KR101961076B1 - 핵산 시료의 조제 방법 - Google Patents

핵산 시료의 조제 방법 Download PDF

Info

Publication number
KR101961076B1
KR101961076B1 KR1020187018686A KR20187018686A KR101961076B1 KR 101961076 B1 KR101961076 B1 KR 101961076B1 KR 1020187018686 A KR1020187018686 A KR 1020187018686A KR 20187018686 A KR20187018686 A KR 20187018686A KR 101961076 B1 KR101961076 B1 KR 101961076B1
Authority
KR
South Korea
Prior art keywords
nucleic acid
skin
subject
rna
ssl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020187018686A
Other languages
English (en)
Korean (ko)
Other versions
KR20180081624A (ko
Inventor
다카요시 이노우에
아키라 하치야
Original Assignee
카오카부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 카오카부시키가이샤 filed Critical 카오카부시키가이샤
Publication of KR20180081624A publication Critical patent/KR20180081624A/ko
Application granted granted Critical
Publication of KR101961076B1 publication Critical patent/KR101961076B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B5/00—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts
    • B32B5/18—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by features of a layer of foamed material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/166—Oligonucleotides used as internal standards, controls or normalisation probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020187018686A 2016-07-08 2017-06-07 핵산 시료의 조제 방법 Active KR101961076B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2016070343 2016-07-08
JPPCT/JP2016/070343 2016-07-08
PCT/JP2017/021040 WO2018008319A1 (ja) 2016-07-08 2017-06-07 核酸試料の調製方法

Publications (2)

Publication Number Publication Date
KR20180081624A KR20180081624A (ko) 2018-07-16
KR101961076B1 true KR101961076B1 (ko) 2019-03-21

Family

ID=60912100

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020187018686A Active KR101961076B1 (ko) 2016-07-08 2017-06-07 핵산 시료의 조제 방법

Country Status (6)

