DK2299998T3 - MEDIUM-CHAINED FAT ACIDS AND GLYCERIDES AS NEPHROB PROTECTIVES - Google Patents
MEDIUM-CHAINED FAT ACIDS AND GLYCERIDES AS NEPHROB PROTECTIVES Download PDFInfo
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- DK2299998T3 DK2299998T3 DK08845122.4T DK08845122T DK2299998T3 DK 2299998 T3 DK2299998 T3 DK 2299998T3 DK 08845122 T DK08845122 T DK 08845122T DK 2299998 T3 DK2299998 T3 DK 2299998T3
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- Denmark
- Prior art keywords
- compound
- use according
- kidney
- equal
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- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 description 1
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- 231100000827 tissue damage Toxicity 0.000 description 1
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- 238000013518 transcription Methods 0.000 description 1
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- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 208000037999 tubulointerstitial fibrosis Diseases 0.000 description 1
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US98509407P | 2007-11-02 | 2007-11-02 | |
| PCT/CA2008/001930 WO2009055933A1 (en) | 2007-11-02 | 2008-11-03 | Medium-chain length fatty acids and glycerides as nephroprotection agents |
Publications (1)
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| DK2299998T3 true DK2299998T3 (en) | 2018-03-26 |
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| RU (1) | RU2519215C2 (enExample) |
| WO (1) | WO2009055933A1 (enExample) |
| ZA (1) | ZA201003030B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2012526052A (ja) | 2009-05-04 | 2012-10-25 | プロメティック・バイオサイエンシーズ・インコーポレイテッド | 置換芳香族化合物およびその薬学的使用 |
| JP5706142B2 (ja) * | 2010-04-28 | 2015-04-22 | 株式会社ファンケル | フユボダイジュ花のエタノール抽出物を有効成分とする血中グルコース低下剤、内臓脂肪蓄積抑制剤、ｔｇ低下剤、糞中脂肪排泄促進剤 |
| AU2011356583C1 (en) * | 2010-10-27 | 2016-03-17 | Liminal Biosciences Limited | Compounds and compositions for the treatment of cancer |
| WO2013031729A1 (ja) * | 2011-08-26 | 2013-03-07 | 国立大学法人大阪大学 | 糖尿病性心血管合併症の予防・治療剤 |
| KR20130023583A (ko) * | 2011-08-29 | 2013-03-08 | 아주대학교산학협력단 | 파골세포 형성 억제 효과가 있는 카프르산 및 이를 포함하는 약학적 조성물 |
| CA2926599C (en) * | 2013-11-05 | 2021-05-04 | Hill's Pet Nutrition, Inc. | Methods and compositions for improving kidney function |
| WO2017074266A1 (en) * | 2015-10-30 | 2017-05-04 | National University Of Singapore | Androgen biosynthesis inhibitor |
| CN105559071A (zh) * | 2016-01-12 | 2016-05-11 | 刘保惠 | 一种适用于肾病的特殊医学用途配方食品及其制备方法 |
| JP2017214342A (ja) * | 2016-06-02 | 2017-12-07 | 日清オイリオグループ株式会社 | 排尿障害の予防用又は改善用組成物 |
| CN117298092A (zh) | 2016-06-08 | 2023-12-29 | 善睿圣医药保健股份有限公司 | 具有奇数碳的脂类化合物及其作为医药组合物或者营养补充剂的用途 |
| RU2764630C2 (ru) * | 2016-12-21 | 2022-01-19 | Лиминал Байосайенсиз Лимитед | Способы и композиции для предотвращения или минимизации эпителиально-мезенхимального перехода |
| WO2019082912A1 (ja) * | 2017-10-27 | 2019-05-02 | 学校法人北里研究所 | 慢性腎臓病の予防又は治療剤 |
| WO2019155336A1 (en) * | 2018-02-08 | 2019-08-15 | Societe Des Produits Nestle S.A. | Mct-based nutrition blend for providing health benefits in companion animals |
| AU2019358595B2 (en) | 2018-10-11 | 2025-04-17 | Basf As | Aromatic compounds and pharmaceutical uses thereof |
| CN109602012A (zh) * | 2018-12-11 | 2019-04-12 | 李卫平 | 一种功能性低蛋白能量米及其制备方法 |
| CN111184728B (zh) * | 2020-02-20 | 2023-04-04 | 上海市儿童医院 | 海藻糖在肾病综合征中的应用 |
| WO2023244709A1 (en) * | 2022-06-15 | 2023-12-21 | Hill's Pet Nutrition, Inc. | Pet food compositions |
| CN118592613B (zh) * | 2024-08-05 | 2025-01-07 | 杭州康源食品科技有限公司 | 中链脂肪酸混合结构脂在改善膳食诱导的糖脂代谢紊乱中的应用 |
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| US4602040A (en) | 1983-04-18 | 1986-07-22 | Warner-Lambert Company | Meclofenamic acid topical pharmaceutical composition |
