KR102035187B1 - 지질-기반 나노입자들 - Google Patents

지질-기반 나노입자들 Download PDF

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Publication number
KR102035187B1
KR102035187B1 KR1020197007384A KR20197007384A KR102035187B1 KR 102035187 B1 KR102035187 B1 KR 102035187B1 KR 1020197007384 A KR1020197007384 A KR 1020197007384A KR 20197007384 A KR20197007384 A KR 20197007384A KR 102035187 B1 KR102035187 B1 KR 102035187B1
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South Korea
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liposome composition
phospholipid
aromatic
alkyl
polymer
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Expired - Fee Related
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KR1020197007384A
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English (en)
Korean (ko)
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KR20190031334A (ko
Inventor
아난스 안나프라가다
제이슨 엘. 에릭슨
에릭 에이. 타니품
인드라니 다스굽타
스티븐 씨. 쿡
Original Assignee
보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템
알제카 바이오사이언시스, 엘엘씨
보드 오브 리전츠 오브 더 유니버시티 오브 휴스턴 시스템
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46966277&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR102035187(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템, 알제카 바이오사이언시스, 엘엘씨, 보드 오브 리전츠 오브 더 유니버시티 오브 휴스턴 시스템 filed Critical 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템
Publication of KR20190031334A publication Critical patent/KR20190031334A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1812—Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions
    • A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
KR1020197007384A 2011-04-06 2012-04-06 지질-기반 나노입자들 Expired - Fee Related KR102035187B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161472605P 2011-04-06 2011-04-06
US61/472,605 2011-04-06
PCT/US2012/032649 WO2012139080A2 (en) 2011-04-06 2012-04-06 Lipid-based nanoparticles

Related Parent Applications (1)

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KR1020137029510A Division KR101973063B1 (ko) 2011-04-06 2012-04-06 지질-기반 나노입자들

Publications (2)

Publication Number Publication Date
KR20190031334A KR20190031334A (ko) 2019-03-25
KR102035187B1 true KR102035187B1 (ko) 2019-11-08

Family

ID=46966277

Family Applications (2)

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KR1020197007384A Expired - Fee Related KR102035187B1 (ko) 2011-04-06 2012-04-06 지질-기반 나노입자들
KR1020137029510A Expired - Fee Related KR101973063B1 (ko) 2011-04-06 2012-04-06 지질-기반 나노입자들

Family Applications After (1)

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KR1020137029510A Expired - Fee Related KR101973063B1 (ko) 2011-04-06 2012-04-06 지질-기반 나노입자들

Country Status (14)

Country Link
US (1) US9801957B2 (enExample)
EP (2) EP3366313A1 (enExample)
JP (3) JP6212032B2 (enExample)
KR (2) KR102035187B1 (enExample)
CN (1) CN104144708B (enExample)
AU (3) AU2012239888B9 (enExample)
BR (1) BR112013025633A2 (enExample)
CA (1) CA2831480C (enExample)
DK (1) DK2694116T3 (enExample)
ES (1) ES2685824T3 (enExample)
MX (1) MX357227B (enExample)
PL (1) PL2694116T3 (enExample)
PT (1) PT2694116T (enExample)
WO (1) WO2012139080A2 (enExample)

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EP3366313A1 (en) 2011-04-06 2018-08-29 Board Of Regents Of the University Of Texas System Lipid-based nanoparticles
JP6130401B2 (ja) 2012-01-20 2017-05-17 アンナプラガダ，アナンス 医学画像を客観的に特徴付けるための方法および組成物
US9512092B2 (en) 2013-12-12 2016-12-06 Albert Einstein College Of Medicine, Inc. Retinoic acid receptor antagonists as chaperone-mediated autophagy modulators and uses thereof
CN107106708B (zh) * 2014-10-08 2021-06-18 德克萨斯州儿童医院 使用脂质体进行的淀粉样蛋白斑mri成像
GB201509934D0 (en) 2015-06-08 2015-07-22 King S College London Nanoparticles
WO2017201091A1 (en) * 2016-05-16 2017-11-23 The Board Of Regents Of The University Of Texas System COMPOSITIONS FOR THE DELIVERY OF tRNA AS NANOPARTICLES AND METHODS OF USE THEREWITH
CN110022859B (zh) * 2016-11-30 2022-10-28 德克萨斯州儿童医院 具有独特的mr特征用于脂质体19f mri探针的亲水性氟化分子
EP3914230A4 (en) * 2019-01-24 2023-06-07 Alzeca Biosciences, Llc <SMALLCAPS/>? ? ?FUNCTIONALIZED LIPOSOMES FOR IMAGE MISFOLDED PROTEINS
CN115916263B (zh) * 2020-01-29 2025-10-03 德克萨斯儿童医院 用于淀粉样蛋白沉积mri的靶向对比剂
US11779664B2 (en) 2020-02-12 2023-10-10 Texas Children's Hospital Targeted contrast agents for MRI of alpha-synuclein deposition
CN115279424A (zh) * 2020-02-12 2022-11-01 德克萨斯儿童医院 用于α-突触核蛋白沉积MRI的靶向对比剂

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US20070160658A1 (en) * 2005-10-20 2007-07-12 The Penn State Research Foundation Delivery system for diagnostic and therapeutic agents
WO2008054498A2 (en) 2006-04-07 2008-05-08 The Board Of Trustees Of The University Of Illinois Hydrophilic polymer-conjugated lipids for peptide and protein folding disorders

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US20050152963A1 (en) 2003-12-18 2005-07-14 Joerg Huwyler Liposome compositions
US20070160658A1 (en) * 2005-10-20 2007-07-12 The Penn State Research Foundation Delivery system for diagnostic and therapeutic agents
WO2008054498A2 (en) 2006-04-07 2008-05-08 The Board Of Trustees Of The University Of Illinois Hydrophilic polymer-conjugated lipids for peptide and protein folding disorders

Also Published As

Publication number Publication date
CA2831480A1 (en) 2012-10-11
PL2694116T3 (pl) 2018-12-31
US9801957B2 (en) 2017-10-31
AU2017232156A1 (en) 2017-10-12
JP2014523854A (ja) 2014-09-18
AU2012239888B2 (en) 2017-06-22
MX2013011231A (es) 2015-03-05
AU2017232156C1 (en) 2019-10-24
JP6533813B2 (ja) 2019-06-19
WO2012139080A2 (en) 2012-10-11
PT2694116T (pt) 2018-10-12
CN104144708B (zh) 2017-07-28
JP2019151664A (ja) 2019-09-12
ES2685824T3 (es) 2018-10-11
AU2012239888A2 (en) 2014-05-08
HK1203827A1 (en) 2015-11-06
JP6212032B2 (ja) 2017-10-18
KR20140074868A (ko) 2014-06-18
KR101973063B1 (ko) 2019-04-30
CN104144708A (zh) 2014-11-12
AU2019246775A1 (en) 2019-10-31
EP2694116A4 (en) 2015-06-03
AU2012239888A1 (en) 2013-11-07
EP3366313A1 (en) 2018-08-29
CA2831480C (en) 2020-09-29
KR20190031334A (ko) 2019-03-25
EP2694116A2 (en) 2014-02-12
MX357227B (es) 2018-07-02
EP2694116B1 (en) 2018-06-13
AU2012239888B9 (en) 2017-10-12
DK2694116T3 (en) 2018-09-03
WO2012139080A3 (en) 2014-05-01
US20120258044A1 (en) 2012-10-11
AU2017232156B2 (en) 2019-07-11
BR112013025633A2 (pt) 2017-08-08
JP2018035167A (ja) 2018-03-08

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