Country Link
US (1) US11913061B2 (https=)
EP (2) EP3372693B1 (https=)
JP (2) JP2018000206A (https=)
KR (1) KR101961076B1 (https=)
CN (1) CN108699589B (https=)
WO (1) WO2018008319A1 (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102731755B1 (ko) 2018-11-01 2024-11-20 카오카부시키가이샤 피험체의 피부 세포에서 유래하는 핵산의 조제 방법
EP4089104A4 (en) * 2020-01-10 2024-02-21 Kao Corporation METHOD FOR NUCLEIC ACID AMPLIFICATION
JP7555858B2 (ja) * 2020-03-11 2024-09-25 花王株式会社 皮膚表上脂質由来ｒｎａの調製方法
EP4141114A4 (en) * 2020-04-24 2024-09-11 Kao Corporation METHODS FOR DETECTING THE SEVERITY OF PREMENSTRUAL SYNDROME
WO2021221138A1 (ja) 2020-05-01 2021-11-04 花王株式会社 アトピー性皮膚炎の検出方法
JP2021175382A (ja) * 2020-05-01 2021-11-04 花王株式会社 乳幼児アトピー性皮膚炎の検出方法
JP2021175958A (ja) * 2020-05-01 2021-11-04 花王株式会社 アトピー性皮膚炎検出用タンパク質マーカーの調製方法
JP2021175381A (ja) * 2020-05-01 2021-11-04 花王株式会社 アトピー性皮膚炎の検出方法
CN115605608A (zh) * 2020-05-14 2023-01-13 花王株式会社（Jp） 帕金森氏病的检测方法
JP7712792B2 (ja) 2020-05-14 2025-07-24 花王株式会社 Ｒｎａ情報のデータ処理方法
CN115803450A (zh) 2020-07-10 2023-03-14 花王株式会社 特应性皮炎的重症度的检测方法
EP4206323A4 (en) 2020-08-28 2024-08-28 Kao Corporation Rna storage method
JP7840855B2 (ja) 2020-08-28 2026-04-06 花王株式会社 検体保存具
WO2022059745A1 (ja) 2020-09-16 2022-03-24 花王株式会社 乳幼児アトピー性皮膚炎の検出方法
EP4253547A4 (en) 2020-11-30 2024-10-23 Kao Corporation Method for detecting severity of atopic dermatitis
JP7655720B2 (ja) * 2020-12-18 2025-04-02 花王株式会社 ストレスマーカー及びそれを用いた慢性ストレスレベルの検出方法
JP7655721B2 (ja) * 2020-12-18 2025-04-02 花王株式会社 疲労マーカー及びそれを用いた疲労の検出方法
CN116848265A (zh) * 2021-02-12 2023-10-03 花王株式会社 制备来自皮肤角质层的核酸试样的方法
WO2022220298A1 (ja) * 2021-04-15 2022-10-20 花王株式会社 乳幼児おむつ皮膚炎の症度の検出方法
US20240263225A1 (en) * 2021-05-31 2024-08-08 Kao Corporation Internal reference gene in skin surface lipid specimen
JP2023002298A (ja) * 2021-06-22 2023-01-10 花王株式会社 糖尿病指標値の検出方法
JP7750481B2 (ja) * 2021-06-22 2025-10-07 花王株式会社 内臓脂肪面積の検出方法
JP2023038883A (ja) * 2021-09-07 2023-03-17 花王株式会社 ＳＡＲＳ－ＣｏＶ－２の検出方法
NL2030378B1 (en) 2021-12-31 2023-07-05 Lumicks Ca Holding B V Selecting forces for means and methods involving cellular avidity
WO2024111617A1 (ja) 2022-11-24 2024-05-30 花王株式会社 皮膚表上脂質検体内部標準遺伝子
JP2025071065A (ja) * 2023-10-20 2025-05-02 花王株式会社 肌タイプの分類方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000009754A2 (en) 1998-08-14 2000-02-24 Johnson & Johnson Consumer Companies, Inc. HUMAN STEAROYL-CoA DESATURASE-RELATED COMPOSITIONS AND METHODS FOR TREATING SKIN DISORDERS
US20080226580A1 (en) 2007-03-13 2008-09-18 Riken Biodegradable oil absorbing film
JP2011019505A (ja) 2009-01-29 2011-02-03 Mukogawa Gakuin 特定遺伝子を検出する方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003533965A (ja) * 1998-08-14 2003-11-18 ジョンソン・アンド・ジョンソン・コンシューマー・カンパニーズ・インコーポレイテッド 皮膚の異常症状を治療するためのヒト・ステアロイル−ＣｏＡデサチュラーゼ−関連組成物および方法
US6645611B2 (en) * 2001-02-09 2003-11-11 3M Innovative Properties Company Dispensable oil absorbing skin wipes
US6638611B2 (en) * 2001-02-09 2003-10-28 3M Innovative Properties Company Multipurpose cosmetic wipes
US6649181B1 (en) * 2002-05-29 2003-11-18 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Cosmetic adhesive strip
JP2005192409A (ja) 2003-12-26 2005-07-21 Shiseido Co Ltd 体毛からｒｎａを抽出するための方法
CN104721883A (zh) 2004-03-17 2015-06-24 雷维维科公司 来源于缺乏任何功能性α1,3半乳糖基转移酶表达的动物的组织产品
US7183057B2 (en) 2004-03-31 2007-02-27 Dermtech International Tape stripping methods for analysis of skin disease and pathological skin state
KR101267430B1 (ko) 2006-10-04 2013-05-30 문우철 핵산을 안정적으로 보관하는 새로운 피부 유전자 카드와이를 이용한 유전자 분석방법, 그리고 이의 응용 방법
WO2009003654A2 (en) * 2007-06-29 2009-01-08 Medizinische Universität Innsbruck Selecting nucleic acid samples suitable for genotyping
BRPI0913578A2 (pt) 2008-05-14 2017-06-06 Dermtech Int diagnose de melanoma e lentigo solar por análise de ácido nucléico
JP2010115178A (ja) * 2008-11-14 2010-05-27 Nippon Menaade Keshohin Kk 皮膚の炎症の予測方法及びその用途
ES2818586T3 (es) 2011-02-07 2021-04-13 Governing Council Univ Toronto Biosondas y métodos de uso de las mismas
KR20140076543A (ko) 2011-06-07 2014-06-20 카리스 라이프 사이언스 룩셈부르크 홀딩스, 에스.에이.알.엘. 암에 대한 순환하는 생물지표들
US20140274789A1 (en) * 2011-08-11 2014-09-18 Andreas Keller Complex sets of mirnas as non-invasive biomarkers for psoriasis
CN104364394B (zh) 2012-03-17 2019-02-22 加州大学评议会 痤疮的快速诊断和个体化治疗
AU2013243948A1 (en) 2012-04-02 2014-10-30 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins associated with human disease
CA2868391A1 (en) 2012-04-02 2013-10-10 Stephane Bancel Polynucleotides comprising n1-methyl-pseudouridine and methods for preparing the same
JPWO2013179672A1 (ja) 2012-05-31 2016-01-18 武田薬品工業株式会社 子宮内膜症の判定方法
FR2993282B1 (fr) * 2012-07-13 2017-11-10 Expanscience Lab Procede d'identification de marqueurs moleculaires de la peau d'enfant
EP2922861A4 (en) * 2012-11-26 2016-09-14 Caris Life Sciences Switzerland Holdings Gmbh BIOMARKER COMPOSITIONS AND METHODS
CN114176586B (zh) 2012-12-14 2025-01-07 明德拉公司 用于检测和获取生物标志物的方法和装置
JP5895244B2 (ja) 2014-06-27 2016-03-30 株式会社ライラック研究所 機能性化粧水
JP6650240B2 (ja) 2014-11-25 2020-02-19 花王株式会社 メラニン制御剤の探索方法
WO2016172598A1 (en) 2015-04-22 2016-10-27 The Broad Institute Inc. Exosomes and uses thereof
US20160348189A1 (en) * 2015-05-28 2016-12-01 Lucigen Corporation Molecular detection of rna

