KR102097844B1 - 바이오디젤을 만드는 재조합 미생물 - Google Patents

바이오디젤을 만드는 재조합 미생물 Download PDF

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KR102097844B1
KR102097844B1 KR1020157000238A KR20157000238A KR102097844B1 KR 102097844 B1 KR102097844 B1 KR 102097844B1 KR 1020157000238 A KR1020157000238 A KR 1020157000238A KR 20157000238 A KR20157000238 A KR 20157000238A KR 102097844 B1 KR102097844 B1 KR 102097844B1
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clostridium
biodiesel
microorganism
nucleic acid
fermentation
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KR20150023651A (ko
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펑민 리우
마이클 콥케
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란자테크 뉴질랜드 리미티드
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C10PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10LFUELS NOT OTHERWISE PROVIDED FOR; NATURAL GAS; SYNTHETIC NATURAL GAS OBTAINED BY PROCESSES NOT COVERED BY SUBCLASSES C10G OR C10K; LIQUIFIED PETROLEUM GAS; USE OF ADDITIVES TO FUELS OR FIRES; FIRE-LIGHTERS
    • C10L1/00Liquid carbonaceous fuels
    • C10L1/02Liquid carbonaceous fuels essentially based on components consisting of carbon, hydrogen, and oxygen only
    • C10L1/026Liquid carbonaceous fuels essentially based on components consisting of carbon, hydrogen, and oxygen only for compression ignition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/649Biodiesel, i.e. fatty acid alkyl esters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/0102Diacylglycerol O-acyltransferase (2.3.1.20)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01075Long-chain-alcohol O-fatty-acyltransferase (2.3.1.75)
    • C12R1/145
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/145Clostridium
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel
    • Y02E50/13
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
KR1020157000238A 2012-06-21 2013-06-21 바이오디젤을 만드는 재조합 미생물 Expired - Fee Related KR102097844B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261662467P 2012-06-21 2012-06-21
US61/662,467 2012-06-21
PCT/NZ2013/000108 WO2013191567A1 (en) 2012-06-21 2013-06-21 Recombinant microorganisms make biodiesel

Publications (2)

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KR20150023651A KR20150023651A (ko) 2015-03-05
KR102097844B1 true KR102097844B1 (ko) 2020-04-06

