KR101661952B1 - 극저점도의 신규한 에스테르화된 셀룰로스 에테르 - Google Patents

극저점도의 신규한 에스테르화된 셀룰로스 에테르 Download PDF

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Publication number
KR101661952B1
KR101661952B1 KR1020157026855A KR20157026855A KR101661952B1 KR 101661952 B1 KR101661952 B1 KR 101661952B1 KR 1020157026855 A KR1020157026855 A KR 1020157026855A KR 20157026855 A KR20157026855 A KR 20157026855A KR 101661952 B1 KR101661952 B1 KR 101661952B1
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KR
South Korea
Prior art keywords
esterified cellulose
cellulose ether
viscosity
esterified
mpa
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KR1020157026855A
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English (en)
Korean (ko)
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KR20150119472A (ko
Inventor
올리버 페터만
로버트 비. 아펠
마이놀프 브락하겐
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다우 글로벌 테크놀로지스 엘엘씨
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B13/00—Preparation of cellulose ether-esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B11/00—Preparation of cellulose ethers
    • C08B11/20—Post-etherification treatments of chemical or physical type, e.g. mixed etherification in two steps, including purification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020157026855A 2013-03-07 2014-02-28 극저점도의 신규한 에스테르화된 셀룰로스 에테르 Expired - Fee Related KR101661952B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361774161P 2013-03-07 2013-03-07
US61/774,161 2013-03-07
PCT/US2014/019266 WO2014137778A1 (en) 2013-03-07 2014-02-28 Novel esterified cellulose ethers of very low viscosity

Publications (2)

Publication Number Publication Date
KR20150119472A KR20150119472A (ko) 2015-10-23
KR101661952B1 true KR101661952B1 (ko) 2016-10-04

Family

ID=50439471

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157026855A Expired - Fee Related KR101661952B1 (ko) 2013-03-07 2014-02-28 극저점도의 신규한 에스테르화된 셀룰로스 에테르

Country Status (7)

Country Link
US (1) US9617351B2 (enExample)
EP (1) EP2964204B1 (enExample)
JP (1) JP6267239B2 (enExample)
KR (1) KR101661952B1 (enExample)
CN (1) CN105025887B (enExample)
BR (1) BR112015015846A2 (enExample)
WO (1) WO2014137778A1 (enExample)

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US10377835B2 (en) 2015-03-16 2019-08-13 Dow Global Technologies Llc Water-soluble esterified cellulose ethers
JP6295380B2 (ja) * 2015-03-16 2018-03-14 ダウ グローバル テクノロジーズ エルエルシー 脂肪族カルボン酸の存在下でエステル化セルロースエーテルを調製するためのプロセス
JP6749929B2 (ja) * 2015-03-16 2020-09-02 ダウ グローバル テクノロジーズ エルエルシー エステル化セルロースエーテルを分画するためのプロセス
EP3270973B1 (en) * 2015-03-16 2019-01-09 Dow Global Technologies LLC Aqueous solution of an esterified cellulose ether
EP3270971B1 (en) 2015-03-16 2019-01-09 Dow Global Technologies LLC Water-soluble esterified cellulose ethers having a low degree of neutralization
CN107406522B (zh) * 2015-03-16 2019-02-26 陶氏环球技术有限责任公司 酯化纤维素醚的凝胶化
EP3463314B1 (en) * 2016-05-25 2020-07-22 Dow Global Technologies LLC Aqueous solution of cellulose ether acetate
KR102490265B1 (ko) * 2016-11-02 2023-01-20 신에쓰 가가꾸 고교 가부시끼가이샤 히프로멜로오스아세트산에스테르숙신산에스테르 및 제조 방법
MX2019010207A (es) 2017-03-17 2019-10-09 Dow Global Technologies Llc Proceso para recuperar un eter de celulosa esterificado a partir de una mezcla de producto de reaccion.
JP2020511572A (ja) * 2017-03-17 2020-04-16 ダウ グローバル テクノロジーズ エルエルシー 反応生成物混合物からのエステル化セルロースエーテルの回収方法
WO2018170083A1 (en) 2017-03-17 2018-09-20 Dow Global Technologies Llc Process for recovering an esterified cellulose ether from a reaction product mixture

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040242862A1 (en) * 2001-08-25 2004-12-02 Alf Hammes Method for producing a cellulose ether of low viscosity by means of acid oxidative decomposition of ground and dried cellulose ethers
JP2008501009A (ja) * 2004-05-28 2008-01-17 ファイザー・プロダクツ・インク 性能を高めた医薬組成物

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JPS59167521A (ja) * 1983-03-14 1984-09-21 Shin Etsu Chem Co Ltd 腸溶性コ−テイング剤組成物
JPS6281402A (ja) * 1985-10-07 1987-04-14 Shin Etsu Chem Co Ltd セルロ−スエ−テル酸性ジカルボン酸エステルの製造方法
JP3149122B2 (ja) 1994-11-07 2001-03-26 信越化学工業株式会社 固形腸溶製剤のコーティング用基剤
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KR100387126B1 (ko) 2001-04-19 2003-06-12 삼성정밀화학 주식회사 히드록시프로필메틸 셀룰로오스 프탈레이트의 분리정제방법
ATE371652T1 (de) 2002-05-17 2007-09-15 Tibotec Pharm Ltd Substituierte benzisoxazolsulfonamide mit breitbändiger hiv-protease hemmender wirkung
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JP5745855B2 (ja) * 2007-11-28 2015-07-08 セコイア、ファーマシューティカルズ、インコーポレイテッドＳｅｑｕｏｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． シトクロムｐ４５０ ２ｄ６を阻害するための組成物および方法
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US20120251588A1 (en) * 2011-03-30 2012-10-04 Miyuki Fukasawa Coating Composition, Solid Preparation Coated Therewith, and Method for Preparing Solid Preparation
EP2831121B1 (en) 2012-03-27 2018-10-10 Dow Global Technologies LLC A process of preparing an ester of a cellulose ether
KR20140146181A (ko) 2012-04-11 2014-12-24 다우 글로벌 테크놀로지스 엘엘씨 특정 치환체 분포를 갖는 에스테르화된 셀룰로즈 에테르
WO2014031418A1 (en) * 2012-08-24 2014-02-27 Dow Global Technologies Llc Partially cross-linked esterified cellulose ethers
WO2014031419A1 (en) * 2012-08-24 2014-02-27 Dow Global Technologies Llc Novel esterified cellulose ethers of high molecular weight and homogeneity
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Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040242862A1 (en) * 2001-08-25 2004-12-02 Alf Hammes Method for producing a cellulose ether of low viscosity by means of acid oxidative decomposition of ground and dried cellulose ethers
JP2008501009A (ja) * 2004-05-28 2008-01-17 ファイザー・プロダクツ・インク 性能を高めた医薬組成物

Also Published As

Publication number Publication date
WO2014137778A1 (en) 2014-09-12
EP2964204A1 (en) 2016-01-13
JP6267239B2 (ja) 2018-01-24
CN105025887A (zh) 2015-11-04
CN105025887B (zh) 2017-07-28
EP2964204B1 (en) 2017-01-04
KR20150119472A (ko) 2015-10-23
US9617351B2 (en) 2017-04-11
BR112015015846A2 (pt) 2017-07-11
JP2016516835A (ja) 2016-06-09
US20150376299A1 (en) 2015-12-31

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