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000009754A2 (en) 1998-08-14 2000-02-24 Johnson & Johnson Consumer Companies, Inc. HUMAN STEAROYL-CoA DESATURASE-RELATED COMPOSITIONS AND METHODS FOR TREATING SKIN DISORDERS
US20080226580A1 (en) 2007-03-13 2008-09-18 Riken Biodegradable oil absorbing film
JP2011019505A (ja) 2009-01-29 2011-02-03 Mukogawa Gakuin 特定遺伝子を検出する方法

Also Published As

Publication number Publication date
EP3372693A1 (en) 2018-09-12
EP3719138A1 (en) 2020-10-07
JP2018000206A (ja) 2018-01-11
EP3719138B1 (en) 2022-09-21
CN108699589B (zh) 2021-08-13
JP7323671B2 (ja) 2023-08-08
US11913061B2 (en) 2024-02-27
KR20180081624A (ko) 2018-07-16
EP3372693A4 (en) 2018-10-10
EP3372693B1 (en) 2020-02-12
JP2022097507A (ja) 2022-06-30
US20180371524A1 (en) 2018-12-27
WO2018008319A1 (ja) 2018-01-11
CN108699589A (zh) 2018-10-23

Similar Documents

Publication Publication Date Title
KR101961076B1 (ko) 핵산 시료의 조제 방법
JP7626515B2 (ja) 被験体の皮膚細胞に由来する核酸の調製方法
JP2020508689A (ja) 皮膚試料の収集および分析のための非侵襲的な方法
JP5311439B2 (ja) 皮膚の状態を評価する方法及びその用途
JP6943960B2 (ja) 乾燥の徴候を呈している皮膚を診断するための方法
EP3673270B1 (en) Diagnostic method of a skin showing signs of aging
JP6231252B1 (ja) 核酸試料の調製方法
JP5535571B2 (ja) 表皮ターンオーバーの評価方法及びその用途
JP2022097301A (ja) ストレスマーカー及びそれを用いた慢性ストレスレベルの検出方法
JP5275613B2 (ja) 皮膚のシミ形成を予測する皮膚検査方法
JP5693821B2 (ja) 皮膚のエストロゲン応答性を測定する方法、及び、シワ・タルミの形成、又はキメが粗くなるという皮膚老化の進行状態を予測する皮膚検査方法
JP2021117164A (ja) 皮膚炎症状態の評価方法
JP2023069413A (ja) 被膜の皮膚保湿効果の評価方法
JP7623827B2 (ja) 睡眠状態マーカー及びそれを用いた睡眠状態の検出方法
JP7712792B2 (ja) Ｒｎａ情報のデータ処理方法
JP2021175394A (ja) 月経周期マーカー
JP2025184029A (ja) 肌状態の推定方法、推定装置、推定プログラム、肌状態改善剤及び／又は美容手段の選択方法、肌状態を推定するためのマーカーを選択する方法
JP2023069499A (ja) 乾燥による皮膚表面形状悪化の検出方法
JP2025015487A (ja) 肌状態の推定方法、被験者に適した組成物及び／又は刺激の提案方法
JP2023075830A (ja) 皮膚外用製剤の有効性の評価方法
JP2011115098A (ja) 加齢による皮膚明度の低下を予測する皮膚評価方法
JP2022097303A (ja) 疲労マーカー及びそれを用いた疲労の検出方法
HK1194471B (en) Method for evaluating rough skin

Legal Events

Date Code Title Description
A201 Request for examination
A302 Request for accelerated examination
PA0105 International application

Patent event date: 20180629

Patent event code: PA01051R01D

Comment text: International Patent Application

PA0201 Request for examination
PA0302 Request for accelerated examination

Patent event date: 20180629

Patent event code: PA03022R01D

Comment text: Request for Accelerated Examination

PG1501 Laying open of application
E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20180927

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20190127

PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20190315

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20190315

End annual number: 3

Start annual number: 1

PG1601 Publication of registration
PR1001 Payment of annual fee

Payment date: 20220222

Start annual number: 4

End annual number: 4

PR1001 Payment of annual fee

Payment date: 20230222

Start annual number: 5

End annual number: 5

PR1001 Payment of annual fee

Payment date: 20240220

Start annual number: 6

End annual number: 6

PR1001 Payment of annual fee

Payment date: 20250218

Start annual number: 7

End annual number: 7