MX357227B - Nanoparticulas basadas en lipidos. - Google Patents
Nanoparticulas basadas en lipidos.Info
- Publication number
- MX357227B MX357227B MX2013011231A MX2013011231A MX357227B MX 357227 B MX357227 B MX 357227B MX 2013011231 A MX2013011231 A MX 2013011231A MX 2013011231 A MX2013011231 A MX 2013011231A MX 357227 B MX357227 B MX 357227B
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- lipid
- based nanoparticles
- amyloid
- liposomal
- Prior art date
Links
- 150000002632 lipids Chemical class 0.000 title abstract 2
- 239000002105 nanoparticle Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 5
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 102000013455 Amyloid beta-Peptides Human genes 0.000 abstract 1
- 108010090849 Amyloid beta-Peptides Proteins 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1806—Suspensions, emulsions, colloids, dispersions
- A61K49/1812—Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
- A61K49/0461—Dispersions, colloids, emulsions or suspensions
- A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dispersion Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161472605P | 2011-04-06 | 2011-04-06 | |
| PCT/US2012/032649 WO2012139080A2 (en) | 2011-04-06 | 2012-04-06 | Lipid-based nanoparticles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013011231A MX2013011231A (es) | 2015-03-05 |
| MX357227B true MX357227B (es) | 2018-07-02 |
Family
ID=46966277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013011231A MX357227B (es) | 2011-04-06 | 2012-04-06 | Nanoparticulas basadas en lipidos. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9801957B2 (enExample) |
| EP (2) | EP2694116B1 (enExample) |
| JP (3) | JP6212032B2 (enExample) |
| KR (2) | KR101973063B1 (enExample) |
| CN (1) | CN104144708B (enExample) |
| AU (3) | AU2012239888B9 (enExample) |
| BR (1) | BR112013025633A2 (enExample) |
| CA (1) | CA2831480C (enExample) |
| DK (1) | DK2694116T3 (enExample) |
| ES (1) | ES2685824T3 (enExample) |
| MX (1) | MX357227B (enExample) |
| PL (1) | PL2694116T3 (enExample) |
| PT (1) | PT2694116T (enExample) |
| WO (1) | WO2012139080A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9801957B2 (en) * | 2011-04-06 | 2017-10-31 | Ananth Annapragada | Lipid-based nanoparticles |
| EP2756459B1 (en) | 2012-01-20 | 2020-12-09 | Ananth Annapragada | Methods and compositions for objectively characterizing medical images |
| US9512092B2 (en) * | 2013-12-12 | 2016-12-06 | Albert Einstein College Of Medicine, Inc. | Retinoic acid receptor antagonists as chaperone-mediated autophagy modulators and uses thereof |
| EP3542828A1 (en) * | 2014-10-08 | 2019-09-25 | Texas Children's Hospital | Mri imaging of amyloid plaque using liposomes |
| GB201509934D0 (en) | 2015-06-08 | 2015-07-22 | King S College London | Nanoparticles |
| PL3458074T3 (pl) * | 2016-05-16 | 2024-11-12 | Board Of Regents Of The University Of Texas System | KOMPOZYCJA DO DOSTARCZANIA tRNA W POSTACI NANOCZĄSTEK I SPOSOBY ICH STOSOWANIA |
| EP3548002B1 (en) | 2016-11-30 | 2025-04-30 | Texas Children's Hospital | Hydrophilic fluorinated molecules for liposomal 19f mri probes with unique mr signatures |
| JP7545393B2 (ja) * | 2019-01-24 | 2024-09-04 | アルゼカ バイオサイエンシズ、エルエルシー | 誤って折りたたまれたタンパク質を画像化するための機能化リポソーム |
| KR102546470B1 (ko) * | 2020-01-29 | 2023-06-21 | 텍사스 칠드런스 하스피탈 | 아밀로이드 침착의 mri용 표적 조영제 |
| US11779664B2 (en) | 2020-02-12 | 2023-10-10 | Texas Children's Hospital | Targeted contrast agents for MRI of alpha-synuclein deposition |
