CN101878028A - 作为肾保护剂的中链长度脂肪酸和甘油酯 - Google Patents

作为肾保护剂的中链长度脂肪酸和甘油酯 Download PDF

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Publication number
CN101878028A
CN101878028A CN200880113724XA CN200880113724A CN101878028A CN 101878028 A CN101878028 A CN 101878028A CN 200880113724X A CN200880113724X A CN 200880113724XA CN 200880113724 A CN200880113724 A CN 200880113724A CN 101878028 A CN101878028 A CN 101878028A
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CN
China
Prior art keywords
formula
compounds
composition
renal
delays
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Pending
Application number
CN200880113724XA
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English (en)
Chinese (zh)
Inventor
V·皮切特
F·勒布隆
M·拉格拉欧伊
L·加尼翁
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Prometic Biosciences Inc
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Prometic Biosciences Inc
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Application filed by Prometic Biosciences Inc filed Critical Prometic Biosciences Inc
Publication of CN101878028A publication Critical patent/CN101878028A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN200880113724XA 2007-11-02 2008-11-03 作为肾保护剂的中链长度脂肪酸和甘油酯 Pending CN101878028A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98509407P 2007-11-02 2007-11-02
US60/985094 2007-11-02
PCT/CA2008/001930 WO2009055933A1 (en) 2007-11-02 2008-11-03 Medium-chain length fatty acids and glycerides as nephroprotection agents

Publications (1)

Publication Number Publication Date
CN101878028A true CN101878028A (zh) 2010-11-03

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880113724XA Pending CN101878028A (zh) 2007-11-02 2008-11-03 作为肾保护剂的中链长度脂肪酸和甘油酯

Country Status (19)

Country Link
US (1) US9532962B2 (enExample)
EP (1) EP2299998B1 (enExample)
JP (1) JP5575655B2 (enExample)
KR (1) KR101601987B1 (enExample)
CN (1) CN101878028A (enExample)
AU (1) AU2008318196B2 (enExample)
BR (1) BRPI0818310A8 (enExample)
CA (1) CA2704286C (enExample)
DK (1) DK2299998T3 (enExample)
ES (1) ES2664594T3 (enExample)
IL (1) IL205362A (enExample)
MX (1) MX338513B (enExample)
MY (1) MY151439A (enExample)
NO (1) NO2299998T3 (enExample)
NZ (1) NZ584981A (enExample)
PT (1) PT2299998T (enExample)
RU (1) RU2519215C2 (enExample)
WO (1) WO2009055933A1 (enExample)
ZA (1) ZA201003030B (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103945840A (zh) * 2011-08-26 2014-07-23 国立大学法人大阪大学 糖尿病性心血管并发症的预防/治疗剂
CN105559071A (zh) * 2016-01-12 2016-05-11 刘保惠 一种适用于肾病的特殊医学用途配方食品及其制备方法
CN109602012A (zh) * 2018-12-11 2019-04-12 李卫平 一种功能性低蛋白能量米及其制备方法
CN110290786A (zh) * 2016-12-21 2019-09-27 普罗米蒂克医药Smt有限公司 用于预防或最小化上皮细胞-间充质细胞转换的方法和组合物
CN111184728A (zh) * 2020-02-20 2020-05-22 上海市儿童医院 海藻糖在肾病综合征中的应用

