KR101661952B1 - 극저점도의 신규한 에스테르화된 셀룰로스 에테르 - Google Patents

극저점도의 신규한 에스테르화된 셀룰로스 에테르 Download PDF

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Publication number
KR101661952B1
KR101661952B1 KR1020157026855A KR20157026855A KR101661952B1 KR 101661952 B1 KR101661952 B1 KR 101661952B1 KR 1020157026855 A KR1020157026855 A KR 1020157026855A KR 20157026855 A KR20157026855 A KR 20157026855A KR 101661952 B1 KR101661952 B1 KR 101661952B1
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KR
South Korea
Prior art keywords
esterified cellulose
cellulose ether
viscosity
esterified
mpa
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KR1020157026855A
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English (en)
Korean (ko)
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KR20150119472A (ko
Inventor
올리버 페터만
로버트 비. 아펠
마이놀프 브락하겐
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다우 글로벌 테크놀로지스 엘엘씨
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    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B13/00Preparation of cellulose ether-esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B11/00Preparation of cellulose ethers
    • C08B11/20Post-etherification treatments of chemical or physical type, e.g. mixed etherification in two steps, including purification
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020157026855A 2013-03-07 2014-02-28 극저점도의 신규한 에스테르화된 셀룰로스 에테르 Expired - Fee Related KR101661952B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361774161P 2013-03-07 2013-03-07
US61/774,161 2013-03-07
PCT/US2014/019266 WO2014137778A1 (en) 2013-03-07 2014-02-28 Novel esterified cellulose ethers of very low viscosity

Publications (2)

Publication Number Publication Date
KR20150119472A KR20150119472A (ko) 2015-10-23
KR101661952B1 true KR101661952B1 (ko) 2016-10-04

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157026855A Expired - Fee Related KR101661952B1 (ko) 2013-03-07 2014-02-28 극저점도의 신규한 에스테르화된 셀룰로스 에테르

Country Status (7)

Country Link
US (1) US9617351B2 (https=)
EP (1) EP2964204B1 (https=)
JP (1) JP6267239B2 (https=)
KR (1) KR101661952B1 (https=)
CN (1) CN105025887B (https=)
BR (1) BR112015015846A2 (https=)
WO (1) WO2014137778A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6356922B2 (ja) * 2015-03-16 2018-07-11 ダウ グローバル テクノロジーズ エルエルシー 低い中和度を有する水溶性エステル化セルロースエーテル
US20180030157A1 (en) * 2015-03-16 2018-02-01 Dow Global Technologies Llc Process for fractionating an esterified cellulose ether
KR20170128350A (ko) * 2015-03-16 2017-11-22 다우 글로벌 테크놀로지스 엘엘씨 에스테르화된 셀룰로오스 에테르의 수용액
EP3270970B1 (en) 2015-03-16 2019-01-09 Dow Global Technologies LLC Gelling esterified cellulose ethers
BR112017018232A2 (pt) 2015-03-16 2018-04-17 Dow Global Technologies Llc éteres de celulose esterificados solúveis em água
KR20170128349A (ko) * 2015-03-16 2017-11-22 다우 글로벌 테크놀로지스 엘엘씨 지방족 카복실산의 존재하에서의 에스테르화된 셀룰로오스 에테르의 제조 방법
KR20190013815A (ko) * 2016-05-25 2019-02-11 다우 글로벌 테크놀로지스 엘엘씨 셀룰로스 에터 아세테이트의 수용액
KR102490265B1 (ko) * 2016-11-02 2023-01-20 신에쓰 가가꾸 고교 가부시끼가이샤 히프로멜로오스아세트산에스테르숙신산에스테르 및 제조 방법
WO2018170083A1 (en) 2017-03-17 2018-09-20 Dow Global Technologies Llc Process for recovering an esterified cellulose ether from a reaction product mixture
CN110366566B (zh) 2017-03-17 2021-08-13 陶氏环球技术有限责任公司 用于从反应产物混合物中回收酯化纤维素醚的方法
JP2020511572A (ja) 2017-03-17 2020-04-16 ダウ グローバル テクノロジーズ エルエルシー 反応生成物混合物からのエステル化セルロースエーテルの回収方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040242862A1 (en) * 2001-08-25 2004-12-02 Alf Hammes Method for producing a cellulose ether of low viscosity by means of acid oxidative decomposition of ground and dried cellulose ethers
JP2008501009A (ja) * 2004-05-28 2008-01-17 ファイザー・プロダクツ・インク 性能を高めた医薬組成物