| WO2021163585A1 (en) | 2020-02-12 | 2021-08-19 | Texas Children's Hospital | Targeted contrast agents for mri of alpha-synuclein deposition |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4331751A (en) * | 1980-11-17 | 1982-05-25 | Eastman Kodak Company | Electrically photosensitive materials and elements for photoelectrophoretic imaging processes |
| US5204085A (en) | 1985-01-08 | 1993-04-20 | Mallinckrodt Medical, Inc. | Method for enhancing the safety of metal-ligand chelates as X-ray contrast agents |
| US5674468A (en) | 1992-03-06 | 1997-10-07 | Nycomed Imaging As | Contrast agents comprising gas-containing or gas-generating polymer microparticles or microballoons |
| CN1148812A (zh) | 1994-03-28 | 1997-04-30 | 尼科梅德成像有限公司 | “脂质体” |
| US6071532A (en) | 1996-10-15 | 2000-06-06 | Emory University | Synthesis of glycophospholipid and peptide-phospholipid conjugates and uses thereof |
| JP4829454B2 (ja) | 1999-11-30 | 2011-12-07 | ジ・アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・ザ・ユニバーシティ・オブ・アリゾナ | 放射線感受性リポソーム |
| WO2002028441A2 (en) | 2000-10-04 | 2002-04-11 | California Institute Of Technology | Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits |
| WO2002094191A2 (en) * | 2001-05-23 | 2002-11-28 | New York University | Detection of alzheimer's amyloid by magnetic resonance imaging |
| AU2003217950A1 (en) | 2002-03-05 | 2003-09-22 | Cleveland State University | Agglomerated particles for aerosol drug delivery |
| EP1641742A4 (en) | 2003-05-01 | 2006-11-29 | Nst Neurosurvival Technologies | COMPOUNDS BINDING SELECTIVELY TO MEMBRANES OF APOPTOTIC CELLS |
| US7208174B2 (en) * | 2003-12-18 | 2007-04-24 | Hoffmann-La Roche Inc. | Liposome compositions |
| US20100031378A1 (en) | 2008-08-04 | 2010-02-04 | Edwards Joel A | Novel gene disruptions, compositions and methods relating thereto |
| US8357351B2 (en) | 2004-04-21 | 2013-01-22 | Ananth Annapragada | Nano-scale contrast agents and methods of use |
| US7713517B2 (en) | 2004-04-21 | 2010-05-11 | Marval Biosciences, Inc. | Compositions and methods for enhancing contrast in imaging |
| US7803351B2 (en) * | 2004-08-20 | 2010-09-28 | Washington University | Blood brain barrier permeation peptides |
| WO2006032705A2 (en) * | 2004-09-23 | 2006-03-30 | Guerbet | Contrast agents encapsulating systems for cest imaging |
| EP1888034A2 (en) * | 2005-05-26 | 2008-02-20 | Yissum Research Development Company, of The Hebrew University of Jerusalem | Compositions and methods using same for delivering agents into a target organ protected by a blood barrier |
| WO2007048019A2 (en) * | 2005-10-20 | 2007-04-26 | The Penn State Research Foundation | Delivery system for diagnostic and therapeutic agents |
| WO2008054498A2 (en) * | 2006-04-07 | 2008-05-08 | The Board Of Trustees Of The University Of Illinois | Hydrophilic polymer-conjugated lipids for peptide and protein folding disorders |
| US20090123047A1 (en) | 2007-03-21 | 2009-05-14 | Yfantis Spyros A | Method and system for characterizing prostate images |
| EP1982733A1 (en) | 2007-04-17 | 2008-10-22 | Bayer Schering Pharma Aktiengesellschaft | Use of a contrast agent for magnetic resonance imaging of endoleaks |
| CA2695204A1 (en) | 2007-07-26 | 2009-01-29 | Nanoscan Imaging, Llc | Methods for imaging using improved nanoparticulate contrast agents |
| CA2708028A1 (en) | 2007-12-05 | 2009-06-11 | Marval Biosciences, Inc. | Nano-scale contrast agents and methods of use |
| CN102037004A (zh) | 2008-01-08 | 2011-04-27 | 生物种属学股份公司 | 使用寡糖基转移酶的多肽的糖缀合 |
