KR101762295B1 - 생체시료의 자동 분석 장치 및 방법 - Google Patents
생체시료의 자동 분석 장치 및 방법 Download PDFInfo
- Publication number
- KR101762295B1 KR101762295B1 KR1020120013757A KR20120013757A KR101762295B1 KR 101762295 B1 KR101762295 B1 KR 101762295B1 KR 1020120013757 A KR1020120013757 A KR 1020120013757A KR 20120013757 A KR20120013757 A KR 20120013757A KR 101762295 B1 KR101762295 B1 KR 101762295B1
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- South Korea
- Prior art keywords
- unit
- pipette
- amplification
- nucleic acid
- electrophoresis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/12—Apparatus for enzymology or microbiology with sterilisation, filtration or dialysis means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/36—Apparatus for enzymology or microbiology including condition or time responsive control, e.g. automatically controlled fermentors
- C12M1/38—Temperature-responsive control
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
- C12M35/08—Chemical, biochemical or biological means, e.g. plasma jet, co-culture
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/10—Detection mode being characterised by the assay principle
- C12Q2565/125—Electrophoretic separation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Robotics (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Physiology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020120013757A KR101762295B1 (ko) | 2012-02-10 | 2012-02-10 | 생체시료의 자동 분석 장치 및 방법 |
| EP13746518.3A EP2813579B1 (en) | 2012-02-10 | 2013-02-07 | Apparatus and method for automatically analyzing biological samples |
| BR112014019798-9A BR112014019798B1 (pt) | 2012-02-10 | 2013-02-07 | Aparelho e método para automaticamente analisar amostras biológicas |
| JP2014556475A JP5908613B2 (ja) | 2012-02-10 | 2013-02-07 | 生体試料の自動分析装置及び方法 |
| US14/377,537 US9765383B2 (en) | 2012-02-10 | 2013-02-07 | Apparatus and method for automatically analyzing biological samples |
| IN1572MUN2014 IN2014MN01572A (enExample) | 2012-02-10 | 2013-02-07 | |
| RU2014136713A RU2610687C2 (ru) | 2012-02-10 | 2013-02-07 | Устройство и способ для автоматического анализа биологических образцов |
| CA2864260A CA2864260C (en) | 2012-02-10 | 2013-02-07 | Apparatus and method for automatically analyzing biological samples |
| CN201380018553.3A CN104204229B (zh) | 2012-02-10 | 2013-02-07 | 用于自动分析生物试样的设备以及方法 |
| AU2013218402A AU2013218402B2 (en) | 2012-02-10 | 2013-02-07 | Apparatus and method for automatically analyzing biological samples |
| PCT/KR2013/000985 WO2013119049A1 (ko) | 2012-02-10 | 2013-02-07 | 생물학적 시료의 자동 분석 장치 및 방법 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020120013757A KR101762295B1 (ko) | 2012-02-10 | 2012-02-10 | 생체시료의 자동 분석 장치 및 방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20130092185A KR20130092185A (ko) | 2013-08-20 |
| KR101762295B1 true KR101762295B1 (ko) | 2017-08-04 |
Family
ID=48947758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020120013757A Expired - Fee Related KR101762295B1 (ko) | 2012-02-10 | 2012-02-10 | 생체시료의 자동 분석 장치 및 방법 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9765383B2 (enExample) |
| EP (1) | EP2813579B1 (enExample) |
| JP (1) | JP5908613B2 (enExample) |
| KR (1) | KR101762295B1 (enExample) |
| CN (1) | CN104204229B (enExample) |
| AU (1) | AU2013218402B2 (enExample) |
| BR (1) | BR112014019798B1 (enExample) |
| CA (1) | CA2864260C (enExample) |
| IN (1) | IN2014MN01572A (enExample) |
| RU (1) | RU2610687C2 (enExample) |
| WO (1) | WO2013119049A1 (enExample) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20200118979A (ko) * | 2019-04-09 | 2020-10-19 | 주식회사 케이엠씨로보틱스 | 시료 분석용 전처리 자동화 장치 |
| KR20210155460A (ko) * | 2020-06-16 | 2021-12-23 | 주식회사 에이아이바이오틱스 | Rt-pcr 디바이스 |