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US (1) US9347076B2 (https=)
EP (1) EP2864470B2 (https=)
JP (1) JP6466836B2 (https=)
KR (1) KR102097844B1 (https=)
CN (1) CN104640977B (https=)
BR (1) BR112014031876B1 (https=)
CA (1) CA2876178C (https=)
ES (1) ES2655214T5 (https=)
IN (1) IN2014DN10507A (https=)
MY (1) MY164882A (https=)
NO (1) NO2953671T3 (https=)
PL (1) PL2864470T5 (https=)
WO (1) WO2013191567A1 (https=)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201112231D0 (en) * 2011-07-15 2011-08-31 Verdant Bioproducts Ltd Micro-organism
US20130323820A1 (en) 2012-06-01 2013-12-05 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
US9347076B2 (en) 2012-06-21 2016-05-24 Lanzatech New Zealand Limited Recombinant microorganisms that make biodiesel
CN105940099A (zh) 2014-01-28 2016-09-14 朗泽科技新西兰有限公司 产生重组微生物的方法
JP6309304B2 (ja) * 2014-02-24 2018-04-11 積水化学工業株式会社 組換え細胞、並びに、1,4−ブタンジオールの生産方法
PL3209786T3 (pl) 2014-10-22 2023-10-30 Lanzatech Nz, Inc. Sposoby prowadzone w reaktorach wielostopniowych
EP4180806A1 (en) 2014-10-22 2023-05-17 LanzaTech NZ, Inc. Bioreactor and gas testing unit and method
US10131884B2 (en) 2015-02-23 2018-11-20 Lanzatech New Zealand Limited Recombinant acetogenic bacterium for the conversion of methane to products
BR112017025309A2 (pt) * 2015-05-27 2018-07-31 Lanzatech New Zealand Ltd micro-organismos geneticamente modificados para a fabricação de produtos derivados de corismato
MX391661B (es) 2015-10-13 2025-03-21 Lanzatech Nz Inc Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía
CA3010412C (en) 2015-12-03 2020-04-14 Lanzatech New Zealand Limited Arginine supplementation to improve efficiency in gas fermenting acetogens
US10358661B2 (en) 2015-12-28 2019-07-23 Lanzatech New Zealand Limited Microorganism with modified hydrogenase activity
ES2955708T3 (es) 2016-02-01 2023-12-05 Lanzatech Nz Inc Proceso integrado de fermentación y electrólisis
CA3015665C (en) 2016-02-26 2020-09-22 Lanzatech New Zealand Limited Crispr/cas systems for c1-fixing bacteria
EP3464559A4 (en) 2016-05-14 2020-02-12 Lanzatech, Inc. MODIFIED ALDEHYDE / FERREDOXIN OXYDOREDUCTASE MICROORGANISM AND RELATED METHODS
CN107217017B (zh) * 2017-05-27 2020-12-08 青岛农业大学 一株不动杆菌及其在石油降解中的应用
EP3679149B1 (en) 2017-09-08 2022-06-29 Lanzatech, Inc. Processes for metabolite production using hydrogen rich c1-containing substrates
MY196897A (en) 2017-12-19 2023-05-09 Lanzatech Inc Microorganisms and methods for the biological production of ethylene glycol
CN111683731B (zh) 2018-02-12 2022-09-02 朗泽科技有限公司 用于提高碳转化效率的工艺
EP3781668B1 (en) 2018-04-20 2023-10-04 Lanzatech, Inc. Fermentation process for producing ethanol
CA3120151C (en) 2018-11-19 2024-04-30 Lanzatech, Inc. Integration of fermentation and gasification
CN112969795A (zh) 2019-02-08 2021-06-15 朗泽科技有限公司 用于回收沸点接近的产物的方法
CN112955560A (zh) 2019-07-11 2021-06-11 朗泽科技有限公司 优化气体利用的方法
CN111088193B (zh) * 2020-01-10 2022-09-09 南京工业大学 一种提高食甲基丁酸杆菌电转频率的方法
US11932818B2 (en) 2020-03-16 2024-03-19 Lanzatech, Inc. Tail gas of gas fermentation to dry gasification feedstock
AU2021237368B2 (en) 2020-03-18 2025-05-08 Lanzatech, Inc. Fermentative production of 2-phenylethanol from gaseous substrates
EP4143325A4 (en) 2020-04-29 2024-09-11 Lanzatech, Inc. FERMENTATIVE PRODUCTION OF BETA-KETOADIPATE FROM GASEOUS SUBSTRATES
CA3224707A1 (en) 2020-06-06 2021-12-09 Lanzatech, Inc. Microorganism with knock-in at acetolactate decarboxylase gene locus
CN116348603B (zh) 2021-02-08 2024-07-02 朗泽科技有限公司 重组微生物及其用途
JP2024513395A (ja) 2021-04-09 2024-03-25 ランザテク,インコーポレイテッド 供給原料を提供するためのプロセス及び装置
US12241105B2 (en) 2021-07-20 2025-03-04 Lanzatech, Inc. Recombinant microorganisms and uses therefor
TW202307202A (zh) 2021-08-06 2023-02-16 美商朗澤科技有限公司 用於改良乙二醇之生物產生的微生物及方法
US12091648B2 (en) 2021-11-03 2024-09-17 Lanzatech, Inc. System and method for generating bubbles in a vessel
US12280331B2 (en) 2022-04-29 2025-04-22 Lanzatech, Inc. Low residence time gas separator
US12077800B2 (en) 2022-06-16 2024-09-03 Lanzatech, Inc. Liquid distributor system and process of liquid distribution
WO2023250382A1 (en) 2022-06-21 2023-12-28 Lanzatech, Inc. Microorganisms and methods for the continuous co-production of tandem repeat proteins and chemical products from c1-substrates
AU2023289395A1 (en) 2022-06-21 2025-01-09 Lanzatech, Inc. Microorganisms and methods for the continuous co-production of high-value, specialized proteins and chemical products from c1-substrates
WO2024036187A1 (en) 2022-08-10 2024-02-15 Lanzatech, Inc. Carbon sequestration in soils with production of chemical products
WO2024253883A1 (en) 2023-06-05 2024-12-12 Lanzatech, Inc. Integrated gas fermentation and carbon black processes
WO2024253882A1 (en) 2023-06-05 2024-12-12 Lanzatech, Inc. Integrated gas fermentation

