodeteccion de rotavirus, composiciones, metodos de prevencion y tratamiento de infecciones con rotavirus
JP2013527761A (ja) * 2010-05-06 2013-07-04 ノバルティス アーゲー 治療的低密度リポタンパク質関連タンパク質6(lrp6)多価抗体の組成物および使用方法
CN102942629B (zh) * 2012-11-21 2014-03-19 江苏省疾病预防控制中心 一种抗sftsv的人源抗体
CN104062443A (zh) * 2014-07-14 2014-09-24 江苏省疾病预防控制中心 一种病毒中和抗体定量检测试剂盒及其应用
KR101785290B1 (ko) * 2014-11-05 2017-10-18 대한민국 중증 열성 혈소판 감소 증후군 바이러스 감염 진단용 단클론항체, 이를 생산하는 하이브리도마 및 이 단클론항체를 사용하는 중증 열성 혈소판 감소 증후군 바이러스 감염 진단방법
KR102201391B1 (ko) * 2016-03-23 2021-01-11 서울대학교산학협력단 중증열성혈소판감소증후군 바이러스의 외막 당단백질에 결합하는 항체 및 이의 용도
CN107501396B (zh) * 2017-09-27 2019-12-13 源道隆(苏州)医学科技有限公司 一种用于诊断sfts患者预后情况的蛋白质及其应用
CN108178796B (zh) * 2017-12-28 2019-03-19 江苏省疾病预防控制中心 发热伴血小板减少综合征病毒糖蛋白定量检测试剂盒
CN112105637B (zh) * 2019-07-23 2022-12-06 源道隆(苏州)医学科技有限公司 可结合sftsv的纳米抗体及其应用

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009040780A (ja) * 1996-06-27 2009-02-26 Vlaams Interuniversitair Inst Voor Biotechnologie 標的分子の活性部位またはクレフトと特異的に相互作用する認識分子

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JP2021534727A (ja) 2021-12-16
WO2021012195A1 (zh) 2021-01-28
CN110713536A (zh) 2020-01-21
CN112105637B (zh) 2022-12-06
KR20210013000A (ko) 2021-02-03
CN110713536B (zh) 2021-08-31
CN110684102B (zh) 2022-10-21
JP7171737B2 (ja) 2022-11-15
CN112105637A (zh) 2020-12-18
CN110684102A (zh) 2020-01-14

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