| KR20220009548A (ko) * | 2020-07-16 | 2022-01-25 | 주식회사 에이아이바이오틱스 | 올인원 rt-pcr 장치 |
| WO2022080970A1 (en) * | 2020-10-15 | 2022-04-21 | Seegene, Inc. | Solution mixing device and solution mixing method |
| KR20220148636A (ko) * | 2021-04-29 | 2022-11-07 | 주식회사 제놀루션 | 핵산추출장치 및 핵산추출장치에 사용되는 캡 |
| KR20230171093A (ko) * | 2022-06-13 | 2023-12-20 | (주)옵토레인 | 검체 처리 장치 |
| WO2024181638A1 (ko) * | 2023-02-28 | 2024-09-06 | (주)한국바이오셀프 | 액체생검을 위한 인체유래 물질 추출 자동화 기기 및 이를 이용한 인체유래 물질 추출 방법 |
Families Citing this family (97)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10072927B2 (en) | 2016-01-07 | 2018-09-11 | Rarecyte, Inc. | Detecting a substrate |
| CN203866294U (zh) * | 2013-11-01 | 2014-10-08 | 艾康生物技术(杭州)有限公司 | 核酸提取仪 |
| WO2015072757A1 (ko) * | 2013-11-15 | 2015-05-21 | 바디텍메드 주식회사 | 일체화된 반응 및 검출 수단을 구비한 시험 장치에 사용되는 스테이션 |
| KR101653302B1 (ko) * | 2014-02-26 | 2016-09-01 | (주)한울티피씨 | 핵산추출장치 |
| KR102344395B1 (ko) * | 2014-06-24 | 2021-12-29 | (주)바이오니아 | 자성 입자를 이용한 핵산 분리 방법 |
| KR101686049B1 (ko) * | 2014-10-15 | 2016-12-13 | 주식회사 노블바이오 | 유전자 정제 방법 및 그 장치 |
| WO2016117726A1 (en) * | 2015-01-23 | 2016-07-28 | Infopia Co., Ltd. | Cartridge |
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| KR101707987B1 (ko) * | 2015-06-16 | 2017-02-21 | 휴스텝스 주식회사 | 자동 정량 분주기 및 상기 분주기를 포함하는 연속식 유전자 추출-증폭 장비와 연속식 유전자 추출-증폭 방법 |
| JP2018529942A (ja) * | 2015-08-10 | 2018-10-11 | カウンシル,インコーポレーテッド | モジュール式液体取り扱いシステム |
| CN106701527A (zh) * | 2015-08-11 | 2017-05-24 | 广州康昕瑞基因健康科技有限公司 | 一种试剂工作站 |
| CN105085719B (zh) * | 2015-09-09 | 2017-03-22 | 中国科学院华南植物园 | 聚合箱 |
| CN105400680B (zh) * | 2015-12-11 | 2017-12-15 | 舟山医院 | 一种荧光定量pcr仪 |
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| WO2017131254A1 (ko) * | 2016-01-28 | 2017-08-03 | (주)바이오필리아 | 유전자 또는 생물학적 물질의 분리 및 검사 키트 |
| CN105624032B (zh) * | 2016-02-25 | 2017-11-28 | 东南大学 | 一种病原体现场快速检测系统 |
| EP3213819B1 (en) * | 2016-03-02 | 2021-09-29 | F. Hoffmann-La Roche AG | Device and method for separation |
| JP6466027B2 (ja) * | 2016-04-20 | 2019-02-13 | シスメックス株式会社 | 核酸分析装置 |
| CN105969899A (zh) * | 2016-07-19 | 2016-09-28 | 湖州高亿诺生物科技有限公司 | 基于多孔板的痕量靶标核酸的富集方法和装置 |
| WO2018017768A1 (en) * | 2016-07-21 | 2018-01-25 | Siemens Healthcare Diagnostics Inc. | Mechanism for storage of refrigerated calibration and quality control material |
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| KR101866195B1 (ko) * | 2016-08-26 | 2018-06-12 | (주)에스엠션전자 | 휴대용 핵산 증폭장치 및 이를 이용한 핵산 증폭방법 |
| CN106367307A (zh) * | 2016-08-30 | 2017-02-01 | 冯晓均 | 一种自动化核酸定量分析装置及分析方法 |
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| KR102022054B1 (ko) * | 2017-08-29 | 2019-09-18 | 신진메딕스(주) | 시약 공급이 용이한 자동분주기 |
| KR102022060B1 (ko) * | 2017-08-29 | 2019-09-19 | 신진메딕스(주) | 카트리지의 자동공급이 가능한 감마카운터 |
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Also Published As
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| CN104204229B (zh) | 2016-09-07 |
| CA2864260C (en) | 2018-05-01 |
| WO2013119049A1 (ko) | 2013-08-15 |
| EP2813579B1 (en) | 2017-04-05 |
| AU2013218402A1 (en) | 2014-09-04 |
| KR20130092185A (ko) | 2013-08-20 |
| BR112014019798A2 (pt) | 2021-06-01 |
| RU2610687C2 (ru) | 2017-02-14 |
| BR112014019798B1 (pt) | 2022-03-03 |
| US20150037803A1 (en) | 2015-02-05 |
| IN2014MN01572A (enExample) | 2015-05-08 |
| JP5908613B2 (ja) | 2016-04-26 |
| RU2014136713A (ru) | 2016-04-10 |
| CA2864260A1 (en) | 2013-08-15 |
| JP2015506710A (ja) | 2015-03-05 |
| US9765383B2 (en) | 2017-09-19 |
| CN104204229A (zh) | 2014-12-10 |
| AU2013218402B2 (en) | 2016-07-07 |
| EP2813579A1 (en) | 2014-12-17 |
| EP2813579A4 (en) | 2015-09-16 |
| BR112014019798A8 (pt) | 2017-07-11 |
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