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010127440A1 (en) 2009-05-04 2010-11-11 Prometic Biosciences Inc. Substituted aromatic compounds and pharmaceutical uses thereof
JP5706142B2 (ja) * 2010-04-28 2015-04-22 株式会社ファンケル フユボダイジュ花のエタノール抽出物を有効成分とする血中グルコース低下剤、内臓脂肪蓄積抑制剤、ｔｇ低下剤、糞中脂肪排泄促進剤
DK3443957T3 (da) 2010-10-27 2020-12-21 Liminal Biosciences Ltd Forbindelser og sammensætninger til behandling af cancer
KR20130023583A (ko) * 2011-08-29 2013-03-08 아주대학교산학협력단 파골세포 형성 억제 효과가 있는 카프르산 및 이를 포함하는 약학적 조성물
EP3065731B1 (en) 2013-11-05 2018-10-24 Hill's Pet Nutrition, Inc. Methods and compositions for improving kidney function
WO2017074266A1 (en) * 2015-10-30 2017-05-04 National University Of Singapore Androgen biosynthesis inhibitor
JP2017214342A (ja) * 2016-06-02 2017-12-07 日清オイリオグループ株式会社 排尿障害の予防用又は改善用組成物
TWI749016B (zh) 2016-06-08 2021-12-11 董宇紅 具有奇數碳的脂類化合物及其作為醫藥組合物或者營養補充劑的用途
JP7055429B2 (ja) * 2017-10-27 2022-04-18 学校法人北里研究所 慢性腎臓病の予防又は治療剤
WO2019155336A1 (en) * 2018-02-08 2019-08-15 Societe Des Produits Nestle S.A. Mct-based nutrition blend for providing health benefits in companion animals
CA3112073A1 (en) 2018-10-11 2020-04-16 Basf As Aromatic compounds and pharmaceutical uses thereof
US20230404957A1 (en) * 2022-06-15 2023-12-21 Hill's Pet Nutrition, Inc. Pet Food Compositions
CN118592613B (zh) * 2024-08-05 2025-01-07 杭州康源食品科技有限公司 中链脂肪酸混合结构脂在改善膳食诱导的糖脂代谢紊乱中的应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4602040A (en) 1983-04-18 1986-07-22 Warner-Lambert Company Meclofenamic acid topical pharmaceutical composition
US4737384A (en) * 1985-11-01 1988-04-12 Allied Corporation Deposition of thin films using supercritical fluids
EP0583480A4 (en) 1992-02-07 1994-03-18 Tsumura & Co SIDE EFFECTS MITIGATION AGENT.
US6689700B1 (en) * 1999-11-02 2004-02-10 University Of Massachusetts Chemical fluid deposition method for the formation of metal and metal alloy films on patterned and unpatterned substrates
CN100348183C (zh) 2000-06-20 2007-11-14 营养科学公司 可用作抗微生物剂的中链脂肪酸
IL142535A0 (en) * 2001-04-11 2002-03-10 Yeda Res & Dev Pharmaceutical compositions for the treatment of inflammation
CA2444463C (en) * 2001-04-18 2012-03-20 Prometic Biosciences Inc. Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors
CN1827766B (zh) 2001-06-28 2010-08-25 徐荣祥 体外细胞的培养方法
RU2213570C2 (ru) * 2001-08-22 2003-10-10 Санкт-Петербургская Государственная Химико-Фармацевтическая Академия ЛЕЧЕБНО-ПРОФИЛАКТИЧЕСКОЕ СРЕДСТВО ИЗ ЛИСТЬЕВ ЛИПЫ Folia Tilia И СПОСОБ ПОЛУЧЕНИЯ ЭКСТРАКТИВНЫХ ВЕЩЕСТВ
US7030168B2 (en) * 2001-12-31 2006-04-18 Advanced Technology Materials, Inc. Supercritical fluid-assisted deposition of materials on semiconductor substrates
US20040052836A1 (en) * 2002-09-13 2004-03-18 Li Luk Chiu Pharmaceutical compositions containing at least one stable liposphere having an improved shelf life
DE04708802T1 (de) 2003-02-07 2006-06-22 Prometic Biosciences Inc., Montreal Fettsäuren mittlerer kettenlänge, glyceride und analoga als stimulatoren der erythropoiese
DE602004006137T3 (de) 2003-07-25 2012-01-19 Prometic Biosciences Inc. Herstellung von metallsalzen von fettsäuren mit mittlerer kettenlänge
EP1940379A4 (en) 2005-09-30 2009-05-13 Jackson H M Found Military Med METHOD FOR THE TREATMENT OF HEMORRHAGIC SHOCKS AND ASSOCIATED DISEASES

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103945840A (zh) * 2011-08-26 2014-07-23 国立大学法人大阪大学 糖尿病性心血管并发症的预防/治疗剂
US9393224B2 (en) 2011-08-26 2016-07-19 Osaka University Prophylactic and/or therapeutic agent for cardiovascular complications of diabetes
CN105559071A (zh) * 2016-01-12 2016-05-11 刘保惠 一种适用于肾病的特殊医学用途配方食品及其制备方法
CN110290786A (zh) * 2016-12-21 2019-09-27 普罗米蒂克医药Smt有限公司 用于预防或最小化上皮细胞-间充质细胞转换的方法和组合物
CN109602012A (zh) * 2018-12-11 2019-04-12 李卫平 一种功能性低蛋白能量米及其制备方法
CN111184728A (zh) * 2020-02-20 2020-05-22 上海市儿童医院 海藻糖在肾病综合征中的应用

Also Published As

Publication number Publication date
KR20100106958A (ko) 2010-10-04
CA2704286C (en) 2016-08-23
MX338513B (es) 2016-04-20
RU2519215C2 (ru) 2014-06-10
KR101601987B1 (ko) 2016-03-09
EP2299998A4 (en) 2011-03-30
EP2299998A1 (en) 2011-03-30
AU2008318196B2 (en) 2014-04-10
RU2010122302A (ru) 2011-12-10
AU2008318196A1 (en) 2009-05-07
IL205362A0 (en) 2010-12-30
NO2299998T3 (enExample) 2018-06-02
ES2664594T3 (es) 2018-04-20
BRPI0818310A2 (pt) 2017-10-10
EP2299998B1 (en) 2018-01-03
IL205362A (en) 2015-01-29
ZA201003030B (en) 2011-02-23
DK2299998T3 (en) 2018-03-26
CA2704286A1 (en) 2009-05-07
US20100286269A1 (en) 2010-11-11
MY151439A (en) 2014-05-30
BRPI0818310A8 (pt) 2017-12-26
NZ584981A (en) 2012-05-25
JP5575655B2 (ja) 2014-08-20
MX2010004856A (es) 2010-06-30
JP2011502174A (ja) 2011-01-20
US9532962B2 (en) 2017-01-03
PT2299998T (pt) 2018-04-02
WO2009055933A1 (en) 2009-05-07

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