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5173429A (en) 1990-11-09 1992-12-22 The Board Of Trustees Of The University Of Arkansas Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism
US5593886A (en) 1992-10-30 1997-01-14 Gaddy; James L. Clostridium stain which produces acetic acid from waste gases
UA72220C2 (uk) 1998-09-08 2005-02-15 Байоенджініерінг Рісорсиз, Інк. Незмішувана з водою суміш розчинник/співрозчинник для екстрагування оцтової кислоти, спосіб одержання оцтової кислоти (варіанти), спосіб анаеробного мікробного бродіння для одержання оцтової кислоти (варіанти), модифікований розчинник та спосіб його одержання
DK1303629T3 (da) 2000-07-25 2006-10-30 Emmaus Foundation Inc Fremgangsmåde til forögelse af ethanolproduktion fra mikrobiel fermetering
DE102004052115A1 (de) * 2004-10-26 2006-04-27 Westfälische Wilhelms-Universität Münster Mikroorganismen zur Herstellung von Fettsäureestern, Verfahren zu deren Herstellung und deren Verwendung
EP2024491B1 (en) * 2006-05-19 2014-11-19 LS9, Inc. Production of fatty acids and derivatives thereof
US7704723B2 (en) 2006-08-31 2010-04-27 The Board Of Regents For Oklahoma State University Isolation and characterization of novel clostridial species
CA3178593A1 (en) * 2007-03-28 2008-10-02 Genomatica, Inc. Enhanced production of fatty acid derivatives
US20100199548A1 (en) * 2007-07-06 2010-08-12 Ls9, Inc. Systems and methods for the production of fatty esters
CN102876609A (zh) 2007-11-13 2013-01-16 兰扎泰克新西兰有限公司 新型菌及其使用方法
GB0801787D0 (en) * 2008-01-31 2008-03-05 Reclaim Resources Ltd Apparatus and method for treating waste
US8048654B2 (en) * 2010-06-09 2011-11-01 Joule Unlimited Technologies, Inc. Methods and compositions for the recombinant biosynthesis of fatty acids and esters
US20100071259A1 (en) * 2008-08-18 2010-03-25 Ls9, Inc. Systems and methods for production of mixed fatty esters
CA2758298A1 (en) * 2009-04-10 2010-10-14 Ls9, Inc. Production of commercial biodiesel from genetically modified microorganisms
BRPI1009980A2 (pt) 2009-05-01 2015-08-25 Univ California Produtos de ésteres de ácidos graxos a partir de polímeros de biomassa
US8143037B2 (en) 2010-03-19 2012-03-27 Coskata, Inc. Ethanologenic Clostridium species, Clostridium coskatii
CN103282505A (zh) * 2010-08-26 2013-09-04 新西兰郎泽科技公司 通过发酵产生乙醇和乙烯的方法
US20110236941A1 (en) * 2010-10-22 2011-09-29 Lanzatech New Zealand Limited Recombinant microorganism and methods of production thereof
BR112013021524A2 (pt) 2011-02-25 2017-06-13 Lanzatech New Zealand Ltd micro-organismos recombinantes e usos dos mesmos
CN102492672A (zh) * 2011-11-26 2012-06-13 宁波大学 一种催化二酰甘油酰基化的酶
US9347076B2 (en) 2012-06-21 2016-05-24 Lanzatech New Zealand Limited Recombinant microorganisms that make biodiesel

Also Published As

Publication number Publication date
MY164882A (en) 2018-01-30
ES2655214T5 (es) 2021-10-11
IN2014DN10507A (https=) 2015-08-21
CA2876178A1 (en) 2013-12-27
JP2015519918A (ja) 2015-07-16
WO2013191567A1 (en) 2013-12-27
CN104640977A (zh) 2015-05-20
EP2864470A4 (en) 2015-12-16
EP2864470A1 (en) 2015-04-29
EP2864470B2 (en) 2020-12-23
EP2864470B1 (en) 2017-10-04
PL2864470T5 (pl) 2021-05-17
CN104640977B (zh) 2019-04-12
KR20150023651A (ko) 2015-03-05
US9347076B2 (en) 2016-05-24
JP6466836B2 (ja) 2019-02-06
ES2655214T3 (es) 2018-02-19
NO2953671T3 (https=) 2018-03-17
CA2876178C (en) 2017-02-28
BR112014031876B1 (pt) 2022-05-10
BR112014031876A2 (pt) 2017-08-01
PL2864470T3 (pl) 2018-05-30
US20130344547A1 (en) 2013-12-26

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