| ITMI20081052A1 (it) | 2008-06-10 | 2009-12-11 | Univ Milano Bicocca | Liposomi in grado di legare efficacemente il peptide beta-amiloide |
| WO2009152445A1 (en) | 2008-06-13 | 2009-12-17 | Marval Biosciences, Inc. | Imaging of atherosclerotic plaques using liposomal imaging agents |
| WO2010017094A2 (en) * | 2008-07-31 | 2010-02-11 | The General Hospital Corporation | CURCUMIN DERIVATIVES FOR AMYLOID-β PLAQUE IMAGING |
| AR074760A1 (es) | 2008-12-18 | 2011-02-09 | Metabolex Inc | Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico. |
| JP2012520898A (ja) | 2009-03-19 | 2012-09-10 | マーヴァル バイオサイエンシーズ，インコーポレイテッド | 画像化におけるコントラスト強調のための組成物および方法 |
| US9334304B2 (en) * | 2009-04-02 | 2016-05-10 | The Johns Hopkins University | Self-assembling peptides bearing organic electronic functionality and applications employing the same |
| US20120263646A1 (en) | 2009-10-15 | 2012-10-18 | Guerbet | Imaging agents and their use for the diagnostic in vivo of neurodegenerative diseases, notably alzheimer's disease and derivative diseases |
| ES2526124T3 (es) | 2010-06-16 | 2015-01-07 | Cymabay Therapeutics, Inc. | Agonistas del receptor GPR120 y sus usos |
| AU2012223210B2 (en) | 2011-03-02 | 2016-12-22 | Board Of Regents Of The University Of Texas System | Vesicle compositions |
| US9801957B2 (en) * | 2011-04-06 | 2017-10-31 | Ananth Annapragada | Lipid-based nanoparticles |
| GB201112056D0 (en) | 2011-07-14 | 2011-08-31 | Univ Leuven Kath | Antibodies |
| EP2756459B1 (en) | 2012-01-20 | 2020-12-09 | Ananth Annapragada | Methods and compositions for objectively characterizing medical images |
| WO2013164763A2 (en) | 2012-04-30 | 2013-11-07 | Innovative Health Diagnostics | A biological complex specific for alzheimer's disease detection in vitro and use thereof |
| AU2014240042C1 (en) | 2013-03-14 | 2019-09-05 | Celltaxis, Llc | Inhibitors of leukotriene A4 hydrolase |
| EP3542828A1 (en) | 2014-10-08 | 2019-09-25 | Texas Children's Hospital | Mri imaging of amyloid plaque using liposomes |
-
2012
- 2012-04-06 US US13/441,816 patent/US9801957B2/en not_active Expired - Fee Related
- 2012-04-06 ES ES12767275.6T patent/ES2685824T3/es active Active
- 2012-04-06 PT PT12767275T patent/PT2694116T/pt unknown
- 2012-04-06 AU AU2012239888A patent/AU2012239888B9/en not_active Ceased
- 2012-04-06 CA CA2831480A patent/CA2831480C/en not_active Expired - Fee Related
- 2012-04-06 PL PL12767275T patent/PL2694116T3/pl unknown
- 2012-04-06 BR BR112013025633A patent/BR112013025633A2/pt not_active Application Discontinuation
- 2012-04-06 KR KR1020137029510A patent/KR101973063B1/ko not_active Expired - Fee Related
- 2012-04-06 JP JP2014504057A patent/JP6212032B2/ja not_active Expired - Fee Related
- 2012-04-06 DK DK12767275.6T patent/DK2694116T3/en active
- 2012-04-06 MX MX2013011231A patent/MX357227B/es active IP Right Grant
- 2012-04-06 KR KR1020197007384A patent/KR102035187B1/ko not_active Expired - Fee Related
- 2012-04-06 WO PCT/US2012/032649 patent/WO2012139080A2/en not_active Ceased
- 2012-04-06 EP EP12767275.6A patent/EP2694116B1/en not_active Not-in-force
- 2012-04-06 EP EP18167725.3A patent/EP3366313A1/en not_active Withdrawn
- 2012-04-06 CN CN201280017548.6A patent/CN104144708B/zh not_active Expired - Fee Related
-
2017
- 2017-09-14 JP JP2017176383A patent/JP6533813B2/ja not_active Expired - Fee Related
- 2017-09-21 AU AU2017232156A patent/AU2017232156C1/en not_active Ceased
-
2019
- 2019-05-27 JP JP2019098174A patent/JP2019151664A/ja active Pending
- 2019-10-08 AU AU2019246775A patent/AU2019246775A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |