KR102002147B1 - 알코올 독성을 감소시키기 위한 방법들 및 조성물들 - Google Patents

알코올 독성을 감소시키기 위한 방법들 및 조성물들 Download PDF

Info

Publication number
KR102002147B1
KR102002147B1 KR1020147015619A KR20147015619A KR102002147B1 KR 102002147 B1 KR102002147 B1 KR 102002147B1 KR 1020147015619 A KR1020147015619 A KR 1020147015619A KR 20147015619 A KR20147015619 A KR 20147015619A KR 102002147 B1 KR102002147 B1 KR 102002147B1
Authority
KR
South Korea
Prior art keywords
delete delete
acetaldehyde
composition
subject
acetaldehyde dehydrogenase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020147015619A
Other languages
English (en)
Korean (ko)
Other versions
KR20140106549A (ko
Inventor
폴 텔러레이
유스케 유시다
Original Assignee
더 존스 홉킨스 유니버시티
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 더 존스 홉킨스 유니버시티 filed Critical 더 존스 홉킨스 유니버시티
Publication of KR20140106549A publication Critical patent/KR20140106549A/ko
Application granted granted Critical
Publication of KR102002147B1 publication Critical patent/KR102002147B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/26—Cyanate or isocyanate esters; Thiocyanate or isothiocyanate esters
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Addiction (AREA)
  • Emergency Medicine (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020147015619A 2011-11-22 2012-11-21 알코올 독성을 감소시키기 위한 방법들 및 조성물들 Active KR102002147B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161562559P 2011-11-22 2011-11-22
US61/562,559 2011-11-22
US201161568721P 2011-12-09 2011-12-09
US61/568,721 2011-12-09
PCT/US2012/066340 WO2013078371A2 (en) 2011-11-22 2012-11-21 Methods and compositions for reducing alcohol toxicity

Publications (2)

Publication Number Publication Date
KR20140106549A KR20140106549A (ko) 2014-09-03
KR102002147B1 true KR102002147B1 (ko) 2019-07-19

Family

ID=48470418

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147015619A Active KR102002147B1 (ko) 2011-11-22 2012-11-21 알코올 독성을 감소시키기 위한 방법들 및 조성물들

Country Status (6)

Country Link
US (2) US20150087702A1 (enExample)
EP (1) EP2782583B1 (enExample)
JP (1) JP6437823B2 (enExample)
KR (1) KR102002147B1 (enExample)
CN (1) CN104520311B (enExample)
WO (1) WO2013078371A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160030364A1 (en) * 2013-04-05 2016-02-04 Manuka Health New Zealand Limited Therapeutic Compositions and Uses Thereof
CN103396348B (zh) * 2013-08-21 2015-05-20 昆明龙津药业股份有限公司 蔊菜素的衍生物以及在制备抗癌药物中的应用
JP6855157B2 (ja) * 2014-10-06 2021-04-07 扶桑化学工業株式会社 水中動物用飼料、水中動物用発育向上剤、および、それらを用いた養殖魚の飼育方法
WO2016168450A1 (en) 2015-04-16 2016-10-20 The Research Foundation For The State University Of New York Acetylenic cyanoenones as therapeutics for inflammation and carcinogenesis
CN105251025B (zh) * 2015-11-11 2018-11-27 福州大学 Aldh2基因在制备预防苯乙烯致遗传毒性药物中的应用
JP2017195809A (ja) * 2016-04-27 2017-11-02 佐々木食品工業株式会社 アセトアルデヒドの代謝促進用食品組成物及びアセトアルデヒドの代謝促進剤
CN107789612A (zh) * 2016-08-31 2018-03-13 李镇坚 一种中药水果复合固体解酒糖及制备工艺
JP6867823B2 (ja) * 2017-02-13 2021-05-12 サッポロビール株式会社 アセトアルデヒドデヒドロゲナーゼ活性促進剤
US10849938B2 (en) 2017-09-13 2020-12-01 ZBiotics Company Gene expression system for probiotic microorganisms
CN107950726A (zh) * 2017-11-27 2018-04-24 广州六顺生物科技有限公司 一种具有解酒护肝作用的凝胶糖果、制备方法和应用
CN110101849B (zh) * 2019-04-12 2023-11-10 暨南大学 一种酶催化解酒作用的组合物及其制备方法与应用
CN110538173A (zh) * 2019-08-20 2019-12-06 郑州大学第一附属医院 异硫氰酸酯类化合物在制备食管癌靶向药中的应用
AU2020363927A1 (en) * 2019-10-10 2022-04-28 Zobrius Pharma As Improved anti-hangover composition, its preparation and uses
KR102460545B1 (ko) 2020-02-18 2022-10-31 주식회사 피코엔텍 신규한 돌연변이 효모를 함유하는 천식 억제용 조성물
CN111437280A (zh) * 2020-04-29 2020-07-24 重庆燕盈生物科技有限公司 一种基于雷公藤红素的新用途及其应用
JP2023546022A (ja) 2020-10-08 2023-11-01 ジーバイオティクス カンパニー 腸内での繊維合成酵素の発現のための操作されたプロバイオティクス
CN118490676B (zh) * 2024-07-18 2024-09-13 暨南大学 杨芽黄素在制备延缓卵巢衰老和/或修复损伤卵巢和/或重建卵巢功能药物中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007016953A1 (en) 2005-07-29 2007-02-15 Matuschka-Greiffenclau Markus Composition for reducing alcohol induced liver cancer risk
CN103202838A (zh) 2013-04-16 2013-07-17 缪为民 一种具有肝脏保护作用的植物提取物组合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5725895B1 (en) 1995-09-15 2000-10-10 Hopkins J School Of Medicine Method of preparing food product from cruciferous seeds
KR20020014978A (ko) * 2000-08-19 2002-02-27 김기성 숙취제거 향의 조성물
US20050271754A1 (en) * 2004-06-07 2005-12-08 Cochrane Patrick W Composition for prevention or treatment of an alcohol hangover
RU2292899C2 (ru) * 2004-06-29 2007-02-10 Дмитрий Николаевич Мясников Средство и способ профилактики и уменьшения неблагоприятных проявлений острой алкогольной интоксикации (варианты) и способ получения средства
KR100661032B1 (ko) * 2005-04-19 2006-12-22 주식회사한국야쿠르트 간 기능 개선, 혈중 알코올 감소 및 항산화에 유효한조성물
ATE554663T1 (de) * 2005-07-29 2012-05-15 Tima Foundation Zusammensetzung zur steuerung des alkohol metabolismus und zur reduktion des risikos von alkoholbedingten krankheiten
US20080311276A1 (en) * 2007-06-12 2008-12-18 Kraft Foods Holdings, Inc. Production of Glucosinolates from Agricultural By-Products & Waste
WO2009094177A1 (en) * 2008-01-24 2009-07-30 Raptor Therapeutics Inc. Protopanaxadiol-type ginsenoside compositions and uses thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007016953A1 (en) 2005-07-29 2007-02-15 Matuschka-Greiffenclau Markus Composition for reducing alcohol induced liver cancer risk
CN103202838A (zh) 2013-04-16 2013-07-17 缪为民 一种具有肝脏保护作用的植物提取物组合物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Medical Hypotheses. 2001, Vol.56, No.1, pp.8-11*

Also Published As

Publication number Publication date
CN104520311B (zh) 2018-03-13
KR20140106549A (ko) 2014-09-03
JP2015509909A (ja) 2015-04-02
EP2782583A4 (en) 2016-04-13
WO2013078371A3 (en) 2014-12-04
US20210401791A1 (en) 2021-12-30
EP2782583B1 (en) 2019-09-25
US20150087702A1 (en) 2015-03-26
JP6437823B2 (ja) 2018-12-12
CN104520311A (zh) 2015-04-15
WO2013078371A2 (en) 2013-05-30
EP2782583A2 (en) 2014-10-01

