IL216051A - Methods for Making Ortho-Ortho-Converted Anilines and Using Them as Intermediates in Synthesis - Google Patents

Methods for Making Ortho-Ortho-Converted Anilines and Using Them as Intermediates in Synthesis

Info

Publication number
IL216051A
IL216051A IL216051A IL21605111A IL216051A IL 216051 A IL216051 A IL 216051A IL 216051 A IL216051 A IL 216051A IL 21605111 A IL21605111 A IL 21605111A IL 216051 A IL216051 A IL 216051A
Authority
IL
Israel
Prior art keywords
syntheses
ortho
intermediate products
substituted anilines
producing oxindoles
Prior art date
Application number
IL216051A
Other languages
English (en)
Hebrew (he)
Other versions
IL216051A0 (en
Inventor
Mark James Ford
Gunter Karig
Original Assignee
Mark James Ford
Gunter Karig
Bayer Ip Gmbh
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mark James Ford, Gunter Karig, Bayer Ip Gmbh, Bayer Cropscience Ag filed Critical Mark James Ford
Publication of IL216051A0 publication Critical patent/IL216051A0/en
Publication of IL216051A publication Critical patent/IL216051A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26Separation; Purification; Stabilisation; Use of additives
    • C07C319/28Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL216051A 2009-05-02 2011-10-30 Methods for Making Ortho-Ortho-Converted Anilines and Using Them as Intermediates in Synthesis IL216051A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09006050A EP2246326A1 (de) 2009-05-02 2009-05-02 Verfahren zur Herstellung von Oxindolen und ortho-substituierten Anilinen und ihre Verwendung als Zwischenprodukte für Synthesen
PCT/EP2010/002566 WO2010127786A1 (de) 2009-05-02 2010-04-27 Verfahren zur herstellung von oxindolen und ortho-substituierten anilinen und ihre verwendung als zwischenprodukte für synthesen

Publications (2)

Publication Number Publication Date
IL216051A0 IL216051A0 (en) 2012-01-31
IL216051A true IL216051A (en) 2015-03-31

Family

ID=41050783

Family Applications (1)

Application Number Title Priority Date Filing Date
IL216051A IL216051A (en) 2009-05-02 2011-10-30 Methods for Making Ortho-Ortho-Converted Anilines and Using Them as Intermediates in Synthesis

Country Status (13)

Country Link
US (2) US8492590B2 (https=)
EP (2) EP2246326A1 (https=)
JP (1) JP5826167B2 (https=)
KR (2) KR101782961B1 (https=)
CN (1) CN102459163B (https=)
BR (1) BRPI1015123B1 (https=)
DK (1) DK2424835T3 (https=)
ES (1) ES2548024T3 (https=)
IL (1) IL216051A (https=)
MX (2) MX2011011547A (https=)
TW (1) TWI547473B (https=)
WO (1) WO2010127786A1 (https=)
ZA (1) ZA201108035B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008037631A1 (de) 2008-08-14 2010-02-18 Bayer Cropscience Ag Herbizid-Kombination mit Dimethoxytriazinyl-substituierten Difluormethansulfonylaniliden
WO2012028162A1 (de) * 2010-09-01 2012-03-08 Bayer Cropscience Ag Verfahren zur herstellung von oxindolen und ortho-substituierten anilinen und ihre verwendung als zwischenprodukte für synthesen
KR102057717B1 (ko) 2012-09-17 2019-12-19 바이엘 크롭사이언스 악티엔게젤샤프트 유동반응기에서 오르토 치환된 아닐린의 연속 제조방법
EP3049405A4 (en) 2013-09-26 2017-03-08 Pharmakea Inc. Autotaxin inhibitor compounds

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3972894A (en) * 1973-04-27 1976-08-03 The Ohio State University Research Foundation Synthesis of oxindoles from anilines and β-thio carboxylic esters or amides
US4690943A (en) * 1984-09-19 1987-09-01 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds
US5663431A (en) * 1992-01-30 1997-09-02 Sanofi 1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present
FR2708605A1 (fr) 1993-07-30 1995-02-10 Sanofi Sa Dérivés du N-sulfonylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant.
DE19521355A1 (de) 1995-06-12 1996-12-19 Hoechst Schering Agrevo Gmbh Sulfonamide, Verfahren zu deren Herstellung und ihre Verwendung als Herbizide und Pflanzenwachstumsregulatoren
CA2340701C (en) * 1998-08-20 2009-05-26 Sumitomo Pharmaceuticals Co., Ltd. Oxindole derivatives as growth hormone releasers
US7008940B1 (en) * 1999-08-20 2006-03-07 Takeda Pharmaceutical Company Limited Dihydrobenzofuran derivatives, process for the preparing thereof and agents
US6906096B2 (en) * 2002-06-28 2005-06-14 Irm Llc 4,7-Disubstituted indoles and methods of making
RU2006117635A (ru) * 2003-10-24 2007-12-10 Шеринг Акциенгезельшафт (De) Производные индолинона и их применение для лечения патологических состояний, таких как злокачественное новообразование
WO2005107466A1 (en) * 2004-05-12 2005-11-17 Bayer Cropscience Gmbh Plant growth regulation
US20080280891A1 (en) 2006-06-27 2008-11-13 Locus Pharmaceuticals, Inc. Anti-cancer agents and uses thereof
JP4770826B2 (ja) 2007-11-22 2011-09-14 大日本印刷株式会社 2−オキシインドール誘導体の製造法

Also Published As

Publication number Publication date
KR101782961B1 (ko) 2017-09-28
WO2010127786A8 (de) 2011-11-10
US20110118478A1 (en) 2011-05-19
MX2011011547A (es) 2011-11-29
CN102459163B (zh) 2015-05-13
US20130281711A1 (en) 2013-10-24
US8492590B2 (en) 2013-07-23
US9242934B2 (en) 2016-01-26
EP2424835A1 (de) 2012-03-07
ZA201108035B (en) 2013-01-30
IL216051A0 (en) 2012-01-31
BRPI1015123A2 (pt) 2019-04-09
WO2010127786A1 (de) 2010-11-11
KR101862230B1 (ko) 2018-05-29
KR20120016123A (ko) 2012-02-22
JP5826167B2 (ja) 2015-12-02
EP2424835B1 (de) 2015-07-01
TWI547473B (zh) 2016-09-01
EP2246326A1 (de) 2010-11-03
ES2548024T3 (es) 2015-10-13
TW201111331A (en) 2011-04-01
DK2424835T3 (en) 2015-10-05
MX367426B (es) 2019-08-21
BRPI1015123B1 (pt) 2021-05-04
CN102459163A (zh) 2012-05-16
JP2012526045A (ja) 2012-10-25
KR20170073738A (ko) 2017-06-28

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