KR101601987B1 - 신장 보호제로서 중쇄 길이 지방산 및 글리세라이드 - Google Patents

신장 보호제로서 중쇄 길이 지방산 및 글리세라이드 Download PDF

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Publication number
KR101601987B1
KR101601987B1 KR1020107012064A KR20107012064A KR101601987B1 KR 101601987 B1 KR101601987 B1 KR 101601987B1 KR 1020107012064 A KR1020107012064 A KR 1020107012064A KR 20107012064 A KR20107012064 A KR 20107012064A KR 101601987 B1 KR101601987 B1 KR 101601987B1
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kidney
composition
renal
compound
formula
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KR20100106958A (ko
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빈센트 피셰트
프랑수와 르블롱
마우나 라그라오우이
린 가뇽
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프로메틱 바이오사이언시즈 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020107012064A 2007-11-02 2008-11-03 신장 보호제로서 중쇄 길이 지방산 및 글리세라이드 Expired - Fee Related KR101601987B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98509407P 2007-11-02 2007-11-02
US60/985,094 2007-11-02

Publications (2)

Publication Number Publication Date
KR20100106958A KR20100106958A (ko) 2010-10-04
KR101601987B1 true KR101601987B1 (ko) 2016-03-09

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KR1020107012064A Expired - Fee Related KR101601987B1 (ko) 2007-11-02 2008-11-03 신장 보호제로서 중쇄 길이 지방산 및 글리세라이드

Country Status (19)

Country Link
US (1) US9532962B2 (enExample)
EP (1) EP2299998B1 (enExample)
JP (1) JP5575655B2 (enExample)
KR (1) KR101601987B1 (enExample)
CN (1) CN101878028A (enExample)
AU (1) AU2008318196B2 (enExample)
BR (1) BRPI0818310A8 (enExample)
CA (1) CA2704286C (enExample)
DK (1) DK2299998T3 (enExample)
ES (1) ES2664594T3 (enExample)
IL (1) IL205362A (enExample)
MX (1) MX338513B (enExample)
MY (1) MY151439A (enExample)
NO (1) NO2299998T3 (enExample)
NZ (1) NZ584981A (enExample)
PT (1) PT2299998T (enExample)
RU (1) RU2519215C2 (enExample)
WO (1) WO2009055933A1 (enExample)
ZA (1) ZA201003030B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2427416B1 (en) 2009-05-04 2016-03-09 Prometic Pharma Smt Limited Substituted aromatic compounds and pharmaceutical uses thereof
JP5706142B2 (ja) * 2010-04-28 2015-04-22 株式会社ファンケル フユボダイジュ花のエタノール抽出物を有効成分とする血中グルコース低下剤、内臓脂肪蓄積抑制剤、ｔｇ低下剤、糞中脂肪排泄促進剤
CN105997967B (zh) 2010-10-27 2019-08-23 普罗米蒂克医药Smt有限公司 用于治疗癌症的化合物和组合物
US9393224B2 (en) 2011-08-26 2016-07-19 Osaka University Prophylactic and/or therapeutic agent for cardiovascular complications of diabetes
KR20130023583A (ko) * 2011-08-29 2013-03-08 아주대학교산학협력단 파골세포 형성 억제 효과가 있는 카프르산 및 이를 포함하는 약학적 조성물
US10130603B2 (en) 2013-11-05 2018-11-20 Colgate-Palmolive Company Methods and compositions for improving kidney function
WO2017074266A1 (en) * 2015-10-30 2017-05-04 National University Of Singapore Androgen biosynthesis inhibitor
CN105559071A (zh) * 2016-01-12 2016-05-11 刘保惠 一种适用于肾病的特殊医学用途配方食品及其制备方法
JP2017214342A (ja) * 2016-06-02 2017-12-07 日清オイリオグループ株式会社 排尿障害の予防用又は改善用組成物
NZ749389A (en) 2016-06-08 2022-12-23 Sunregen Healthcare Ag Lipids with odd number of carbon atoms and their use as pharmaceutical composition or nutritional supplement
WO2018115953A1 (en) * 2016-12-21 2018-06-28 Prometic Pharma Smt Limited Methods and compositions for preventing or minimizing epithelial-mesenchymal transition
JP7055429B2 (ja) * 2017-10-27 2022-04-18 学校法人北里研究所 慢性腎臓病の予防又は治療剤
US20190240180A1 (en) * 2018-02-08 2019-08-08 Nestec Sa Mct-based nutrition blend for providing health benefits in companion animals
MA53188A1 (fr) 2018-10-11 2021-12-31 Basf As Composés aromatiques et leurs utilisations pharmaceutiques
CN109602012A (zh) * 2018-12-11 2019-04-12 李卫平 一种功能性低蛋白能量米及其制备方法
CN111184728B (zh) * 2020-02-20 2023-04-04 上海市儿童医院 海藻糖在肾病综合征中的应用
EP4539686A1 (en) * 2022-06-15 2025-04-23 Hill's Pet Nutrition, Inc. Pet food compositions
JP2024176004A (ja) * 2023-06-07 2024-12-19 リファインホールディングス株式会社 小胞体ストレス抑制剤、慢性腎臓病疾患予防改善剤および食品
CN118592613B (zh) * 2024-08-05 2025-01-07 杭州康源食品科技有限公司 中链脂肪酸混合结构脂在改善膳食诱导的糖脂代谢紊乱中的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0583480A1 (en) 1992-02-07 1994-02-23 TSUMURA & CO. Side-effect alleviant
JP2004525180A (ja) 2001-04-11 2004-08-19 イエダ リサーチ アンド デベロップメント カンパニー リミテッド 炎症の治療に有用な脂肪族アルコール及び脂肪酸エステル
WO2007117272A2 (en) 2005-09-30 2007-10-18 The Henry M. Jackson Foundation For The Advancement Of Military Medicine Methods for treatment of hemorrhagic shock and related disorders

