KR101782961B1 - 옥신돌 및 오르토-치환된 아닐린의 제조방법 및 합성 중간 생성물로서의 그의 용도 - Google Patents

옥신돌 및 오르토-치환된 아닐린의 제조방법 및 합성 중간 생성물로서의 그의 용도 Download PDF

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KR101782961B1
KR101782961B1 KR1020117028793A KR20117028793A KR101782961B1 KR 101782961 B1 KR101782961 B1 KR 101782961B1 KR 1020117028793 A KR1020117028793 A KR 1020117028793A KR 20117028793 A KR20117028793 A KR 20117028793A KR 101782961 B1 KR101782961 B1 KR 101782961B1
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alkyl
formula
compound
substituted
alkoxy
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KR20120016123A (ko
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마크 제임스 포드
군터 카리히
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바이엘 인텔렉쳐 프로퍼티 게엠베하
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020117028793A 2009-05-02 2010-04-27 옥신돌 및 오르토-치환된 아닐린의 제조방법 및 합성 중간 생성물로서의 그의 용도 Active KR101782961B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09006050A EP2246326A1 (de) 2009-05-02 2009-05-02 Verfahren zur Herstellung von Oxindolen und ortho-substituierten Anilinen und ihre Verwendung als Zwischenprodukte für Synthesen
EP09006050.0 2009-05-02
PCT/EP2010/002566 WO2010127786A1 (de) 2009-05-02 2010-04-27 Verfahren zur herstellung von oxindolen und ortho-substituierten anilinen und ihre verwendung als zwischenprodukte für synthesen

Related Child Applications (1)

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KR1020177016800A Division KR101862230B1 (ko) 2009-05-02 2010-04-27 옥신돌 및 오르토-치환된 아닐린의 제조방법 및 합성 중간 생성물로서의 그의 용도

Publications (2)

Publication Number Publication Date
KR20120016123A KR20120016123A (ko) 2012-02-22
KR101782961B1 true KR101782961B1 (ko) 2017-09-28

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KR1020117028793A Active KR101782961B1 (ko) 2009-05-02 2010-04-27 옥신돌 및 오르토-치환된 아닐린의 제조방법 및 합성 중간 생성물로서의 그의 용도
KR1020177016800A Active KR101862230B1 (ko) 2009-05-02 2010-04-27 옥신돌 및 오르토-치환된 아닐린의 제조방법 및 합성 중간 생성물로서의 그의 용도

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KR1020177016800A Active KR101862230B1 (ko) 2009-05-02 2010-04-27 옥신돌 및 오르토-치환된 아닐린의 제조방법 및 합성 중간 생성물로서의 그의 용도

Country Status (13)

Country Link
US (2) US8492590B2 (https=)
EP (2) EP2246326A1 (https=)
JP (1) JP5826167B2 (https=)
KR (2) KR101782961B1 (https=)
CN (1) CN102459163B (https=)
BR (1) BRPI1015123B1 (https=)
DK (1) DK2424835T3 (https=)
ES (1) ES2548024T3 (https=)
IL (1) IL216051A (https=)
MX (2) MX2011011547A (https=)
TW (1) TWI547473B (https=)
WO (1) WO2010127786A1 (https=)
ZA (1) ZA201108035B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008037631A1 (de) 2008-08-14 2010-02-18 Bayer Cropscience Ag Herbizid-Kombination mit Dimethoxytriazinyl-substituierten Difluormethansulfonylaniliden
WO2012028162A1 (de) * 2010-09-01 2012-03-08 Bayer Cropscience Ag Verfahren zur herstellung von oxindolen und ortho-substituierten anilinen und ihre verwendung als zwischenprodukte für synthesen
KR102057717B1 (ko) 2012-09-17 2019-12-19 바이엘 크롭사이언스 악티엔게젤샤프트 유동반응기에서 오르토 치환된 아닐린의 연속 제조방법
EP3049405A4 (en) 2013-09-26 2017-03-08 Pharmakea Inc. Autotaxin inhibitor compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002523400A (ja) * 1998-08-20 2002-07-30 住友製薬株式会社 オキシインドール誘導体

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3972894A (en) * 1973-04-27 1976-08-03 The Ohio State University Research Foundation Synthesis of oxindoles from anilines and β-thio carboxylic esters or amides
US4690943A (en) * 1984-09-19 1987-09-01 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds
US5663431A (en) * 1992-01-30 1997-09-02 Sanofi 1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present
FR2708605A1 (fr) 1993-07-30 1995-02-10 Sanofi Sa Dérivés du N-sulfonylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant.
DE19521355A1 (de) 1995-06-12 1996-12-19 Hoechst Schering Agrevo Gmbh Sulfonamide, Verfahren zu deren Herstellung und ihre Verwendung als Herbizide und Pflanzenwachstumsregulatoren
US7008940B1 (en) * 1999-08-20 2006-03-07 Takeda Pharmaceutical Company Limited Dihydrobenzofuran derivatives, process for the preparing thereof and agents
US6906096B2 (en) * 2002-06-28 2005-06-14 Irm Llc 4,7-Disubstituted indoles and methods of making
RU2006117635A (ru) * 2003-10-24 2007-12-10 Шеринг Акциенгезельшафт (De) Производные индолинона и их применение для лечения патологических состояний, таких как злокачественное новообразование
WO2005107466A1 (en) * 2004-05-12 2005-11-17 Bayer Cropscience Gmbh Plant growth regulation
US20080280891A1 (en) 2006-06-27 2008-11-13 Locus Pharmaceuticals, Inc. Anti-cancer agents and uses thereof
JP4770826B2 (ja) 2007-11-22 2011-09-14 大日本印刷株式会社 ２−オキシインドール誘導体の製造法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002523400A (ja) * 1998-08-20 2002-07-30 住友製薬株式会社 オキシインドール誘導体

Also Published As

Publication number Publication date
WO2010127786A8 (de) 2011-11-10
US20110118478A1 (en) 2011-05-19
IL216051A (en) 2015-03-31
MX2011011547A (es) 2011-11-29
CN102459163B (zh) 2015-05-13
US20130281711A1 (en) 2013-10-24
US8492590B2 (en) 2013-07-23
US9242934B2 (en) 2016-01-26
EP2424835A1 (de) 2012-03-07
ZA201108035B (en) 2013-01-30
IL216051A0 (en) 2012-01-31
BRPI1015123A2 (pt) 2019-04-09
WO2010127786A1 (de) 2010-11-11
KR101862230B1 (ko) 2018-05-29
KR20120016123A (ko) 2012-02-22
JP5826167B2 (ja) 2015-12-02
EP2424835B1 (de) 2015-07-01
TWI547473B (zh) 2016-09-01
EP2246326A1 (de) 2010-11-03
ES2548024T3 (es) 2015-10-13
TW201111331A (en) 2011-04-01
DK2424835T3 (en) 2015-10-05
MX367426B (es) 2019-08-21
BRPI1015123B1 (pt) 2021-05-04
CN102459163A (zh) 2012-05-16
JP2012526045A (ja) 2012-10-25
KR20170073738A (ko) 2017-06-28

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