Similar Documents

Publication Publication Date Title
KR20140106549A (ko) 알코올 독성을 감소시키기 위한 방법들 및 조성물들
KR102090836B1 (ko) 세포 정제를 촉진하기 위한 경구 제제
Krajka-Kuźniak et al. Betanin, a beetroot component, induces nuclear factor erythroid-2-related factor 2-mediated expression of detoxifying/antioxidant enzymes in human liver cell lines
Li et al. Reduction of aging-induced oxidative stress and activation of autophagy by bilberry anthocyanin supplementation via the AMPK–mTOR signaling pathway in aged female rats
Hussein et al. Astaxanthin, a carotenoid with potential in human health and nutrition
JP6591748B2 (ja) 自閉症の処置のための方法および組成物
Balstad et al. Coffee, broccoli and spices are strong inducers of electrophile response element‐dependent transcription in vitro and in vivo–Studies in electrophile response element transgenic mice
Ke et al. Tangeretin improves hepatic steatosis and oxidative stress through the Nrf2 pathway in high fat diet-induced nonalcoholic fatty liver disease mice
Kaiser et al. Capsaicinoids: Occurrence, chemistry, biosynthesis, and biological effects
Xu et al. Mitochondrial quality control: a pathophysiological mechanism and potential therapeutic target for chronic obstructive pulmonary disease
Townsend et al. Dietary broccoli mildly improves neuroinflammation in aged mice but does not reduce lipopolysaccharide-induced sickness behavior
Yuan et al. Bamboo leaf flavonoids ameliorate cyclic heat stress-induced oxidative damage in broiler liver through activation of Keap1-Nrf2 signaling pathway
Sahin et al. Capsaicinoids improve consequences of physical activity
Qin et al. Resveratrol enhances post-injury muscle regeneration by regulating antioxidant and mitochondrial biogenesis
Li et al. Role of melatonin in respiratory diseases
Tanaka Animal models of carcinogenesis in inflamed colorectum: potential use in chemoprevention study
Subbaiah et al. 6-Gingerol prevents free transition metal Ion [Fe (Ii)] Induced free radicals mediated alterations by In vitro and Ndv growth in chicken eggs by In ovo.
JP6441364B2 (ja) ジベンゾ−アルファ−ピロンを用いた体重増加制御
JP2024534971A (ja) セロリ種子抽出物を有効成分として含む筋力弱化関連疾患の予防、改善または治療用組成物
JP2023554187A (ja) 身体運動パフォーマンスを改善するため方法
CN110545831A (zh) Withania somnifera提取物提供针对空气污染相关疾病的保护的用途
Yunusova et al. The Influence of Monoammonium Salt of Glycyrrhizinic Acid and Acetylsalicylic Acid on Cardiac and Hematological Processes in Rats with Experimental Myocarditis
ルヒールヒーア タスキン The effects of sulforaphane on inflammation and oxidative stress and the mechanisms
Stagos et al. Research Article Extracts from the Mediterranean Food Plants Carthamus lanatus, Cichorium intybus, and Cichorium spinosum Enhanced GSH Levels and Increased Nrf2 Expression in Human Endothelial Cells
WO2020036483A1 (en) Composition comprising oil palm phenolics for use in the treatment and prevention of colon diseases and for promoting and maintaining gut and general health

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
AMND Amendment
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

AMND Amendment
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E601 Decision to refuse application
PE0601 Decision on rejection of patent

St.27 status event code: N-2-6-B10-B15-exm-PE0601

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T13-X000 Administrative time limit extension granted

St.27 status event code: U-3-3-T10-T13-oth-X000

AMND Amendment
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PX0901 Re-examination

St.27 status event code: A-2-3-E10-E12-rex-PX0901

PX0701 Decision of registration after re-examination

St.27 status event code: A-3-4-F10-F13-rex-PX0701

X701 Decision to grant (after re-examination)
GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 7

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 8

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-OTH-PR1001 (AS PROVIDED BY THE NATIONAL OFFICE)

Year of fee payment: 8