CN105025887B - 新颖极低粘度酯化纤维素醚 - Google Patents

新颖极低粘度酯化纤维素醚 Download PDF

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Publication number
CN105025887B
CN105025887B CN201480011014.1A CN201480011014A CN105025887B CN 105025887 B CN105025887 B CN 105025887B CN 201480011014 A CN201480011014 A CN 201480011014A CN 105025887 B CN105025887 B CN 105025887B
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China
Prior art keywords
cellulose ether
esterified cellulose
viscosity
mpa
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN201480011014.1A
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English (en)
Chinese (zh)
Other versions
CN105025887A (zh
Inventor
O·彼得曼
R·B·阿佩尔
M·布拉克哈根
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Dow Global Technologies LLC
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Dow Global Technologies LLC
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Publication of CN105025887A publication Critical patent/CN105025887A/zh
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B13/00—Preparation of cellulose ether-esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B11/00—Preparation of cellulose ethers
    • C08B11/20—Post-etherification treatments of chemical or physical type, e.g. mixed etherification in two steps, including purification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201480011014.1A 2013-03-07 2014-02-28 新颖极低粘度酯化纤维素醚 Expired - Fee Related CN105025887B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361774161P 2013-03-07 2013-03-07
US61/774161 2013-03-07
PCT/US2014/019266 WO2014137778A1 (en) 2013-03-07 2014-02-28 Novel esterified cellulose ethers of very low viscosity

Publications (2)

Publication Number Publication Date
CN105025887A CN105025887A (zh) 2015-11-04
CN105025887B true CN105025887B (zh) 2017-07-28

Family

ID=50439471

Family Applications (1)

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CN201480011014.1A Expired - Fee Related CN105025887B (zh) 2013-03-07 2014-02-28 新颖极低粘度酯化纤维素醚

Country Status (7)

Country Link
US (1) US9617351B2 (https=)
EP (1) EP2964204B1 (https=)
JP (1) JP6267239B2 (https=)
KR (1) KR101661952B1 (https=)
CN (1) CN105025887B (https=)
BR (1) BR112015015846A2 (https=)
WO (1) WO2014137778A1 (https=)

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KR20170128349A (ko) * 2015-03-16 2017-11-22 다우 글로벌 테크놀로지스 엘엘씨 지방족 카복실산의 존재하에서의 에스테르화된 셀룰로오스 에테르의 제조 방법
WO2016148975A1 (en) * 2015-03-16 2016-09-22 Dow Global Technologies Llc A process for fractionating an esterified cellulose ether
US10377835B2 (en) 2015-03-16 2019-08-13 Dow Global Technologies Llc Water-soluble esterified cellulose ethers
US10214594B2 (en) 2015-03-16 2019-02-26 Dow Global Technologies Llc Water-soluble esterified cellulose ethers having a low degree of neutralization
EP3270970B1 (en) 2015-03-16 2019-01-09 Dow Global Technologies LLC Gelling esterified cellulose ethers
JP6564148B2 (ja) * 2016-05-25 2019-08-21 ダウ グローバル テクノロジーズ エルエルシー セルロースエーテルアセテートの水溶液
US10888525B2 (en) * 2016-11-02 2021-01-12 Shin-Etsu Chemical Co., Ltd. Hypromellose acetate succinate and method for producing the same
KR20190126318A (ko) 2017-03-17 2019-11-11 다우 글로벌 테크놀로지스 엘엘씨 반응 생성 혼합물로부터 에스테르화 셀룰로스 에테르를 회수하는 공정
US20210115161A1 (en) 2017-03-17 2021-04-22 Dow Global Technologies Llc Process for Recovering an Esterified Cellulose Ether from a Reaction Product Mixture
WO2018170083A1 (en) 2017-03-17 2018-09-20 Dow Global Technologies Llc Process for recovering an esterified cellulose ether from a reaction product mixture

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226981A (en) * 1977-09-28 1980-10-07 Shin-Etsu Chemical Co., Ltd. Ether-ester derivatives of cellulose and their applications
EP0219426A2 (en) * 1985-10-07 1987-04-22 Shin-Etsu Chemical Co., Ltd. A method for the preparation of an acidic dicarboxylic acid ester of cellulose ether

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KR101019648B1 (ko) * 2002-05-17 2011-03-07 티보텍 파마슈티컬즈 광범위 스펙트럼의 치환된 벤즈이속사졸 설폰아미드ｈｉｖ 프로테아제 저해제
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KR102041766B1 (ko) 2012-03-27 2019-11-07 다우 글로벌 테크놀로지스 엘엘씨 셀룰로스 에테르의 에스테르의 제조방법
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Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226981A (en) * 1977-09-28 1980-10-07 Shin-Etsu Chemical Co., Ltd. Ether-ester derivatives of cellulose and their applications
EP0219426A2 (en) * 1985-10-07 1987-04-22 Shin-Etsu Chemical Co., Ltd. A method for the preparation of an acidic dicarboxylic acid ester of cellulose ether

Also Published As

Publication number Publication date
CN105025887A (zh) 2015-11-04
JP6267239B2 (ja) 2018-01-24
US20150376299A1 (en) 2015-12-31
US9617351B2 (en) 2017-04-11
EP2964204A1 (en) 2016-01-13
KR101661952B1 (ko) 2016-10-04
JP2016516835A (ja) 2016-06-09
KR20150119472A (ko) 2015-10-23
WO2014137778A1 (en) 2014-09-12
EP2964204B1 (en) 2017-01-04
BR112015015846A2 (pt) 2017-07-11

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Granted publication date: 20170728

Termination date: 20200228