| US4737384A (en) * | 1985-11-01 | 1988-04-12 | Allied Corporation | Deposition of thin films using supercritical fluids |
| AU651758B2 (en) | 1992-02-07 | 1994-07-28 | Tsumura & Co. | Side-effect alleviant |
| US6689700B1 (en) * | 1999-11-02 | 2004-02-10 | University Of Massachusetts | Chemical fluid deposition method for the formation of metal and metal alloy films on patterned and unpatterned substrates |
| JP5259905B2 (ja) | 2000-06-20 | 2013-08-07 | エヌ・ブイ・ニュートリション・サイエンシス | 抗菌剤として適用可能な中鎖脂肪酸 |
| IL142535A0 (en) | 2001-04-11 | 2002-03-10 | Yeda Res & Dev | Pharmaceutical compositions for the treatment of inflammation |
| PT1900364E (pt) | 2001-04-18 | 2013-12-19 | Prometic Biosciences Inc | Ácidos gordos de cadeia de comprimento médio, glicéridos e análogos como fatores de sobrevivência e ativação de neutrófilos |
| CN1827766B (zh) * | 2001-06-28 | 2010-08-25 | 徐荣祥 | 体外细胞的培养方法 |
| RU2213570C2 (ru) * | 2001-08-22 | 2003-10-10 | Санкт-Петербургская Государственная Химико-Фармацевтическая Академия | ЛЕЧЕБНО-ПРОФИЛАКТИЧЕСКОЕ СРЕДСТВО ИЗ ЛИСТЬЕВ ЛИПЫ Folia Tilia И СПОСОБ ПОЛУЧЕНИЯ ЭКСТРАКТИВНЫХ ВЕЩЕСТВ |
| US7030168B2 (en) * | 2001-12-31 | 2006-04-18 | Advanced Technology Materials, Inc. | Supercritical fluid-assisted deposition of materials on semiconductor substrates |
| US20040052836A1 (en) * | 2002-09-13 | 2004-03-18 | Li Luk Chiu | Pharmaceutical compositions containing at least one stable liposphere having an improved shelf life |
| ES2255467T3 (es) | 2003-02-07 | 2009-05-01 | Prometic Biosciences Inc. | Acidos grasos de cadena de longitud media, gliceridos y analogos como estimuladores de eritropoyesis. |
| AU2004261461B2 (en) | 2003-07-25 | 2008-12-18 | Prometic Pharma Smt Limited | Preparation of metal salts of medium-chain fatty acids |
| WO2007117272A2 (en) | 2005-09-30 | 2007-10-18 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine | Methods for treatment of hemorrhagic shock and related disorders |
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2008
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- 2008-11-03 BR BRPI0818310A patent/BRPI0818310A8/pt not_active IP Right Cessation
- 2008-11-03 JP JP2010532389A patent/JP5575655B2/ja not_active Expired - Fee Related
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- 2008-11-03 PT PT88451224T patent/PT2299998T/pt unknown
- 2008-11-03 MY MYPI2010001861A patent/MY151439A/en unknown
- 2008-11-03 DK DK08845122.4T patent/DK2299998T3/en active
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Also Published As
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| NZ584981A (en) | 2012-05-25 |
| MX2010004856A (es) | 2010-06-30 |
| PT2299998T (pt) | 2018-04-02 |
| BRPI0818310A2 (pt) | 2017-10-10 |
| EP2299998A1 (en) | 2011-03-30 |
| MY151439A (en) | 2014-05-30 |
| IL205362A (en) | 2015-01-29 |
| JP2011502174A (ja) | 2011-01-20 |
| MX338513B (es) | 2016-04-20 |
| AU2008318196B2 (en) | 2014-04-10 |
| EP2299998A4 (en) | 2011-03-30 |
| NO2299998T3 (enExample) | 2018-06-02 |
| US20100286269A1 (en) | 2010-11-11 |
| CA2704286A1 (en) | 2009-05-07 |
| CN101878028A (zh) | 2010-11-03 |
| RU2519215C2 (ru) | 2014-06-10 |
| US9532962B2 (en) | 2017-01-03 |
| EP2299998B1 (en) | 2018-01-03 |
| AU2008318196A1 (en) | 2009-05-07 |
| ZA201003030B (en) | 2011-02-23 |
| RU2010122302A (ru) | 2011-12-10 |
| KR20100106958A (ko) | 2010-10-04 |
| IL205362A0 (en) | 2010-12-30 |
| ES2664594T3 (es) | 2018-04-20 |
| CA2704286C (en) | 2016-08-23 |
| JP5575655B2 (ja) | 2014-08-20 |
| BRPI0818310A8 (pt) | 2017-12-26 |
| KR101601987B1 (ko) | 2016-03-09 |
| WO2009055933A1 (en) | 2009-05-07 |
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