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4819231B1 (https=) * 1970-03-06 1973-06-12
US4226981A (en) * 1977-09-28 1980-10-07 Shin-Etsu Chemical Co., Ltd. Ether-ester derivatives of cellulose and their applications
US4365060A (en) 1979-04-28 1982-12-21 Shin-Etsu Chemical Co. Ltd. Enterosoluble capsules
JPS59167521A (ja) * 1983-03-14 1984-09-21 Shin Etsu Chem Co Ltd 腸溶性コ−テイング剤組成物
JPS6281402A (ja) * 1985-10-07 1987-04-14 Shin Etsu Chem Co Ltd セルロ−スエ−テル酸性ジカルボン酸エステルの製造方法
JP3149122B2 (ja) 1994-11-07 2001-03-26 信越化学工業株式会社 固形腸溶製剤のコーティング用基剤
JPH10167959A (ja) * 1996-12-04 1998-06-23 Zensei Yakuhin Kogyo Kk ジクロフェナクナトリウムの徐放性カプセル製剤
EP0872233A1 (en) 1997-04-14 1998-10-21 Janssen Pharmaceutica N.V. Antiretroviral compositions with improved bioavailability
ES2287971T3 (es) 1997-08-11 2007-12-16 Pfizer Products Inc. Dispersiones farmaceuticas solidas con biodisponibilidad incrementada.
KR100387126B1 (ko) * 2001-04-19 2003-06-12 삼성정밀화학 주식회사 히드록시프로필메틸 셀룰로오스 프탈레이트의 분리정제방법
IL165043A0 (en) 2002-05-17 2005-12-18 Tibotec Pharm Ltd broadspectrum substituted benzisoxazole sulfonamide hiv protease inhibitors
EP1530457B1 (en) 2002-08-12 2009-09-09 Bend Research, Inc. Pharmaceutical compositions of drugs in semi-ordered form and polymers
US8920553B2 (en) 2007-11-09 2014-12-30 Dow Global Technologies Llc Cellulose ether coating compositions and method
MX2010004931A (es) * 2007-11-09 2010-06-11 Union Carbide Chem Plastic Metodo para preparar eter de celulosa de muy baja viscosidad y producto.
US8569364B2 (en) * 2007-11-28 2013-10-29 Sequoia Pharmaceuticals, Inc. 5-substituted benzofurans as inhibitors of cytochrome P450 2D6
JP5322740B2 (ja) 2009-04-01 2013-10-23 国立大学法人東京農工大学 有害生物防除方法
JP5792807B2 (ja) 2010-06-14 2015-10-14 ダウ グローバル テクノロジーズ エルエルシー アセテートおよびサクシネートの置換が向上されたヒドロキシプロピルメチルセルロースアセテートサクシネート
US20120251588A1 (en) * 2011-03-30 2012-10-04 Miyuki Fukasawa Coating Composition, Solid Preparation Coated Therewith, and Method for Preparing Solid Preparation
WO2013148154A1 (en) 2012-03-27 2013-10-03 Dow Global Technologies Llc A process of preparing an ester of a cellulose ether
CN104427979B (zh) 2012-04-11 2018-02-16 陶氏环球技术有限责任公司 具有特定的取代基分布的酯化的纤维素醚
KR102138546B1 (ko) * 2012-08-24 2020-07-28 다우 글로벌 테크놀로지스 엘엘씨 부분적으로 가교결합된 에스테르화된 셀룰로즈 에테르
MX374548B (es) * 2012-08-24 2025-03-06 Dow Global Technologies Llc Eteres de celulosa esterificados novedosos de alto peso molecular y homogeneidad.
MX2015002430A (es) * 2012-08-24 2015-06-22 Dow Global Technologies Llc Acetato-succinatos de hidroxialquilmetilcelulosa.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040242862A1 (en) * 2001-08-25 2004-12-02 Alf Hammes Method for producing a cellulose ether of low viscosity by means of acid oxidative decomposition of ground and dried cellulose ethers
JP2008501009A (ja) * 2004-05-28 2008-01-17 ファイザー・プロダクツ・インク 性能を高めた医薬組成物

Also Published As

Publication number Publication date
JP6267239B2 (ja) 2018-01-24
WO2014137778A1 (en) 2014-09-12
CN105025887A (zh) 2015-11-04
JP2016516835A (ja) 2016-06-09
KR20150119472A (ko) 2015-10-23
US9617351B2 (en) 2017-04-11
EP2964204A1 (en) 2016-01-13
US20150376299A1 (en) 2015-12-31
CN105025887B (zh) 2017-07-28
EP2964204B1 (en) 2017-01-04
BR112015015846A2 (pt) 2017-07-11

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