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4602040A (en) 1983-04-18 1986-07-22 Warner-Lambert Company Meclofenamic acid topical pharmaceutical composition
US4737384A (en) * 1985-11-01 1988-04-12 Allied Corporation Deposition of thin films using supercritical fluids
US6689700B1 (en) * 1999-11-02 2004-02-10 University Of Massachusetts Chemical fluid deposition method for the formation of metal and metal alloy films on patterned and unpatterned substrates
JP5259905B2 (ja) 2000-06-20 2013-08-07 エヌ・ブイ・ニュートリション・サイエンシス 抗菌剤として適用可能な中鎖脂肪酸
DK1900364T3 (da) * 2001-04-18 2014-01-13 Prometic Biosciences Inc Fedtsyrer, glycerider og analoger med medium kædelængde som neutrofile overlevelses- og aktiveringsfaktorer
CN1827766B (zh) 2001-06-28 2010-08-25 徐荣祥 体外细胞的培养方法
RU2213570C2 (ru) * 2001-08-22 2003-10-10 Санкт-Петербургская Государственная Химико-Фармацевтическая Академия ЛЕЧЕБНО-ПРОФИЛАКТИЧЕСКОЕ СРЕДСТВО ИЗ ЛИСТЬЕВ ЛИПЫ Folia Tilia И СПОСОБ ПОЛУЧЕНИЯ ЭКСТРАКТИВНЫХ ВЕЩЕСТВ
US7030168B2 (en) * 2001-12-31 2006-04-18 Advanced Technology Materials, Inc. Supercritical fluid-assisted deposition of materials on semiconductor substrates
US20040052836A1 (en) * 2002-09-13 2004-03-18 Li Luk Chiu Pharmaceutical compositions containing at least one stable liposphere having an improved shelf life
BRPI0407276A (pt) 2003-02-07 2006-01-31 Prometic Biosciences Inc ácidos graxos, glicerìdeos e análogos com comprimento de cadeia médio, como estimulantes de eritropoiese
PL1648851T3 (pl) 2003-07-25 2007-09-28 Prometic Biosciences Inc Wytwarzanie soli średniołańcuchowych kwasów tłuszczowych z metalami

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0583480A1 (en) 1992-02-07 1994-02-23 TSUMURA & CO. Side-effect alleviant
JP2004525180A (ja) 2001-04-11 2004-08-19 イエダ リサーチ アンド デベロップメント カンパニー リミテッド 炎症の治療に有用な脂肪族アルコール及び脂肪酸エステル
WO2007117272A2 (en) 2005-09-30 2007-10-18 The Henry M. Jackson Foundation For The Advancement Of Military Medicine Methods for treatment of hemorrhagic shock and related disorders

Also Published As

Publication number Publication date
WO2009055933A1 (en) 2009-05-07
CA2704286A1 (en) 2009-05-07
US20100286269A1 (en) 2010-11-11
JP5575655B2 (ja) 2014-08-20
ES2664594T3 (es) 2018-04-20
BRPI0818310A2 (pt) 2017-10-10
EP2299998B1 (en) 2018-01-03
EP2299998A1 (en) 2011-03-30
JP2011502174A (ja) 2011-01-20
PT2299998T (pt) 2018-04-02
NZ584981A (en) 2012-05-25
IL205362A0 (en) 2010-12-30
ZA201003030B (en) 2011-02-23
DK2299998T3 (en) 2018-03-26
US9532962B2 (en) 2017-01-03
AU2008318196A1 (en) 2009-05-07
EP2299998A4 (en) 2011-03-30
BRPI0818310A8 (pt) 2017-12-26
MX2010004856A (es) 2010-06-30
AU2008318196B2 (en) 2014-04-10
CN101878028A (zh) 2010-11-03
RU2010122302A (ru) 2011-12-10
MX338513B (es) 2016-04-20
MY151439A (en) 2014-05-30
KR20100106958A (ko) 2010-10-04
RU2519215C2 (ru) 2014-06-10
CA2704286C (en) 2016-08-23
IL205362A (en) 2015-01-29
NO2299998T3 (enExample) 2018-06-02

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